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Gene of the month: ERG
Gene of the month: ERG
The ERG gene belongs to the erythroblastosis transformation specific family of transcription factors and encodes for the t...
PTEN as a target in melanoma
PTEN as a target in melanoma
BackgroundMelanoma is the most fatal form of skin cancer, and mortality rates continue to increase. In the case of Austral...
Role of artificial intelligence and machine learning in haematology
Role of artificial intelligence and machine learning in haematology
IntroductionArtificial intelligence (AI) is conventionally defined as the ability of a computer system to perform tasks th...
Lights on HBME-1: the elusive biomarker in thyroid cancer pathology
Lights on HBME-1: the elusive biomarker in thyroid cancer pathology
Among the different ancillary immunohistochemical tools that pathologists may employ in thyroid nodules, the so-called Hec...
Auxiliary diagnostic value of D2-40 in early lung adenocarcinoma and precursor lesions
Auxiliary diagnostic value of D2-40 in early lung adenocarcinoma and precursor lesions
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Adipophilin expression in skin lesions with clear cell histology
Adipophilin expression in skin lesions with clear cell histology
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Rapid serum clot tubes reduce haemolysis due to pneumatic tube transport
Rapid serum clot tubes reduce haemolysis due to pneumatic tube transport
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Novel pooling strategy with sample concentration for screening of SARS-CoV-2
Novel pooling strategy with sample concentration for screening of SARS-CoV-2
Reverse transcription PCR (RT-PCR) is the gold standard for rapidly confirming infection with SARS-CoV-2. However, the gre...
Gene of the month: Cornulin
Gene of the month: Cornulin
IntroductionCornulin gene and structureThe gene encoding Cornulin (CRNN) is present on the first chromosome at position 1q...
Clinicopathological predictors of survival in resected primary lung adenocarcinoma
Clinicopathological predictors of survival in resected primary lung adenocarcinoma
IntroductionLung cancer is the leading cause of cancer-related mortality worldwide, with adenocarcinoma being the most com...
Comparison between 1973 and 2004/2016 WHO grading systems in patients with Ta urothelial carcinoma of urinary bladder
Comparison between 1973 and 2004/2016 WHO grading systems in patients with Ta urothelial carcinoma of urinary bladder
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CXCR4/ACKR3/CXCL12 axis in the lymphatic metastasis of vulvar squamous cell carcinoma
CXCR4/ACKR3/CXCL12 axis in the lymphatic metastasis of vulvar squamous cell carcinoma
IntroductionVulvar squamous cell carcinoma (VSCC) is a rare disease accounting for about 4% of all gynecological malignanc...
Core needle biopsy wash as a tool for acquiring additional diagnostic material for laboratory testing
Core needle biopsy wash as a tool for acquiring additional diagnostic material for laboratory testing
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Rapid EGFR evaluation from used H&E, IHC and FISH diagnostic slides with the Idylla platform
Rapid EGFR evaluation from used H&E, IHC and FISH diagnostic slides with the Idylla platform
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Conjunctival squamous intraepithelial neoplasia and its differential diagnosis
Conjunctival squamous intraepithelial neoplasia and its differential diagnosis
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Impact of the COVID-19 pandemic on cytopathology services in the West of Ireland
Impact of the COVID-19 pandemic on cytopathology services in the West of Ireland
The COVID-19 pandemic arose from global transmission of the novel coronavirus SARS-CoV-2 which is thought to have originat...
Correction: Towards better understanding of giant cell granulomas of the oral cavity
Correction: Towards better understanding of giant cell granulomas of the oral cavity
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Correction: Pathology of IgG4-related sclerosing mastitis
Correction: Pathology of IgG4-related sclerosing mastitis
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Genes of the month: H3.3 histone genes: H3F3A and H3F3B
Genes of the month: H3.3 histone genes: H3F3A and H3F3B
IntroductionHistones are basic nuclear proteins that act as architectural scaffolds for the compaction of double-stranded ...
Cancer-associated fibroblasts (CAFs) in thyroid papillary carcinoma: molecular networks and interactions
Cancer-associated fibroblasts (CAFs) in thyroid papillary carcinoma: molecular networks and interactions
In 1989, Stephen Paget proposed the ‘seed and soil’ theory of cancer metastasis. This theory has led to previous researche...