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MicroRNAs in obesity, sarcopenia, and commonalities for sarcopenic obesity: a systematic review
MicroRNAs in obesity, sarcopenia, and commonalities for sarcopenic obesity: a systematic review
Abstract Sarcopenic obesity is a distinct condition of sarcopenia in the context of obesity, with the cumulative health ri...
Intramuscular and intratendinous placenta‐derived mesenchymal stromal‐like cell treatment of a chronic quadriceps tendon rupture
Intramuscular and intratendinous placenta‐derived mesenchymal stromal‐like cell treatment of a chronic quadriceps tendon rupture
Abstract Background Quadriceps tendon ruptures (QTRs) are rare but debilitating injuries, often associated with chronic me...
Muscle strength and muscle mass as predictors of hospital length of stay in patients with moderate to severe COVID‐19: a prospective observational study
Muscle strength and muscle mass as predictors of hospital length of stay in patients with moderate to severe COVID‐19: a prospective observational study
Abstract Background Strength and muscle mass are predictors of relevant clinical outcomes in critically ill patients, but ...
Immunometabolic signatures predict recovery from thyrotoxic myopathy in patients with Graves' disease
Immunometabolic signatures predict recovery from thyrotoxic myopathy in patients with Graves' disease
Abstract Background Thyroid hormone excess induces protein energy wasting, which in turn promotes muscle weakness and bone...
Cancer cachexia: the elephant in the room?
Cancer cachexia: the elephant in the room?
When confronting new and complex challenges, I often think of the parable of the blind men and the elephant. In meeting an...
Absolute and relative grip strength as predictors of cancer: prospective cohort study of 445 552 participants in UK Biobank
Absolute and relative grip strength as predictors of cancer: prospective cohort study of 445 552 participants in UK Biobank
Abstract Background Reduced muscular strength, as measured by absolute grip strength, has been associated with increased r...
The contributory role of vascular health in age‐related anabolic resistance
The contributory role of vascular health in age‐related anabolic resistance
Abstract Sarcopenia, or the age-related loss of skeletal muscle mass and function, is an increasingly prevalent condition ...
Associations between frailty trajectories and frailty status and adverse outcomes in community‐dwelling older adults
Associations between frailty trajectories and frailty status and adverse outcomes in community‐dwelling older adults
Abstract Background The association between frailty and adverse outcomes has been clearly defined. Frailty is associated w...
Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients
Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients
Abstract Background Cachexia-associated skeletal muscle wasting or ‘sarcopenia’ is highly prevalent in ovari...
Serum carnitine as a biomarker of sarcopenia and nutritional status in preoperative gastrointestinal cancer patients
Serum carnitine as a biomarker of sarcopenia and nutritional status in preoperative gastrointestinal cancer patients
Abstract Background Sarcopenia is an important factor in the postoperative outcome of gastrointestinal cancer patients. Ho...
Histomorphological and inflammatory changes of white adipose tissue in gastrointestinal cancer patients with and without cachexia
Histomorphological and inflammatory changes of white adipose tissue in gastrointestinal cancer patients with and without cachexia
Abstract Background During cancer cachexia, several alterations occur in peripheral tissues, and the adipose tissue may be...
Identification of traumatic acid as a potential plasma biomarker for sarcopenia using a metabolomics‐based approach
Identification of traumatic acid as a potential plasma biomarker for sarcopenia using a metabolomics‐based approach
Abstract Background The pathogenesis of sarcopenia is complex and has not been well explored. Identifying biomarkers is a ...
Extracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle
Extracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle
Abstract Background Cachexia, a syndrome frequently occurring in cancer patients, is characterized by muscle wasting, alte...
Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice
Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice
Abstract Background Muscular dystrophy (MD) causes muscle wasting and is often lethal in patients due to a lack of proven ...
Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2021
Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2021
Abstract The Journal of Cachexia, Sarcopenia and Muscle (JCSM) aims to publish articles with relevance to wasting disorder...
Validation of a proxy‐reported SARC‐F questionnaire for current and retrospective screening of sarcopenia‐related functional impairments
Validation of a proxy‐reported SARC‐F questionnaire for current and retrospective screening of sarcopenia‐related functional impairments
Abstract Background The strength, assistance walking, rise from a chair, climb stairs, and falls (SARC-F) questionnaire is...
Cachectic muscle wasting in acute myeloid leukaemia: a sleeping giant with dire clinical consequences
Cachectic muscle wasting in acute myeloid leukaemia: a sleeping giant with dire clinical consequences
Abstract Acute myeloid leukaemia (AML) is a haematological malignancy with poor survival odds, particularly in the older (...
Sonographic assessment of low muscle quantity identifies mortality risk during COVID‐19: a prospective single‐centre study
Sonographic assessment of low muscle quantity identifies mortality risk during COVID‐19: a prospective single‐centre study
Abstract Background Assessment of muscle quantity by sonographic muscle indices could help identify patients at risk for f...
Cannabinoid interventions for improving cachexia outcomes in cancer: a systematic review and meta‐analysis
Cannabinoid interventions for improving cachexia outcomes in cancer: a systematic review and meta‐analysis
Abstract Cancer-associated cachexia (CAC) is a wasting syndrome characterized by involuntary weight loss and anorexia. Cle...
Associations of osteoporosis and sarcopenia with frailty and multimorbidity among participants of the Hertfordshire Cohort Study
Associations of osteoporosis and sarcopenia with frailty and multimorbidity among participants of the Hertfordshire Cohort Study
Abstract Background Ageing is commonly associated with sarcopenia (SP) and osteoporosis (OP), both of which are associated...
Systemic ablation of vitamin D receptor leads to skeletal muscle glycogen storage disorder in mice
Systemic ablation of vitamin D receptor leads to skeletal muscle glycogen storage disorder in mice
Abstract Background Vitamin D deficiency leads to pathologies of multiple organ systems including skeletal muscle. Patient...
Msi2‐mediated MiR7a‐1 processing repression promotes myogenesis
Msi2‐mediated MiR7a‐1 processing repression promotes myogenesis
Abstract Background Most of the microRNAs (MiRs) involved in myogenesis are transcriptional regulated. The role of MiR bio...
The metabolic landscape in chronic rotator cuff tear reveals tissue‐region‐specific signatures
The metabolic landscape in chronic rotator cuff tear reveals tissue‐region‐specific signatures
Abstract Background Degeneration of shoulder muscle tissues often result in tearing, causing pain, disability and loss of ...
Muscle‐to‐fat ratio identifies functional impairments and cardiometabolic risk and predicts outcomes: biomarkers of sarcopenic obesity
Muscle‐to‐fat ratio identifies functional impairments and cardiometabolic risk and predicts outcomes: biomarkers of sarcopenic obesity
Abstract Background Sarcopenic obesity aims to capture the risk of functional decline and cardiometabolic diseases, but it...
Facioscapulohumeral dystrophy weakened sarcomeric contractility is mimicked in induced pluripotent stem cells‐derived innervated muscle fibres
Facioscapulohumeral dystrophy weakened sarcomeric contractility is mimicked in induced pluripotent stem cells‐derived innervated muscle fibres
Abstract Background Facioscapulohumeral dystrophy (FSHD) is a late-onset autosomal dominant form of muscular dystrophy inv...
Effects of AST‐120 on muscle health and quality of life in chronic kidney disease patients: results of RECOVERY study
Effects of AST‐120 on muscle health and quality of life in chronic kidney disease patients: results of RECOVERY study
Abstract Background The prevalence of sarcopenia is increased with declining renal function. Elevated serum indoxyl sulfat...
Epigenome‐wide association study of sarcopenia: findings from the Hertfordshire Sarcopenia Study (HSS)
Epigenome‐wide association study of sarcopenia: findings from the Hertfordshire Sarcopenia Study (HSS)
Abstract Background Sarcopenia is the age-related loss of muscle mass, strength, and function. Epigenetic processes such a...
Development and validation of a Modified Patient‐Generated Subjective Global Assessment as a nutritional assessment tool in cancer patients
Development and validation of a Modified Patient‐Generated Subjective Global Assessment as a nutritional assessment tool in cancer patients
Abstract Background Completing Patient-Generated Subjective Global Assessment (PG-SGA) questionnaires is time consuming. T...
Twelve‐year sarcopenia trajectories in older adults: results from a population‐based study
Twelve‐year sarcopenia trajectories in older adults: results from a population‐based study
Abstract Background The dynamic nature of sarcopenia, including possible transitions between its different stages, is curr...
Microproteins in skeletal muscle: hidden keys in muscle physiology
Microproteins in skeletal muscle: hidden keys in muscle physiology
Abstract Recent advances in the transcriptomics, translatomics, and proteomics have led us to the exciting new world of fu...
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