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Dopamine‑iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease
Dopamine‑iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease
All data generated during this study are included in this article and its supplementary information file. As for the metab...
RNA sequencing of olfactory bulb in Parkinson's disease reveals gene alterations associated with olfactory dysfunction
RNA sequencing of olfactory bulb in Parkinson's disease reveals gene alterations associated with olfactory dysfunction
KeywordsTranscriptomicsDifferentially expressed genesWGCNA analysisOlfactionUPSITHub genesOlfactory bulbParkinson's diseas...
The downregulation of Kv1 channels in Lgi1−/− mice is accompanied by a profound modification of its interactome and a parallel decrease in Kv2 channels
The downregulation of Kv1 channels in Lgi1−/− mice is accompanied by a profound modification of its interactome and a parallel decrease in Kv2 channels
KeywordsKv1 channelsKv2 channelsLeucine-rich glioma-inactivated 1 (LGI1)Limbic encephalitisAutosomal-dominant lateral temp...
Molecular mechanisms linking type 2 diabetes mellitus and late-onset Alzheimer's disease: A systematic review and qualitative meta-analysis
Molecular mechanisms linking type 2 diabetes mellitus and late-onset Alzheimer's disease: A systematic review and qualitative meta-analysis
Research evidence indicating common metabolic mechanisms through which type 2 diabetes mellitus (T2DM) increases risk of l...
Low and high-order topological disruption of functional networks in multiple system atrophy with freezing of gait: A resting-state study
Low and high-order topological disruption of functional networks in multiple system atrophy with freezing of gait: A resting-state study
ObjectiveFreezing of gait (FOG), a specific survival-threatening gait impairment, needs to be urgently explored in patient...
BDNF and TRiC-inspired reagent rescue cortical synaptic deficits in a mouse model of Huntington's disease
BDNF and TRiC-inspired reagent rescue cortical synaptic deficits in a mouse model of Huntington's disease
KeywordsHuntington's diseaseBACHDBrain-derived neurotrophic factorSynapseNeuronal activityMulti-array electrodePSD95Pre- a...
Disrupted autonomic pathways in spinal cord injury: Implications for the immune regulation
Disrupted autonomic pathways in spinal cord injury: Implications for the immune regulation
Spinal Cord Injury (SCI) disrupts critical autonomic pathways responsible for the regulation of the immune function. Conse...
Genetic and pathological features encipher the phenotypic heterogeneity of Gerstmann-Sträussler-Scheinker disease
Genetic and pathological features encipher the phenotypic heterogeneity of Gerstmann-Sträussler-Scheinker disease
KeywordsPrion diseasesGerstmann-Sträussler-Scheinker diseaseGeneticPathologyData availabilityThe datasets used and analyze...
Spatio-temporal brain invasion pattern of Streptococcus pneumoniae and dynamic changes in the cellular environment in bacteremia-derived meningitis
Spatio-temporal brain invasion pattern of Streptococcus pneumoniae and dynamic changes in the cellular environment in bacteremia-derived meningitis
Streptococcus pneumoniae (the pneumococcus) is the major cause of bacterial meningitis globally, and pneumococcal meningit...
Phenotypic analysis of multielectrode array EEG biomarkers in developing and adult male Fmr1 KO mice
Phenotypic analysis of multielectrode array EEG biomarkers in developing and adult male Fmr1 KO mice
KeywordsFragile X syndromeAutism spectrum disordersElectroencephalographyBiomarkerAuditory cortexSensory hypersensitivityE...
CHCHD10S59L/+ mouse model: Behavioral and neuropathological features of frontotemporal dementia
CHCHD10S59L/+ mouse model: Behavioral and neuropathological features of frontotemporal dementia
KeywordsCHCHD10MitochondrionFrontotemporal dementiaAmyotrophic lateral sclerosisMouse modelAbbreviationsIba1Actin-binding ...
Gut-brain axis in the pathogenesis of sepsis-associated encephalopathy
Gut-brain axis in the pathogenesis of sepsis-associated encephalopathy
KeywordsGut-brain axisSepsis-associated encephalopathyVagus nerveNeuroendocrineNeuroimmuneAbbreviationsACTHadrenocorticotr...
Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy
Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy
KeywordsAminoacyl-tRNA synthetase (ARS)Charcot-Marie-tooth disease (CMT)Intravital imagingMotor neuronNeuromuscular juncti...
Corrigendum to “Upregulation of tripeptidyl-peptidase 1 by 3-hydroxy-(2,2)-dimethyl butyrate, a brain endogenous ligand of PPARα: Implications for late-infantile Batten disease therapy” [Neurobiology of Disease 127 (2019) 362–373]
Corrigendum to “Upregulation of tripeptidyl-peptidase 1 by 3-hydroxy-(2,2)-dimethyl butyrate, a brain endogenous ligand of PPARα: Implications for late-infantile Batten disease therapy” [Neurobiology of Disease 127 (2019) 362–373]
Volume 194, May 2024, 106479Author links open overlay panelSudipta Chakrabarti a, Sujyoti Chandra a, Avik Roy a b, Madhuch...
Corrigendum to “Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy” [Neurobiology of Disease 136 (2020) 104715]
Corrigendum to “Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy” [Neurobiology of Disease 136 (2020) 104715]
Volume 194, May 2024, 106480Author links open overlay panelLi-Tao Yi a b c, Shu-Qi Dong a, Shuang-Shuang Wang a, Min Chen ...
Aberrant dynamic functional network connectivity in progressive supranuclear palsy
Aberrant dynamic functional network connectivity in progressive supranuclear palsy
KeywordsProgressive supranuclear palsyDynamic functional network connectivityCerebellum networkDefault mode networkSubcort...
Investigation of microglial diversity in a LRRK2 G2019S mouse model of Parkinson's disease
Investigation of microglial diversity in a LRRK2 G2019S mouse model of Parkinson's disease
Microglia contribute to the outcomes of various pathological conditions including Parkinson's disease (PD). Microglia are ...
Auditory oddball responses in the human subthalamic nucleus and substantia nigra pars reticulata
Auditory oddball responses in the human subthalamic nucleus and substantia nigra pars reticulata
KeywordsSTNSNrOddballNoveltySurpriseAttentionMicro electrode recordingDBSParkinson's diseaseAbbreviationsSNrSubstantia Nig...
Progressive alterations in polysomal architecture and activation of ribosome stalling relief factors in a mouse model of Huntington's disease
Progressive alterations in polysomal architecture and activation of ribosome stalling relief factors in a mouse model of Huntington's disease
Given their highly polarized morphology and functional singularity, neurons require precise spatial and temporal control o...
Spatial omics reveals molecular changes in focal cortical dysplasia type II
Spatial omics reveals molecular changes in focal cortical dysplasia type II
Focal cortical dysplasia (FCD) represents a group of diverse localized cortical lesions that are highly epileptogenic and ...
Phenotypical, genotypical and pathological characterization of the moonwalker mouse, a model of ataxia
Phenotypical, genotypical and pathological characterization of the moonwalker mouse, a model of ataxia
We performed a comprehensive study of the morphological, functional, and genetic features of moonwalker (MWK) mice, a mous...
Sex-specific vulnerabilities in human astrocytes underpin the differential impact of palmitic acid
Sex-specific vulnerabilities in human astrocytes underpin the differential impact of palmitic acid
Obesity and neurometabolic diseases have been linked to neurodegenerative diseases. Our hypothesis is that the endogenous ...
Proteomics insights into fragile X syndrome: Unraveling molecular mechanisms and therapeutic avenues
Proteomics insights into fragile X syndrome: Unraveling molecular mechanisms and therapeutic avenues
Fragile X Syndrome (FXS) is a neurodevelopment disorder characterized by cognitive impairment, behavioral challenges, and ...
A nonlinear meccano for Alzheimer's emergence by amyloid β-mediated glutamatergic hyperactivity
A nonlinear meccano for Alzheimer's emergence by amyloid β-mediated glutamatergic hyperactivity
Volume 194, May 2024, 106473Author links open overlay panel, , , , , , , Highlights•The amyloid β-mediated vicious cycle o...
Hippocampal Pyk2 regulates specific social skills: Implications for schizophrenia
Hippocampal Pyk2 regulates specific social skills: Implications for schizophrenia
Pyk2 has been shown previously to be involved in several psychological and cognitive alterations related to stress, Huntin...
Parvalbumin neurons in the nucleus accumbens shell modulate seizure in temporal lobe epilepsy
Parvalbumin neurons in the nucleus accumbens shell modulate seizure in temporal lobe epilepsy
A growing number of clinical and animal studies suggest that the nucleus accumbens (NAc), especially the shell, is involve...
Impaired olfactory identification in dementia-free individuals is associated with the functional abnormality of the precuneus
Impaired olfactory identification in dementia-free individuals is associated with the functional abnormality of the precuneus
ObjectiveOlfactory dysfunction indicates a higher risk of developing dementia. However, the potential structural and funct...
Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation
Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation
KeywordsEngrailed 1dopaminergic neuronprimary ciliaWnt signalinginduced pluripotent stem cellscomplex Imitochondrial respi...
Deciphering the shift from benign to active relapsing-remitting multiple sclerosis: Insights into T regulatory cell dysfunction and apoptosis regulation
Deciphering the shift from benign to active relapsing-remitting multiple sclerosis: Insights into T regulatory cell dysfunction and apoptosis regulation
BackgroundRelapsing-remitting multiple sclerosis (RRMS), a common demyelinating disease among young adults, follows a beni...
Corrigendum to “Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease” [Neurobiology of Disease, 2024 Jan:190:106376]
Corrigendum to “Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease” [Neurobiology of Disease, 2024 Jan:190:106376]
Volume 193, April 2024, 106444Author links open overlay panelStefan Bartl a 1, Yuanyun Xie b c, Nalini Potluri b, Ratnesh ...
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