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A cross-sectional survey of hepatitis B virus screening in patients who received immunosuppressive therapy for rheumatoid arthritis in Japan
A cross-sectional survey of hepatitis B virus screening in patients who received immunosuppressive therapy for rheumatoid arthritis in Japan
Patients with a history of hepatitis B virus (HBV) infection who are receiving immunosuppressive therapy are at risk of HB...
Quillaja saponin mitigates methotrexate-provoked renal injury; insight into Nrf-2/Keap-1 pathway modulation with suppression of oxidative stress and inflammation
Quillaja saponin mitigates methotrexate-provoked renal injury; insight into Nrf-2/Keap-1 pathway modulation with suppression of oxidative stress and inflammation
Methotrexate (MTX) is an antineoplastic/immunosuppressive drug, whose clinical use is impeded owing to its serious adverse...
Vaccination status, incidence of adverse events, and awareness of COVID-19 vaccine among outpatients undergoing chemotherapy
Vaccination status, incidence of adverse events, and awareness of COVID-19 vaccine among outpatients undergoing chemotherapy
Cancer has been identified as a risk factor for severe illness and mortality in coronavirus disease (COVID-19), underscori...
Evaluation of a joint workshop on study design for hospital and community pharmacists: a retrospective cross-sectional survey
Evaluation of a joint workshop on study design for hospital and community pharmacists: a retrospective cross-sectional survey
Although pharmacists often identify numerous clinical questions, they face several barriers, including the lack of mentors...
Renal function and lipid metabolism in Japanese HIV-1-positive individuals 288 weeks after switching from tenofovir disoproxil fumarate to tenofovir alafenamide fumarate: a single-center, retrospective cohort study
Renal function and lipid metabolism in Japanese HIV-1-positive individuals 288 weeks after switching from tenofovir disoproxil fumarate to tenofovir alafenamide fumarate: a single-center, retrospective cohort study
Continued use of tenofovir disoproxil fumarate (TDF), an antiretroviral drug, causes renal function decline and tubular da...
Evaluation after implementation of chemical bowel preparation for surgical site infections in elective colorectal cancer surgery and role of antimicrobial stewardship pharmacist: Retrospective cohort study
Evaluation after implementation of chemical bowel preparation for surgical site infections in elective colorectal cancer surgery and role of antimicrobial stewardship pharmacist: Retrospective cohort study
We evaluated the predictive factors for surgical site infections (SSIs) in elective colorectal cancer surgery and the role...
In-vitro evaluation of Indigofera heterantha extracts for antibacterial, antifungal and anthelmintic activities
In-vitro evaluation of Indigofera heterantha extracts for antibacterial, antifungal and anthelmintic activities
Multidrug-resistant bacterial strains cause several serious infections that can be fatal, such as Enterococcus faecium, St...
Evaluation of hospital pharmacists’ activities using additional reimbursement for infection prevention as an indicator in small and medium-sized hospitals
Evaluation of hospital pharmacists’ activities using additional reimbursement for infection prevention as an indicator in small and medium-sized hospitals
Hospitals in Japan established the healthcare delivery system from FY 2018 to 2021 by acquiring an additional reimbursemen...
Validation of an automated sample preparation module directly connected to LC-MS/MS (CLAM-LC-MS/MS system) and comparison with conventional immunoassays for quantitation of tacrolimus and cyclosporin A in a clinical setting
Validation of an automated sample preparation module directly connected to LC-MS/MS (CLAM-LC-MS/MS system) and comparison with conventional immunoassays for quantitation of tacrolimus and cyclosporin A in a clinical setting
Therapeutic drug monitoring (TDM) systems generally use either liquid chromatography/tandem mass spectrometry (LC-MS/MS) o...
A case with a trend of QT interval prolongation due to the introduction of methadone to a pancreatic cancer patient on levofloxacin
A case with a trend of QT interval prolongation due to the introduction of methadone to a pancreatic cancer patient on levofloxacin
As methadone can prevent the development of opioid resistance, it has application in alleviating cancer-related pain that ...
Temporal trends in antipsychotic prescriptions for pediatric patients using an administrative hospital database in Japan: a retrospective study
Temporal trends in antipsychotic prescriptions for pediatric patients using an administrative hospital database in Japan: a retrospective study
Schizophrenia is a psychiatric disorder characterized by hallucinations, delusions, and other symptoms. Although treatment...
Health-related quality of life and its associated factors among hemophilia patients: experience from Ethiopian Hemophilia Treatment Centre
Health-related quality of life and its associated factors among hemophilia patients: experience from Ethiopian Hemophilia Treatment Centre
Hemophilia is a rare genetic condition that is often overlooked and underdiagnosed, particularly in low-income countries. ...
Five years of safety profile of bevacizumab: an analysis of real-world pharmacovigilance and randomized clinical trials
Five years of safety profile of bevacizumab: an analysis of real-world pharmacovigilance and randomized clinical trials
Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It has a wide range of clinical applicati...
Influence of filtering on the effective concentration and sterility of a 2% cyclosporine ophthalmic solution: a quality improvement perspective
Influence of filtering on the effective concentration and sterility of a 2% cyclosporine ophthalmic solution: a quality improvement perspective
Pharmaceutical companies do not sell formulations for all diseases; thus, healthcare workers have to treat some diseases b...
Impact of HBcrAg levels on HBsAg seroconversion after HBV rebound: a case report
Impact of HBcrAg levels on HBsAg seroconversion after HBV rebound: a case report
Nucleoside analogues (NAs) such as entecavir are required for at least 12 months when patients with resolved hepatit...
Efficacy of the bleeding risk scoring system for optimal prophylactic anticoagulation therapy of venous thromboembolism in trauma patients: a single-center, retrospective, observational cohort study
Efficacy of the bleeding risk scoring system for optimal prophylactic anticoagulation therapy of venous thromboembolism in trauma patients: a single-center, retrospective, observational cohort study
We developed a bleeding risk scoring system (BRSS) using prophylactic anticoagulation therapy to comprehensively assess th...
Analysis of patients’ thoughts and background factors influencing attitudes toward Deprescribing: interviews to obtain hints for highly satisfying and valid prescriptions
Analysis of patients’ thoughts and background factors influencing attitudes toward Deprescribing: interviews to obtain hints for highly satisfying and valid prescriptions
Prescribing with high levels of medical appropriateness and patient satisfaction improves adherence. However, its appropri...
Reduced blood glucose levels by the combination of vadadustat in an elderly patient with chronic kidney disease who was receiving mitiglinide and sitagliptin: a case report
Reduced blood glucose levels by the combination of vadadustat in an elderly patient with chronic kidney disease who was receiving mitiglinide and sitagliptin: a case report
Our case is the first report showing the development of hypoglycemia following the administration of vadadustat in a patie...
Bleeding risk factors and real-world antithrombotic therapies in elderly patients with atrial fibrillation undergoing percutaneous coronary intervention: a retrospective study
Bleeding risk factors and real-world antithrombotic therapies in elderly patients with atrial fibrillation undergoing percutaneous coronary intervention: a retrospective study
Bleeding risk factors in elderly patients with atrial fibrillation undergoing percutaneous coronary intervention (PCI) are...
Upregulation of brain-derived neurotrophic factor by Shiikuwasha (Citrus depressa Hayata)
Upregulation of brain-derived neurotrophic factor by Shiikuwasha (Citrus depressa Hayata)
A reduction in the brain-derived neurotrophic factor (BDNF) level in the brain causes depression, whereas an increase in i...
Relationship between antihypertensive drug use and number of people with high blood pressure in FY 2018: a descriptive epidemiological study based on the National Database of Health Insurance Claims and Specific Health Checkups of Japan open data
Relationship between antihypertensive drug use and number of people with high blood pressure in FY 2018: a descriptive epidemiological study based on the National Database of Health Insurance Claims and Specific Health Checkups of Japan open data
In most countries barring Japan, antihypertensive drug use has been reported using the defined daily doses/1000 inhabitant...
Adherence of denosumab treatment for low bone mineral density in Japanese people living with HIV: a retrospective observational study
Adherence of denosumab treatment for low bone mineral density in Japanese people living with HIV: a retrospective observational study
Long-term care issues, specifically metabolic bone disorders, are a concern for people living with human immunodeficiency ...
Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation
Elevation of tacrolimus concentration after administration of methotrexate for treatment of graft-versus-host disease in pediatric patients received allogeneic hematopoietic stem cell transplantation
Methotrexate (MTX) is used to treat graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transpla...
Induction of CYP3A activity by dexamethasone may not be strong, even at high doses: insights from a case of tacrolimus co-administration
Induction of CYP3A activity by dexamethasone may not be strong, even at high doses: insights from a case of tacrolimus co-administration
Dexamethasone (DEX) induces CYP3A activity in a concentration-dependent manner. However, no study has examined changes in ...
Effect of rapid cefpodoxime disk screening for early detection of third-generation cephalosporin resistance in Escherichia coli and Klebsiella pneumoniae bacteremia
Effect of rapid cefpodoxime disk screening for early detection of third-generation cephalosporin resistance in Escherichia coli and Klebsiella pneumoniae bacteremia
Several methods have been reported for detecting resistance genes or phenotypic testing on the day of positive blood cultu...
Efficacy of combined use of Suvorexant and Ramelteon in preventing postoperative delirium: a retrospective comparative study
Efficacy of combined use of Suvorexant and Ramelteon in preventing postoperative delirium: a retrospective comparative study
Suvorexant and ramelteon have been presented as useful for preventing postoperative delirium. Previous studies reported on...
Recovery from indomethacin-induced gastrointestinal bleeding by treatment with teprenone
Recovery from indomethacin-induced gastrointestinal bleeding by treatment with teprenone
Gastrointestinal injuries caused by nonsteroidal anti-inflammatory drugs (NSAIDs) is a serious side effect in patients wit...
Heart failure drug classes and 30-day unplanned hospital readmission among patients with heart failure in Ethiopia
Heart failure drug classes and 30-day unplanned hospital readmission among patients with heart failure in Ethiopia
Drug therapy is a crucial aspect of heart failure management and has been shown to reduce morbidity and mortality in heart...
Trends in teicoplanin loading dose implementation from 2010 to 2019 and evaluation of safety and efficacy factors: a retrospective cohort study based on a Japanese administrative claims database
Trends in teicoplanin loading dose implementation from 2010 to 2019 and evaluation of safety and efficacy factors: a retrospective cohort study based on a Japanese administrative claims database
The loading dose of teicoplanin (TEIC) is recommended for implementation. However, there is significant discrepancy betwee...
Faculty publication trends in a Japanese national university: a diachronic document analysis
Faculty publication trends in a Japanese national university: a diachronic document analysis
We previously demonstrated that in a Japanese national university’s medical faculty, overall paper publication frequ...
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