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Unravelling the mysteries of human embryogenesis
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The non-coding genome in early human development – Recent advancements
Volume 131, November 2022, Pages 4-13AbstractNot that long ago, the human genome was discovered to be mainly non-coding, t...
Glucose and oxygen in the early intrauterine environment and their role in developmental abnormalities
Volume 131, November 2022, Pages 25-34AbstractThe early life environment can have profound impacts on the developing conce...
Recent advances in understanding cell types during human gastrulation
Gastrulation is a fundamental process during embryonic development, conserved across all multicellular animals [1]. In the...
Fetal germ cell development in humans, a link with infertility
Volume 131, November 2022, Pages 58-65AbstractGametes are cells that have the unique ability to give rise to new individua...
Human placental development and function
Volume 131, November 2022, Pages 66-77AbstractThe placenta is a transient fetal organ that plays a critical role in the he...
Luminogenesis and hydraulics in development
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Trans-epithelial fluid flow and mechanics of epithelial morphogenesis
Volume 131, November 2022, Pages 146-159AbstractActive fluid transport across epithelial monolayers is emerging as a major...
Computational approaches for simulating luminogenesis
Volume 131, November 2022, Pages 173-185AbstractLumens, liquid-filled cavities surrounded by polarized tissue cells, are e...
Organoids as a novel tool in modelling infectious diseases
ACE2angiotensin-converting enzyme 2iPSCinduced-pluripotent stem cellsRSVRespiratory Syncytial VirusHPIV-3human parainfluen...
Epigenetic regulation of inflammation: The metabolomics connection
ACLFAcute-on-chronic liver failureBCAAsBranched-chain amino acidsCNOChronic nonbacterial osteomyelitisCOPDChronic obstruct...
Modelling adult stem cells and their niche in health and disease with epithelial organoids
Adult stem cells are responsible for homoeostasis and regeneration of epithelial tissues. Stem cell function is regulated ...
Balance between the cell viability and death in 3D
Cell death is a phenomenon, frequently perceived as an absolute event for cell, tissue and the organ. However, the rising ...
The impact of antidepressants on human neurodevelopment: Brain organoids as experimental tools
The use of antidepressants during pregnancy benefits the mother's well-being, but the effects of such substances on neurod...
Time, space, and diversity
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Epigenetic regulation of inflammation in insulin resistance
Epigenetics focuses on the study of changes in gene expression based on modifications that do not interfere with the DNA s...
Editorial for the special issue “Driving forces behind the wiring of neuronal circuits”
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The role of protein arginine N-methyltransferases in inflammation
ADMAasymmetric dimethylarginineAFLDalcoholic fatty liver diseaseAIPIAg-induced pulmonary inflammationAMI-1Arginine methylt...
For Special Issue: Tissue size and shape
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Orchestrating human neocortex development across the scales; from micro to macro
Volume 130, October 2022, Pages 24-36AbstractHow our brains have developed to perform the many complex functions that make...
Mechanical control of tissue shape: Cell-extrinsic and -intrinsic mechanisms join forces to regulate morphogenesis
Volume 130, October 2022, Pages 45-55AbstractDuring vertebrate development, cells must proliferate, move, and differentiat...
Mechanics of neural tube morphogenesis
Volume 130, October 2022, Pages 56-69AbstractThe neural tube is an important model system of morphogenesis representing th...
The influence of tissue spatial geometry and functional organisation on liver regeneration
Volume 130, October 2022, Pages 70-78AbstractThe adult liver exerts crucial functions, including nutrient metabolism and s...
Regulation of tissue architecture and stem cell dynamics to sustain homeostasis and repair in the skin epidermis
Volume 130, October 2022, Pages 79-89AbstractStratified epithelia are made up of several layers of cells, which act as a p...
The tubulin code: Empowering microtubules
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Pinpointing the locus of GABAergic vulnerability in Alzheimer’s disease
Available online 10 August 2022AbstractThe early stages of Alzheimer’s disease (AD) have been linked to microcircuit dysfu...
Editorial: Special issue on synthetic developmental biology
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Multi-layered transcriptional control of cranial neural crest development
The neural crest (NC) is an emblematic population of embryonic stem-like cells with remarkable migratory ability. These di...
Molecular dissection of cognition, emotion and thoughts
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