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Stability indicating eco-friendly HPLC method development and validation for the estimation of bisoprolol fumarate and telmisartan
Stability indicating eco-friendly HPLC method development and validation for the estimation of bisoprolol fumarate and telmisartan
Telmisartan and bisoprolol fumarate together are two medications that diminish arterial pressure. The current study compri...
Abatement by Alhagi maurorum of lead-induced nephrotoxicity in rats: emphasis on Nrf2/HO-1
Abatement by Alhagi maurorum of lead-induced nephrotoxicity in rats: emphasis on Nrf2/HO-1
Lead (Pb) is a heavy metal with extreme toxicity and numerous industrial uses. It produces nephrotoxicity with notable cha...
Novel tetracycline hybrids: synthesis, characterization, docking studies and in-vitro evaluation of antibacterial activity
Novel tetracycline hybrids: synthesis, characterization, docking studies and in-vitro evaluation of antibacterial activity
The biggest menace in the world today is the infection caused by pathogenic bacteria in humans, where majority of the avai...
Biogenic nanotransferosomal vesicular system of Clerodendrum serratum L. for skin cancer therapy: formulation, characterization, and efficacy evaluation
Biogenic nanotransferosomal vesicular system of Clerodendrum serratum L. for skin cancer therapy: formulation, characterization, and efficacy evaluation
The pivotal intent of this study was to investigate the medicinal potential of synthesized nanotransferosomes utilizing Cl...
Synthesis and anti-microbial evaluation with in silico studies of novel 2-aminothiazole benzohydrazide derivatives
Synthesis and anti-microbial evaluation with in silico studies of novel 2-aminothiazole benzohydrazide derivatives
The development of novel anti-microbial drugs for multidrug-resistant (MDR) is a significant challenge. This study aimed t...
Phytochemical analysis and anti-aging efficacy of two Egyptian sweet potato cultivars in a d-galactose-induced skin aging model
Phytochemical analysis and anti-aging efficacy of two Egyptian sweet potato cultivars in a d-galactose-induced skin aging model
Sweet potato (Ipomoea batatas (L.) Lam.) is a member of the family Convolvulaceae. Much research has highlighted its varia...
Formulation and evaluation of hyaluronic acid and adipic acid dihydrazide modified graphene quantum dot-based nanotherapeutics for paclitaxel-targeted delivery in breast cancer
Formulation and evaluation of hyaluronic acid and adipic acid dihydrazide modified graphene quantum dot-based nanotherapeutics for paclitaxel-targeted delivery in breast cancer
Paclitaxel (PAC) was the first-ever natural chemotherapeutic agent for the treatment of breast cancer. However, it has som...
Molecular mechanisms and enhanced functions of Hibiscus sabdariffa L—nanoliposomes as an emerging therapeutic strategy in UV and galactosamine skin aging-induced model
Molecular mechanisms and enhanced functions of Hibiscus sabdariffa L—nanoliposomes as an emerging therapeutic strategy in UV and galactosamine skin aging-induced model
Skin aging is a multifactorial disorder that occurs due to extrinsic and intrinsic factors, where a decrease in natural an...
Unveiling the therapeutic potential of insect-derived natural products for drug discovery
Unveiling the therapeutic potential of insect-derived natural products for drug discovery
The recent FDA-approved Ycanth (cantharidin) for treating Molluscum contagiosum, a viral skin infection, was first reporte...
Leveraging computational approaches in identifying novel HER-2 + breast cancer potential therapeutics: integrating virtual screening and molecular dynamics simulation
Leveraging computational approaches in identifying novel HER-2 + breast cancer potential therapeutics: integrating virtual screening and molecular dynamics simulation
Breast cancer, particularly the human epidermal growth factor receptor 2 positive subtype, presents a significant global h...
Augmenting the safety and therapeutic efficacy of doxycycline and rifampicin-loaded solid lipid nanoparticles against Brucella abortus using murine model
Augmenting the safety and therapeutic efficacy of doxycycline and rifampicin-loaded solid lipid nanoparticles against Brucella abortus using murine model
Prolonged therapy, hepatic damage, and the development of drug resistance are the limitations of doxycycline and ...
Repurposing dapagliflozin for Alzheimer's disease: a mechanistic exploration
Repurposing dapagliflozin for Alzheimer's disease: a mechanistic exploration
Several researches describe Alzheimer’s disease (AD) as Type-III diabetes mellitus due to shared pathophysiological ...
Bioactive phytochemicals from leaf extract of Erlangea tomentosa S. Moore (Bothriocline longipes (Oliv. & Hiern.) used to treat bacterial infections in Uganda
Bioactive phytochemicals from leaf extract of Erlangea tomentosa S. Moore (Bothriocline longipes (Oliv. & Hiern.) used to treat bacterial infections in Uganda
The leaves of Erlangea tomentosa (ET) are used to treat several bacterial infections like respiratory tract infections, sk...
Spectrophotometric and HPLC analysis of amoxicillin trihydrate in presence of acetaminophen in different pH media
Spectrophotometric and HPLC analysis of amoxicillin trihydrate in presence of acetaminophen in different pH media
This study is aimed to develop a simple, effective and economic method for the UV spectrophotometric analysis of amoxicill...
Isolation, partial characterization, therapeutic, and safety evaluation of carbapenem-resistant Acinetobacter baumannii lytic phage in a mouse model
Isolation, partial characterization, therapeutic, and safety evaluation of carbapenem-resistant Acinetobacter baumannii lytic phage in a mouse model
Antimicrobial resistance (AMR) is a major worldwide health concern, characterized by the ability of microorganisms to with...
Phytoremediation and ethnomedicinal potential of Buddleja, Eremophila, Scrophularia, and Verbascum genera belonging to the Scrophulariaceae family: a review
Phytoremediation and ethnomedicinal potential of Buddleja, Eremophila, Scrophularia, and Verbascum genera belonging to the Scrophulariaceae family: a review
A number of species have developed detoxification strategies that allow them to accumulate high amounts of heavy metals in...
Development and validation of a UV spectrophotometric method for simultaneous estimation of teneligliptin hydrobromide hydrate and pioglitazone hydrochloride in pharmaceutical dosage form
Development and validation of a UV spectrophotometric method for simultaneous estimation of teneligliptin hydrobromide hydrate and pioglitazone hydrochloride in pharmaceutical dosage form
This study presents the development and validation of a UV spectrophotometric method for the simultaneous estimation of te...
Anti-oxidative, anti-AChE and neuroprotective effect of hydro-alcoholic extract of Sansevieria cylindrica leaves and Plumeria obtusa seed pods in Wistar rats
Anti-oxidative, anti-AChE and neuroprotective effect of hydro-alcoholic extract of Sansevieria cylindrica leaves and Plumeria obtusa seed pods in Wistar rats
The rising incidence of neurodegenerative diseases represents a significant global health concern. The prognosis for such ...
Exploring the potential of curcumin-loaded PLGA nanoparticles for angiogenesis and antioxidant proficiency in zebrafish embryo (Danio rerio)
Exploring the potential of curcumin-loaded PLGA nanoparticles for angiogenesis and antioxidant proficiency in zebrafish embryo (Danio rerio)
Curcumin is an age old traditional medicine. Although curcumin has several advantages, its water solubility and bioavailab...
The evidence-based new vista to wane the utilization of antimicrobials in UTIs
The evidence-based new vista to wane the utilization of antimicrobials in UTIs
In recent years, antibiotic resistance rates have become a global concern for clinicians to combat the pathogenic bacteria...
Efficacy and safety of ziltivekimab in patients with chronic kidney disease susceptible to inflammatory diseases: a systematic review and meta-analysis of randomized controlled trials
Efficacy and safety of ziltivekimab in patients with chronic kidney disease susceptible to inflammatory diseases: a systematic review and meta-analysis of randomized controlled trials
Patients with chronic kidney disease (CKD) are at risk of developing conditions such as atherosclerosis and inflammation-i...
Red, green, and blue model assessment and AQbD approach to HPTLC method for concomitant analysis of metformin, pioglitazone, and teneligliptin
Red, green, and blue model assessment and AQbD approach to HPTLC method for concomitant analysis of metformin, pioglitazone, and teneligliptin
The CDSCO of India has authorized a combination of metformin hydrochloride, teneligliptin hydrochloride, and pioglitazone ...
Different approaches in management of neonatal unconjugated hyperbilirubinemia: a review article
Different approaches in management of neonatal unconjugated hyperbilirubinemia: a review article
Neonatal hyperbilirubinemia is a prevalent condition that affects newborns, characterized by elevated serum bilirubin leve...
Lignin-chitosan-based biocomposite film for the localized delivery of TLR7 agonist imiquimod
Lignin-chitosan-based biocomposite film for the localized delivery of TLR7 agonist imiquimod
As the leading form of non-melanoma skin cancer, basal cell carcinoma (BCC) presents a considerable challenge to healthcar...
Multifunctional approach with LHRH-mediated PLGA nanoconjugate for site-specific codelivery of curcumin and BCL2 siRNA in mice lung cancer
Multifunctional approach with LHRH-mediated PLGA nanoconjugate for site-specific codelivery of curcumin and BCL2 siRNA in mice lung cancer
Lung cancer remains a leading cancer type, but current chemotherapy is limited by issues including poor drug delivery, tox...
Nanocochleate-based delivery of quercetin with enhanced therapeutic potential: formulation, cytotoxicity and pharmacokinetics study
Nanocochleate-based delivery of quercetin with enhanced therapeutic potential: formulation, cytotoxicity and pharmacokinetics study
Quercetin has well-proven anticancer potential through various mechanisms, but its applications in drug delivery are limit...
Computational and experimental insights into glycyrrhizin-loaded nanostructured lipid carriers: docking, dynamics, design optimization, and anticancer efficacy in lung cancer cells
Computational and experimental insights into glycyrrhizin-loaded nanostructured lipid carriers: docking, dynamics, design optimization, and anticancer efficacy in lung cancer cells
Lung cancer (LC) remains a predominant global health concern, especially with escalating tobacco-smoking rates. Present st...
Biogenic synthesis of silver nanoparticles from Hylocereus undatus peel waste: exploring EGFR inhibition for targeted therapy of cervical and breast carcinomas
Biogenic synthesis of silver nanoparticles from Hylocereus undatus peel waste: exploring EGFR inhibition for targeted therapy of cervical and breast carcinomas
Cancer is one of the leading causes of death worldwide, with breast and cervical cancers being the most common among women...
Development, characterization, and assessment of PLAROsomal vesicular system of curcumin for enhanced stability and therapeutic efficacy
Development, characterization, and assessment of PLAROsomal vesicular system of curcumin for enhanced stability and therapeutic efficacy
Curcumin (CUR) is a natural polyphenol and one of the key phytoconstituents found in the rhizomes of Curcuma Longa. It exh...
Novel RP-HPLC method for simultaneous determination of dapagliflozin and teneligliptin in tablet formulation and identification of degradation products by LC-MS/MS
Novel RP-HPLC method for simultaneous determination of dapagliflozin and teneligliptin in tablet formulation and identification of degradation products by LC-MS/MS
Diabetes mellitus affects millions globally, necessitating effective management strategies. Glenmark Pharmaceutical Limite...
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