SCI时时刷

search
+
Efficacy and safety of atogepant, a small molecule CGRP receptor antagonist, for the preventive treatment of migraine: a systematic review and meta-analysis
Efficacy and safety of atogepant, a small molecule CGRP receptor antagonist, for the preventive treatment of migraine: a systematic review and meta-analysis
Migraine is one of the most common diseases worldwide while current treatment options are not ideal. New therapeutic class...
Children and adolescents with primary headaches exhibit altered sensory profiles – a multi-modal investigation
Children and adolescents with primary headaches exhibit altered sensory profiles – a multi-modal investigation
Pediatric headache is an increasing medical problem that has adverse effects on children’s quality of life, academic...
Glucagon-like peptide-1 (GLP-1) receptor agonists for headache and pain disorders: a systematic review
Glucagon-like peptide-1 (GLP-1) receptor agonists for headache and pain disorders: a systematic review
Glucagon-like peptide-1 (GLP-1) plays a crucial role in metabolic disorders by enhancing insulin secretion, inhibiting glu...
Inhibition of 2-AG hydrolysis alleviates posttraumatic headache attributed to mild traumatic brain injury
Inhibition of 2-AG hydrolysis alleviates posttraumatic headache attributed to mild traumatic brain injury
Posttraumatic headache (PTH) is a common and debilitating symptom following repetitive mild traumatic brain injury (rmTBI)...
Inflammatory response of leptomeninges to a single cortical spreading depolarization
Inflammatory response of leptomeninges to a single cortical spreading depolarization
Neurogenic meningeal inflammation is regarded as a key driver of migraine headache. Multiple evidence show importance of i...
Imbalanced temporal states of cortical blood-oxygen-level-dependent signal variability during rest in episodic migraine
Imbalanced temporal states of cortical blood-oxygen-level-dependent signal variability during rest in episodic migraine
Migraine has been associated with functional brain changes including altered connectivity and activity both during and bet...
The burden of headache and a health-care needs assessment in the adult population of Mali: a cross-sectional population-based study
The burden of headache and a health-care needs assessment in the adult population of Mali: a cross-sectional population-based study
Our recent studies have shown headache disorders to be very common in the central and western sub-Saharan countries of Ben...
Clinical profile and treatment outcomes of idiopathic intracranial hypertension: a multicenter study from Korea
Clinical profile and treatment outcomes of idiopathic intracranial hypertension: a multicenter study from Korea
Currently, there is a relative lack of detailed reports regarding clinical presentation and outcome of idiopathic intracra...
Exploring potential neuroimaging biomarkers for the response to non-steroidal anti-inflammatory drugs in episodic migraine
Exploring potential neuroimaging biomarkers for the response to non-steroidal anti-inflammatory drugs in episodic migraine
Non-steroidal anti-inflammatory drugs (NSAIDs) are considered first-line medications for acute migraine attacks. However, ...
Provocation of attacks to discover migraine signaling mechanisms and new drug targets: early history and future perspectives - a narrative review
Provocation of attacks to discover migraine signaling mechanisms and new drug targets: early history and future perspectives - a narrative review
The development of several experimental migraine provocation models has significantly contributed to an understanding of t...
Hypersensitivity to BKCa channel opening in persistent post-traumatic headache
Hypersensitivity to BKCa channel opening in persistent post-traumatic headache
Large conductance  calcium-activated potassium (BKCa) channels have been implicated in the neurobiological underp...
Connectivity of the insular subdivisions differentiates posttraumatic headache-associated from nonheadache-associated mild traumatic brain injury: an arterial spin labelling study
Connectivity of the insular subdivisions differentiates posttraumatic headache-associated from nonheadache-associated mild traumatic brain injury: an arterial spin labelling study
The insula is an important part of the posttraumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) neuro...
Occurrence of new or more severe headaches following COVID-19 is associated with markers of microglial activation and peripheral sensitization: results from a prospective cohort study
Occurrence of new or more severe headaches following COVID-19 is associated with markers of microglial activation and peripheral sensitization: results from a prospective cohort study
New onset or worsening of a headache disorder substantially contributes to the disease burden of post-COVID-19. Its manage...
Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization
Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization
Currently, the treatment and prevention of migraine remain highly challenging. Mendelian randomization (MR) has been widel...
Shifts in structural connectome organization in the limbic and sensory systems of patients with episodic migraine
Shifts in structural connectome organization in the limbic and sensory systems of patients with episodic migraine
Migraine is a complex neurological condition characterized by recurrent headaches, which is often accompanied by various n...
Longitudinal neurofunctional changes in medication overuse headache patients after mindfulness practice in a randomized controlled trial (the MIND-CM study)
Longitudinal neurofunctional changes in medication overuse headache patients after mindfulness practice in a randomized controlled trial (the MIND-CM study)
Mindfulness practice has gained interest in the management of Chronic Migraine associated with Medication Overuse Headache...
PACAP-38 and sex hormones in women with migraine: exploratory analysis of a cross-sectional, matched cohort study
PACAP-38 and sex hormones in women with migraine: exploratory analysis of a cross-sectional, matched cohort study
Endogeneous and exogeneous sex hormones can impact the frequency and severity of migraine attacks, but the underlying mech...
Global, regional, and national burden and trends of migraine among women of childbearing age from 1990 to 2021: insights from the Global Burden of Disease Study 2021
Global, regional, and national burden and trends of migraine among women of childbearing age from 1990 to 2021: insights from the Global Burden of Disease Study 2021
Migraine, a neurological disorder with a significant female predilection, is the leading cause of disability-adjusted life...
Altered immunity in migraine: a comprehensive scoping review
Altered immunity in migraine: a comprehensive scoping review
The pathogenesis of migraine remains unclear; however, a large body of evidence supports the hypothesis that immunological...
Therapeutic patterns and migraine disease burden in switchers of CGRP-targeted monoclonal antibodies – insights from the German NeuroTransData registry
Therapeutic patterns and migraine disease burden in switchers of CGRP-targeted monoclonal antibodies – insights from the German NeuroTransData registry
Monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP) pathway have shown good efficacy in migr...
Plasma calcitonin gene-related peptide levels in idiopathic intracranial hypertension: an exploratory study
Plasma calcitonin gene-related peptide levels in idiopathic intracranial hypertension: an exploratory study
Idiopathic intracranial hypertension (IIH) is a debilitating condition characterized by increased intracranial pressure of...
A cross-tissue transcriptome-wide association study reveals novel susceptibility genes for migraine
A cross-tissue transcriptome-wide association study reveals novel susceptibility genes for migraine
Migraine is a common neurological disorder with a strong genetic component. Despite the identification of over 100 loci as...
Genetic evidence for the causal relationships between migraine, dementia, and longitudinal brain atrophy
Genetic evidence for the causal relationships between migraine, dementia, and longitudinal brain atrophy
Migraine is a neurological disease with a significant genetic component and is characterized by recurrent and prolonged ep...
Medication-overuse headache: a narrative review
Medication-overuse headache: a narrative review
Medication-overuse headache (MOH), which potentially involves 1–2% of the population, is defined as a headache, on &...
Brain structural and functional abnormalities associated with acute post-traumatic headache: iron deposition and functional connectivity
Brain structural and functional abnormalities associated with acute post-traumatic headache: iron deposition and functional connectivity
The purpose of this study was to interrogate brain iron accumulation in participants with acute post-traumatic headache (P...
PACAP38/mast-cell-specific receptor axis mediates repetitive stress-induced headache in mice
PACAP38/mast-cell-specific receptor axis mediates repetitive stress-induced headache in mice
Pain, an evolutionarily conserved warning system, lets us recognize threats and motivates us to adapt to those threats. He...
MERTK in the rat trigeminal system: a potential novel target for cluster headache?
MERTK in the rat trigeminal system: a potential novel target for cluster headache?
The trigeminal system is key to the pathophysiology of migraine and cluster headache, two primary headache disorders that ...
Aberrant cerebral blood flow and functional connectivity in patients with vestibular migraine: a resting-state ASL and fMRI study
Aberrant cerebral blood flow and functional connectivity in patients with vestibular migraine: a resting-state ASL and fMRI study
Prior neuroimaging studies on vestibular migraine (VM) have extensively certified the functional and structural alteration...
Sustained response to atogepant in episodic migraine: post hoc analyses of a 12-week randomized trial and a 52-week long-term safety trial
Sustained response to atogepant in episodic migraine: post hoc analyses of a 12-week randomized trial and a 52-week long-term safety trial
Atogepant is an oral calcitonin gene–related peptide receptor antagonist approved for the preventive treatment of mi...
Poor healthy lifestyle and life’s essential 8 are associated with higher risk of new-onset migraine: a prospective cohort study
Poor healthy lifestyle and life’s essential 8 are associated with higher risk of new-onset migraine: a prospective cohort study
Lifestyle are closely related to migraine. However, there is a lack of studies investigating the association between Healt...
阅读更多
format_indent_increase