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P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study
P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study
PET imaging of activated microglia has improved our understanding of the pathology behind disability progression in MS, an...
PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil
PET imaging of GABAA receptors in pancreatic islets by [11C]flumazenil
Type 1 diabetes (T1D) is an autoimmune disease characterized by a progressive β-cell destruction. There are no clinic...
Impact of cognitive impairment on heart failure prognosis: insights into central nervous system mechanism
Impact of cognitive impairment on heart failure prognosis: insights into central nervous system mechanism
Epidemiological studies have indicated that patients with heart failure (HF) who experience cognitive impairment (CI) have...
Radiation exposure and protection advice after [177Lu]Lu-DOTA-TATE therapy in China
Radiation exposure and protection advice after [177Lu]Lu-DOTA-TATE therapy in China
We conducted a study on radiation exposure in patients with gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) tre...
Imaging tumor and ascites-associated macrophages in a mouse model of metastatic ovarian cancer
Imaging tumor and ascites-associated macrophages in a mouse model of metastatic ovarian cancer
Tumor-Associated Macrophages (TAMs) play a critical role in the pathogenesis and progression of ovarian cancer, a lethal g...
Machine learning for prognostic prediction in coronary artery disease with SPECT data: a systematic review and meta-analysis
Machine learning for prognostic prediction in coronary artery disease with SPECT data: a systematic review and meta-analysis
Single-photon emission computed tomography (SPECT) analysis relies on qualitative visual assessment or semi-quantitative m...
First-in-human study of 99mTc-labeled fucoidan, a SPECT tracer targeting P-selectin
First-in-human study of 99mTc-labeled fucoidan, a SPECT tracer targeting P-selectin
Activation of endothelial cells and platelets in atherothrombosis is characterized by upregulation of P-selectin. As a con...
Quantification of [99mTc]Tc-HDP bone SPECT/CT: can we improve the body weight based standardized uptake value with a more robust normalization?
Quantification of [99mTc]Tc-HDP bone SPECT/CT: can we improve the body weight based standardized uptake value with a more robust normalization?
The introduction of quantitative SPECT/CT allows more objective assessments of tracer accumulation in SPECT. However stand...
Predicting survival, neurotoxicity and response in B-cell lymphoma patients treated with CAR-T therapy using an imaging features-based model
Predicting survival, neurotoxicity and response in B-cell lymphoma patients treated with CAR-T therapy using an imaging features-based model
This multicentre retrospective observational study aims to develop imaging-based prognostic and predictive models for rela...
The value of radiomics based on 2-[18 F]FDG PET/CT in predicting WHO/ISUP grade of clear cell renal cell carcinoma
The value of radiomics based on 2-[18 F]FDG PET/CT in predicting WHO/ISUP grade of clear cell renal cell carcinoma
The aim is to develop and validate radiomics based on 2-[18F]fluoro-D-glucose positron emission tomography/computed tomogr...
Impact of shortening time on diagnosis of 18F-florbetaben PET
Impact of shortening time on diagnosis of 18F-florbetaben PET
18F-Florbetaben amyloid positron emission tomography (PET) scan is crucial for diagnosing Alzheimer’s disease, typic...
Experimental study of early evaluation of radiosensitivity in mouse models of lung cancers using 89Zr-anti-γH2AX-TAT PET imaging
Experimental study of early evaluation of radiosensitivity in mouse models of lung cancers using 89Zr-anti-γH2AX-TAT PET imaging
Early evaluation of radiation sensitivity in lung cancer patients can facilitate the transition to personalized treatment ...
Distinguishing lymphoma from benign lymph node diseases in fever of unknown origin using PET/CT radiomics
Distinguishing lymphoma from benign lymph node diseases in fever of unknown origin using PET/CT radiomics
A considerable portion of patients with fever of unknown origin (FUO) present concomitant lymphadenopathy. Diseases within...
Influence of fasting prior to 18F-rhPSMA-7.3 (Flotufolastat F-18) PET/CT on biodistribution and tumor uptake
Influence of fasting prior to 18F-rhPSMA-7.3 (Flotufolastat F-18) PET/CT on biodistribution and tumor uptake
Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, Rosso S, Coebergh JW, Comber H, et al. Cancer incidence and mortality p...
An automated pheochromocytoma and paraganglioma lesion segmentation AI-model at whole-body 68Ga- DOTATATE PET/CT
An automated pheochromocytoma and paraganglioma lesion segmentation AI-model at whole-body 68Ga- DOTATATE PET/CT
Somatostatin receptor (SSR) targeting radiotracer 68Ga-DOTATATE is used for Positron Emission Tomography (PET)/Computed To...
Localized FDG loss in lung cancer lesions
Localized FDG loss in lung cancer lesions
Analysis of [18F]-Fluorodeoxyglucose (FDG) kinetics in cancer has been most often limited to the evaluation of the average...
The intra- and interobserver variability of PSMA-expression scores in patients with primary prostate cancer
The intra- and interobserver variability of PSMA-expression scores in patients with primary prostate cancer
Present study, which investigated the intra- and interobserver variability of PSMA-expression scores of primary prostate t...
Matched-pair analysis of mCRPC patients receiving 177Lu-labeled PSMA-targeted radioligand therapy in a 4-week versus 6-week treatment interval
Matched-pair analysis of mCRPC patients receiving 177Lu-labeled PSMA-targeted radioligand therapy in a 4-week versus 6-week treatment interval
The optimal regimen for 177Lu-labeled prostate-specific membrane antigen-targeted radioligand therapy, including treatment...
Validation of radiolabelled exendin for beta cell imaging by ex vivo autoradiography and immunohistochemistry of human pancreas
Validation of radiolabelled exendin for beta cell imaging by ex vivo autoradiography and immunohistochemistry of human pancreas
Estimation of beta cell mass is currently restricted to evaluating pancreatic tissue samples, which provides limited infor...
Comparative benefits of Ki and SUV images in lesion detection during PET/CT imaging
Comparative benefits of Ki and SUV images in lesion detection during PET/CT imaging
Clinical application of the tracer net influx rate (Ki) imaging in PET/CT remains limited, due to a lack of evidence demon...
Appearance time of blood in the brain as a possible indicator of oxygen extraction fraction: a feasibility study
Appearance time of blood in the brain as a possible indicator of oxygen extraction fraction: a feasibility study
Imaging examination of cerebral blood flow (CBF), oxygen extraction fraction (OEF), and metabolic rate of oxygen is crucia...
Heparin does not improve myocardial glucose metabolism suppression in [18 F]FDG PET/CT in patients with low β-hydroxybutyrate level
Heparin does not improve myocardial glucose metabolism suppression in [18 F]FDG PET/CT in patients with low β-hydroxybutyrate level
Inadequate myocardial glucose metabolism suppression (GMS) can hamper interpretation of cardiac [18F]fluorodeoxyglucose (F...
[18F]TFB PET/CT misses intense [124I]iodine-avid metastases after redifferentiation therapy in metastatic thyroid cancer
[18F]TFB PET/CT misses intense [124I]iodine-avid metastases after redifferentiation therapy in metastatic thyroid cancer
Fluorine 18-labelled tetrafluoroborate ([18F]TFB) is a substrate for the sodium/iodide symporter. In thyroid cancer, [18F]...
Diagnostic and evaluative efficiency of 68Ga-FAPI-04 in skeletal muscle injury
Diagnostic and evaluative efficiency of 68Ga-FAPI-04 in skeletal muscle injury
Skeletal muscles are vital for daily function, yet assessing their injuries remain challenging. We aimed to elucidate the ...