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Ca2+-activated K+ channels modulate membrane potential in the human parathyroid cell: Possible role in exocytosis
Ca2+-activated K+ channels modulate membrane potential in the human parathyroid cell: Possible role in exocytosis
The relationships between parathyroid hormone (PTH) secretion and parathyroid cell membrane potential, including the ident...
Circular RNA DLGAP4 alleviates sevoflurane-induced neurotoxicity by regulating miR-9-5p/Sirt1/BDNF pathway
Circular RNA DLGAP4 alleviates sevoflurane-induced neurotoxicity by regulating miR-9-5p/Sirt1/BDNF pathway
Sevoflurane is an inhalational anesthetic agent that is commonly used in neonatal and pediatric surgery due to its low blo...
Cell death classification: A new insight based on molecular mechanisms
Cell death classification: A new insight based on molecular mechanisms
For a long Continuum of time, the phenomenon of cell death was known as an ambiguous and mysterious process that sporadica...
Capsaicin inhibits A7r5 cell senescence via the mitochondrial carrier protein Slc25a12
Capsaicin inhibits A7r5 cell senescence via the mitochondrial carrier protein Slc25a12
Aging of vascular smooth muscle cells (VSMCs) is the principal factor responsible for the loss of vascular function, and c...
Cardiac ischemic preconditioning promotes cMyBP-C phosphorylation by inhibiting the calpain-mediated proteolysis
Cardiac ischemic preconditioning promotes cMyBP-C phosphorylation by inhibiting the calpain-mediated proteolysis
Myocardial infarction (MI) is a clinically important consequence of myocardial ischemia or infarction, and is a major caus...
ADAMTS-1 has nuclear localization in cells with epithelial origin and leads to decreased cell migration
ADAMTS-1 has nuclear localization in cells with epithelial origin and leads to decreased cell migration
The ADAMTS proteinases belong to a family of 19 metalloproteinases [1,2] that participate in extracellular matrix processi...
Hypoxia promotes the growth and metastasis of ovarian cancer cells by suppressing ferroptosis via upregulating SLC2A12
Hypoxia promotes the growth and metastasis of ovarian cancer cells by suppressing ferroptosis via upregulating SLC2A12
SlC2A12 (Bioss, Boston, USA, bs-2540, 1:2000), GPX4 (ABclonal, Wuhan, China, A11243, 1:1000), HIF-1A (Abcam, Cambridge, UK...
The anti-SARS-CoV-2 BNT162b2 vaccine suppresses mithramycin-induced erythroid differentiation and expression of embryo-fetal globin genes in human erythroleukemia K562 cells
The anti-SARS-CoV-2 BNT162b2 vaccine suppresses mithramycin-induced erythroid differentiation and expression of embryo-fetal globin genes in human erythroleukemia K562 cells
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causative of the ongoing coronavirus disease 2019 (COV...
Quercitrin attenuates the progression of osteoarthritis via inhibiting NF-κB signaling pathways and enhance glucose transport capacity
Quercitrin attenuates the progression of osteoarthritis via inhibiting NF-κB signaling pathways and enhance glucose transport capacity
Osteoarthritis (OA) is a common musculoskeletal disorder that impairs function and reduces the quality of life [1]. Clinic...
Reactive oxygen species downregulate dystroglycans in the megakaryocytes of rats with arterial hypertension
Reactive oxygen species downregulate dystroglycans in the megakaryocytes of rats with arterial hypertension
Systemic arterial hypertension characterized by persistently high blood pressure is the main risk factor for cardiovascula...
GPx1 promotes hypertrophic differentiation of chondrocytes through modulation of akt signaling in a non-monotonic manner
GPx1 promotes hypertrophic differentiation of chondrocytes through modulation of akt signaling in a non-monotonic manner
The longitudinal growth of long bones is driven by endochondral ossification in growth plate [1]. This process begins with...
Combined inhibition of pyruvate dehydrogenase kinase 1 and hexokinase 2 induces apoptsis in non-small cell lung cancer cell models
Combined inhibition of pyruvate dehydrogenase kinase 1 and hexokinase 2 induces apoptsis in non-small cell lung cancer cell models
Cancer cells often exhibit a metabolic shift that allows them to produce energy through glycolysis even in the presence of...
Calcineurin suppresses rat H9c2 cardiomyocyteprotective autophagy under chronic intermittent hypoxia by downregulating the AMPK pathway
Calcineurin suppresses rat H9c2 cardiomyocyteprotective autophagy under chronic intermittent hypoxia by downregulating the AMPK pathway
Obstructive sleep apnea syndrome (OSAS) is an emerging yet prevalent disease worldwide. It is associated with multiple com...
Knockdown of Chronophage in the nervous system mimics features of neurodevelopmental disorders caused by BCL11A/B variants
Knockdown of Chronophage in the nervous system mimics features of neurodevelopmental disorders caused by BCL11A/B variants
Neurodevelopmental disorders (NDD) include intellectual disability (ID), autism spectrum disorder (ASD), attention deficit...
Involvement of estrogen receptor activation in kaempferol-3-O-glucoside's protection against aging-related cognition impairment and microglial inflammation
Involvement of estrogen receptor activation in kaempferol-3-O-glucoside's protection against aging-related cognition impairment and microglial inflammation
Dementia is a neurocognitive disorder characterized by deterioration in memory and thinking that severely interferes with ...
Corrigendum to “iPS-derived neural stem cells for disease modeling and evaluation of therapeutics for mucopolysaccharidosis type II” [Exp. Cell Res. 412, Issue 1, 1 March 2022, 113007]
Corrigendum to “iPS-derived neural stem cells for disease modeling and evaluation of therapeutics for mucopolysaccharidosis type II” [Exp. Cell Res. 412, Issue 1, 1 March 2022, 113007]
Volume 433, Issue 2, 15 December 2023, 113808Author links open overlay panelJunjie Hong a b, Yu-Shan Cheng a, Shu Yang a, ...
Corrigendum to ‘Optimizing combination of liver-enriched transcription factors and nuclear receptors simultaneously favors ammonia and drug metabolism in liver cells’ [Exp. Cell Res. 2018 Jan 15; 362(2):504–514./ PMID: 29253535]
Corrigendum to ‘Optimizing combination of liver-enriched transcription factors and nuclear receptors simultaneously favors ammonia and drug metabolism in liver cells’ [Exp. Cell Res. 2018 Jan 15; 362(2):504–514./ PMID: 29253535]
Volume 433, Issue 2, 15 December 2023, 113809Author links open overlay panelYongfa Su, Zhanfei Chen, Linlin Yan, Fen Lian,...
PKCζ phosphorylates VASP to mediate chemotaxis in breast cancer cells
PKCζ phosphorylates VASP to mediate chemotaxis in breast cancer cells
Breast cancer is a highly heterogeneous malignancy in terms of molecular characteristics and clinical phenotypes. Similar ...
Rapamycin promotes hematoma resorption and enhances endothelial cell function by suppressing the mTOR/STAT3 signaling in chronic subdural hematoma
Rapamycin promotes hematoma resorption and enhances endothelial cell function by suppressing the mTOR/STAT3 signaling in chronic subdural hematoma
Chronic subdural hematoma (CSDH) represents one of the most frequent neurosurgical conditions especially prevalent in elde...
miR-212/132 attenuates OVA-induced airway inflammation by inhibiting mast cells activation through MRGPRX2 and ASAP1
miR-212/132 attenuates OVA-induced airway inflammation by inhibiting mast cells activation through MRGPRX2 and ASAP1
Asthma is a heterogeneous, chronic disease of the lower airways associated with airway hyper‐reactivity, bronchoconstricti...
Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase
Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase
Having sufficient muscle mass and strength is associated with low morbidity and mortality [1,2]. An individual's muscle ma...
SENP1-mediated SUMOylation of SIRT1 affects glioma development through the NF-κB pathway
SENP1-mediated SUMOylation of SIRT1 affects glioma development through the NF-κB pathway
Malignant primary brain cancer is one of the most difficult cancers to treat, with a 5-year overall survival no greater th...
Mitochondrial response of glioma cells to temozolomide
Mitochondrial response of glioma cells to temozolomide
Cancer tissue presents complex metabolic adaptations to sustain cellular growth [1]. The importance of mitochondrial funct...
“The recent development of carbon-based nanoparticles as a novel approach to skin tissue care and management - A review”
“The recent development of carbon-based nanoparticles as a novel approach to skin tissue care and management - A review”
Skin is the largest organ in the human body and the first physical barrier, which protects the human body against external...
Microarray analysis identifies human apoA-IMilano and apoA-II as determinants of the liver gene expression related to lipid and energy metabolism
Microarray analysis identifies human apoA-IMilano and apoA-II as determinants of the liver gene expression related to lipid and energy metabolism
Dyslipidemia plays an important pathogenic role in the development of atherosclerosis, the dominant cause of cardiovascula...
Mechanism of lncRNA HOTAIR in attenuating cardiomyocyte pyroptosis in mice with heart failure via the miR-17-5p/RORA axis
Mechanism of lncRNA HOTAIR in attenuating cardiomyocyte pyroptosis in mice with heart failure via the miR-17-5p/RORA axis
Heart failure (HF) is a complex clinical syndrome characterized by abnormal cardiac structure or function, resulting in di...
3DCNAS: A universal method for predicting the location of fluorescent organelles in living cells in three-dimensional space
3DCNAS: A universal method for predicting the location of fluorescent organelles in living cells in three-dimensional space
The cell is a complex system composed of dozens of key organelles and thousands of other structures, intricately interconn...
Human visceral adipose tissue microvascular endothelial cell isolation and establishment of co-culture with white adipocytes to analyze cell-cell communication
Human visceral adipose tissue microvascular endothelial cell isolation and establishment of co-culture with white adipocytes to analyze cell-cell communication
Adipose tissue is considered as a major metabolic and endocrine organ, and is classified into two main subtypes, brown adi...
Squalene epoxidase promotes breast cancer progression by regulating CCNB1 protein stability
Squalene epoxidase promotes breast cancer progression by regulating CCNB1 protein stability
Breast cancer (BC), a highly prevalent malignancy worldwide, has experienced a regrettable rise in morbidity rates in rece...
Alcohol dehydrogenase 1 is a tubular mitophagy-dependent apoptosis inhibitor against septic acute kidney injury
Alcohol dehydrogenase 1 is a tubular mitophagy-dependent apoptosis inhibitor against septic acute kidney injury
Acute kidney injury (AKI) is the most common complication of sepsis which leads to high rate of mortality and morbidity wo...
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