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SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53
SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53
Bladder cancer (BCa) is one of the most common malignancies worldwide. However, the lack of accurate and effective targete...
Targeting MYH9 represses USP14-mediated NAP1L1 deubiquitination and cell proliferation in glioma
Targeting MYH9 represses USP14-mediated NAP1L1 deubiquitination and cell proliferation in glioma
Myosin heavy chain 9 (MYH9) plays an important role in a number of diseases. Nevertheless, the function of MYH9 in glioma ...
FAP promotes clear cell renal cell carcinoma progression via activating the PI3K/AKT/mTOR signaling pathway
FAP promotes clear cell renal cell carcinoma progression via activating the PI3K/AKT/mTOR signaling pathway
Herein, we aimed at exploring the FAP expression in clear cell renal cell carcinoma (ccRCC) along with its clinical implic...
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress
Lung cancer is a leading cause of cancer-related deaths, and the most common type is lung adenocarcinoma (LUAD). LUAD is f...
Prognosis of Midkine and AT1R expression in resectable head and neck squamous cell carcinoma
Prognosis of Midkine and AT1R expression in resectable head and neck squamous cell carcinoma
Research studies have demonstrated that Midkine (MDK) can influence the expression and activity of Renin-angiotensin syste...
The pyrazole derivative of usnic acid inhibits the proliferation of pancreatic cancer cells in vitro and in vivo
The pyrazole derivative of usnic acid inhibits the proliferation of pancreatic cancer cells in vitro and in vivo
Pancreatic cancer is one of the leading causes of cancer death in Western societies. Its late diagnosis and resistance to ...
Synergistic effects of flavonoids and paclitaxel in cancer treatment: a systematic review
Synergistic effects of flavonoids and paclitaxel in cancer treatment: a systematic review
Paclitaxel is a natural anticancer compound with minimal toxicity, the capacity to stabilize microtubules, and high effici...
Synergistic effect of YOD1 and USP21 on the Hippo signaling pathway
Synergistic effect of YOD1 and USP21 on the Hippo signaling pathway
Deubiquitinating enzymes (DUBs) comprise a family of proteases responsible for cleaving the peptide or isopeptide bond bet...
The novel oncogenic factor TET3 combines with AHR to promote thyroid cancer lymphangiogenesis via the HIF-1α/VEGF signaling pathway
The novel oncogenic factor TET3 combines with AHR to promote thyroid cancer lymphangiogenesis via the HIF-1α/VEGF signaling pathway
Lymphangiogenesis has been reported to play crucial roles in the metastasis of thyroid cancer (THCA), but despite the sign...
Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia
Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia
Outcomes for patients with relapsed acute lymphoblastic leukemia (ALL) are poor and there is a need for novel therapies to...
ARF6 promotes hepatocellular carcinoma proliferation through activating STAT3 signaling
ARF6 promotes hepatocellular carcinoma proliferation through activating STAT3 signaling
Hepatocellular Carcinoma (HCC) possesses the high mortality in cancers worldwide. Nevertheless, the concrete mechanism und...
Enhancing HCC Treatment: innovatively combining HDAC2 inhibitor with PD-1/PD-L1 inhibition
Enhancing HCC Treatment: innovatively combining HDAC2 inhibitor with PD-1/PD-L1 inhibition
Hepatocellular carcinoma (HCC) is a malignancy with high morbidity and mortality but lacks effective treatments thus far. ...
Stimulators of immunogenic cell death for cancer therapy: focusing on natural compounds
Stimulators of immunogenic cell death for cancer therapy: focusing on natural compounds
A growing body of evidence indicates that the anticancer effect of the immune system can be activated by the immunogenic m...
LncRNA SNHG1: role in tumorigenesis of multiple human cancers
LncRNA SNHG1: role in tumorigenesis of multiple human cancers
Small nucleolar RNA host gene 1 (SNHG1) is an important member of the SNHG family. This family is composed of a group of h...
Identification and validation of a novel prognosis model based on m5C-related long non-coding RNAs in colorectal cancer
Identification and validation of a novel prognosis model based on m5C-related long non-coding RNAs in colorectal cancer
The prognosis of tumor patients can be assessed by measuring the levels of lncRNAs (long non-coding RNAs), which play a ro...
PTBP1 plays an important role in the development of gastric cancer
PTBP1 plays an important role in the development of gastric cancer
Polypyrimidine tract binding protein 1 (PTBP1) has been found to play an important role in the occurrence and development ...
LncRNA CYP4A22-AS1 promotes the progression of lung adenocarcinoma through the miR-205-5p/EREG and miR-34c-5p/BCL-2 axes
LncRNA CYP4A22-AS1 promotes the progression of lung adenocarcinoma through the miR-205-5p/EREG and miR-34c-5p/BCL-2 axes
Lung adenocarcinoma (LUAD) exhibits a higher fatality rate among all cancer types worldwide, yet the precise mechanisms un...