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Performance and application of the total-body PET/CT scanner: a literature review
Performance and application of the total-body PET/CT scanner: a literature review
The total-body positron emission tomography/computed tomography (PET/CT) system, with a long axial field of view, represen...
In-vivo inhibition of neutral endopeptidase 1 results in higher absorbed tumor doses of [177Lu]Lu-PP-F11N in humans: the lumed phase 0b study
In-vivo inhibition of neutral endopeptidase 1 results in higher absorbed tumor doses of [177Lu]Lu-PP-F11N in humans: the lumed phase 0b study
A new generation of radiolabeled minigastrin analogs delivers low radiation doses to kidneys and are considered relatively...
Evaluating the biodistribution for [68Ga]Ga-PSMA-11 and [18F]F-PSMA-1007 PET/CT with an inter- and intrapatient based analysis
Evaluating the biodistribution for [68Ga]Ga-PSMA-11 and [18F]F-PSMA-1007 PET/CT with an inter- and intrapatient based analysis
Liver uptake in [68Ga]Ga-PSMA-11 PET is used as an internal reference in addition to clinical parameters to select patient...
Neuroimaging-guided diagnosis of possible FTLD-FUS pathology: a case report
Neuroimaging-guided diagnosis of possible FTLD-FUS pathology: a case report
This case report presents a patient with progressive memory loss and choreiform movements. Neuropsychological tests indica...
Automated extraction of the arterial input function from brain images for parametric PET studies
Automated extraction of the arterial input function from brain images for parametric PET studies
Accurate measurement of the arterial input function (AIF) is crucial for parametric PET studies, but the AIF is commonly d...
Brain 18 F-FDG PET reveals cortico-subcortical hypermetabolic dysfunction in juvenile neuropsychiatric systemic lupus erythematosus
Brain 18 F-FDG PET reveals cortico-subcortical hypermetabolic dysfunction in juvenile neuropsychiatric systemic lupus erythematosus
In juvenile systemic lupus erythematosus (j-SLE) with neuropsychiatric (NP) symptoms, there is a lack of diagnostic biomar...
Repeatability of 18F-FDG uptake in metastatic bone lesions of breast cancer patients and implications for accrual to clinical trials
Repeatability of 18F-FDG uptake in metastatic bone lesions of breast cancer patients and implications for accrual to clinical trials
Standard measures of response such as Response Evaluation Criteria in Solid Tumors are ineffective for bone lesions, often...
Increased lesion detectability in patients with locally advanced breast cancer—A pilot study using dynamic whole-body [18F]FDG PET/CT
Increased lesion detectability in patients with locally advanced breast cancer—A pilot study using dynamic whole-body [18F]FDG PET/CT
Accurate diagnosis of axillary lymph node (ALN) metastases is essential for prognosis and treatment planning in breast can...
Biodistribution and dosimetry of 177Lu-DOTA-IBA for therapy of bone metastases
Biodistribution and dosimetry of 177Lu-DOTA-IBA for therapy of bone metastases
We designed and synthesized a novel bisphosphonate radiopharmaceutical (68 Ga- or 177Lu-labeled DOTA-ibandronate ...
89Zr-labeled ImmunoPET targeting the cancer stem cell antigen CD133 using fully-human antibody constructs
89Zr-labeled ImmunoPET targeting the cancer stem cell antigen CD133 using fully-human antibody constructs
Cancer stem cells play an important role in driving tumor growth and treatment resistance, which makes them a promising th...
Evidence of brain metabolism redistribution from neocortex to primitive brain structures in early acute COVID-19 respiratory syndrome
Evidence of brain metabolism redistribution from neocortex to primitive brain structures in early acute COVID-19 respiratory syndrome
Neuropsychiatric sequelae of COVID-19 have been widely documented in patients with severe neurological symptoms during the...
Improving multi-pinhole CZT myocardial perfusion imaging specificity without changing sensibility by using adapted filter parameters
Improving multi-pinhole CZT myocardial perfusion imaging specificity without changing sensibility by using adapted filter parameters
Meta-analysis show the diagnostic performance of cardiac dedicated multi-pinhole cadmium-zinc-telluride myocardial perfusi...
Evaluation of the theranostic potential of [64Cu]CuCl2 in glioblastoma spheroids
Evaluation of the theranostic potential of [64Cu]CuCl2 in glioblastoma spheroids
Glioblastoma is an extremely aggressive malignant tumor with a very poor prognosis. Due to the increased proliferation rat...
Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA
Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA
P2X7 receptor has emerged as a potentially superior PET imaging marker to TSPO, the gold standard for imaging glial reacti...
Dynamic whole-body [18F]FES PET/CT increases lesion visibility in patients with metastatic breast cancer
Dynamic whole-body [18F]FES PET/CT increases lesion visibility in patients with metastatic breast cancer
Correct classification of estrogen receptor (ER) status is essential for prognosis and treatment planning in patients with...
Pharmacodynamics and biodistribution of [195mPt]cisplatin(CISSPECT®) in head and neck squamous cell carcinoma
Pharmacodynamics and biodistribution of [195mPt]cisplatin(CISSPECT®) in head and neck squamous cell carcinoma
Cisplatin- based chemoradiotherapy is a crucial pillar in the treatment of HNSCC. The use of cisplatin comes with high tox...
Significant reduction of activity retention in the kidneys via optimized linker sequences in radiohybrid-based minigastrin analogs
Significant reduction of activity retention in the kidneys via optimized linker sequences in radiohybrid-based minigastrin analogs
We recently introduced radiohybrid (rh)-based minigastrin analogs e.g., DOTA-rhCCK-18 (DOTA-D-Dap(p-SiFA)-(D-γ-Glu)8-...
The efficacy of short acquisition time using 18F-FDG total-body PET/CT for the identification of pediatric epileptic foci
The efficacy of short acquisition time using 18F-FDG total-body PET/CT for the identification of pediatric epileptic foci
18F-FDG positron emission tomography (PET) plays a crucial part in the evaluation for pediatric epileptic patients prior t...
Evaluation of therapeutic effect and prognostic value of 18F-FDG PET/CT in different treatment nodes of DLBCL patients
Evaluation of therapeutic effect and prognostic value of 18F-FDG PET/CT in different treatment nodes of DLBCL patients
In the present study, we aimed to investigate the role of baseline (B), interim (I) and end-of-treatment (Eot) 18F-FDG PET...
Non-specific irreversible 89Zr-mAb uptake in tumours: evidence from biopsy-proven target-negative tumours using 89Zr-immuno-PET
Non-specific irreversible 89Zr-mAb uptake in tumours: evidence from biopsy-proven target-negative tumours using 89Zr-immuno-PET
Distribution of mAbs into tumour tissue may occur via different processes contributing differently to the 89Zr-mAb uptake ...
Synthesis and preclinical evaluation of [11C]EAI045 as a PET tracer for imaging tumors expressing mutated epidermal growth factor receptor
Synthesis and preclinical evaluation of [11C]EAI045 as a PET tracer for imaging tumors expressing mutated epidermal growth factor receptor
Mutations in the epidermal growth factor receptor (EGFR) kinase domain are common in non-small cell lung cancer. Conventio...
Relaxed fibronectin: a potential novel target for imaging endometriotic lesions
Relaxed fibronectin: a potential novel target for imaging endometriotic lesions
Endometriosis is characterized by the ectopic occurrence of endometrial tissue. Though considered benign, endometriotic le...
The image quality and feasibility of solitary delayed [68 Ga]Ga-PSMA-11 PET/CT using long field-of-view scanning in patients with prostate cancer
The image quality and feasibility of solitary delayed [68 Ga]Ga-PSMA-11 PET/CT using long field-of-view scanning in patients with prostate cancer
Previous studies have demonstrated that delayed [68 Ga]Ga-PSMA PET/CT imaging improves lesion detection compared ...
Risk of treatment-altering haematological toxicity and its dependence on bone marrow doses in peptide receptor radionuclide therapy
Risk of treatment-altering haematological toxicity and its dependence on bone marrow doses in peptide receptor radionuclide therapy
Peptide receptor radionuclide therapy is effective in treating neuroendocrine tumours, but treatment may be limited by kid...
Spherization indices measured by resting SPECT improve risk stratification in patients with ischemia with non-obstructive coronary artery disease (INOCA)
Spherization indices measured by resting SPECT improve risk stratification in patients with ischemia with non-obstructive coronary artery disease (INOCA)
The prevalence of ischemia with non-obstructive coronary artery disease (INOCA) is substantial, but its risk stratificatio...
Exploring the impact of PEGylation on pharmacokinetics: a size-dependent effect of polyethylene glycol on prostate-specific membrane antigen inhibitors
Exploring the impact of PEGylation on pharmacokinetics: a size-dependent effect of polyethylene glycol on prostate-specific membrane antigen inhibitors
Prostate cancer is the second most frequent cancer and the fifth leading cause of cancer-related deaths in men. Prostate-s...
A histogram of [18F]BBPA PET imaging differentiates non-neoplastic lesions from malignant brain tumors
A histogram of [18F]BBPA PET imaging differentiates non-neoplastic lesions from malignant brain tumors
[18F]BBPA PET/CT and MRI acquisition[18F]BBPA PET/CT and MRI were performed within 1 week on separate days. For [18F]BBPA ...
ParaPET: non-invasive deep learning method for direct parametric brain PET reconstruction using histoimages
ParaPET: non-invasive deep learning method for direct parametric brain PET reconstruction using histoimages
The indirect method for generating parametric images in positron emission tomography (PET) involves the acquisition and re...
Repeatability of [15O]H2O PET imaging for lower extremity skeletal muscle perfusion: a test–retest study
Repeatability of [15O]H2O PET imaging for lower extremity skeletal muscle perfusion: a test–retest study
[15O]H2O PET/CT allows noninvasive quantification of tissue perfusion and can potentially play a future role in the diagno...
Comparison of 18F-FDG PET and arterial spin labeling MRI in evaluating Alzheimer’s disease and amnestic mild cognitive impairment using integrated PET/MR
Comparison of 18F-FDG PET and arterial spin labeling MRI in evaluating Alzheimer’s disease and amnestic mild cognitive impairment using integrated PET/MR
Developing biomarkers for early stage AD patients is crucial. Glucose metabolism measured by 18F-FDG PET is the most commo...
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