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Involvement of CRMP2 Phosphorylation in Amyloid Beta-induced Tau Phosphorylation of Hippocampal Neurons in Alzheimer’s Disease Mouse Model
Involvement of CRMP2 Phosphorylation in Amyloid Beta-induced Tau Phosphorylation of Hippocampal Neurons in Alzheimer’s Disease Mouse Model
Alzheimer’s disease (AD) is the most common form of dementia, characterized by amyloid-β (Aβ) deposition a...
Application of Casein Micelles for Targeting Huntington’s Disease in Experimental Zebrafish Model
Application of Casein Micelles for Targeting Huntington’s Disease in Experimental Zebrafish Model
Huntington’s disease (HD) is an incorrigible neuropsychiatric disorder with reduced cognition and motor abnormalitie...
Specific Mode Electroacupuncture Stimulation Mediates the Delivery of NGF Across the Hippocampus Blood–Brain Barrier Through p65-VEGFA-TJs to Improve the Cognitive Function of MCAO/R Convalescent Rats
Specific Mode Electroacupuncture Stimulation Mediates the Delivery of NGF Across the Hippocampus Blood–Brain Barrier Through p65-VEGFA-TJs to Improve the Cognitive Function of MCAO/R Convalescent Rats
Cognitive impairment frequently presents as a prevalent consequence following stroke, imposing significant burdens on pati...
The Proteomic Analysis of Chronic Migraine Exosomes Reveals Disease Patterns and Potential Biomarkers
The Proteomic Analysis of Chronic Migraine Exosomes Reveals Disease Patterns and Potential Biomarkers
Exosomes have been identified as optimal biomarkers to screen for multiple diseases. However, few studies focus on the abu...
Synthesis and Neurobehavioral Evaluation of a Potent Multitargeted Inhibitor for the Treatment of Alzheimer’s Disease
Synthesis and Neurobehavioral Evaluation of a Potent Multitargeted Inhibitor for the Treatment of Alzheimer’s Disease
Alzheimer’s disease (AD) poses a significant health challenge worldwide, affecting millions of individuals, and proj...
A Mouse Model of Sporadic Alzheimer’s Disease with Elements of Major Depression
A Mouse Model of Sporadic Alzheimer’s Disease with Elements of Major Depression
After olfactory bulbectomy, animals are often used as a model of major depression or sporadic Alzheimer’s disease an...
Biflavonoid Methylchamaejasmin and Khaya grandifoliola Extract Inhibit NLRP3 Inflammasome in THP-1 Cell Model of Neuroinflammation
Biflavonoid Methylchamaejasmin and Khaya grandifoliola Extract Inhibit NLRP3 Inflammasome in THP-1 Cell Model of Neuroinflammation
Neuroinflammation is a common hallmark of Alzheimer’s disease (AD), with NLRP3 inflammasome proven to be activated i...
Hypoxic-Ischemic Encephalopathy: Pathogenesis and Promising Therapies
Hypoxic-Ischemic Encephalopathy: Pathogenesis and Promising Therapies
Hypoxic-ischemic encephalopathy (HIE) is a brain lesion caused by inadequate blood supply and oxygen deprivation, often oc...
Correction to: Hypoxic-Ischemic Encephalopathy: Pathogenesis and Promising Therapies
Correction to: Hypoxic-Ischemic Encephalopathy: Pathogenesis and Promising Therapies
Cite this articleYang, M., Wang, K., Liu, B. et al. Correction to: Hypoxic-Ischemic Encephalopathy: Pathogenesis and Promi...
Caspase-12 is Expressed in Purkinje Neurons and Prevents Psychiatric-Like Behavior in Mice
Caspase-12 is Expressed in Purkinje Neurons and Prevents Psychiatric-Like Behavior in Mice
Caspase-12 is a caspase family member for which functions in regulating cell death and inflammation have previously been s...
Physical Exercise Improves the Neuronal Function in Ischemic Stroke Via Microglial CB2R/P2Y12 Signaling
Physical Exercise Improves the Neuronal Function in Ischemic Stroke Via Microglial CB2R/P2Y12 Signaling
Physical exercise (PE) may be the single most important and accessible lifestyle habit throughout life, it inhibits the ne...
Calorie Restriction Attenuates Memory Impairment and Reduces Neuroinflammation in Obese Aged Rats
Calorie Restriction Attenuates Memory Impairment and Reduces Neuroinflammation in Obese Aged Rats
Obesity and aging collectively potentiate inflammatory responses, particularly within the central nervous system. Managing...
The Receptor for Advanced Glycation End-products in the Mouse Anterior Cingulate Cortex is Involved in Neuron‒Astrocyte Coupling in Chronic Inflammatory Pain and Anxiety Comorbidity
The Receptor for Advanced Glycation End-products in the Mouse Anterior Cingulate Cortex is Involved in Neuron‒Astrocyte Coupling in Chronic Inflammatory Pain and Anxiety Comorbidity
Previous studies have shown that astrocyte activation in the anterior cingulate cortex (ACC), accompanied by upregulation ...
Ursonic Acid Ameliorates H2O2-Induced Oxidative Damage in PC12 Cells and Prolonged the Lifespan in C. elegans by Activating MAPKs/Nrf2/HO-1 Signaling Pathway
Ursonic Acid Ameliorates H2O2-Induced Oxidative Damage in PC12 Cells and Prolonged the Lifespan in C. elegans by Activating MAPKs/Nrf2/HO-1 Signaling Pathway
Growing evidence suggests that plant compounds are emerging as a tremendous source for slowing the onset and progression o...
Assessing the Causal Relationships Between Lipid Species and Stroke by Using Mendelian Randomization
Assessing the Causal Relationships Between Lipid Species and Stroke by Using Mendelian Randomization
Circulating lipids and changes in lipid profiles have long been associated with the development of stroke but causal relat...
Identification of Potential Intervention Targets Involved in Prior Exercise that Attenuates Peripheral Neuropathic Pain by Integrating Transcriptome and Whole-genome Bisulfite Sequencing Analyses
Identification of Potential Intervention Targets Involved in Prior Exercise that Attenuates Peripheral Neuropathic Pain by Integrating Transcriptome and Whole-genome Bisulfite Sequencing Analyses
Changes in DNA methylation and subsequent alterations in gene expression have opened a new direction in research related t...
Double-Negative CD4 CD8 Absolute Count Plays a Mediating Role in the Causal Relationship Between Plasma Lipids and Parkinson’s Disease: A Mendel Randomized Study
Double-Negative CD4 CD8 Absolute Count Plays a Mediating Role in the Causal Relationship Between Plasma Lipids and Parkinson’s Disease: A Mendel Randomized Study
According to certain research, there might be a connection between Parkinson’s disease and plasma lipidome. However,...
Molecular Mediators of Neutrophil Primary Granule Release Following Acute Ischemic Stroke and their Associated Epigenetic Modulation by HDAC2
Molecular Mediators of Neutrophil Primary Granule Release Following Acute Ischemic Stroke and their Associated Epigenetic Modulation by HDAC2
High concentrations of neutrophil degranulation products in the plasma and thrombi are poor prognostic indicators in patie...
Characterizing Genetic-Predisposed Proteins Involving Insomnia by Integrating Genome-Wide Association Study Summary Statistics
Characterizing Genetic-Predisposed Proteins Involving Insomnia by Integrating Genome-Wide Association Study Summary Statistics
Large case–control genome-wide association studies (GWASs) have detected loci associated with insomnia, but how thes...
Correction: Astaxanthin and DHA Supplementation Modulates the Maternal Undernutrition-induced Impairment of Cognitive Behavior and Synaptic Plasticity in Adult Life of Offspring’s -Exploring the Molecular Mechanism
Correction: Astaxanthin and DHA Supplementation Modulates the Maternal Undernutrition-induced Impairment of Cognitive Behavior and Synaptic Plasticity in Adult Life of Offspring’s -Exploring the Molecular Mechanism
Cite this articleAgni, M.B., Hegde, P.S., Rai, P. et al. Correction: Astaxanthin and DHA Supplementation Modulates the Mat...
Insights into the Role of the Glymphatic System in the Pathogenesis of Post-hemorrhagic Hydrocephalus
Insights into the Role of the Glymphatic System in the Pathogenesis of Post-hemorrhagic Hydrocephalus
Recently, it has been well-established that the glymphatic or glial-lymphatic system plays a vital role in the pathophysio...
A Neuron-Like Cellular Model for Severe Tinnitus Associated with Rare Variations in the ANK2 Gene
A Neuron-Like Cellular Model for Severe Tinnitus Associated with Rare Variations in the ANK2 Gene
Tinnitus is the perception of sound without an external source, often associated with changes in the auditory pathway and ...
Identification, Clinical Values, and Prospective Pathway Signaling of Lipid Metabolism Genes in Epilepsy and AED Treatment
Identification, Clinical Values, and Prospective Pathway Signaling of Lipid Metabolism Genes in Epilepsy and AED Treatment
The dysregulation of lipid metabolism has been associated with the etiology and progression of the neurological pathology....
Extracellular Matrix Alterations Due to Early-Life Adversity: Implications for Auditory Learning in Male Sprague–Dawley Rats
Extracellular Matrix Alterations Due to Early-Life Adversity: Implications for Auditory Learning in Male Sprague–Dawley Rats
This study aimed to investigate the impact of early childhood chronic stress on the development of the brain extracellular...
Dose-Dependent Effect of a New Biotin Compound in Hippocampal Remyelination in Rats
Dose-Dependent Effect of a New Biotin Compound in Hippocampal Remyelination in Rats
Demyelination is commonly observed in neurodegenerative disorders, including multiple sclerosis (MS). Biotin supplementati...
Neural Stem/Progenitor Cell Therapy in Patients and Animals with Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-analysis
Neural Stem/Progenitor Cell Therapy in Patients and Animals with Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-analysis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative malady that causes progressive degeneration and loss of motor n...
Common Variants in PLXNA4 and Correlation to Neuroimaging Phenotypes in Healthy, Mild Cognitive Impairment, and Alzheimer’s Disease Cohorts
Common Variants in PLXNA4 and Correlation to Neuroimaging Phenotypes in Healthy, Mild Cognitive Impairment, and Alzheimer’s Disease Cohorts
A comprehensive genome-wide association study (GWAS) has validated the identification of the Plexin-A 4 (PLXNA4) gene as a...
Emerging Trends in Neuroblastoma Diagnosis, Therapeutics, and Research
Emerging Trends in Neuroblastoma Diagnosis, Therapeutics, and Research
This review explores the current understanding and recent advancements in neuroblastoma, one of the most common extracrani...
Identifying Pyroptosis-Hub Genes and Inflammation Cell Type-Related Genes in Ischemic Stroke
Identifying Pyroptosis-Hub Genes and Inflammation Cell Type-Related Genes in Ischemic Stroke
Stroke is the second-leading global cause of death. The damage attributed to the immune storm triggered by ischemia–...
Amyotrophic Lateral Sclerosis and Parkinson's Disease: Brain Tissue Transcriptome Analysis Reveals Interactions
Amyotrophic Lateral Sclerosis and Parkinson's Disease: Brain Tissue Transcriptome Analysis Reveals Interactions
This study utilises amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD) human brain samples from the GEO ...
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