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Metabolism, mitochondria and metastasis in kidney cancer
A study published in Nature investigating tumour metabolism in kidney cancers provides insight into the influence of mitoc...
Disruption of circadian rhythm as a potential pathogenesis of nocturia
Disruption of circadian rhythm as a potential pathogenesis of nocturia
Increasing evidence suggested the multifactorial nature of nocturia, but the true pathogenesis of this condition still rem...
Molecular imaging of renal cell carcinomas: ready for prime time
Molecular imaging of renal cell carcinomas: ready for prime time
The clinical diagnosis of renal cell carcinoma (RCC) is constantly evolving. Diagnostic imaging of RCC relying on enhanced...
HSD3B1, prostate cancer mortality and modifiable outcomes
HSD3B1, prostate cancer mortality and modifiable outcomes
Androgen receptor stimulation by testosterone and dihydrotestosterone is crucial for prostate cancer progression. Despite ...
177Lu-PSMA-617 extends progression-free survival in taxane-naive mCRPC
A new phase III, randomized, controlled trial was carried out to assess the efficacy of 177Lu-PSMA-617 in patients with ta...
Tivozanib monotherapy outperforms combination therapy in post-ICI RCC
The multicentre, randomized, phase III trial TiNivo-2 was conducted to assess the efficacy of the vascular endothelial gro...
The urge to advance: ICS 2024 drives innovation in continence care
The urge to advance: ICS 2024 drives innovation in continence care
From 23 to 25 October 2024, Madrid hosted the 54th edition of the annual meeting of the International Continence Society (...
Exploring the impact of lipid stress on sperm cytoskeleton: insights and prospects
Exploring the impact of lipid stress on sperm cytoskeleton: insights and prospects
The decline in male fertility correlates with the global rise in obesity and dyslipidaemia, representing significant publi...
20 years of ‘spilling the tea’ in urology
20 years of ‘spilling the tea’ in urology
When Nature Clinical Practice Urology launched in 2004, we could not have foreseen the ways in which our field has transfo...
Pre-treatment metastatic biopsy: a step towards precision oncology for urothelial cancer
Pre-treatment metastatic biopsy: a step towards precision oncology for urothelial cancer
Early metastatic spread and clonal expansion of individual mutations result in a heterogeneous tumour landscape in metasta...
Prostate cancer in transgender women — challenges in research and clinical care
Literature about prostate cancer in transgender women is growing, but many questions remain unanswered. Unique challenges ...
Author Correction: Metaverse in surgery — origins and future potential
These authors contributed equally: Enrico Checcucci, Giovanni Cacciamani, Francesco Porpiglia.Department of Surgery, Candi...
Racial disparities in prostate cancer in the UK and the USA: similarities, differences and steps forwards
In the USA, Black men are approximately twice as likely to be diagnosed with and to die of prostate cancer than w...
Disulfidptosis-related genes could target personalized therapy and aid prognostics
Disulfidptosis is a programmed cell death pathway in prostate cancer. A study in Scientific Reports has investigated the r...
Source renewal is essential for mouse TIME models
A study in Scientific Reports has used isotransplantation to examine the effect of mouse breeding nuclei in prostate cance...
Nature Reviews Urology: evolving with the field for 20 years
Nature Reviews Urology: evolving with the field for 20 years
For the past 20 years, Nature Reviews Urology has evolved alongside the field, reflecting a shift towards basic research a...
Looking backwards and looking forwards: the view from the middle
Looking backwards and looking forwards: the view from the middle
Over the past 20 years, Nature Reviews Urology has been at the forefront of developments in the field — from champio...
Cell death score predicts prostate cancer metastasis and immunotherapy response
Intermediate-risk and high-risk localized prostate cancer are treatable, but metastases (in ~30% of patients) often lead t...
Immunoliposome targeting IL-30
Proof of concept has been demonstrated for a modern and safe immuno-nanotherapy for prostate cancer in a study published i...
Interactions between androgen and IGF1 axes in prostate tumorigenesis
Interactions between androgen and IGF1 axes in prostate tumorigenesis
Androgen signalling through the androgen receptor (AR) is essential for prostate tumorigenesis. However, androgen...
Plant-based diets and urological health
Plant-based diets and urological health
Plant-based diets have grown in popularity owing to multiple health and environmental benefits. Some evidence suggests tha...
Pimping in the clinical learning environment: representation of women in surgery
Women are under-represented in surgery and are particularly subject to the intrinsically gendered practice of pimping in t...
Electrical stimulation for the hypocontractile bladder
The incidence of detrusor underactivity is projected to rise owing to an ageing population and the increasing prevalence o...
Metaverse in surgery — origins and future potential
Metaverse in surgery — origins and future potential
The metaverse refers to a collective virtual space that combines physical and digital realities to create immersive, inter...
Measuring and improving the cradle-to-grave environmental performance of urological procedures
Measuring and improving the cradle-to-grave environmental performance of urological procedures
An urgent need for societal transformation exists to reduce the environmental impact of humanity, because environmental he...
Urinary bladder transplantation in humans — current status and future perspectives
Urinary bladder transplantation in humans — current status and future perspectives
Urinary bladder vascularized allograft transplantation in humans is currently extensively being investigated worldwide, ow...
Gut microbiota influence bladder tumour development
New research, published in Nature, shows that gut microbiota carcinogen metabolism could contribute to chemical-induced ca...
Prescribing clinician specialty influences adherence to PrEP
In a new study published in JAMA Internal Medicine, the association between patients abandoning or reversing the pre-expos...
Intralesional heterogeneity on PSMA PET–CT predicts mCRPC outcomes
Intra-tumour heterogeneity in patients with metastatic castration-resistant prostate cancer (mCRPC) poses a challenge to t...
piRNA pathway disruption in human infertility
PIWI-interacting RNAs (piRNAs) are crucial regulators of gene expression in male germ cells. In a study published in Natur...
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