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The regulation of Tfh cell differentiation by β-hydroxybutyrylation modification of transcription factor Bcl6
The regulation of Tfh cell differentiation by β-hydroxybutyrylation modification of transcription factor Bcl6
Transcriptional repressor B cell lymphoma 6 (Bcl6) is a major transcription factor involved in Tfh cell differentiation an...
Modeling of covalent modifications of histones to estimate the binding affinity
Modeling of covalent modifications of histones to estimate the binding affinity
Covalent histone modifications such as methylation, acetylation, phosphorylation, and other epigenetic modifications of th...
Regulation of the epigenome through RNA modifications
Regulation of the epigenome through RNA modifications
Chemical modifications of nucleotides expand the complexity and functional properties of genomes and transcriptomes. A han...
Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors
Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors
The chromosomal cohesin complex establishes sister chromatid cohesion during S phase, which forms the basis for faithful s...
Using Synthetic DNA Libraries to Investigate Chromatin and Gene Regulation
Using Synthetic DNA Libraries to Investigate Chromatin and Gene Regulation
Despite the recent explosion in genome-wide studies in chromatin and gene regulation, we are still far from extracting a s...
Fluorescence-based super-resolution-microscopy strategies for chromatin studies
Fluorescence-based super-resolution-microscopy strategies for chromatin studies
Super-resolution microscopy (SRM) is a prime tool to study chromatin organisation at near biomolecular resolution in the n...
A cytological revisit on parthenogenetic Artemia and the deficiency of a meiosis-specific recombinase DMC1 in the possible transition from bisexuality to parthenogenesis
A cytological revisit on parthenogenetic Artemia and the deficiency of a meiosis-specific recombinase DMC1 in the possible transition from bisexuality to parthenogenesis
Although parthenogenesis is widespread in nature and known to have close relationships with bisexuality, the transitional ...
Establishment and inheritance of minichromosomes from Arabidopsis haploid induction
Establishment and inheritance of minichromosomes from Arabidopsis haploid induction
Minichromosomes are small, sometimes circular, rearranged chromosomes consisting of one centromere and short chromosomal a...
Are extraordinary nucleosome structures more ordinary than we thought?
Are extraordinary nucleosome structures more ordinary than we thought?
The nucleosome is a DNA–protein assembly that is the basic unit of chromatin. A nucleosome can adopt various structu...
The launch of satellite: DNA repeats as a cytogenetic tool in discovering the chromosomal universe of wild Triticeae
The launch of satellite: DNA repeats as a cytogenetic tool in discovering the chromosomal universe of wild Triticeae
Fluorescence in situ hybridization is a powerful tool that enables plant researchers to perform systematic, evolutionary, ...
A genome-wide RNAi screen for genes important for proliferation of cultured Drosophila cells at low temperature identifies the Ball/VRK protein kinase
A genome-wide RNAi screen for genes important for proliferation of cultured Drosophila cells at low temperature identifies the Ball/VRK protein kinase
A change in ambient temperature is predicted to disrupt cellular homeostasis by affecting all cellular processes in an alb...
Super-resolution microscopy reveals the number and distribution of topoisomerase IIα and CENH3 molecules within barley metaphase chromosomes
Super-resolution microscopy reveals the number and distribution of topoisomerase IIα and CENH3 molecules within barley metaphase chromosomes
Topoisomerase IIα (Topo IIα) and the centromere-specific histone H3 variant CENH3 are key proteins involved in c...
Sex-chrom v. 2.0: a database of green plant species with sex chromosomes
Sex-chrom v. 2.0: a database of green plant species with sex chromosomes
Baránková S, Pascual-Díaz JP, Sultana N et al (2020) Sex-chrom, a database on plant sex chromosomes. New Phytol 227:1594–1...
A large-scale RNAi screen reveals that mitochondrial function is important for meiotic chromosome organization in oocytes
A large-scale RNAi screen reveals that mitochondrial function is important for meiotic chromosome organization in oocytes
In prophase of the first meiotic division, chromatin forms a compact spherical cluster called the karyosome within the enl...
A step forward in the genome characterization of the sugarcane borer, Diatraea saccharalis: karyotype analysis, sex chromosome system and repetitive DNAs through a cytogenomic approach
A step forward in the genome characterization of the sugarcane borer, Diatraea saccharalis: karyotype analysis, sex chromosome system and repetitive DNAs through a cytogenomic approach
Moths of the family Crambidae include a number of pests that cause economic losses to agricultural crops. Despite their ec...
Cytogenetic status of patients with congenital malformations or suspected chromosomal abnormalities in Turkey: a comprehensive cytogenetic survey of 11,420 patients
Cytogenetic status of patients with congenital malformations or suspected chromosomal abnormalities in Turkey: a comprehensive cytogenetic survey of 11,420 patients
Cytogenetic analysis is helpful in diagnostic workup of patients having prenatal or early postnatal medical problems and p...
Comparison of the somatic TADs and lampbrush chromomere-loop complexes in transcriptionally active prophase I oocytes
Comparison of the somatic TADs and lampbrush chromomere-loop complexes in transcriptionally active prophase I oocytes
In diplotene oocyte nuclei of all vertebrate species, except mammals, chromosomes lack interchromosomal contacts and chrom...
Genome characterization and CRISPR-Cas9 editing of a human neocentromere
Genome characterization and CRISPR-Cas9 editing of a human neocentromere
The maintenance of genome integrity is ensured by proper chromosome inheritance during mitotic and meiotic cell divisions....
Time to match; when do homologous chromosomes become closer?
Time to match; when do homologous chromosomes become closer?
In most eukaryotes, pairing of homologous chromosomes is an essential feature of meiosis that ensures homologous recombina...
The spectrum of chromosomal translocations in the Arab world: ethnic-specific chromosomal translocations and their relevance to diseases
The spectrum of chromosomal translocations in the Arab world: ethnic-specific chromosomal translocations and their relevance to diseases
Chromosomal translocations (CTs) are the most common type of structural chromosomal abnormalities in humans. CTs have been...
Transcription factor Sp1 regulates mitotic chromosome assembly and segregation
Transcription factor Sp1 regulates mitotic chromosome assembly and segregation
Aneuploidy is a pervasive feature of cancer cells that results from chromosome missegregation. Several transcription facto...
Migration of repetitive DNAs during evolution of the permanent translocation heterozygosity in the oyster plant (Tradescantia section Rhoeo)
Migration of repetitive DNAs during evolution of the permanent translocation heterozygosity in the oyster plant (Tradescantia section Rhoeo)
Due to translocation heterozygosity for all chromosomes in the cell complement, the oyster plant (Tradescantia spathacea) ...
Allele segregation analysis of F1 hybrids between independent Brassica allohexaploid lineages
Allele segregation analysis of F1 hybrids between independent Brassica allohexaploid lineages
In the Brassica genus, we find both diploid species (one genome) and allotetraploid species (two different genomes) but no...
Life of double minutes: generation, maintenance, and elimination
Life of double minutes: generation, maintenance, and elimination
Advances in genome sequencing have revealed a type of extrachromosomal DNA, historically named double minutes (also referr...
Kinesin-5 Eg5 mediates centrosome separation to control spindle assembly in spermatocytes
Kinesin-5 Eg5 mediates centrosome separation to control spindle assembly in spermatocytes
Timely and accurate centrosome separation is critical for bipolar spindle organization and faithful chromosome segregation...
Germline-restricted chromosome shows remarkable variation in size among closely related passerine species
Germline-restricted chromosome shows remarkable variation in size among closely related passerine species
Passerine birds have a supernumerary chromosome in their germ cells called the germline-restricted chromosome (GRC). The G...
Multiple heterochromatin diversification events in the genome of fungus-farming ants: insights from repetitive sequences
Multiple heterochromatin diversification events in the genome of fungus-farming ants: insights from repetitive sequences
A substantial portion of the eukaryotic genome includes repetitive DNA, which is important for its stability, regulation, ...
The N-terminal domain of TET1 promotes the formation of dense chromatin regions refractory to transcription
The N-terminal domain of TET1 promotes the formation of dense chromatin regions refractory to transcription
TET (ten-eleven translocation) enzymes initiate active cytosine demethylation via the oxidation of 5-methylcytosine. TET1 ...
Satellitome analysis illuminates the evolution of ZW sex chromosomes of Triportheidae fishes (Teleostei: Characiformes)
Satellitome analysis illuminates the evolution of ZW sex chromosomes of Triportheidae fishes (Teleostei: Characiformes)
Satellites are an abundant source of repetitive DNAs that play an essential role in the chromosomal organization and are t...
NucPosDB: a database of nucleosome positioning in vivo and nucleosomics of cell-free DNA
NucPosDB: a database of nucleosome positioning in vivo and nucleosomics of cell-free DNA
Nucleosome positioning is involved in many gene regulatory processes happening in the cell, and it may change as cells dif...
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