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Unsupervised Clustering in Neurocritical Care: A Systematic Review
Unsupervised Clustering in Neurocritical Care: A Systematic Review
Managing patients with acute brain injury in the neurocritical care (NCC) unit has become increasingly complex because of ...
Long-Term Outcomes After Severe Acute Brain Injury Requiring Mechanical Ventilation: Recovery Trajectories Among Patients and Mental Health Symptoms of Their Surrogate Decision Makers
Long-Term Outcomes After Severe Acute Brain Injury Requiring Mechanical Ventilation: Recovery Trajectories Among Patients and Mental Health Symptoms of Their Surrogate Decision Makers
Long-term outcomes of patients with severe acute brain injury (SABI) and their surrogate decision makers (SDMs) are insuff...
A Propensity Score–Weighted Analysis of Short-Term Corticosteroid Therapy for Refractory Pain Following Spontaneous Subarachnoid Hemorrhage
A Propensity Score–Weighted Analysis of Short-Term Corticosteroid Therapy for Refractory Pain Following Spontaneous Subarachnoid Hemorrhage
Corticosteroids are prescribed for refractory headache in patients with spontaneous subarachnoid hemorrhage (SAH) despite ...
Neuroimaging Markers of Brain Reserve and Associations with Delirium in Patients with Intracerebral Hemorrhage
Neuroimaging Markers of Brain Reserve and Associations with Delirium in Patients with Intracerebral Hemorrhage
Delirium occurs frequently in patients with stroke, but the role of preexisting neural substrates in delirium pathogenesis...
War and Neurologic Trauma
War and Neurologic Trauma
Masson published Guillain and Barré’s 486-page volume Travaux de Neurologigue de Guerre in 1920 (Fig. 1), and they noted t...
Anticoagulation in Acute Stroke: Early Claims and Later Doubts
Anticoagulation in Acute Stroke: Early Claims and Later Doubts
As early as 1943, Allen and Barker suggested that anticoagulants might be of value in the treatment of thrombosis of the c...
Beyond the Pupil: On Cranial Nerves, Brainstem Reflexes, and its Implications
Beyond the Pupil: On Cranial Nerves, Brainstem Reflexes, and its Implications
The discovery of neurophysiology often comes after understanding neuroanatomy. The discovery of the cranial nerves and its...
Extracerebral Normalization of 18F-FDG PET Imaging Combined with Behavioral CRS-R Scores Predict Recovery from Disorders of Consciousness
Extracerebral Normalization of 18F-FDG PET Imaging Combined with Behavioral CRS-R Scores Predict Recovery from Disorders of Consciousness
Identifying patients likely to regain consciousness early on is a challenge. The assessment of consciousness levels and th...
Corticosteroids in Acute Neurology and Neurosurgery: Promises, Promises, Promises
Corticosteroids in Acute Neurology and Neurosurgery: Promises, Promises, Promises
In 1945, Prados et al. [12] noted that when the brain was exposed to air, the blood–brain barrier failed and brain edema d...
The Predictive Validity of the Full Outline of UnResponsiveness Score Compared to the Glasgow Coma Scale in the Intensive Care Unit: A Systematic Review
The Predictive Validity of the Full Outline of UnResponsiveness Score Compared to the Glasgow Coma Scale in the Intensive Care Unit: A Systematic Review
The Full Outline of UnResponsiveness (FOUR) score was developed to overcome the limitations of the Glasgow Coma Scale (GCS...
Uremia and the Brain: The Contentious History of a Small Molecule
Uremia and the Brain: The Contentious History of a Small Molecule
The German pathologist Friedrich Theodor von Frerichs published a monograph in 1851 which focused more on the Uramische In...
Hemorrhage in the Pons: Overlooked No More
Hemorrhage in the Pons: Overlooked No More
In 1856, Gubler called attention to the diagnostic importance of the so called alternate hemiplegia, which has been recogn...
The Delay of Clipping of a Ruptured Cerebral Aneurysm: Unnecessary and Harmful
The Delay of Clipping of a Ruptured Cerebral Aneurysm: Unnecessary and Harmful
The study was a prospective observational epidemiologic study. A randomized controlled trial was considered, but the assum...
Augmented Renal Clearance: Prevalence, Risk Factors and Underlying Mechanism in Critically Ill Patients with Subarachnoid Hemorrhage
Augmented Renal Clearance: Prevalence, Risk Factors and Underlying Mechanism in Critically Ill Patients with Subarachnoid Hemorrhage
Augmented renal clearance (ARC) is an increase in the measured creatinine clearance (CLCR), the cause of which remains poo...
Caring for Coma after Severe Brain Injury: Clinical Practices and Challenges to Improve Outcomes: An Initiative by the Curing Coma Campaign
Caring for Coma after Severe Brain Injury: Clinical Practices and Challenges to Improve Outcomes: An Initiative by the Curing Coma Campaign
Severe brain injury can result in disorders of consciousness (DoC), including coma, vegetative state/unresponsive wakefuln...
Critical Illness Polyneuropathy: Eluding Intensivists Since Its Discovery
Critical Illness Polyneuropathy: Eluding Intensivists Since Its Discovery
The first published observations of this clinical entity had to wait until the early 1980s, after which medical and surgic...
Ethically Translating Advanced Neurotechnologies for Disorders of Consciousness: A Survey of Clinicians’ Perspectives
Ethically Translating Advanced Neurotechnologies for Disorders of Consciousness: A Survey of Clinicians’ Perspectives
Although evaluation of disorders of consciousness (DoC) following brain injury has traditionally relied on bedside behavio...
Acute Traumatic Coma Awakening Induced by Median Nerve Electrical Stimulation: A Systematic Review and Meta-Analysis
Acute Traumatic Coma Awakening Induced by Median Nerve Electrical Stimulation: A Systematic Review and Meta-Analysis
Traumatic brain injury (TBI) is widely recognized as a major cause of death and disability. Optimizing recovery from coma ...
Iodine-Based Dual-Energy Computed Tomography After Mechanical Thrombectomy Predicts Secondary Neurologic Decline from Cerebral Edema After Severe Stroke
Iodine-Based Dual-Energy Computed Tomography After Mechanical Thrombectomy Predicts Secondary Neurologic Decline from Cerebral Edema After Severe Stroke
Patients with severe stroke are at high risk of secondary neurologic decline (ND) from the development of malignant cerebr...
Continuous Blood Pressure Indices During the First 72 Hours and Functional Outcome in Patients with Spontaneous Intracerebral Hemorrhage
Continuous Blood Pressure Indices During the First 72 Hours and Functional Outcome in Patients with Spontaneous Intracerebral Hemorrhage
Management of intracerebral hemorrhage (ICH) is challenged by limited therapeutic options and a complex relationship betwe...
Heart Rate Variability and Cerebral Autoregulation in Patients with Traumatic Brain Injury with Paroxysmal Sympathetic Hyperactivity Syndrome
Heart Rate Variability and Cerebral Autoregulation in Patients with Traumatic Brain Injury with Paroxysmal Sympathetic Hyperactivity Syndrome
Severe traumatic brain injury (TBI) can lead to transient changes in autonomic nervous system (ANS) functioning and develo...
Cisternal Blood Clearance Attenuates Systemic Inflammatory Response After Subarachnoid Hemorrhage
Cisternal Blood Clearance Attenuates Systemic Inflammatory Response After Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (SAH) frequently triggers systemic inflammatory response syndrome (SIRS). SIRS has been...
Elevated Blood Pressure and Culprit Aneurysm Rebleeding During the Unsecured Period of Aneurysmal Subarachnoid Hemorrhage: A Systematic Review
Elevated Blood Pressure and Culprit Aneurysm Rebleeding During the Unsecured Period of Aneurysmal Subarachnoid Hemorrhage: A Systematic Review
In aneurysmal subarachnoid hemorrhage, rebleeding prior to securing the culprit aneurysm leads to significant morbidity an...
Delayed Withdrawal of Life-Sustaining Treatment in Disorders of Consciousness: Practical and Theoretical Considerations
Delayed Withdrawal of Life-Sustaining Treatment in Disorders of Consciousness: Practical and Theoretical Considerations
Disorders of consciousness (DoC) resulting from severe acute brain injuries may prompt clinicians and surrogate decision m...
Liberalization of the Systemic Glucose Management is Associated with a Reduced Frequency of Neuroglucopenia in Subarachnoid Hemorrhage Patients: An Observational Cohort Study
Liberalization of the Systemic Glucose Management is Associated with a Reduced Frequency of Neuroglucopenia in Subarachnoid Hemorrhage Patients: An Observational Cohort Study
Pathologically low brain glucose levels, referred to as neuroglucopenia, are associated with unfavorable outcomes in neuro...
Efficacy and Safety of Andexanet Alfa Versus Four Factor Prothrombin Complex Concentrate for Emergent Reversal of Factor Xa Inhibitor Associated Intracranial Hemorrhage: A Systematic Review and Meta-Analysis
Efficacy and Safety of Andexanet Alfa Versus Four Factor Prothrombin Complex Concentrate for Emergent Reversal of Factor Xa Inhibitor Associated Intracranial Hemorrhage: A Systematic Review and Meta-Analysis
Factor Xa inhibitors (FXaI) are increasingly used for anticoagulation therapy, yet their association with intracranial hem...
Which Intravenous Isotonic Fluid Offers Better Outcomes for Patients with a Brain Injury?
Which Intravenous Isotonic Fluid Offers Better Outcomes for Patients with a Brain Injury?
Administering intravenous fluids is a common therapy for critically ill patients. Isotonic crystalloid solutions, such as ...
Contribution of an Automatic Algorithm for Quantifying the Volume of Aneurysmal Subarachnoid Hemorrhage to the Evaluation of the Risk of Occurrence of Delayed Cerebral Ischemia: A Cohort Study
Contribution of an Automatic Algorithm for Quantifying the Volume of Aneurysmal Subarachnoid Hemorrhage to the Evaluation of the Risk of Occurrence of Delayed Cerebral Ischemia: A Cohort Study
This study focuses on aneurysmal subarachnoid hemorrhage (aSAH) with a high risk of delayed cerebral ischemia (DCI) and ac...
Comparative Efficacy and Safety of External Ventricular Drains and Intraparenchymal Pressure Monitors for Intracranial Pressure Monitoring in Traumatic Brain Injury: A Systematic Review and Meta-analysis
Comparative Efficacy and Safety of External Ventricular Drains and Intraparenchymal Pressure Monitors for Intracranial Pressure Monitoring in Traumatic Brain Injury: A Systematic Review and Meta-analysis
In the management of traumatic brain injury (TBI), intracranial pressure monitoring (ICPm) is crucial for the timely manag...
Feasibility Study of Endoscopic Surgery for Spontaneous Intracerebral Hemorrhage with Large Hematoma: a Comparison with Craniotomy Using Propensity Score Matching Analysis
Feasibility Study of Endoscopic Surgery for Spontaneous Intracerebral Hemorrhage with Large Hematoma: a Comparison with Craniotomy Using Propensity Score Matching Analysis
Spontaneous intracerebral hemorrhage (ICH) with large hematomas is commonly treated with craniotomy combined with decompre...
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