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YY1 promotes pancreatic cancer cell proliferation by enhancing mitochondrial respiration
YY1 promotes pancreatic cancer cell proliferation by enhancing mitochondrial respiration
KRAS-driven metabolic reprogramming is a known peculiarity features of pancreatic ductal adenocarcinoma (PDAC) cells. Howe...
ROR2, a driver of “phenotype switching” in melanoma?
ROR2, a driver of “phenotype switching” in melanoma?
Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a receptor for the Wnt5a ligand that was shown to play a dual ro...
A review on the role of MEG8 lncRNA in human disorders
A review on the role of MEG8 lncRNA in human disorders
Maternally expressed 8 (MEG8) is a long non-coding RNA which is expressed in the nucleus. It is highly expressed in adrena...
Emerging role of non-coding RNAs in the regulation of Sonic Hedgehog signaling pathway
Emerging role of non-coding RNAs in the regulation of Sonic Hedgehog signaling pathway
Sonic Hedgehog (Shh) signaling cascade is one of the complex signaling pathways that control the accurately organized deve...
miR-1908: a microRNA with diverse functions in cancers and non-malignant conditions
miR-1908: a microRNA with diverse functions in cancers and non-malignant conditions
MicroRNAs (miRNAs) are small-sized transcripts with about 22 nucleotide length. They have been shown to influence almost e...
TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma
TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and has an extremely poor prognosis. We aim...
Prostate cancer in omics era
Prostate cancer in omics era
Recent advances in omics technology have prompted extraordinary attempts to define the molecular changes underlying the on...
Combination treatment with hENT1 and miR-143 reverses gemcitabine resistance in triple-negative breast cancer
Combination treatment with hENT1 and miR-143 reverses gemcitabine resistance in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer and is susceptible to develop gemcitabine (...
A review on the role of LINC01133 in cancers
A review on the role of LINC01133 in cancers
Long Intergenic Non-Protein Coding RNA 1133 (LINC01133) is a long non-coding RNA (lncRNA) which interacts with miR-106a-3p...
Antitumor immunity and therapeutic properties of marine seaweeds-derived extracts in the treatment of cancer
Antitumor immunity and therapeutic properties of marine seaweeds-derived extracts in the treatment of cancer
Marine seaweeds are important sources of drugs with several pharmacological characteristics. The present study aims to eva...
ITGAL infers adverse prognosis and correlates with immunity in acute myeloid leukemia
ITGAL infers adverse prognosis and correlates with immunity in acute myeloid leukemia
Integrin subunit alpha L (ITGAL) was found aberrantly expressed in multiple cancer types, suggesting its essential role in...
The role of ferroptosis in esophageal cancer
The role of ferroptosis in esophageal cancer
Esophageal cancer is one of the most common cancers with high mortality rate around the world. Although the treatment stra...
Multimodal targeting of glioma with functionalized nanoparticles
Multimodal targeting of glioma with functionalized nanoparticles
The most common and aggressive primitive intracranial tumor of the central nervous system is the glioma. The blood–b...
A novel quantitative prognostic model for initially diagnosed non-small cell lung cancer with brain metastases
A novel quantitative prognostic model for initially diagnosed non-small cell lung cancer with brain metastases
The prognosis of non-small cell lung cancer (NSCLC) with brain metastases (BMs) had been researched in some researches, bu...
Correction: Genistein as a regulator of signaling pathways and microRNAs in different types of cancers
Correction: Genistein as a regulator of signaling pathways and microRNAs in different types of cancers
Office of Research Innovation and Commercialization (ORIC), Lahore Garrison University, Sector-C, DHA Phase-VI, Lahore, Pa...
Role of PI3K/AKT pathway in squamous cell carcinoma with an especial focus on head and neck cancers
Role of PI3K/AKT pathway in squamous cell carcinoma with an especial focus on head and neck cancers
PI3K/AKT pathway is an important pathway in the carcinogenesis since it has central impacts in the regulation of metabolic...
Potential of antibody–drug conjugates (ADCs) for cancer therapy
Potential of antibody–drug conjugates (ADCs) for cancer therapy
The primary purpose of ADCs is to increase the efficacy of anticancer medications by minimizing systemic drug distribution...
Noncoding RNA-mediated molecular bases of chemotherapy resistance in hepatocellular carcinoma
Noncoding RNA-mediated molecular bases of chemotherapy resistance in hepatocellular carcinoma
Despite the significant progress in decreasing the occurrence and mortality of hepatocellular carcinoma (HCC), it remains ...
Exercise and colorectal cancer: prevention and molecular mechanisms
Exercise and colorectal cancer: prevention and molecular mechanisms
Exercise and physical activity have been shown to be strongly associated with a decreased incidence rate of various chroni...
Targeting Ras-ERK cascade by bioactive natural products for potential treatment of cancer: an updated overview
Targeting Ras-ERK cascade by bioactive natural products for potential treatment of cancer: an updated overview
MAPK (mitogen-activated protein kinase) or ERK (extracellular-signal-regulated kinase) pathway is an important link in the...