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Correction to: L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fbrosis patient-derived air–liquid interface (ALI) cultures and organoids: in vitro guided personalized therapy of non-F508del patients
Correction to: L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fbrosis patient-derived air–liquid interface (ALI) cultures and organoids: in vitro guided personalized therapy of non-F508del patients
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Benefit of prompt initiation of single-inhaler fluticasone furoate, umeclidinium, and vilanterol (FF/UMEC/VI) in patients with COPD in England following an exacerbation: a retrospective cohort study
Benefit of prompt initiation of single-inhaler fluticasone furoate, umeclidinium, and vilanterol (FF/UMEC/VI) in patients with COPD in England following an exacerbation: a retrospective cohort study
Triple therapy is recommended for patients with chronic obstructive pulmonary disease (COPD) who remain symptomatic despit...
Mortality and exacerbations associated with Stenotrophomonas maltophilia in chronic obstructive pulmonary disease. A regional cohort study of 22,689 outpatients
Mortality and exacerbations associated with Stenotrophomonas maltophilia in chronic obstructive pulmonary disease. A regional cohort study of 22,689 outpatients
The clinical significance of Stenotrophomonas maltophilia in patients with COPD is poorly understood. We aimed to determin...
Early vvECMO implantation may be associated with lower mortality in ARDS
Early vvECMO implantation may be associated with lower mortality in ARDS
Venovenous extracorporeal membrane oxygenation (vvECMO) is used to treat hypoxia in patients with severe acute respiratory...
Eosinophil extracellular traps in asthma: implications for pathogenesis and therapy
Eosinophil extracellular traps in asthma: implications for pathogenesis and therapy
Asthma is a common, chronic inflammatory disease of the airways that affects millions of people worldwide and is associate...
Staphylococcus aureus enterotoxin A- and B-specific IgE in chronic obstructive pulmonary disease
Staphylococcus aureus enterotoxin A- and B-specific IgE in chronic obstructive pulmonary disease
Sensitization to Staphylococcus aureus enterotoxins A (SEA) and B (SEB) has been associated with asthma severity, exacerba...
Incident low muscle mass is associated with greater lung disease and lower circulating leptin in a tobacco-exposed longitudinal cohort
Incident low muscle mass is associated with greater lung disease and lower circulating leptin in a tobacco-exposed longitudinal cohort
Muscle loss is prevalent in chronic obstructive pulmonary disease (COPD). Prior studies evaluating musculoskeletal dysfunc...
TGFβ1-RCN3-TGFBR1 loop facilitates pulmonary fibrosis by orchestrating fibroblast activation
TGFβ1-RCN3-TGFBR1 loop facilitates pulmonary fibrosis by orchestrating fibroblast activation
Idiopathic pulmonary fibrosis (IPF) bears high mortality due to unclear pathogenesis and limited therapeutic options. Ther...
Predictors of the response to phosphodiesterase-5 inhibitors in pulmonary arterial hypertension: an analysis of the Spanish registry
Predictors of the response to phosphodiesterase-5 inhibitors in pulmonary arterial hypertension: an analysis of the Spanish registry
Achieving and maintaining a low-risk profile is associated with favorable outcome in pulmonary arterial hypertension (PAH)...
Airway inflammatory changes in the lungs of patients with asthma-COPD overlap (ACO): a bronchoscopy endobronchial biopsy study
Airway inflammatory changes in the lungs of patients with asthma-COPD overlap (ACO): a bronchoscopy endobronchial biopsy study
Although asthma and chronic obstructive pulmonary disease (COPD) are two distinct chronic airway inflammatory diseases, th...
A prognostic model for systemic lupus erythematosus-associated pulmonary arterial hypertension: CSTAR-PAH cohort study
A prognostic model for systemic lupus erythematosus-associated pulmonary arterial hypertension: CSTAR-PAH cohort study
Pulmonary arterial hypertension is a major cause of death in systemic lupus erythematosus, but there are no tools speciali...
L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fibrosis patient-derived air–liquid interface (ALI) cultures and organoids: in vitro guided personalized therapy of non-F508del patients
L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fibrosis patient-derived air–liquid interface (ALI) cultures and organoids: in vitro guided personalized therapy of non-F508del patients
Cystic fibrosis (CF) is caused by defects of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR-mod...
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation
Macrophage migration inhibitory factor (MIF) and GTPase dynamin-related protein 1 (Drp1)-dependent aberrant mitochondrial ...
SACE and IL-2R as serum biomarkers for evaluation of multi-organ involvement and prognosis of sarcoidosis
SACE and IL-2R as serum biomarkers for evaluation of multi-organ involvement and prognosis of sarcoidosis
Serum biomarkers in the evaluation of organ involvement and prognostic monitoring of sarcoidosis have not been determined....
Variants in transient receptor potential channels and toll-like receptors modify airway responses to allergen and air pollution: a randomized controlled response human exposure study
Variants in transient receptor potential channels and toll-like receptors modify airway responses to allergen and air pollution: a randomized controlled response human exposure study
Environmental co-exposure to allergen and traffic-related air pollution is common globally and contributes to the exacerba...
Dexmedetomidine alleviates pulmonary fibrosis through the ADORA2B-Mediated MAPK signaling pathway
Dexmedetomidine alleviates pulmonary fibrosis through the ADORA2B-Mediated MAPK signaling pathway
Idiopathic pulmonary fibrosis (IPF) is a chronically progressive fibrotic pulmonary disease characterized by an uncertain ...
Quantifying ventilation by X-ray velocimetry in healthy adults
Quantifying ventilation by X-ray velocimetry in healthy adults
X-ray velocimetry (XV) has been utilized in preclinical models to assess lung motion and regional ventilation, though no s...
A comparative study of in vitro air–liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution
A comparative study of in vitro air–liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution
The airway epithelium is composed of diverse cell types with specialized functions that mediate homeostasis and protect ag...
Prolyl oligopeptidase inhibition ameliorates experimental pulmonary fibrosis both in vivo and in vitro
Prolyl oligopeptidase inhibition ameliorates experimental pulmonary fibrosis both in vivo and in vitro
Pulmonary fibrosis is a progressive disease characterized by lung remodeling due to excessive deposition of extracellular ...
IL-25 induces airway remodeling in asthma by orchestrating the phenotypic changes of epithelial cell and fibrocyte
IL-25 induces airway remodeling in asthma by orchestrating the phenotypic changes of epithelial cell and fibrocyte
Previous studies have shown that IL-25 levels are increased in patients with asthma with fixed airflow limitation (FAL). H...
Clinical practice of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease
Clinical practice of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease
Non-invasive ventilation (NIV) is an evidence-based treatment for acute respiratory failure in chronic obstructive pulmona...
Acute cigarette smoke exposure leads to higher viral infection in human bronchial epithelial cultures by altering interferon, glycolysis and GDF15-related pathways
Acute cigarette smoke exposure leads to higher viral infection in human bronchial epithelial cultures by altering interferon, glycolysis and GDF15-related pathways
Acute exacerbations of chronic inflammatory lung diseases, such as chronic obstructive pulmonary disease (COPD), are frequ...
Accumulation of oxysterols in the erythrocytes of COVID-19 patients as a biomarker for case severity
Accumulation of oxysterols in the erythrocytes of COVID-19 patients as a biomarker for case severity
Due to the high risk of COVID-19 patients developing thrombosis in the circulating blood, atherosclerosis, and myocardial ...
Correction to: Impact of Haemophilus influenzae type b combination vaccination on asthma symptoms and pneumonia in 5-year-old children in rural Bangladesh: a longitudinal study and comparison with a previous cross-sectional study
Correction to: Impact of Haemophilus influenzae type b combination vaccination on asthma symptoms and pneumonia in 5-year-old children in rural Bangladesh: a longitudinal study and comparison with a previous cross-sectional study
The authors gratefully acknowledge all participating children who generously provided their invaluable blood and stool sam...
Lung function trajectories in patients with idiopathic pulmonary fibrosis
Lung function trajectories in patients with idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease characterised by decline in lung ...
Rhinovirus infection induces secretion of endothelin-1 from airway epithelial cells in both in vitro and in vivo models
Rhinovirus infection induces secretion of endothelin-1 from airway epithelial cells in both in vitro and in vivo models
Rhinovirus (RV) infection of airway epithelial cells triggers asthma exacerbations, during which airway smooth muscle (ASM...
Polo-like kinase 1 promotes pulmonary hypertension
Polo-like kinase 1 promotes pulmonary hypertension
Pulmonary hypertension (PH) is a lethal vascular disease with limited therapeutic options. The mechanistic connections bet...
Race-specific spirometry equations may overestimate asthma control in Black children and adolescents
Race-specific spirometry equations may overestimate asthma control in Black children and adolescents
A growing body of evidence suggests that use of race terms in spirometry reference equations underestimates disease burden...
Apoptosis inhibitor of macrophage (AIM)/CD5L is involved in the pathogenesis of COPD
Apoptosis inhibitor of macrophage (AIM)/CD5L is involved in the pathogenesis of COPD
Alveolar macrophages (AMs) and AM-produced matrix metalloprotease (MMP)-12 are known to play critical roles in the pathoge...
Echocardiographic evaluation of right heart failure which might be associated with DNA damage response in SU5416-hypoxia induced pulmonary hypertension rat model
Echocardiographic evaluation of right heart failure which might be associated with DNA damage response in SU5416-hypoxia induced pulmonary hypertension rat model
Right heart failure is the leading cause of death in pulmonary hypertension (PH), and echocardiography is a commonly used ...
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