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Physiologically Based Pharmacokinetic Modeling to Simulate CYP3A4-Mediated Drug-Drug Interactions for Pyrotinib
Physiologically Based Pharmacokinetic Modeling to Simulate CYP3A4-Mediated Drug-Drug Interactions for Pyrotinib
Pyrotinib is a newly developed tyrosine kinase inhibitor whose in vivo clearance relies heavily on cytochrome P450 3A4 (CY...
Perspectives and Considerations of IABP in the Era of ECMO for Cardiogenic Shock
Perspectives and Considerations of IABP in the Era of ECMO for Cardiogenic Shock
The development of mechanical circulatory support (MCS) has been rapid, and its use worldwide in patients with cardiogenic...
Clinical Performance of New Enhanced Monofocal Intraocular Lenses: Comparison of Hydrophobic C-loop and Hydrophilic Plate-Haptic Platform
Clinical Performance of New Enhanced Monofocal Intraocular Lenses: Comparison of Hydrophobic C-loop and Hydrophilic Plate-Haptic Platform
Enhanced monofocal intraocular lenses (IOLs) represent a new type of lens, which should lead to a very good distance visio...
Greenhouse Gas Emissions from Respiratory Treatments: Results from the SABA CARBON International Study
Greenhouse Gas Emissions from Respiratory Treatments: Results from the SABA CARBON International Study
Healthcare systems are looking to reduce their carbon impact. Short-acting β2-agonist (SABA) overuse (≥ 3...
Unmet Needs in the Treatment of Childhood Type 2 Diabetes: A Narrative Review
Unmet Needs in the Treatment of Childhood Type 2 Diabetes: A Narrative Review
Type 2 diabetes (T2D) in youth is a global health concern characterized by an increasing incidence and prevalence, especia...
Narrative Review of Topiramate: Clinical Uses and Pharmacological Considerations
Narrative Review of Topiramate: Clinical Uses and Pharmacological Considerations
Due to the diverse mechanisms of action of antiseizure drugs, there has been a rise in prescriptions of these drugs for no...
A Podcast Discussion on the Current Treatment Landscape for Renal Cell Carcinoma
A Podcast Discussion on the Current Treatment Landscape for Renal Cell Carcinoma
During the last 15 years, tremendous efforts have been made in the medical treatment of metastatic renal cell car...
First Line Medical Treatment of Metastatic Renal Cell Carcinoma: A Podcast on Choosing Wisely and Managing Safely
First Line Medical Treatment of Metastatic Renal Cell Carcinoma: A Podcast on Choosing Wisely and Managing Safely
During the last 15 years, tremendous efforts have been made toward medical treatment of metastatic renal cell car...
Application of Autologous Hair Transplantation Technique in Children with Cicatricial Alopecia
Application of Autologous Hair Transplantation Technique in Children with Cicatricial Alopecia
Cicatricial alopecia not only affects the appearance of children's heads and faces but also their mental health in the...
Budget Impact Analysis of Expanding Gliflozin Coverage in the CKD Population: A French Perspective
Budget Impact Analysis of Expanding Gliflozin Coverage in the CKD Population: A French Perspective
Gliflozins have historically been indicated for type 2 diabetes in France. However, their efficacy has recently been demon...
Efficacy and Safety of Pirfenidone in Advanced Versus Non-Advanced Idiopathic Pulmonary Fibrosis: Post-Hoc Analysis of Six Clinical Studies
Efficacy and Safety of Pirfenidone in Advanced Versus Non-Advanced Idiopathic Pulmonary Fibrosis: Post-Hoc Analysis of Six Clinical Studies
In the European Union (EU), the indication for the antifibrotic pirfenidone prior to April 2023 did not include patients w...