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Exploring potential neuroimaging biomarkers for the response to non-steroidal anti-inflammatory drugs in episodic migraine
Exploring potential neuroimaging biomarkers for the response to non-steroidal anti-inflammatory drugs in episodic migraine
Non-steroidal anti-inflammatory drugs (NSAIDs) are considered first-line medications for acute migraine attacks. However, ...
Hypersensitivity to BKCa channel opening in persistent post-traumatic headache
Hypersensitivity to BKCa channel opening in persistent post-traumatic headache
Large conductance  calcium-activated potassium (BKCa) channels have been implicated in the neurobiological underp...
Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization
Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization
Currently, the treatment and prevention of migraine remain highly challenging. Mendelian randomization (MR) has been widel...
Shifts in structural connectome organization in the limbic and sensory systems of patients with episodic migraine
Shifts in structural connectome organization in the limbic and sensory systems of patients with episodic migraine
Migraine is a complex neurological condition characterized by recurrent headaches, which is often accompanied by various n...
PACAP-38 and sex hormones in women with migraine: exploratory analysis of a cross-sectional, matched cohort study
PACAP-38 and sex hormones in women with migraine: exploratory analysis of a cross-sectional, matched cohort study
Endogeneous and exogeneous sex hormones can impact the frequency and severity of migraine attacks, but the underlying mech...
Altered immunity in migraine: a comprehensive scoping review
Altered immunity in migraine: a comprehensive scoping review
The pathogenesis of migraine remains unclear; however, a large body of evidence supports the hypothesis that immunological...
Plasma calcitonin gene-related peptide levels in idiopathic intracranial hypertension: an exploratory study
Plasma calcitonin gene-related peptide levels in idiopathic intracranial hypertension: an exploratory study
Idiopathic intracranial hypertension (IIH) is a debilitating condition characterized by increased intracranial pressure of...
A cross-tissue transcriptome-wide association study reveals novel susceptibility genes for migraine
A cross-tissue transcriptome-wide association study reveals novel susceptibility genes for migraine
Migraine is a common neurological disorder with a strong genetic component. Despite the identification of over 100 loci as...
Genetic evidence for the causal relationships between migraine, dementia, and longitudinal brain atrophy
Genetic evidence for the causal relationships between migraine, dementia, and longitudinal brain atrophy
Migraine is a neurological disease with a significant genetic component and is characterized by recurrent and prolonged ep...
Medication-overuse headache: a narrative review
Medication-overuse headache: a narrative review
Medication-overuse headache (MOH), which potentially involves 1–2% of the population, is defined as a headache, on &...
PACAP38/mast-cell-specific receptor axis mediates repetitive stress-induced headache in mice
PACAP38/mast-cell-specific receptor axis mediates repetitive stress-induced headache in mice
Pain, an evolutionarily conserved warning system, lets us recognize threats and motivates us to adapt to those threats. He...
MERTK in the rat trigeminal system: a potential novel target for cluster headache?
MERTK in the rat trigeminal system: a potential novel target for cluster headache?
The trigeminal system is key to the pathophysiology of migraine and cluster headache, two primary headache disorders that ...
Aberrant cerebral blood flow and functional connectivity in patients with vestibular migraine: a resting-state ASL and fMRI study
Aberrant cerebral blood flow and functional connectivity in patients with vestibular migraine: a resting-state ASL and fMRI study
Prior neuroimaging studies on vestibular migraine (VM) have extensively certified the functional and structural alteration...
Poor healthy lifestyle and life’s essential 8 are associated with higher risk of new-onset migraine: a prospective cohort study
Poor healthy lifestyle and life’s essential 8 are associated with higher risk of new-onset migraine: a prospective cohort study
Lifestyle are closely related to migraine. However, there is a lack of studies investigating the association between Healt...
Migraine or any headaches and white matter hyperintensities and their progression in women and men
Migraine or any headaches and white matter hyperintensities and their progression in women and men
Cross-sectional and longitudinal studies have been conducted to investigate the association between migraine and any heada...
MicroRNA profiling in women with migraine: effects of CGRP-targeting treatment
MicroRNA profiling in women with migraine: effects of CGRP-targeting treatment
Migraine lacks biomarkers that can trace the biological pathways of the disease and predict the effectiveness of treatment...
Alleviation of migraine related pain and anxiety by inhibiting calcium-stimulating AC1-dependent CGRP in the insula of adult rats
Alleviation of migraine related pain and anxiety by inhibiting calcium-stimulating AC1-dependent CGRP in the insula of adult rats
Recent animal and clinical findings consistently highlight the critical role of calcitonin gene-related peptide (CGRP) in ...
Deciphering the functional role of insular cortex stratification in trigeminal neuropathic pain
Deciphering the functional role of insular cortex stratification in trigeminal neuropathic pain
Trigeminal neuropathic pain (TNP) is a major concern in both dentistry and medicine. The progression from normal to chroni...
Extrasynaptic δGABAA receptors mediate resistance to migraine-like phenotype in rats
Extrasynaptic δGABAA receptors mediate resistance to migraine-like phenotype in rats
GABA, a key inhibitory neurotransmitter, has synaptic and extrasynaptic receptors on the postsynaptic neuron. Background G...