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Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Interleukin (IL)-26 is produced by T helper type 17 (Type 17) cells and exerts immunomodulatory plus antimicrobial effects...
Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis
Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis
Sarcoidosis is a systemic granulomatous disease of unknown etiology primarily affecting the lungs. Treatment is needed whe...
Human genetic associations of the airway microbiome in chronic obstructive pulmonary disease
Human genetic associations of the airway microbiome in chronic obstructive pulmonary disease
Little is known about the relationships between human genetics and the airway microbiome. Deeply sequenced airway metageno...
Early-life house dust mite aeroallergen exposure augments cigarette smoke-induced myeloid inflammation and emphysema in mice
Early-life house dust mite aeroallergen exposure augments cigarette smoke-induced myeloid inflammation and emphysema in mice
Longitudinal studies have identified childhood asthma as a risk factor for obstructive pulmonary disease (COPD) and asthma...
Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis
Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis
No effective therapies for pulmonary fibrosis (PF) exist because of the unclear molecular pathogenesis and the lack of eff...
Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures
Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures
Environmental/occupational exposures cause significant lung diseases. Agricultural organic dust extracts (ODE) and bacteri...
Phenotypes and outcome of diffuse pulmonary non-amyloid light chain deposition disease
Phenotypes and outcome of diffuse pulmonary non-amyloid light chain deposition disease
Light chain deposition disease (LCDD) is a very rare entity. Clinical manifestations of LCDD vary according to the organs ...
Use of non-small cell lung cancer multicellular tumor spheroids to study the impact of chemotherapy
Use of non-small cell lung cancer multicellular tumor spheroids to study the impact of chemotherapy
Lung cancers represent the main cause of cancer related-death worldwide. Recently, immunotherapy alone or in combination w...
NR2F2 alleviates pulmonary fibrosis by inhibition of epithelial cell senescence
NR2F2 alleviates pulmonary fibrosis by inhibition of epithelial cell senescence
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fatal, and aging-associated interstitial lung disease with ...
A WNT mimetic with broad spectrum FZD-specificity decreases fibrosis and improves function in a pulmonary damage model
A WNT mimetic with broad spectrum FZD-specificity decreases fibrosis and improves function in a pulmonary damage model
Wnt/β-catenin signaling is critical for lung development and AT2 stem cell maintenance in adults, but excessive pathw...
Updated reference values for static lung volumes from a healthy population in Austria
Updated reference values for static lung volumes from a healthy population in Austria
Reference values for lung volumes are necessary to identify and diagnose restrictive lung diseases and hyperinflation, but...
The safety and potential efficacy of exosomes overexpressing CD24 (EXO-CD24) in mild-moderate COVID-19 related ARDS
The safety and potential efficacy of exosomes overexpressing CD24 (EXO-CD24) in mild-moderate COVID-19 related ARDS
EXO-CD24 are exosomes genetically manipulated to over-express Cluster of Differentiation (CD) 24. It consists of two break...
Longitudinal BMI change and outcomes in Chronic Obstructive Pulmonary Disease: a nationwide population-based cohort study
Longitudinal BMI change and outcomes in Chronic Obstructive Pulmonary Disease: a nationwide population-based cohort study
The association between longitudinal body mass index (BMI) change and clinical outcomes in patients with chronic obstructi...
Clinical characterization and outcomes of impulse oscillometry-defined bronchodilator response: an ECOPD cohort-based study
Clinical characterization and outcomes of impulse oscillometry-defined bronchodilator response: an ECOPD cohort-based study
The clinical significance of the impulse oscillometry-defined small airway bronchodilator response (IOS-BDR) is not well-k...
A novel quinoline with airway relaxant effects and anti-inflammatory properties
A novel quinoline with airway relaxant effects and anti-inflammatory properties
In chronic pulmonary diseases characterized by inflammation and airway obstruction, such as asthma and COPD, there are unm...
Respiratory entrainment related reverse triggering in mechanically ventilated children
Respiratory entrainment related reverse triggering in mechanically ventilated children
The underlying pathophysiological pathways how reverse triggering is being caused are not fully understood. Respiratory en...
Early smoking lead to worse prognosis of COPD patients: a real world study
Early smoking lead to worse prognosis of COPD patients: a real world study
Smoking remains a major risk factor for the development and progression of chronic obstructive pulmonary disease (COPD). D...
The role of lung biopsy for diagnosis and prognosis of interstitial lung disease in systemic sclerosis: a systematic literature review
The role of lung biopsy for diagnosis and prognosis of interstitial lung disease in systemic sclerosis: a systematic literature review
The prognostic and theragnostic role of histopathological subsets in systemic sclerosis interstitial lung disease (SSc-ILD...
Evaluation of computed tomography in the diagnosis of ultrasound-proven diaphragm dysfunction
Evaluation of computed tomography in the diagnosis of ultrasound-proven diaphragm dysfunction
Computed tomography (CT) is routinely employed on the evaluation of dyspnea, yet limited data exist on its assessment of d...
The role of sialidase Neu1 in respiratory diseases
The role of sialidase Neu1 in respiratory diseases
Neu1 is a sialidase enzyme that plays a crucial role in the regulation of glycosylation in a variety of cellular processes...
The additional value of 18F-FDG PET/CT imaging in guiding the treatment strategy of non-tuberculous mycobacterial patients
The additional value of 18F-FDG PET/CT imaging in guiding the treatment strategy of non-tuberculous mycobacterial patients
Non-tuberculous mycobacteria (NTM) infection is an increasing health problem due to delaying an effective treatment. Howev...
Two single lung transplantations from one donor: lung twinning in the LAS era
Two single lung transplantations from one donor: lung twinning in the LAS era
The implementation of the Lung Allocation Score (LAS) in the Eurotransplant international collaborative framework decrease...
Lung tissue expression of epithelial injury markers is associated with acute lung injury severity but does not discriminate sepsis from ARDS
Lung tissue expression of epithelial injury markers is associated with acute lung injury severity but does not discriminate sepsis from ARDS
Acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in critically ill patients, and diffus...
Cough flows as a criterion for decannulation of autonomously breathing patients with tracheostomy tubes
Cough flows as a criterion for decannulation of autonomously breathing patients with tracheostomy tubes
Adequate cough or exsufflation flow can indicate an option for safe tracheostomy decannulation to noninvasive management. ...
Alterations of lung microbiota in lung transplant recipients with pneumocystis jirovecii pneumonia
Alterations of lung microbiota in lung transplant recipients with pneumocystis jirovecii pneumonia
Increasing evidence revealed that lung microbiota dysbiosis was associated with pulmonary infection in lung transplant rec...