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A risk model developed based on necroptosis to assess progression for ischemic cardiomyopathy and identify possible therapeutic drugs
A risk model developed based on necroptosis to assess progression for ischemic cardiomyopathy and identify possible therapeutic drugs
Object: Ischemic cardiomyopathy (ICM), with high morbidity and mortality, is the most common cause of heart failure. Cardi...
Community pharmacists’ views and experiences toward over-the-counter medicines misuse and abuse in Saudi Arabia: A qualitative study
Community pharmacists’ views and experiences toward over-the-counter medicines misuse and abuse in Saudi Arabia: A qualitative study
Background: Community pharmacists are uniquely positioned to identify and address the issue of misuse and abuse of over-th...
Analysis of the safety and efficacy of different plasma concentrations of pirfenidone in patients with idiopathic pulmonary fibrosis
Analysis of the safety and efficacy of different plasma concentrations of pirfenidone in patients with idiopathic pulmonary fibrosis
The high incidence and mortality of idiopathic pulmonary fibrosis (IPF) have led to the widespread use of antifibrotic dru...
Antiviral effects of the petroleum ether extract of Tournefortia sibirica L. against enterovirus 71 infection in vitro and in vivo
Antiviral effects of the petroleum ether extract of Tournefortia sibirica L. against enterovirus 71 infection in vitro and in vivo
Enterovirus 71 (EV71) is the major cause of severe hand, foot, and mouth disease (HFMD). Compared to other HFMD pathogens,...
Inhaled platelet vesicle-decoyed biomimetic nanoparticles attenuate inflammatory lung injury
Inhaled platelet vesicle-decoyed biomimetic nanoparticles attenuate inflammatory lung injury
Acute lung injury (ALI) is an inflammatory response which causes serious damages to alveolar epithelia and vasculature, an...
Feiyanning formula modulates the molecular mechanism of osimertinib resistance in lung cancer by regulating the Wnt/β-catenin pathway
Feiyanning formula modulates the molecular mechanism of osimertinib resistance in lung cancer by regulating the Wnt/β-catenin pathway
Feiyanning Formula (FYN), a Chinese herbal formula derived from summarized clinical experience, is proven to have anti-tum...
LncRNA MEG3: Potential stock for precision treatment of cardiovascular diseases
LncRNA MEG3: Potential stock for precision treatment of cardiovascular diseases
The prevalence and mortality rates of cardiovascular diseases are increasing, and new treatment strategies are urgently ne...
Primary cilia: The central role in the electromagnetic field induced bone healing
Primary cilia: The central role in the electromagnetic field induced bone healing
Primary cilia have emerged as the cellular “antenna” that can receive and transduce extracellular chemical/physical signal...
Drug-induced fall risk in older patients: A pharmacovigilance study of FDA adverse event reporting system database
Drug-induced fall risk in older patients: A pharmacovigilance study of FDA adverse event reporting system database
Objectives: As fall events and injuries have become a growing public health problem in older patients and the causes of fa...
Noble gas and neuroprotection: From bench to beside
Noble gas and neuroprotection: From bench to beside
In recent years, inert gases such as helium, argon, and xenon have gained considerable attention for their medical value. ...
Targeting the chemerin/CMKLR1 axis by small molecule antagonist α-NETA mitigates endometriosis progression
Targeting the chemerin/CMKLR1 axis by small molecule antagonist α-NETA mitigates endometriosis progression
Endometriosis is a common gynecological disease, characterized by the presence of endometrial-like lesions outside the ute...
Adolescent kratom exposure affects cognitive behaviours and brain metabolite profiles in Sprague-Dawley rats
Adolescent kratom exposure affects cognitive behaviours and brain metabolite profiles in Sprague-Dawley rats
Adolescence is a critical developmental period during which exposure to psychoactive substances like kratom (Mitragyna spe...
Aqueous extract of Artemisia capillaris improves non-alcoholic fatty liver and obesity in mice induced by high-fat diet
Aqueous extract of Artemisia capillaris improves non-alcoholic fatty liver and obesity in mice induced by high-fat diet
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases and is a nutritional metabolic ...
Cinobufagin alleviates lipopolysaccharide-induced acute lung injury by regulating autophagy through activation of the p53/mTOR pathway
Cinobufagin alleviates lipopolysaccharide-induced acute lung injury by regulating autophagy through activation of the p53/mTOR pathway
Acute lung injury (ALI) is a severe clinical disorder characterized by dysregulated inflammatory responses, leading to hig...
Ethnomedicinal, phytochemical and pharmacological investigations of Baccharis dracunculifolia DC. (ASTERACEAE)
Ethnomedicinal, phytochemical and pharmacological investigations of Baccharis dracunculifolia DC. (ASTERACEAE)
Baccharis dracunculifolia DC (Lamiaceae) (Asteraceae) is found in South America, mainly in Argentina, Brazil, Bolivia, Par...
SLC2As as diagnostic markers and therapeutic targets in LUAD patients through bioinformatic analysis
SLC2As as diagnostic markers and therapeutic targets in LUAD patients through bioinformatic analysis
Facilitative glucose transporters (GLUTs), which are encoded by solute carrier 2A (SLC2A) genes, are responsible for media...
New developments and opportunities in drugs being trialed for amyotrophic lateral sclerosis from 2020 to 2022
New developments and opportunities in drugs being trialed for amyotrophic lateral sclerosis from 2020 to 2022
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that primarily affects motor neurons in th...
Drug-induced liver injury in COVID-19 treatment: Incidence, mechanisms and clinical management
Drug-induced liver injury in COVID-19 treatment: Incidence, mechanisms and clinical management
The COVID-19 outbreak triggered a serious and potentially lethal pandemic, resulting in massive health and economic losses...
Immunotherapy and targeted therapy for lung cancer: Current status and future perspectives
Immunotherapy and targeted therapy for lung cancer: Current status and future perspectives
Lung cancer has the highest incidence of morbidity and mortality throughout the globe. A large number of patients are diag...