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Common functional connectivity alterations in focal epilepsies identified by machine learning
Common functional connectivity alterations in focal epilepsies identified by machine learning
Abstract Objective This study was undertaken to identify shared functional network characteristics among focal epilepsies ...
Deep brain stimulation targets in epilepsy: Systematic review and meta‐analysis of anterior and centromedian thalamic nuclei and hippocampus
Deep brain stimulation targets in epilepsy: Systematic review and meta‐analysis of anterior and centromedian thalamic nuclei and hippocampus
Abstract Deep brain stimulation (DBS) is a neuromodulatory treatment used in patients with drug-resistant epilepsy (DRE). ...
Survey on the worldwide availability and affordability of antiseizure medications: Report of the ILAE Task Force on Access to Treatment
Survey on the worldwide availability and affordability of antiseizure medications: Report of the ILAE Task Force on Access to Treatment
Summary Health systems worldwide are challenged in the provision of basic medical services and access to treatments for ch...
Pediatric Epilepsy Learning Healthcare System Quality of Life (PELHS‐QOL‐2): A novel health‐related quality of life prompt for children with epilepsy
Pediatric Epilepsy Learning Healthcare System Quality of Life (PELHS‐QOL‐2): A novel health‐related quality of life prompt for children with epilepsy
Abstract Objective Pediatric epilepsy is often associated with diminished health-related quality of life (HRQOL). Our aim ...
Economic evaluation of deep brain stimulation compared with vagus nerve stimulation and usual care for patients with refractory epilepsy: A lifetime decision analytic model
Economic evaluation of deep brain stimulation compared with vagus nerve stimulation and usual care for patients with refractory epilepsy: A lifetime decision analytic model
Abstract Objectives This study was undertaken to estimate the cost-effectiveness of deep brain stimulation (DBS) compared ...
Adults with tuberous sclerosis complex: A distinct patient population
Adults with tuberous sclerosis complex: A distinct patient population
Abstract Objectives There are few data on adults living with tuberous sclerosis complex (TSC), with most studies focusing ...
Not your usual drug‐drug interactions: Monoclonal antibody–based therapeutics may interact with antiseizure medications
Not your usual drug‐drug interactions: Monoclonal antibody–based therapeutics may interact with antiseizure medications
Abstract Therapeutic monoclonal antibodies (mAbs) have emerged as the fastest growing drug class. As such, mAbs are increa...
Mutations associated with epileptic encephalopathy modify EAAT2 anion channel function
Mutations associated with epileptic encephalopathy modify EAAT2 anion channel function
Abstract Objective Mutations in the gene solute carrier family member 1A2 (SLC1A2) encoding the excitatory amino acid tran...
Long‐term cannabidiol treatment for seizures in patients with tuberous sclerosis complex: An open‐label extension trial
Long‐term cannabidiol treatment for seizures in patients with tuberous sclerosis complex: An open‐label extension trial
Abstract Objective To evaluate the long-term safety and efficacy of add-on cannabidiol (CBD) in patients with seizures ass...
Norwegian population‐based study of long‐term effects, safety, and predictors of response of vagus nerve stimulation treatment in drug‐resistant epilepsy: The NORPulse study
Norwegian population‐based study of long‐term effects, safety, and predictors of response of vagus nerve stimulation treatment in drug‐resistant epilepsy: The NORPulse study
Abstract Objective This study was undertaken to evaluate the efficacy of vagus nerve stimulation (VNS) over time, and to d...
Association between antiseizure medications and quality of life in epilepsy: A mediation analysis
Association between antiseizure medications and quality of life in epilepsy: A mediation analysis
Abstract Objective The relationship between antiseizure medications (ASMs), which improve health outcomes by controlling s...
Thank you to our Reviewers
Thank you to our Reviewers
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Correcting for physiological ripples improves epileptic focus identification and outcome prediction
Correcting for physiological ripples improves epileptic focus identification and outcome prediction
Abstract Objective The integration of high-frequency oscillations (HFOs; ripples [80–250 Hz], fast ripples [25...
Early alterations of the neuronal network processing whisker‐related sensory signal during absence epileptogenesis
Early alterations of the neuronal network processing whisker‐related sensory signal during absence epileptogenesis
Abstract Objective Epileptogenesis is the particular process during which the epileptic network builds up progressively be...
Relative importance of clinical outcomes and safety risks of antiseizure medication monotherapy for patients and physicians: Discrete choice experiment eliciting preferences in real‐world study "VOTE"
Relative importance of clinical outcomes and safety risks of antiseizure medication monotherapy for patients and physicians: Discrete choice experiment eliciting preferences in real‐world study "VOTE"
Abstract Objective This study was undertaken to elicit patients' preferences for attributes characterizing antiseizure med...
Increased expression of complement components in tuberous sclerosis complex and focal cortical dysplasia type 2B brain lesions
Increased expression of complement components in tuberous sclerosis complex and focal cortical dysplasia type 2B brain lesions
Abstract Objective Increasing evidence supports the contribution of inflammatory mechanisms to the neurological manifestat...
Minimum standards for inpatient long‐term video‐electroencephalographic monitoring: A clinical practice guideline of the International League Against Epilepsy and International Federation of Clinical Neurophysiology
Minimum standards for inpatient long‐term video‐electroencephalographic monitoring: A clinical practice guideline of the International League Against Epilepsy and International Federation of Clinical Neurophysiology
Summary The objective of this clinical practice guideline is to provide recommendations on the indications and minimum sta...
Accelerated long‐term forgetting in adult patients with genetic generalized epilepsy
Accelerated long‐term forgetting in adult patients with genetic generalized epilepsy
Abstract Objective Accelerated long-term forgetting (ALF) has been demonstrated among children but not adults with genetic...
Genetic testing for the epilepsies: A systematic review
Genetic testing for the epilepsies: A systematic review
Abstract Objective Numerous genetic testing options for individuals with epilepsy have emerged over the past decade withou...
Epilepsia – December 2021 – Announcements
Epilepsia – December 2021 – Announcements
OTHER CONGRESSES 3–7 December 2021 AES Annual Meeting ...
Abnormal functional connectivity profiles predict drug responsiveness in patients with temporal lobe epilepsy
Abnormal functional connectivity profiles predict drug responsiveness in patients with temporal lobe epilepsy
Abstract Objective This work was undertaken to study the functional connectivity differences between non-seizure-free and ...
ILAE clinical practice recommendations for the medical treatment of depression in adults with epilepsy
ILAE clinical practice recommendations for the medical treatment of depression in adults with epilepsy
Abstract The aim of this document is to provide evidence-based recommendations for the medical treatment of depression in ...
“Do I still have epilepsy?” Epilepsy identity 15–20 years after anterior temporal lobectomy
“Do I still have epilepsy?” Epilepsy identity 15–20 years after anterior temporal lobectomy
Abstract Objective Identity is a multifaceted construct, comprising personal identity (sense of being a unique individual)...
Low prevalence of amyloid and tau pathology in drug‐resistant temporal lobe epilepsy
Low prevalence of amyloid and tau pathology in drug‐resistant temporal lobe epilepsy
Abstract Objective Cognitive impairment is common in patients with chronic drug-resistant temporal lobe epilepsy (TLE). Hy...
Influences on the trajectory and subsequent outcomes in CDKL5 deficiency disorder
Influences on the trajectory and subsequent outcomes in CDKL5 deficiency disorder
Abstract Objective The study investigated the effect of seizure and medication burden at initial contact with the Internat...
Effects of laser interstitial thermal therapy for mesial temporal lobe epilepsy on the structural connectome and its relationship to seizure freedom
Effects of laser interstitial thermal therapy for mesial temporal lobe epilepsy on the structural connectome and its relationship to seizure freedom
Summary Objective Laser interstitial thermal therapy (LITT) is a minimally invasive surgery for mesial temporal lobe epile...
Rasmussen encephalitis: Predisposing factors and their potential role in unilaterality
Rasmussen encephalitis: Predisposing factors and their potential role in unilaterality
Abstract Objective Rasmussen encephalitis (RE) is a progressive and destructive inflammatory disease of one hemisphere. It...
Simulated driving in the epilepsy monitoring unit: Effects of seizure type, consciousness, and motor impairment
Simulated driving in the epilepsy monitoring unit: Effects of seizure type, consciousness, and motor impairment
Abstract People with epilepsy face serious driving restrictions, determined using retrospective studies. To relate seizure...
Long‐term individual retention with cenobamate in adults with focal seizures: Pooled data from the clinical development program
Long‐term individual retention with cenobamate in adults with focal seizures: Pooled data from the clinical development program
Abstract Objective We determined retention on open-label cenobamate therapy in the clinical development program to assess ...
COVID‐19 vaccine take‐up rate and safety in adults with epilepsy: Data from a multicenter study in China
COVID‐19 vaccine take‐up rate and safety in adults with epilepsy: Data from a multicenter study in China
Summary Objective This study was undertaken to investigate the COVID-19 vaccine uptake rate and possible postvaccination e...
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