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Efficacy and safety of intranasal agents for the acute treatment of migraine: a systematic review and network meta-analysis
Efficacy and safety of intranasal agents for the acute treatment of migraine: a systematic review and network meta-analysis
Intranasal agents may be ideal for the treatment of migraine patients. Many new acute intranasal-specific therapies have b...
Quality of life in children suffering from headaches: a systematic literature review
Quality of life in children suffering from headaches: a systematic literature review
Headaches are the most common complaints among pediatric populations. Determining the cause and appropriate treatment for ...
Serum tau protein elevation in migraine: a cross-sectional case–control study
Serum tau protein elevation in migraine: a cross-sectional case–control study
Migraine is a disorder associated with neuropeptide release, pain and inflammation. Tau protein has recently been linked t...
Mode and site of action of therapies targeting CGRP signaling
Mode and site of action of therapies targeting CGRP signaling
Targeting CGRP has proved to be efficacious, tolerable, and safe to treat migraine; however, many patients with migraine d...
Investigating the relationship between sleep and migraine in a global sample: a Bayesian cross-sectional approach
Investigating the relationship between sleep and migraine in a global sample: a Bayesian cross-sectional approach
There is a bidirectional link between sleep and migraine, however causality is difficult to determine. This study aimed to...
Calcitonin gene-related peptide causes migraine aura
Calcitonin gene-related peptide causes migraine aura
Although the involvement of calcitonin gene-related peptide (CGRP) in migraines is well-established, its specific role in ...
Proteomics profiling reveals mitochondrial damage in the thalamus in a mouse model of chronic migraine
Proteomics profiling reveals mitochondrial damage in the thalamus in a mouse model of chronic migraine
Migraine, a complex brain disorder, is regarded as a possible clinical manifestation of brain energy dysfunction. The trig...
Who cares about migraine? Pathways and hurdles in the European region - access to care III
Who cares about migraine? Pathways and hurdles in the European region - access to care III
Migraine is a highly prevalent primary headache disorder and a leading cause of disability. Difficulties in access to care...
Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China
Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China
Headache disorders are widely prevalent and pose a considerable economic burden on individuals and society. Globally, misd...
Cutaneous allodynia as predictor for treatment response in chronic migraine: a cohort study
Cutaneous allodynia as predictor for treatment response in chronic migraine: a cohort study
Central sensitisation is an important mechanism in migraine chronification. It is presumed to occur in second and third or...
Relationship between alcohol and primary headaches: a systematic review and meta-analysis
Relationship between alcohol and primary headaches: a systematic review and meta-analysis
Headache is one of the most common neurological symptoms. Many previous studies have indicated a relationship between prim...
Adiponectin receptor 1-mediated stimulation of Cav3.2 channels in trigeminal ganglion neurons induces nociceptive behaviors in mice
Adiponectin receptor 1-mediated stimulation of Cav3.2 channels in trigeminal ganglion neurons induces nociceptive behaviors in mice
Adipokines, including adiponectin, are implicated in nociceptive pain; however, the underlying cellular and molecular mech...
Advanced brain MRI may help understand the link between migraine and multiple sclerosis
Advanced brain MRI may help understand the link between migraine and multiple sclerosis
There is a clinical association between migraine and multiple sclerosis. Migraine and MS patients share similar demographi...
Lipids, lipid-modifying drug target genes and migraine: a Mendelian randomization study
Lipids, lipid-modifying drug target genes and migraine: a Mendelian randomization study
Migraine, a prevalent headache disorder with unclear mechanisms and limited treatments, may be influenced by dyslipidemia ...
Phenotype of new daily persistent headache: subtypes and comparison to transformed chronic daily headache
Phenotype of new daily persistent headache: subtypes and comparison to transformed chronic daily headache
It is unknown whether new daily persistent headache (NDPH) is a single disorder or heterogenous group of disorders, and wh...
Identifying causal genes for migraine by integrating the proteome and transcriptome
Identifying causal genes for migraine by integrating the proteome and transcriptome
While previous genome-wide association studies (GWAS) have identified multiple risk variants for migraine, there is a lack...
Correction: Changes of migraine aura with advancing age of patients
Correction: Changes of migraine aura with advancing age of patients
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Neuroimaging in the pre-ictal or premonitory phase of migraine: a narrative review
Neuroimaging in the pre-ictal or premonitory phase of migraine: a narrative review
The premonitory phase, or prodrome, of migraine, provides valuable opportunities to study attack initiation and for treati...
Mechanisms of initiation of cortical spreading depression
Mechanisms of initiation of cortical spreading depression
There is increasing evidence from human and animal studies that cortical spreading depression (CSD) is the neurophysiologi...
Galcanezumab in patients with episodic migraine: results from the open-label period of the phase 3 PERSIST study
Galcanezumab in patients with episodic migraine: results from the open-label period of the phase 3 PERSIST study
The phase 3 randomized PERSIST study demonstrated the efficacy and tolerability of galcanezumab, a humanized anti-calciton...
Changes of migraine aura with advancing age of patients
Changes of migraine aura with advancing age of patients
Given the similar presentation of migraine aura and acute ischemic stroke, advancing patient age might change the characte...