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Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA199
Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA199
Immunotherapy and radiotherapy play crucial roles in the transformation therapy of locally advanced pancreatic cancer; how...
Senescence-related circRNA circHIF-1α is associated with pancreatic cancer progression
Senescence-related circRNA circHIF-1α is associated with pancreatic cancer progression
Recently, there has been growing interest in the role of circular RNAs (circRNAs) in the progression of human cancers. Cel...
Evaluation of plasma cell sorting methods in multiple myeloma patients: flow cytometry versus magnetic beads
Evaluation of plasma cell sorting methods in multiple myeloma patients: flow cytometry versus magnetic beads
The prognosis of a plasma cell neoplasm (PCN) varies depending on the presence of genetic abnormalities. However, detectin...
The expression landscape and clinical significance of methyltransferase-like 17 in human cancer and hepatocellular carcinoma: a pan-cancer analysis using multiple databases
The expression landscape and clinical significance of methyltransferase-like 17 in human cancer and hepatocellular carcinoma: a pan-cancer analysis using multiple databases
Methyltransferase-like (METTL) family protein plays a crucial role in the progression of malignancies. However, the functi...
Construction of the bromodomain-containing protein-associated prognostic model in triple-negative breast cancer
Construction of the bromodomain-containing protein-associated prognostic model in triple-negative breast cancer
Bromodomain-containing protein (BRD) play a pivotal role in the development and progression of malignant tumours. This stu...
Predictive value of dendritic cell-related genes for prognosis and immunotherapy response in lung adenocarcinoma
Predictive value of dendritic cell-related genes for prognosis and immunotherapy response in lung adenocarcinoma
Patients with lung adenocarcinoma (LUAD) receiving drug treatment often have an unpredictive response and there is a lack ...
Association of whole grain food consumption with lung cancer risk: a prospective cohort study
Association of whole grain food consumption with lung cancer risk: a prospective cohort study
Whether the intake of whole grain foods can protect against lung cancer is a long-standing question of considerable public...
Establishment and characterization of a new mouse gastric carcinoma cell line, MCC
Establishment and characterization of a new mouse gastric carcinoma cell line, MCC
The aim of this study was to establish a primary mouse gastric carcinoma cell line. Gastric adenocarcinoma in the body reg...
Characterizing tertiary lymphoid structures associated single-cell atlas in breast cancer patients
Characterizing tertiary lymphoid structures associated single-cell atlas in breast cancer patients
The tertiary lymphoid structure (TLS) is recognized as a potential prognosis factor for breast cancer and is strongly asso...
Heterogeneous nuclear ribonucleoprotein C promotes non-small cell lung cancer progression by enhancing XB130 mRNA stability and translation
Heterogeneous nuclear ribonucleoprotein C promotes non-small cell lung cancer progression by enhancing XB130 mRNA stability and translation
XB130, a classical adaptor protein, exerts a critical role in diverse cellular processes. Aberrant expression of XB130 is ...
Deapioplatycodin D inhibits glioblastoma cell proliferation by inducing BNIP3L-mediated incomplete mitophagy
Deapioplatycodin D inhibits glioblastoma cell proliferation by inducing BNIP3L-mediated incomplete mitophagy
Deapioplatycodin D (DPD) is a triterpenoid saponin natural compound isolated from the Chinese herb Platycodon grandiflorum...
CASP5 associated with PANoptosis promotes tumorigenesis and progression of clear cell renal cell carcinoma
CASP5 associated with PANoptosis promotes tumorigenesis and progression of clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is a globally severe cancer with an unfavorable prognosis. PANoptosis, a form of c...
Super-enhancers in hepatocellular carcinoma: regulatory mechanism and therapeutic targets
Super-enhancers in hepatocellular carcinoma: regulatory mechanism and therapeutic targets
Super-enhancers (SEs) represent a distinct category of cis-regulatory elements notable for their robust transcriptional ac...
The interplay of exercise and green tea: a new road in cancer therapy
The interplay of exercise and green tea: a new road in cancer therapy
Exercise is one of the most important activities for every individual due to its proven health beneficials. Several invest...
A1, an innovative fluorinated CXCR4 inhibitor, redefines the therapeutic landscape in colorectal cancer
A1, an innovative fluorinated CXCR4 inhibitor, redefines the therapeutic landscape in colorectal cancer
Colorectal cancer (CRC) is a globally prevalent malignancy, primarily affecting the colon and rectum, characterized by unc...
Predicting hepatocellular carcinoma outcomes and immune therapy response with ATP-dependent chromatin remodeling-related genes, highlighting MORF4L1 as a promising target
Predicting hepatocellular carcinoma outcomes and immune therapy response with ATP-dependent chromatin remodeling-related genes, highlighting MORF4L1 as a promising target
Hepatocellular carcinoma (HCC) continues to be a major cause of cancer-related death worldwide, primarily due to delays in...
Interaction of AURKA with TRIM28 revives dormant LSCC cells via Akt signaling pathway to promote LSCC metastasis
Interaction of AURKA with TRIM28 revives dormant LSCC cells via Akt signaling pathway to promote LSCC metastasis
Specific molecular mechanisms by which AURKA promoted LSCC metastasis were still unknown. Bioinformatic analysis was perfo...
Potential role of P4HB in the tumor microenvironment and its clinical prognostic value: a comprehensive pan-cancer analysis and experimental validation with a focus on KIRC
Potential role of P4HB in the tumor microenvironment and its clinical prognostic value: a comprehensive pan-cancer analysis and experimental validation with a focus on KIRC
Tumor microenvironment (TME) plays a crucial role in tumor growth and metastasis. Exploring biomarkers that are significan...
Current status and innovative developments of CAR-T-cell therapy for the treatment of breast cancer
Current status and innovative developments of CAR-T-cell therapy for the treatment of breast cancer
Breast cancer will overtake all other cancers in terms of diagnoses in 2024. Breast cancer counts highest among women in t...
Novel research model for in vitro immunotherapy: co-culturing tumor organoids with peripheral blood mononuclear cells
Novel research model for in vitro immunotherapy: co-culturing tumor organoids with peripheral blood mononuclear cells
Tumor organoids have emerged as powerful tools for in vitro cancer research due to their ability to retain the structural ...
Novel insights into the interaction between IGF2BPs and ncRNAs in cancers
Novel insights into the interaction between IGF2BPs and ncRNAs in cancers
Insulin-like growth factor II mRNA-binding proteins (IGF2BPs), a family of RNA-binding proteins, are pivotal in regulating...
Prognostic value and immune infiltration of a tumor microenvironment-related PTPN6 in metastatic melanoma
Prognostic value and immune infiltration of a tumor microenvironment-related PTPN6 in metastatic melanoma
Cutaneous melanoma is one of the most invasive and lethal skin malignant tumors. Compared to primary melanoma, metastatic ...
Correction: Long non-coding RNA CCL14-AS suppresses invasiveness and lymph node metastasis of colorectal cancer cells by regulating MEP1A
Correction: Long non-coding RNA CCL14-AS suppresses invasiveness and lymph node metastasis of colorectal cancer cells by regulating MEP1A
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Ultrasound-responsive nanoparticles for nitric oxide release to inhibit the growth of breast cancer
Ultrasound-responsive nanoparticles for nitric oxide release to inhibit the growth of breast cancer
Gas therapy represents a promising strategy for cancer treatment, with nitric oxide (NO) therapy showing particular potent...
Protein kinase CK2 sustains de novo fatty acid synthesis by regulating the expression of SCD-1 in human renal cancer cells
Protein kinase CK2 sustains de novo fatty acid synthesis by regulating the expression of SCD-1 in human renal cancer cells
Clear cell renal cell carcinoma (ccRCC) is a type of cancer characterized by a vast intracellular accumulation of lipids t...
Competing endogenous RNAs network dysregulation in oral cancer: a multifaceted perspective on crosstalk and competition
Competing endogenous RNAs network dysregulation in oral cancer: a multifaceted perspective on crosstalk and competition
Oral cancer progresses from asymptomatic to advanced stages, often involving cervical lymph node metastasis, resistance to...
GANT61 surmounts drug resistance of ADR by upregulating lysosome activities and reducing BCL2 expression in HL-60/ADR cells
GANT61 surmounts drug resistance of ADR by upregulating lysosome activities and reducing BCL2 expression in HL-60/ADR cells
Drug resistance remains a significant obstacle to Acute myeloid leukemia (AML) successful treatment, often leading to ther...
Organoids as a model system for researching human neuroendocrine tumor of the breast
Organoids as a model system for researching human neuroendocrine tumor of the breast
Neuroendocrine tumors primarily consist of endocrine cells commonly located in neural tissue and the endocrine system. Pri...
Aldo-keto reductase family 1 member B10 prevents esophageal squamous cell carcinoma from reactive carbonyl species-induced cell death and promotes its progression
Aldo-keto reductase family 1 member B10 prevents esophageal squamous cell carcinoma from reactive carbonyl species-induced cell death and promotes its progression
Chronic alcohol consumption and tobacco usage are major risk factors for esophageal squamous cell carcinoma (ESCC). Excess...
The expression of pro-prion, a transmembrane isoform of the prion protein, leads to the constitutive activation of the canonical Wnt/β-catenin pathway to sustain the stem-like phenotype of human glioblastoma cells
The expression of pro-prion, a transmembrane isoform of the prion protein, leads to the constitutive activation of the canonical Wnt/β-catenin pathway to sustain the stem-like phenotype of human glioblastoma cells
Cellular prion protein (PrPC) is a widely expressed membrane-anchored glycoprotein, which has been associated wit...
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