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A narrative review on bacterial biofilm: its formation, clinical aspects and inhibition strategies
A narrative review on bacterial biofilm: its formation, clinical aspects and inhibition strategies
The predominant mode of life of most of the bacteria is their biofilm state. Based on the type of bacteria existi...
The phytochemical screening, total cucurbitacin content, and in vitro anti-breast cancer activity of Leucopaxillus gentianeus mushroom
The phytochemical screening, total cucurbitacin content, and in vitro anti-breast cancer activity of Leucopaxillus gentianeus mushroom
The popular Leucopaxillus gentianeus mushroom contains very high nutrients and bioactive compounds with good anti-breast c...
New analytical LC–MS/MS method for fluconazole and ivermectin estimation in combined pharmaceutical dosage form: development and validation
New analytical LC–MS/MS method for fluconazole and ivermectin estimation in combined pharmaceutical dosage form: development and validation
Fluconazole, an antifungal drug, prevents fungi growth by inhibiting the formation of a protective covering. Ivermectin ha...
Development and validation of ICPMS methods for simultaneous determination of elemental impurities in topical cream containing ximenynic acid
Development and validation of ICPMS methods for simultaneous determination of elemental impurities in topical cream containing ximenynic acid
These days, the presence of simple impurities in pharmaceuticals is a major cause for worry. This is because some contamin...
Development and validation of a stability-indicating RP-HPLC method for estimation of Lefamulin in pure and pharmaceutical drug products
Development and validation of a stability-indicating RP-HPLC method for estimation of Lefamulin in pure and pharmaceutical drug products
Commonly occurring serious lung parenchymal infection is community-acquired bacterial pneumonia (CABP). Lefamulin acetate ...
Synthesis of biologically active sulfonamide-based indole analogs: a review
Synthesis of biologically active sulfonamide-based indole analogs: a review
The class of heterocyclic compounds exhibits a variety of pharmacological actions, long employed as an active ingredient i...
Anticancer potential of algae-derived metabolites: recent updates and breakthroughs
Anticancer potential of algae-derived metabolites: recent updates and breakthroughs
Cancer is an increasing medical condition that poses a threat to worldwide populations, despite improvements in scientific...
Design, development, and evaluation of docetaxel-loaded niosomes for the treatment of breast cancer
Design, development, and evaluation of docetaxel-loaded niosomes for the treatment of breast cancer
Docetaxel (DTX) has been used to treat numerous types of cancers. Poor solubility, lower bioavailability, and serious side...
Emerging therapeutic potential of curcumin in the management of dermatological diseases: an extensive review of drug and pharmacological activities
Emerging therapeutic potential of curcumin in the management of dermatological diseases: an extensive review of drug and pharmacological activities
Curcumin is a bright colored polyphenolic moiety which is derived from the rhizomes of Curcuma longa of family Zingiberace...
Evaluation of cardiopreventive effects of Ximenia americana (Linn.) and Pappea capensis (Eckl. and Zeyh.) leaf aqueous extracts in rat models with myocardial infarction
Evaluation of cardiopreventive effects of Ximenia americana (Linn.) and Pappea capensis (Eckl. and Zeyh.) leaf aqueous extracts in rat models with myocardial infarction
Myocardial infarction is a significant health issue in both wealthy and underdeveloped nations. Globally, it is the leadin...
Evaluation of anti-atherosclerotic potential of Tinospora cordifolia in high-fat diet-induced atherosclerosis with associated changes in histological and biochemical parameters on Wistar rats
Evaluation of anti-atherosclerotic potential of Tinospora cordifolia in high-fat diet-induced atherosclerosis with associated changes in histological and biochemical parameters on Wistar rats
Atherosclerosis is a chronic inflammatory disease. Atherosclerosis starts with fatty streak which is an accumulation of li...
Crinum jagus: antiproliferative studies of extracts on HepG2 cell line and in silico assessment of phytoconstituents as potential inhibitors of p53–mortalin interaction
Crinum jagus: antiproliferative studies of extracts on HepG2 cell line and in silico assessment of phytoconstituents as potential inhibitors of p53–mortalin interaction
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide and has a poor prognosis in black Afri...
Identification of effective plant extracts against candidiasis: an in silico and in vitro approach
Identification of effective plant extracts against candidiasis: an in silico and in vitro approach
Globally, millions of people suffer from repeated fungal infections affecting the skin, keratinized tissues, and mucosal m...
The design and evaluation of ciprofloxacin-loaded nanoformulations using Ipomoea batatas starch nanoparticles
The design and evaluation of ciprofloxacin-loaded nanoformulations using Ipomoea batatas starch nanoparticles
Starch nanoparticle derivatives are gaining popularity as drug delivery vehicles because of their biocompatibility, better...
In vitro characterization of self-emulsifying drug delivery system-based lipsticks loaded with ketoconazole
In vitro characterization of self-emulsifying drug delivery system-based lipsticks loaded with ketoconazole
Self-emulsifying system-based lipstick may prove to have the potential of enhancing moisturizing characteristics and deliv...
HPLC fingerprint of flavonoids, enzyme inhibition and antioxidant activity of Newbouldia laevis stem-bark: an in vitro and in silico study
HPLC fingerprint of flavonoids, enzyme inhibition and antioxidant activity of Newbouldia laevis stem-bark: an in vitro and in silico study
Medicinal plant contains multiple bioactive compounds with therapeutic potentials. Due to their availability, affordabilit...
Chlorzoxazone reduced the paracetamol-induced toxicity via competitive inhibition of CYP2E1-mediated metabolism
Chlorzoxazone reduced the paracetamol-induced toxicity via competitive inhibition of CYP2E1-mediated metabolism
Drug metabolism is crucial to attaining the therapeutic index of any drug. The metabolism and elimination of the drugs are...
Mosquito larvicidal, pupicidal and ovidical effects of the different extracts of the leaves of Peltophorum pterocarpum against Aedes aegypti and Culex quinquefasciatus
Mosquito larvicidal, pupicidal and ovidical effects of the different extracts of the leaves of Peltophorum pterocarpum against Aedes aegypti and Culex quinquefasciatus
Mosquitoes are vectors for several diseases like dengue, chikingunea, malaria etc. The three important mosquito species in...
Neuro-nutraceuticals: Insights of experimental evidences and molecular mechanism in neurodegenerative disorders
Neuro-nutraceuticals: Insights of experimental evidences and molecular mechanism in neurodegenerative disorders
One of the most important healthcare challenges in the world today is neurological disorders. Pose lifestyle changes are l...
The promising guide to LC–MS analysis and cholinesterase activity of Luffa cylindrica (L.) fruit using in vitro and in-silico analyses
The promising guide to LC–MS analysis and cholinesterase activity of Luffa cylindrica (L.) fruit using in vitro and in-silico analyses
Luffa cylindrica (L.) is an annual climbing plant that produces fibrous fruit and can also be used as a vegetable in north...
Utilisation of Mangifera indica plant extracts and parts in antimicrobial formulations and as a pharmaceutical excipient: a review
Utilisation of Mangifera indica plant extracts and parts in antimicrobial formulations and as a pharmaceutical excipient: a review
Antimicrobial resistance and the environmental threat posed by some synthetic antimicrobial agents necessitate more resear...
Could eggshell membrane be an adjuvant for recombinant Hepatitis B vaccine?: A preliminary investigation
Could eggshell membrane be an adjuvant for recombinant Hepatitis B vaccine?: A preliminary investigation
Despite the invasiveness of the Hepatitis B infection, its vaccines are only formulated with FDA-approved alum-based adjuv...
Autoregulation: mediators and renin–angiotensin system in diseases and treatments
Autoregulation: mediators and renin–angiotensin system in diseases and treatments
Hemodynamic regulation is a substantial part of the physiological integrity of the human body. It is based on the delivery...
Naringenin alters the pharmacokinetics of ranolazine in part through the inhibition of cytochrome P450 (3A4) and P-glycoprotein
Naringenin alters the pharmacokinetics of ranolazine in part through the inhibition of cytochrome P450 (3A4) and P-glycoprotein
This study set out to look at how naringenin affected the pharmacokinetics of ranolazine in rats. The pharmacokinetic inve...
Antioxidant properties and cytotoxic effects of Oxalis corniculata on human Hepatocarcinoma (Hep-G2) cell line: an in vitro and in silico evaluation
Antioxidant properties and cytotoxic effects of Oxalis corniculata on human Hepatocarcinoma (Hep-G2) cell line: an in vitro and in silico evaluation
Oxalis corniculata is a well-known medicinal plant used in folk medicine for the management of many diseases. The aim is t...
Identification of an inhibitor for atherosclerotic enzyme NOX-1 to inhibit ROS production
Identification of an inhibitor for atherosclerotic enzyme NOX-1 to inhibit ROS production
NOX-1 overexpression has been observed in various studies, persons with diabetes or cardiovascular conditions. NOX-1 orche...
Development and validation of stability indicating HPLC–PDA method for the simultaneous determination of benzoyl peroxide and tretinoin in topical dosage form
Development and validation of stability indicating HPLC–PDA method for the simultaneous determination of benzoyl peroxide and tretinoin in topical dosage form
Acne vulgaris is a very dangerous skin disease leads to psychological disorders. Benzoyl peroxide and tretinoin in combina...
Genome-wide association study for single nucleotide polymorphism associated with mural and cumulus granulosa cells of PCOS (polycystic ovary syndrome) and non-PCOS patients
Genome-wide association study for single nucleotide polymorphism associated with mural and cumulus granulosa cells of PCOS (polycystic ovary syndrome) and non-PCOS patients
The genetic make-up of local granulosa cells and their function in the pathophysiology of polycystic ovary syndrome (PCOS)...
Prescribing patterns of thromboprophylaxis post-bariatric surgeries: no additional benefits of extended prophylaxis
Prescribing patterns of thromboprophylaxis post-bariatric surgeries: no additional benefits of extended prophylaxis
Venous thromboembolism is one of the critical complications of bariatric surgeries resulting in life-threatening outcomes....
Bioenhancers from mother nature: an overview
Bioenhancers from mother nature: an overview
The concept of bioenhancer comes from Ayurveda. Many ways have been documented in the literature to boost the bioavailabil...
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