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From the cauldron of conflict: Endogenous gene regulation by piRNA and other modes of adaptation enabled by selfish transposable elements
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Out with the old, in with the new: Meiotic driving of sex chromosome evolution
Out with the old, in with the new: Meiotic driving of sex chromosome evolution
During meiosis in sexually reproducing organisms, a reductive cell division produces haploid gametes (sperm and egg) that ...
WHO elements – A new category of selfish genetic elements at the borderline between homing elements and transposable elements
WHO elements – A new category of selfish genetic elements at the borderline between homing elements and transposable elements
Homing genetic elements are a form of selfish DNA that inserts into a specific target site in the genome and spreads throu...
Cover image of cell death and resilience in health and disease
Cover image of cell death and resilience in health and disease
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Mitochondrial control of lymphocyte homeostasis
Mitochondrial control of lymphocyte homeostasis
Volumes 161–162, September–October 2024, Pages 42-53Author links open overlay panel, , AbstractMitochondria play a multitu...
Genetic conflicts in budding yeast: The 2μ plasmid as a model selfish element
Genetic conflicts in budding yeast: The 2μ plasmid as a model selfish element
Intergenomic conflict can occur between different species that antagonistically coevolve, such as predator and their prey,...
Symbiotic symphony: Understanding host-microbiota dialogues in a spatial context
Symbiotic symphony: Understanding host-microbiota dialogues in a spatial context
The ‘chemical Darwinian’ definition of life is a ‘self-sustained chemical system capable of undergoing Darwinian evolution...
Mitochondrial dynamics: Regulating cell metabolism, homoeostasis, health and disease
Mitochondrial dynamics: Regulating cell metabolism, homoeostasis, health and disease
Volumes 161–162, September–October 2024, Pages 20-21Author links open overlay panel, Section snippetsAcknowledgementsWe th...
The interplay between mitochondrial dynamics and autophagy: From a key homeostatic mechanism to a driver of pathology
The interplay between mitochondrial dynamics and autophagy: From a key homeostatic mechanism to a driver of pathology
ADOAAutosomal dominant optic atrophyAMBRA1Autophagy/BECN1regulator-1AMPKAMP-activated protein kinaseARIH1Ariadne RBR E3 ub...
PSRs: Selfish chromosomes that manipulate reproductive development
PSRs: Selfish chromosomes that manipulate reproductive development
Volumes 159–160, June–July 2024, Pages 66-73Author links open overlay panel, AbstractB chromosomes are intriguing “selfish...
Maintenance of satellite DNA stability
Maintenance of satellite DNA stability
Volumes 159–160, June–July 2024, Pages 64-65Author links open overlay panelSection snippetsDeclaration of Competing Intere...
The wonderful wanderer
The wonderful wanderer
Volumes 159–160, June–July 2024, Pages 62-63Author links open overlay panelSara Prescott a bShow moreReferences (9)There a...
The role of mitochondrial dynamics in oocyte and early embryo development
The role of mitochondrial dynamics in oocyte and early embryo development
Over the past decade, there has been a significant increase in our understanding of the profound impact mitochondrial dysf...
Super-resolution microscopies, technological breakthrough to decipher mitochondrial structure and dynamic.
Super-resolution microscopies, technological breakthrough to decipher mitochondrial structure and dynamic.
Volumes 159–160, June–July 2024, Pages 38-51Author links open overlay panel, , AbstractMitochondria are complex organelles...
Sexual conflict drive in the rapid evolution of new gametogenesis genes
Sexual conflict drive in the rapid evolution of new gametogenesis genes
Volumes 159–160, June–July 2024, Pages 27-37Author links open overlay panel, , AbstractThe evolutionary forces underlying ...
Stress granule and P-body clearance: Seeking coherence in acts of disappearance
Stress granule and P-body clearance: Seeking coherence in acts of disappearance
Stress granules (SGs) and P-bodies (PBs) are paradigm biomolecular condensates, also referred to as membraneless organelle...
rDNA transcription, replication and stability in Saccharomyces cerevisiae
rDNA transcription, replication and stability in Saccharomyces cerevisiae
The ribosomal DNA locus (rDNA) is central for the functioning of cells because it encodes ribosomal RNAs, key components o...
Stress granules and P-bodies – New ideas and experimental models worth exploring
Stress granules and P-bodies – New ideas and experimental models worth exploring
Volume 158, May 2024, Pages 1-2Author links open overlay panelSection snippetsDeclaration of Competing InterestI have no c...
P-body-like condensates in the germline
P-body-like condensates in the germline
P-bodies are cytoplasmic condensates that accumulate low-translation mRNAs for temporary storage before translation or deg...
Telomere-specific regulation of TERRA and its impact on telomere stability
Telomere-specific regulation of TERRA and its impact on telomere stability
Volume 157, April 2024, Pages 3-23Author links open overlay panel, , Highlights•Transcription of telomeric repeats contrib...
Editorial: Special issue SCDB “Cell death and survival”: Cell death and resilience in health and disease
Editorial: Special issue SCDB “Cell death and survival”: Cell death and resilience in health and disease
H. Kalkavan et al.Non-lethal outcomes of engaging regulated cell death pathways in cancerNat. Cancer(2023)N. Popgeorgiev e...
Shedding light on mitochondrial outer-membrane permeabilization and membrane potential: State of the art methods and biosensors
Shedding light on mitochondrial outer-membrane permeabilization and membrane potential: State of the art methods and biosensors
Membrane structural integrity is essential for optimal mitochondrial function. These organelles produce the energy needed ...
Death and survival from executioner caspase activation
Death and survival from executioner caspase activation
Caspases (Cysteine-ASPartic proteASES) are a group of proteases that cleave their substrates after specific short tetrapep...
An emerging role for the endoplasmic reticulum in stress granule biogenesis
An emerging role for the endoplasmic reticulum in stress granule biogenesis
Stress granules (SGs) are a prominently studied member of a family of ribonucleoprotein (RNP) granules evident at many pha...
Composition and function of stress granules and P-bodies in plants
Composition and function of stress granules and P-bodies in plants
Stress Granules (SGs) and Processing-bodies (P-bodies) are biomolecular condensates formed in the cell with the highly con...
The implications of physiological biomolecular condensates in amyotrophic lateral sclerosis
The implications of physiological biomolecular condensates in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting 1 in 50,000 individuals per year and is...
The vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine
The vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine
The parasympathetic nervous system via the vagus nerve exerts profound influence over the heart. Together with the sympath...
The gut-brain axis and cognitive control: A role for the vagus nerve
The gut-brain axis and cognitive control: A role for the vagus nerve
‘Survival of the fittest’ is driven by a species’ constant adaptation to a changing environment, which requires both aware...
Molecular cell types as functional units of the efferent vagus nerve
Molecular cell types as functional units of the efferent vagus nerve
The vagus nerve, a cranial nerve named for its “wandering” path from brainstem to bowel, is a vital conduit for brain-body...
Vagal pathways for systemic regulation of glucose metabolism
Vagal pathways for systemic regulation of glucose metabolism
Glucose is undoubtedly the primary energy fuel for practically all tissues in mammals. Because both hypo- and hyperglycemi...
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