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Blood lipid profiles as a prognostic biomarker in idiopathic pulmonary fibrosis
Blood lipid profiles as a prognostic biomarker in idiopathic pulmonary fibrosis
Dysregulation of lipid metabolism is implicated in the pathogenesis of idiopathic pulmonary fibrosis (IPF). However, the a...
Regulation of myofibroblast dedifferentiation in pulmonary fibrosis
Regulation of myofibroblast dedifferentiation in pulmonary fibrosis
Idiopathic pulmonary fibrosis is a lethal, progressive, and irreversible condition that has become a significant focus of ...
Phenotypical characteristics of nontuberculous mycobacterial infection in patients with bronchiectasis
Phenotypical characteristics of nontuberculous mycobacterial infection in patients with bronchiectasis
The global mortality and morbidity rates of bronchiectasis patients due to nontuberculous mycobacteria (NTM) pulmonary inf...
Altered hypoxia-induced cellular responses and inflammatory profile in lung fibroblasts from COPD patients compared to control subjects
Altered hypoxia-induced cellular responses and inflammatory profile in lung fibroblasts from COPD patients compared to control subjects
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by chronic bronchitis, emphysema and...
Inhalation of hydrogen gas protects against mitomycin-induced pulmonary veno-occlusive disease
Inhalation of hydrogen gas protects against mitomycin-induced pulmonary veno-occlusive disease
As a subtype of pulmonary hypertension (PH), pulmonary veno-occlusive disease (PVOD) is devastating and life-threatening d...
Low dose of morphine to relieve dyspnea in acute respiratory failure: the OpiDys double-blind randomized controlled trial
Low dose of morphine to relieve dyspnea in acute respiratory failure: the OpiDys double-blind randomized controlled trial
Morphine relieves dyspnea in various clinical circumstances. Whether or not this applies to patients admitted to intensive...
Microbiological characteristics of the lower airway in adults with bronchiectasis: a prospective cohort study
Microbiological characteristics of the lower airway in adults with bronchiectasis: a prospective cohort study
Microbial infection and colonization are frequently associated with disease progression and poor clinical outcomes in bron...
Demographic and geographical trends in chronic lower respiratory diseases mortality in the United States, 1999 to 2020
Demographic and geographical trends in chronic lower respiratory diseases mortality in the United States, 1999 to 2020
Chronic lower respiratory disease (CLRD) related mortality has decreased in the United States due to increasing awareness ...
Risk of lung disease in the PI*SS genotype of alpha-1 antitrypsin: an EARCO research project
Risk of lung disease in the PI*SS genotype of alpha-1 antitrypsin: an EARCO research project
The PI*S variant is one of the most prevalent mutations within alpha-1 antitrypsin deficiency (AATD). The risk of developi...
Correlation between immune-related adverse events and efficacy of PD-(L)1 inhibitors in small cell lung cancer: a multi-center retrospective study
Correlation between immune-related adverse events and efficacy of PD-(L)1 inhibitors in small cell lung cancer: a multi-center retrospective study
Patients receiving PD-(L)1 inhibitors frequently encounter unusual side effects known as immune-related adverse events (ir...
The impact of antifibrotic use on long-term clinical outcomes in the pulmonary fibrosis foundation registry
The impact of antifibrotic use on long-term clinical outcomes in the pulmonary fibrosis foundation registry
Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease (ILD) with a high mortality rate. The antif...
Longitudinal metabolomics of human plasma reveal metabolic dynamics and predictive markers of antituberculosis drug-induced liver injury
Longitudinal metabolomics of human plasma reveal metabolic dynamics and predictive markers of antituberculosis drug-induced liver injury
Tuberculosis (TB) remains the second leading cause of death from a single infectious agent and long-term medication could ...
Deregulated immune cell recruitment orchestrated by c-MET impairs pulmonary inflammation and fibrosis
Deregulated immune cell recruitment orchestrated by c-MET impairs pulmonary inflammation and fibrosis
Pulmonary fibrosis (PF) represents the pathologic end stage of several interstitial lung diseases (ILDs) associated with h...
Radiomics based on HRCT can predict RP-ILD and mortality in anti-MDA5 + dermatomyositis patients: a multi-center retrospective study
Radiomics based on HRCT can predict RP-ILD and mortality in anti-MDA5 + dermatomyositis patients: a multi-center retrospective study
To assess the effectiveness of HRCT-based radiomics in predicting rapidly progressive interstitial lung disease (RP-ILD) a...
Chronic obstructive pulmonary disease affects outcome in surgical patients with perioperative organ injury: a retrospective cohort study in Germany
Chronic obstructive pulmonary disease affects outcome in surgical patients with perioperative organ injury: a retrospective cohort study in Germany
The impact of chronic obstructive pulmonary disease (COPD) on outcome in perioperative organ injury (POI) has not yet been...
A single-center, retrospective study of hospitalized patients with lower respiratory tract infections: clinical assessment of metagenomic next-generation sequencing and identification of risk factors in patients
A single-center, retrospective study of hospitalized patients with lower respiratory tract infections: clinical assessment of metagenomic next-generation sequencing and identification of risk factors in patients
Lower respiratory tract infections(LRTIs) in adults are complicated by diverse pathogens that challenge traditional detect...
Tumor mutational burden adjusted by neutrophil-to-lymphocyte ratio serves as a potential biomarker for atezolizumab-treated patients with extensive stage small cell lung cancer
Tumor mutational burden adjusted by neutrophil-to-lymphocyte ratio serves as a potential biomarker for atezolizumab-treated patients with extensive stage small cell lung cancer
There is a desperate for the identification of more accurate and efficient biomarkers for ICI responses in patients with S...
Treating sleep-disordered breathing of idiopathic pulmonary fibrosis patients with CPAP and nocturnal oxygen treatment. A pilot study
Treating sleep-disordered breathing of idiopathic pulmonary fibrosis patients with CPAP and nocturnal oxygen treatment. A pilot study
Sleep-disordered breathing (SDB) is a major comorbidity in idiopathic pulmonary fibrosis (IPF) and is associated with a po...
An explainable machine learning-based model to predict intensive care unit admission among patients with community-acquired pneumonia and connective tissue disease
An explainable machine learning-based model to predict intensive care unit admission among patients with community-acquired pneumonia and connective tissue disease
There is no individualized prediction model for intensive care unit (ICU) admission on patients with community-acquired pn...
Delineating excess comorbidities in idiopathic pulmonary fibrosis: an observational study
Delineating excess comorbidities in idiopathic pulmonary fibrosis: an observational study
Our study examined whether prevalent and incident comorbidities are increased in idiopathic pulmonary fibrosis (IPF) patie...
Effectiveness of pulmonary rehabilitation programmes and/or respiratory muscle training in patients with post-COVID conditions: a systematic review
Effectiveness of pulmonary rehabilitation programmes and/or respiratory muscle training in patients with post-COVID conditions: a systematic review
The term “post-COVID-19 condition” refers to the symptomatology that appears between four to twelve weeks afte...
Outcomes of different pulmonary rehabilitation protocols in patients under mechanical ventilation with difficult weaning: a retrospective cohort study
Outcomes of different pulmonary rehabilitation protocols in patients under mechanical ventilation with difficult weaning: a retrospective cohort study
The endeavor of liberating patients from ventilator dependence within respiratory care centers (RCCs) poses considerable c...
Prognostic biomarker tumor-infiltrating lymphocytes failed to serve as a predictive biomarker for postoperative radiotherapy in completely resected pN2 non-small cell lung cancer: a retrospective analysis
Prognostic biomarker tumor-infiltrating lymphocytes failed to serve as a predictive biomarker for postoperative radiotherapy in completely resected pN2 non-small cell lung cancer: a retrospective analysis
Evidence suggests that radiotherapy is a potent immunomodulator in non-small cell lung cancer (NSCLC). Conversely, it has ...
IPF-related new macrophage subpopulations and diagnostic biomarker identification - combine machine learning with single-cell analysis
IPF-related new macrophage subpopulations and diagnostic biomarker identification - combine machine learning with single-cell analysis
Idiopathic pulmonary fibrosis (IPF) is a chronic disease of unknown etiology that lacks a specific treatment. In IPF, macr...
Trigonelline hydrochloride attenuates silica-induced pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation
Trigonelline hydrochloride attenuates silica-induced pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation
Silicosis represents a paramount occupational health hazard globally, with its incidence, morbidity, and mortality on an u...
Dynamics of pulmonary mucosal cytotoxic CD8 T-cells in people living with HIV under suppressive antiretroviral therapy
Dynamics of pulmonary mucosal cytotoxic CD8 T-cells in people living with HIV under suppressive antiretroviral therapy
Despite the success of antiretroviral therapy (ART), people living with HIV (PLWH) suffer from a high burden of pulmonary ...
Clinical, radiological and histopathological features of patients with familial pulmonary fibrosis
Clinical, radiological and histopathological features of patients with familial pulmonary fibrosis
In familial pulmonary fibrosis (FPF) at least two biological relatives are affected. Patients with FPF have diverse clinic...
TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinoma
TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinoma
TMPRSS2, a key molecule for SARS-CoV-2 invading human host cells, has an association with cancer. However, its association...
Novel insights into the potential applications of stem cells in pulmonary hypertension therapy
Novel insights into the potential applications of stem cells in pulmonary hypertension therapy
Pulmonary hypertension (PH) refers to a group of deadly lung diseases characterized by vascular lesions in the microvascul...
Systemic antibiotics for Pseudomonas aeruginosa infection in outpatients with non-hospitalised exacerbations of pre-existing lung diseases: a randomised clinical trial
Systemic antibiotics for Pseudomonas aeruginosa infection in outpatients with non-hospitalised exacerbations of pre-existing lung diseases: a randomised clinical trial
The effect of dual systemic antibiotic therapy against Pseudomonas aeruginosa in patients with pre-existing lung disease i...
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