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The IL-33:ST2 axis is unlikely to play a central fibrogenic role in idiopathic pulmonary fibrosis
The IL-33:ST2 axis is unlikely to play a central fibrogenic role in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease (ILD) with limited treatment options. Inter...
Particulate matter10-induced airway inflammation and fibrosis can be regulated by chitinase-1 suppression
Particulate matter10-induced airway inflammation and fibrosis can be regulated by chitinase-1 suppression
Particulate matter10 (PM10) can induce airway inflammation and fibrosis. Recently, chitinase-1 has been shown to play key ...
Pseudomonas aeruginosa isolation is an important predictor for recurrent hemoptysis after bronchial artery embolization in patients with idiopathic bronchiectasis: a multicenter cohort study
Pseudomonas aeruginosa isolation is an important predictor for recurrent hemoptysis after bronchial artery embolization in patients with idiopathic bronchiectasis: a multicenter cohort study
Nearly half of bronchiectasis patients receiving bronchial artery embolization (BAE) still have recurrent hemoptysis, whic...
Enhanced immune complex formation in the lungs of patients with dermatomyositis
Enhanced immune complex formation in the lungs of patients with dermatomyositis
Interstitial lung disease is frequently comorbid with dermatomyositis and has a poor prognosis, especially in patients wit...
GlyPerA™ effectively shields airway epithelia from SARS-CoV-2 infection and inflammatory events
GlyPerA™ effectively shields airway epithelia from SARS-CoV-2 infection and inflammatory events
New SARS-CoV-2 variants of concern (VOCs) and waning immunity illustrate that quick and easy-to-use agents are needed to p...
No increased prevalence of autoantibodies neutralizing type I IFNs in idiopathic pulmonary fibrosis patients
No increased prevalence of autoantibodies neutralizing type I IFNs in idiopathic pulmonary fibrosis patients
SARS-CoV2 infection has a poor prognosis in patients affected of idiopathic pulmonary fibrosis (IPF). Autoantibodies (auto...
The emerging role of the piRNA/PIWI complex in respiratory tract diseases
The emerging role of the piRNA/PIWI complex in respiratory tract diseases
PIWI-interacting RNA (piRNA) is a class of recently discovered small non-coding RNA molecules with a length of 18–33...
Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction
Inhibition of fatty acid synthase protects obese mice from acute lung injury via ameliorating lung endothelial dysfunction
Obesity has been identified as a risk factor for acute lung injury/acute respiratory distress syndrome (ALI/ARDS). However...
Dietary patterns, lung function and asthma in childhood: a longitudinal study
Dietary patterns, lung function and asthma in childhood: a longitudinal study
Longitudinal epidemiological data are scarce examining the relationship between dietary patterns and respiratory outcomes ...
Surface electromyography to quantify neuro-respiratory drive and neuro-mechanical coupling in mechanically ventilated children
Surface electromyography to quantify neuro-respiratory drive and neuro-mechanical coupling in mechanically ventilated children
The patient’s neuro-respiratory drive, measured as electrical activity of the diaphragm (EAdi), quantifies the mecha...
Effects of gastroesophageal reflux disease treatment with proton pump inhibitors on the risk of acute exacerbation and pneumonia in patients with COPD
Effects of gastroesophageal reflux disease treatment with proton pump inhibitors on the risk of acute exacerbation and pneumonia in patients with COPD
Gastroesophageal reflux disease (GERD) has been suggested as a risk factor for acute exacerbation of chronic obstructive p...
Proteomics and metabolomics profiling reveal panels of circulating diagnostic biomarkers and molecular subtypes in stable COPD
Proteomics and metabolomics profiling reveal panels of circulating diagnostic biomarkers and molecular subtypes in stable COPD
Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease with high morbidity and mortality, esp...
Weight loss and outcomes in subjects with progressive pulmonary fibrosis: data from the INBUILD trial
Weight loss and outcomes in subjects with progressive pulmonary fibrosis: data from the INBUILD trial
Lower body mass index (BMI) and weight loss have been associated with worse outcomes in some studies in patients with pulm...
Childhood asthma diagnoses declined during the COVID-19 pandemic in the United States
Childhood asthma diagnoses declined during the COVID-19 pandemic in the United States
Prior studies have documented declines in pediatric asthma exacerbations and asthma-related health care utilization during...
National, subnational and risk attributed burden of chronic respiratory diseases in Iran from 1990 to 2019
National, subnational and risk attributed burden of chronic respiratory diseases in Iran from 1990 to 2019
Data on the distribution of the burden of diseases is vital for policymakers for the appropriate allocation of resources. ...
IL-27 induces autophagy through regulation of the DNMT1/lncRNA MEG3/ERK/p38 axis to reduce pulmonary fibrosis
IL-27 induces autophagy through regulation of the DNMT1/lncRNA MEG3/ERK/p38 axis to reduce pulmonary fibrosis
Previous studies have shown that interleukin-27 (IL-27) can reduce bleomycin (BLM)-induced pulmonary fibrosis (PF). Howeve...
Effectiveness and economic impact of Dupilumab in asthma: a population-based cohort study
Effectiveness and economic impact of Dupilumab in asthma: a population-based cohort study
Severe asthma is burdened by relevant socio-economic and clinical impact. Randomized controlled trials on Dupilumab showed...
Exhaled biomarkers in adults with non-productive cough
Exhaled biomarkers in adults with non-productive cough
Chronic cough is a common condition but disease mechanisms are not fully understood. Our aim was to study respiratory biom...
Correction: Reference values of impulse oscillometry (IOS) for healthy Chinese children aged 4–17 years
Correction: Reference values of impulse oscillometry (IOS) for healthy Chinese children aged 4–17 years
Jinhong Wu, Hao Zhang, Yongsheng Shi, Jinrong Wang, Yuling Han, Qiaoling Zhang, Ning Wang, Sha Liu, Yuehua Zhang, Huifen Z...
Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia
Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia
COVID-19 remains a major public health challenge, requiring the development of tools to improve diagnosis and inform thera...
Targeting of G-protein coupled receptor 40 alleviates airway hyperresponsiveness through RhoA/ROCK1 signaling pathway in obese asthmatic mice
Targeting of G-protein coupled receptor 40 alleviates airway hyperresponsiveness through RhoA/ROCK1 signaling pathway in obese asthmatic mice
Obesity increases the severity of airway hyperresponsiveness (AHR) in individuals with asthma, but the mechanism is not we...
A literature review of microRNA and gene signaling pathways involved in the apoptosis pathway of lung cancer
A literature review of microRNA and gene signaling pathways involved in the apoptosis pathway of lung cancer
Lung cancer is one of the leading causes of death in the world and the deadliest of all cancers. Apoptosis is a key pathwa...
Limited effect of reducing pulmonary tuberculosis incidence amid mandatory facial masking for COVID-19
Limited effect of reducing pulmonary tuberculosis incidence amid mandatory facial masking for COVID-19
Although the incidence and mortality rates associated with tuberculosis (TB) have been decreasing in many countries, TB re...
Inhaled prostacyclin therapy in the acute respiratory distress syndrome: a randomized controlled multicenter trial
Inhaled prostacyclin therapy in the acute respiratory distress syndrome: a randomized controlled multicenter trial
Acute respiratory distress syndrome (ARDS) results in significant hypoxia, and ARDS is the central pathology of COVID-19. ...
Correction: Clinical and functional characteristics of individuals with alpha-1 antitrypsin deficiency: EARCO international registry
Correction: Clinical and functional characteristics of individuals with alpha-1 antitrypsin deficiency: EARCO international registry
Pneumology Department, Hospital Universitari Vall d’Hebron; Vall d’Hebron Institut de Recerca (VHIR), Vall d’Hebron Barcel...
Worsening of asthma control after recovery from mild to moderate COVID-19 in patients from Hong Kong
Worsening of asthma control after recovery from mild to moderate COVID-19 in patients from Hong Kong
While there are postulations that asthma is potentially associated with severe coronavirus disease 2019 (COVID-19), there ...
Epithelial senescence in idiopathic pulmonary fibrosis is propagated by small extracellular vesicles
Epithelial senescence in idiopathic pulmonary fibrosis is propagated by small extracellular vesicles
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects 3 million people worldwide. Senescence and smal...
A novel, accurate, and non-invasive liquid biopsy test to measure cellular immune responses as a tool to diagnose early-stage lung cancer: a clinical trials study
A novel, accurate, and non-invasive liquid biopsy test to measure cellular immune responses as a tool to diagnose early-stage lung cancer: a clinical trials study
Lung cancer remains the leading cause of death from cancer, worldwide. Developing early detection diagnostic methods, espe...
Decreased ubiquitin modifying enzyme A20 associated with hyper-responsiveness to ovalbumin challenge following intrauterine growth restriction
Decreased ubiquitin modifying enzyme A20 associated with hyper-responsiveness to ovalbumin challenge following intrauterine growth restriction
Intrauterine growth restriction (IUGR) is strongly correlated with an increased risk of asthma later in life. Farm dust pr...
Interstitial lung abnormalities in a large clinical lung cancer screening cohort: association with mortality and ILD diagnosis
Interstitial lung abnormalities in a large clinical lung cancer screening cohort: association with mortality and ILD diagnosis
Interstitial lung abnormalities (ILA) are CT findings suggestive of interstitial lung disease in individuals without a pri...
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