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Genome-wide identification and expression analysis of phosphate-sensing SPX proteins in oats
1 IntroductionGlobal climate changes, such as soil salinization, drought, extreme temperatures, etc., have worsened over t...
Case report: A case of holocarboxylase synthetase deficiency with respiratory tract as the initial symptom
1 IntroductionHolocarboxylase synthetase (HLCS) deficiency (HLCSD), a rare autosomal recessive metabolic disorder, disrupt...
Structure-adaptive canonical correlation analysis for microbiome multi-omics data
1 IntroductionThe human microbiome is the collection of microorganisms and their genetic makeup associated with the human ...
Comparative study of the three-dimensional genomes of granulosa cells in germinal vesicle and metaphase II follicles
1 IntroductionFemale infertility presents itself as a multifaceted health concern, resulting from single or multiple facto...
DElite: a tool for integrated differential expression analysis
1 IntroductionOne of the main goals of transcriptome analysis is to identify significant differences in gene expression pa...
Editorial: Diagnosis and identification of novel disorders and ultra-rare disorders in science and clinical routine
Hacer Durmus, Istanbul Faculty of Medicine, Department of Neurology, Istanbul, TurkeyThe application of rapid exome sequen...
Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer
IntroductionColorectal cancer (CRC) poses a significant global health challenge, with 1.8 million new diagnoses and 1 mill...
Corrigendum: Serum exosomal circular RNA expression profile and regulative role in proliferative diabetic retinopathy
PAGE \* Arabic \* MERGEFORMAT 3In the published article, there was an error in [FIGURE 7 | Function of circFndc3b in angio...
Causal effect of waist-to-hip ratio on non-alcoholic fatty liver disease: a mendelian randomization study
1 IntroductionNon-alcoholic fatty liver disease (NAFLD), a prevalent chronic liver disease globally, imposes a considerabl...
MiR-99a-5p up-regulates LDLR and functionally enhances LDL-C uptake via suppressing PCSK9 expression in human hepatocytes
1 IntroductionHypercholesterolemia, especially elevated plasma low-density lipoprotein cholesterol (LDL-C) levels, is know...
The genetics of resistance to infectious pancreatic necrosis virus in rainbow trout unveiled through survival and virus load data
1 IntroductionInfections and diseases pose the biggest threats to the Norwegian rainbow trout industry, with an annual pro...
Editorial: Advances in crop breeding for abiotic stress tolerance
Global climate change, which includes drought, extreme temperatures, and adverse soil conditions such as salinity and heav...
Case report: Novel variants cause developmental and epileptic encephalopathy in three unrelated families from Mali
IntroductionDevelopmental and epileptic encephalopathies (DEEs) are a group of neurological disorders characterized by ear...
Subtyping colorectal cancer based on septic shock-associated genes: prognosis and immune characteristics
IntroductionSepsis is a complication resulting from a host’s dysregulated response to a primary infection, often leading t...
Gut Microbiota’s role in lipoma development: evidence from mendelian randomization
1 IntroductionLipoma is a prevalent subcutaneous benign tumor arising from adipose tissue, typically surrounded by a thin ...
Enhanced visualization of microbiome data in repeated measures designs
1 IntroductionCross-sectional studies of the human microbiome have identified a wide range of outcomes and exposures assoc...
A scoring model based on bacterial lipopolysaccharide-related genes to predict prognosis in NSCLC
BackgroundLung cancer, or bronchogenic carcinoma, is the leading cause of oncological mortality globally and originates fr...
Multi-fusion strategy network-guided cancer subtypes discovering based on multi-omics data
1 IntroductionCancer is a heterogeneous disease characterized by diverse pathogenic mechanisms and clinical features (Wang...
Multi-omics insights implicate the remodeling of the intestinal structure and microbiome in aging
IntroductionThe incidence of various tumors and chronic diseases grows along with the aging process and longer life expect...
Genetic screening of α-thalassemia fusion gene using routine flow-through hybridization
Introductionα-Thalassemia is a common monogenic disease characterized by decreased or absent synthesis of the α-globin gen...
Comprehensive analysis of molecular mechanisms underlying kidney stones: gene expression profiles and potential diagnostic markers
1 IntroductionIn the past 30 years, the incidence of kidney stones has significantly increased due to environmental change...
What are microsatellites and how to choose the best tool: a user-friendly review of SSR and 74 SSR mining tools
1 IntroductionMicrosatellites (MS) are highly polymorphic regions of DNA widely employed in fields such as oncology, foren...
Integrative analysis of single-cell transcriptomic and multilayer signaling networks in glioma reveal tumor progression stage
1 IntroductionGlioma is the most common type of central nervous system tumor and is derived from non-neuronal glial cells....
Editorial: Plant biodiversity and genetic resources: their utilization for crop improvement
As global agriculture faces unprecedented challenges-from climate change to food insecurity-plant 14 biodiversity and gene...
AI-enabled pipeline for virus detection, validation, and SNP discovery from next-generation sequencing data
1 IntroductionViruses pose significant threats to human health, agriculture, and the environment, causing a wide range of ...