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Comorbidities and mortality risk in adults younger than 50 years of age with chronic obstructive pulmonary disease
Comorbidities and mortality risk in adults younger than 50 years of age with chronic obstructive pulmonary disease
Patients with chronic obstructive pulmonary disease (COPD), usually diagnosed after the 6th decade, frequently suffer from...
Chronic air pollution-induced subclinical airway inflammation and polygenic susceptibility
Chronic air pollution-induced subclinical airway inflammation and polygenic susceptibility
Air pollutants can activate low-grade subclinical inflammation which further impairs respiratory health. We aimed to inves...
One-minute sit-to-stand test is practical to assess and follow the muscle weakness in cystic fibrosis
One-minute sit-to-stand test is practical to assess and follow the muscle weakness in cystic fibrosis
Quadriceps muscle weakness and reduced exercise tolerance are prevalent and associated with a worse prognosis in patients ...
Long-term comprehensive cardiopulmonary phenotyping of COVID-19
Long-term comprehensive cardiopulmonary phenotyping of COVID-19
Persistent symptoms after initial COVID-19 infection are common and are frequently referred to by the umbrella terms ̶...
Long-term variability of impulse oscillometry and spirometry in stable COPD and asthma
Long-term variability of impulse oscillometry and spirometry in stable COPD and asthma
While optimizing spirometry is a challenge for lung function labs, long-term variability if any between IOS (impulse oscil...
DNA-PKcs participated in hypoxic pulmonary hypertension
DNA-PKcs participated in hypoxic pulmonary hypertension
Hypoxic pulmonary hypertension (HPH) is a common complication of chronic lung disease, which severely affects the survival...
A prediction model for hospital mortality in patients with severe community-acquired pneumonia and chronic obstructive pulmonary disease
A prediction model for hospital mortality in patients with severe community-acquired pneumonia and chronic obstructive pulmonary disease
No personalized prediction model or standardized algorithm exists to identify those at high risk of death among severe com...
Hierarchical clock-scale hand-drawn mapping as a simple method for bronchoscopic navigation in peripheral pulmonary nodule
Hierarchical clock-scale hand-drawn mapping as a simple method for bronchoscopic navigation in peripheral pulmonary nodule
A feasible and economical bronchoscopic navigation method in guiding peripheral pulmonary nodule biopsy is lacking. To inv...
Propylene glycol, a component of electronic cigarette liquid, damages epithelial cells in human small airways
Propylene glycol, a component of electronic cigarette liquid, damages epithelial cells in human small airways
Electronic cigarettes (e-cigarettes) are used worldwide as a substitute for conventional cigarettes. Although they are pri...
The sialidase NEU3 promotes pulmonary fibrosis in mice
The sialidase NEU3 promotes pulmonary fibrosis in mice
Sialic acid is often the distal sugar on glycoconjugates, and sialidases are enzymes that remove this sugar. In fibrotic l...
The respiratory microbiota alpha-diversity in chronic lung diseases: first systematic review and meta-analysis
The respiratory microbiota alpha-diversity in chronic lung diseases: first systematic review and meta-analysis
While there seems to be a consensus that a decrease in gut microbiome diversity is related to a decline in health status, ...
Correction to: Shp2 positively regulates cigarette smoke-induced epithelial mesenchymal transition by mediating MMP-9 production
Correction to: Shp2 positively regulates cigarette smoke-induced epithelial mesenchymal transition by mediating MMP-9 production
Following publication of the original article [1], the authors identified an error in Fig. 6B. During the preparation of t...
Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway
Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway
Pulmonary hypertension (PH) is a progressive and fatal cardiopulmonary disease characterized by pulmonary vascular remodel...
ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10
ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10
Silicosis is a pulmonary fibrosis-associated disease caused by the inhalation of large amounts of free silicon dioxide (Si...
NHLRC2 expression is increased in idiopathic pulmonary fibrosis
NHLRC2 expression is increased in idiopathic pulmonary fibrosis
Variants of NHL repeat-containing protein 2 (NHLRC2) have been associated with severe fibrotic interstitial lung disease i...
Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury
Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury
Bronchopulmonary dysplasia (BPD) is a chronic lung disease in premature infants that may cause long-term lung dysfunction....
Dynamic early warning scores for predicting clinical deterioration in patients with respiratory disease
Dynamic early warning scores for predicting clinical deterioration in patients with respiratory disease
The National Early Warning Score-2 (NEWS-2) is used to detect patient deterioration in UK hospitals but fails to take acco...
Decreased humoral immune response in the bronchi of rapid decliners with chronic obstructive pulmonary disease
Decreased humoral immune response in the bronchi of rapid decliners with chronic obstructive pulmonary disease
Identification of COPD patients with a rapid decline in FEV1 is of particular interest for prognostic and therapeutic reas...
Mechanosensitive Piezo channels mediate the physiological and pathophysiological changes in the respiratory system
Mechanosensitive Piezo channels mediate the physiological and pathophysiological changes in the respiratory system
Mechanosensitive Piezo ion channels were first reported in 2010 in a mouse neuroblastoma cell line, opening up a new field...