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Mortality after treatment of malignant pleural effusions with indwelling pleural catheters versus chemical pleurodesis: a population-based study
Mortality after treatment of malignant pleural effusions with indwelling pleural catheters versus chemical pleurodesis: a population-based study
Little is known about patient outcomes following treatment of malignant pleural effusions (MPE) in the real-world setting....
Euphorbium compositum SN improves the innate defenses of the airway mucosal barrier network during rhinovirus infection
Euphorbium compositum SN improves the innate defenses of the airway mucosal barrier network during rhinovirus infection
Rhinoviruses (RV) are the major cause of common colds in healthy individuals and are associated with acute exacerbations i...
Lactate activates ER stress to promote alveolar epithelial cells apoptosis in pulmonary fibrosis
Lactate activates ER stress to promote alveolar epithelial cells apoptosis in pulmonary fibrosis
Pulmonary fibrosis (PF) is a chronic, progressive lung disease characterized by fibroblast proliferation, extensive extrac...
Computed tomography morphological assessments of central airways in interstitial lung abnormalities and idiopathic pulmonary fibrosis
Computed tomography morphological assessments of central airways in interstitial lung abnormalities and idiopathic pulmonary fibrosis
Little is known about whether central airway morphological changes beyond traction bronchiectasis develop and affect clini...
Atomized inhalation of indocyanine green in thoracoscopic surgery for intralobar pulmonary sequestration: a multicenter study
Atomized inhalation of indocyanine green in thoracoscopic surgery for intralobar pulmonary sequestration: a multicenter study
Investigate the safety and efficacy of preoperative atomization inhalation of indocyanine green (ICG) solution in precise ...
Repeated inhalation of GM-CSF by nonhuman primates induces bronchus-associated lymphoid tissue along the lower respiratory tract
Repeated inhalation of GM-CSF by nonhuman primates induces bronchus-associated lymphoid tissue along the lower respiratory tract
Repeated inhalation of granulocyte-macrophage colony-stimulating factor (GM-CSF) was recently approved in Japan as a treat...
Serum soluble isoform of receptor for advanced glycation end product is a predictive biomarker for acute exacerbation of idiopathic pulmonary fibrosis: a German and Japanese cohort study
Serum soluble isoform of receptor for advanced glycation end product is a predictive biomarker for acute exacerbation of idiopathic pulmonary fibrosis: a German and Japanese cohort study
The receptor for advanced glycation end product (RAGE) is a transmembrane receptor accelerating a pro-inflammatory signal....
Clinical and biologic profiles of patients with acute respiratory distress syndrome by prevalence of chronic obstructive pulmonary disease or emphysema; a cohort study
Clinical and biologic profiles of patients with acute respiratory distress syndrome by prevalence of chronic obstructive pulmonary disease or emphysema; a cohort study
Acute respiratory distress syndrome (ARDS) is characterized by diffuse lung injury. The impact of pre-existing chronic obs...
Activation of LXR signaling ameliorates apoptosis of alveolar epithelial cells in Bronchopulmonary dysplasia
Activation of LXR signaling ameliorates apoptosis of alveolar epithelial cells in Bronchopulmonary dysplasia
Liver X receptors (LXRs) are specialized nuclear receptors essential for maintaining cholesterol homeostasis, modulating L...
Research progress of mitochondrial dysfunction induced pyroptosis in acute lung injury
Research progress of mitochondrial dysfunction induced pyroptosis in acute lung injury
Acute lung injury (ALI) is a common critical respiratory disease in clinical practice, especially in the ICU, with a high ...
Ivacaftor ameliorates mucus burden, bacterial load, and inflammation in acute but not chronic P. aeruginosa infection in hG551D rats
Ivacaftor ameliorates mucus burden, bacterial load, and inflammation in acute but not chronic P. aeruginosa infection in hG551D rats
Newly approved highly effective modulation therapies (HEMT) have been life-changing for people with CF. Although these dru...
Six clinical phenotypes with prognostic implications were identified by unsupervised machine learning in children and adolescents with SARS-CoV-2 infection: results from a German nationwide registry
Six clinical phenotypes with prognostic implications were identified by unsupervised machine learning in children and adolescents with SARS-CoV-2 infection: results from a German nationwide registry
Phenotypes are important for patient classification, disease prognostication, and treatment customization. We aimed to ide...
Shenqifuzheng injection inhibits lactic acid-induced cisplatin resistance in NSCLC by affecting FBXO22/p53 axis through FOXO3
Shenqifuzheng injection inhibits lactic acid-induced cisplatin resistance in NSCLC by affecting FBXO22/p53 axis through FOXO3
FOXO3 was decreased, while LA and FBXO22 were increased in NSCLC patients. LA promoted cisplatin resistance in NSCLC in vi...
Patient-centered care in pulmonary fibrosis: access, anticipate, and act
Patient-centered care in pulmonary fibrosis: access, anticipate, and act
Comprehensive care integrates individual patient needs and is highly valued for patients with pulmonary fibrosis (PF). The...
Quantitative texture analysis using machine learning for predicting interpretable pulmonary perfusion from non-contrast computed tomography in pulmonary embolism patients
Quantitative texture analysis using machine learning for predicting interpretable pulmonary perfusion from non-contrast computed tomography in pulmonary embolism patients
Pulmonary embolism (PE) is life-threatening and requires timely and accurate diagnosis, yet current imaging methods, like ...
GSK3179106 ameliorates lipopolysaccharide-induced inflammation and acute lung injury by targeting P38 MAPK
GSK3179106 ameliorates lipopolysaccharide-induced inflammation and acute lung injury by targeting P38 MAPK
Acute lung injury (ALI) is a serious acute respiratory disease that can cause alveolar-capillary barrier disruption and pu...
Kiss1 receptor knockout exacerbates airway hyperresponsiveness and remodeling in a mouse model of allergic asthma
Kiss1 receptor knockout exacerbates airway hyperresponsiveness and remodeling in a mouse model of allergic asthma
In asthma, sex-steroids signaling is recognized as a critical regulator of disease pathophysiology. However, the paradoxic...
Impact of HHIP gene polymorphisms on phenotypes, serum IL-17 and IL-18 in COPD patients of the Chinese Han population
Impact of HHIP gene polymorphisms on phenotypes, serum IL-17 and IL-18 in COPD patients of the Chinese Han population
Genetic factors, including the Hedgehog Interacting Protein (HHIP) gene, play a crucial role in Chronic Obstructive Pulmon...
A novel Non-rodent animal model of hydrochloric acid-induced acute and chronic lung injury
A novel Non-rodent animal model of hydrochloric acid-induced acute and chronic lung injury
Hydrochloric acid is one of the most prevalent and hazardous chemicals. Accidental spills occur in industrial plants or du...
Plasma genome-wide mendelian randomization identifies potentially causal genes in idiopathic pulmonary fibrosis
Plasma genome-wide mendelian randomization identifies potentially causal genes in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a complex lung disease with a very poor prognosis. Existing drugs for the treatment...
MiR-125b-5p alleviates pulmonary fibrosis by inhibiting TGFβ1-mediated epithelial-mesenchymal transition via targeting BAK1
MiR-125b-5p alleviates pulmonary fibrosis by inhibiting TGFβ1-mediated epithelial-mesenchymal transition via targeting BAK1
This study explores the role and potential mechanisms of microRNA-125b-5p (miR-125b-5p) in pulmonary fibrosis (PF). PF is ...
CHF6523 data suggest that the phosphoinositide 3-kinase delta isoform is not a suitable target for the management of COPD
CHF6523 data suggest that the phosphoinositide 3-kinase delta isoform is not a suitable target for the management of COPD
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition. Given patients with COPD continue to exp...
Can switching from cigarettes to heated tobacco products reduce consequences of pulmonary infection?
Can switching from cigarettes to heated tobacco products reduce consequences of pulmonary infection?
While tobacco industry data suggests that switching from combustible cigarettes to heated tobacco products (HTPs), like IQ...
Effects of inhaled beclometasone dipropionate/formoterol fumarate/glycopyrronium vs. beclometasone dipropionate/formoterol fumarate and placebo on lung hyperinflation and exercise endurance in chronic obstructive pulmonary disease: a randomised controlled trial
Effects of inhaled beclometasone dipropionate/formoterol fumarate/glycopyrronium vs. beclometasone dipropionate/formoterol fumarate and placebo on lung hyperinflation and exercise endurance in chronic obstructive pulmonary disease: a randomised controlled trial
The single-inhaler triple combination of beclometasone dipropionate, formoterol fumarate, and glycopyrronium (BDP/FF/G) is...
MiR-1307-5p enhances fibroblast transdifferentiation to exacerbate chronic obstructive pulmonary disease through regulating FBXL16/HIF1α axis
MiR-1307-5p enhances fibroblast transdifferentiation to exacerbate chronic obstructive pulmonary disease through regulating FBXL16/HIF1α axis
Chronic obstructive pulmonary disease (COPD) is an irreversible and progressive chronic inflammatory lung disease which af...
Benefit of dual bronchodilator therapy on exacerbations in former and current smokers with chronic obstructive pulmonary disease in real-world clinical practice: a multicenter validation study (TOReTO)
Benefit of dual bronchodilator therapy on exacerbations in former and current smokers with chronic obstructive pulmonary disease in real-world clinical practice: a multicenter validation study (TOReTO)
Dual bronchodilator therapy, consisting of a long-acting beta-agonist (LABA) and a long-acting muscarinic antagonist (LAMA...
Effect of different CPAP levels on ultrasound-assessed lung aeration and gas exchange in neonates
Effect of different CPAP levels on ultrasound-assessed lung aeration and gas exchange in neonates
Respiratory distress syndrome (RDS) and transient tachypnoea (TTN) are the two commonest neonatal respiratory disorders. T...
Survival, morbidity, and quality of life in pulmonary arterial hypertension patients: a systematic review of outcomes reported by population-based observational studies
Survival, morbidity, and quality of life in pulmonary arterial hypertension patients: a systematic review of outcomes reported by population-based observational studies
Comprehensive summaries on real-world outcomes in pulmonary arterial hypertension (PAH)—a rare, incurable condition,...
Fisetin reduces ovalbumin-triggered airway remodeling by preventing phenotypic switching of airway smooth muscle cells
Fisetin reduces ovalbumin-triggered airway remodeling by preventing phenotypic switching of airway smooth muscle cells
The transformation of airway smooth muscle cells (ASMCs) from a quiescent phenotype to a hypersecretory and hypercontracti...
Differential transcriptomic host responses in the early phase of viral and bacterial infections in human lung tissue explants ex vivo
Differential transcriptomic host responses in the early phase of viral and bacterial infections in human lung tissue explants ex vivo
The first 24 h of infection represent a critical time window in interactions between pathogens and host tissue. H...
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