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An economic evaluation of eptinezumab for the preventive treatment of migraine in the UK, with consideration for natural history and work productivity
An economic evaluation of eptinezumab for the preventive treatment of migraine in the UK, with consideration for natural history and work productivity
Migraine is a highly prevalent neurological disease with a substantial societal burden due to lost productivity. From a so...
Dynamic fluctuations of salivary CGRP levels during migraine attacks: association with clinical variables and phenotypic characterization
Dynamic fluctuations of salivary CGRP levels during migraine attacks: association with clinical variables and phenotypic characterization
Migraine is a complex neurological disorder with significant heterogeneity in its clinical presentation and molecular mech...
Healthcare utilisation and economic burden of migraines among bank employees in China: a probabilistic modelling study
Healthcare utilisation and economic burden of migraines among bank employees in China: a probabilistic modelling study
Despite the recognised high prevalence of migraines among bank employees, yet their healthcare utilisation patterns and th...
Effects of PDE-3 inhibition in persistent post-traumatic headache: evidence of cAMP-dependent signaling
Effects of PDE-3 inhibition in persistent post-traumatic headache: evidence of cAMP-dependent signaling
Phosphodiesterase 3 (PDE-3) inhibition have been implicated in the neurobiologic underpinnings of migraine. Considering th...
Rimegepant orally disintegrating tablet 75 mg for acute treatment of migraine in adults from China: a subgroup analysis of a double-blind, randomized, placebo-controlled, phase 3 clinical trial
Rimegepant orally disintegrating tablet 75 mg for acute treatment of migraine in adults from China: a subgroup analysis of a double-blind, randomized, placebo-controlled, phase 3 clinical trial
Rimegepant orally disintegrating tablet (ODT), an oral small-molecule calcitonin gene-related peptide receptor antagonist,...
Reconceptualizing autonomic function testing in migraine: a systematic review and meta-analysis
Reconceptualizing autonomic function testing in migraine: a systematic review and meta-analysis
Autonomic nervous system (ANS) testing has aided in our ability to evaluate autonomic dysfunction in migraine patients. We...
Alterations of the alpha rhythm in visual snow syndrome: a case-control study
Alterations of the alpha rhythm in visual snow syndrome: a case-control study
Visual snow syndrome is a disorder characterized by the combination of typical perceptual disturbances. The clinical pictu...
The prevalence and demographic associations of headache in the adult population of Benin: a cross-sectional population-based study
The prevalence and demographic associations of headache in the adult population of Benin: a cross-sectional population-based study
The Global Burden of Disease (GBD) study is increasingly well informed with regard to headache disorders, but sub-Saharan ...
CGRP-targeted medication in chronic migraine - systematic review
CGRP-targeted medication in chronic migraine - systematic review
Chronic migraine is a highly debilitating condition that is often difficult to manage, particularly in the presence of med...
Unveiling the therapeutic potential of Dl-3-n-butylphthalide in NTG-induced migraine mouse: activating the Nrf2 pathway to alleviate oxidative stress and neuroinflammation
Unveiling the therapeutic potential of Dl-3-n-butylphthalide in NTG-induced migraine mouse: activating the Nrf2 pathway to alleviate oxidative stress and neuroinflammation
Migraine stands as a prevalent primary headache disorder, with prior research highlighting the significant involvement of ...
Increased CX3CL1 in cerebrospinal fluid and ictal serum t-tau elevations in migraine: results from a cross-sectional exploratory case-control study
Increased CX3CL1 in cerebrospinal fluid and ictal serum t-tau elevations in migraine: results from a cross-sectional exploratory case-control study
To date, migraine is diagnosed exclusively based on clinical criteria, but fluid biomarkers are desirable to gain insight ...
Structural equation modeling for identifying the drivers of health-related quality of life improvement experienced by patients with migraine receiving eptinezumab
Structural equation modeling for identifying the drivers of health-related quality of life improvement experienced by patients with migraine receiving eptinezumab
As new migraine therapies emerge, it is crucial for measures to capture the complexities of health-related quality of life...
Frequency and predictors of headache in the first 12 months after traumatic brain injury: results from CENTER-TBI
Frequency and predictors of headache in the first 12 months after traumatic brain injury: results from CENTER-TBI
Headache is a prevalent and debilitating symptom following traumatic brain injury (TBI). Large-scale, prospective cohort s...
Long-term treatment with lasmiditan in patients with migraine: post hoc analysis of treatment patterns and outcomes from the open-label extension of the CENTURION randomized trial
Long-term treatment with lasmiditan in patients with migraine: post hoc analysis of treatment patterns and outcomes from the open-label extension of the CENTURION randomized trial
The objective of this analysis was to gain new insights into the patient characteristics and other factors associated with...
The burden of headache disorders in North India: methodology, and validation of a Hindi version of the HARDSHIP questionnaire, for a community-based survey in Delhi and national capital territory region
The burden of headache disorders in North India: methodology, and validation of a Hindi version of the HARDSHIP questionnaire, for a community-based survey in Delhi and national capital territory region
Knowledge of the prevalence and attributable burden of headache disorders in India is sparse, with only two recent populat...
Specific cognitive and psychological alterations are more strongly linked to increased migraine disability than chronic migraine diagnosis
Specific cognitive and psychological alterations are more strongly linked to increased migraine disability than chronic migraine diagnosis
The efficiency of The International Classification of Headache Disorders (ICHD-3) in reflecting patients’ disability...
Is erenumab an efficient alternative for the prevention of episodic and chronic migraine in Spain? Results of a cost-effectiveness analysis
Is erenumab an efficient alternative for the prevention of episodic and chronic migraine in Spain? Results of a cost-effectiveness analysis
The reimbursement of erenumab in Spain and other European countries is currently restricted because of the cost of this no...
Societal and economic burden of migraine in Spain: results from the 2020 National Health and Wellness Survey
Societal and economic burden of migraine in Spain: results from the 2020 National Health and Wellness Survey
The burden of migraine goes beyond the pain and associated symptoms. We aimed to describe the impact of migraine in health...
CGRP-monoclonal antibodies in Japan: insights from an online survey of physician members of the Japanese headache society
CGRP-monoclonal antibodies in Japan: insights from an online survey of physician members of the Japanese headache society
Anti-calcitonin gene-related peptide monoclonal antibodies (CGRPmAbs) have greatly changed migraine treatment options. In ...
Calcitonin receptor, calcitonin gene-related peptide and amylin distribution in C1/2 dorsal root ganglia
Calcitonin receptor, calcitonin gene-related peptide and amylin distribution in C1/2 dorsal root ganglia
The upper cervical dorsal root ganglia (DRG) are important for the transmission of sensory information associated with the...
Safety and tolerability of atogepant for the preventive treatment of migraine: a post hoc analysis of pooled data from four clinical trials
Safety and tolerability of atogepant for the preventive treatment of migraine: a post hoc analysis of pooled data from four clinical trials
Conventional, non-specific preventive migraine treatments often demonstrate low rates of treatment persistence due to poor...
Decoding pain through facial expressions: a study of patients with migraine
Decoding pain through facial expressions: a study of patients with migraine
The present study used the Facial Action Coding System (FACS) to analyse changes in facial activities in individuals with ...
The glymphatic system in migraine and other headaches
The glymphatic system in migraine and other headaches
Glymphatic system is an emerging pathway of removing metabolic waste products and toxic solutes from the brain tissue. It ...
AMPK activation attenuates central sensitization in a recurrent nitroglycerin-induced chronic migraine mouse model by promoting microglial M2-type polarization
AMPK activation attenuates central sensitization in a recurrent nitroglycerin-induced chronic migraine mouse model by promoting microglial M2-type polarization
Energy metabolism disorders and neurogenic inflammation play important roles in the central sensitization to chronic migra...
The crucial role of locus coeruleus noradrenergic neurons in the interaction between acute sleep disturbance and headache
The crucial role of locus coeruleus noradrenergic neurons in the interaction between acute sleep disturbance and headache
Both epidemiological and clinical studies have indicated that headache and sleep disturbances share a complex relationship...
LncRNA Anxa10-203 enhances Mc1r mRNA stability to promote neuropathic pain by recruiting DHX30 in the trigeminal ganglion
LncRNA Anxa10-203 enhances Mc1r mRNA stability to promote neuropathic pain by recruiting DHX30 in the trigeminal ganglion
Trigeminal nerve injury is one of the most serious complications in oral clinics, and the subsequent chronic orofacial pai...
The impact of primary headaches on disability outcomes: a literature review and meta-analysis to inform future iterations of the Global Burden of Disease study
The impact of primary headaches on disability outcomes: a literature review and meta-analysis to inform future iterations of the Global Burden of Disease study
The burden and disability associated with headaches are conceptualized and measured differently at patients’ and pop...
Harris Poll Migraine Report Card: population-based examination of high-frequency headache/migraine and acute medication overuse
Harris Poll Migraine Report Card: population-based examination of high-frequency headache/migraine and acute medication overuse
Migraine is a disabling neurologic disease that can fluctuate over time in severity, frequency, and acute medication use. ...
Associations of combined lifestyle index with migraine prevalence and headache frequency: a cross-sectional study from the MECH-HK study
Associations of combined lifestyle index with migraine prevalence and headache frequency: a cross-sectional study from the MECH-HK study
Prior research has shown that individual lifestyles were associated with migraine. Yet, few studies focused on combined li...
Postdromal symptoms in migraine: a REFORM study
Postdromal symptoms in migraine: a REFORM study
Migraine is a multiphasic neurovascular disorder, where headache can be succeeded by postdromal symptoms. However, there a...
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