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Biological determinants of PSMA expression, regulation and heterogeneity in prostate cancer
Biological determinants of PSMA expression, regulation and heterogeneity in prostate cancer
Prostate-specific membrane antigen (PSMA) is an important cell-surface imaging biomarker and therapeutic target in prostat...
Optimizing cystoscopy and TURBT: enhanced imaging and artificial intelligence
Optimizing cystoscopy and TURBT: enhanced imaging and artificial intelligence
Diagnostic cystoscopy in combination with transurethral resection of the bladder tumour are the standard for the diagnosis...
Alternative promoters activate oncogenic programmes
Use of alternative promoters by oncogene transcription factors increases as prostate tumours progress from benign to metas...
Microplastics in the penis
The presence of microplastics has been found in human penile tissue. This discovery has implications for male fertility an...
Increased xenokidney survival
Survival of xenograft kidneys in allosensitized recipients is extended when using kidneys from pigs with multiple genetic ...
Syphilis on the rise — a need for alternative therapies and vaccines
Syphilis, caused by the bacterium Treponema pallidum subsp. pallidum (TPA), re-emerged as a global health problem in the t...
Krause corpuscles act as genital vibration detectors
First described in the 1850s by Wilhelm Krause, the function and physiological functions of the sensory structures that be...
Author Correction: Advances in sliding clip renorrhaphy for partial nephrectomy
Department of Urology, Western Health, Melbourne, Victoria, AustraliaDavid Homewood, Nicholas Tan, Niall M. Corcoran &...
Advances in sliding clip renorrhaphy for partial nephrectomy
Partial nephrectomy aims to provide both effective oncological management and renal function preservation. Surgical compli...
De-clear cell differentiated renal cell carcinoma — a new therapeutic target
De-clear cell differentiated renal cell carcinoma — a new therapeutic target
Reprogrammed metabolism has been long recognized as a driver of kidney cancer progression, prompting efforts to develop me...
Renal mass biopsy — a practical and clinicopathologically relevant approach to diagnosis
Renal mass biopsy — a practical and clinicopathologically relevant approach to diagnosis
Advancements in imaging modalities have increased the frequency of renal mass discovery. Imaging has typically been consid...
Progression-free survival end points in prostate cancer: are we truly making progress
Recently, several therapeutic strategies in prostate cancer have been granted regulatory approval based on progression-fre...
The bladder tumour microbiome and BCG response
BCG treatment is the gold-standard therapy for high-grade intermediate-risk and high-risk non-muscle-invasive bladder canc...
A new signalling-based system for germ cell reprogramming
Differentiation of human primordial germ cells (hPGCs) to mitotic spermatogonia and oogonia occurring through epigenetic r...
A prompt-based stewardship to reduce extended-spectrum antibiotic treatment in UTI
Hospitalized patients with urinary tract infection (UTI) often receive treatment with extended-spectrum antibiotics while ...
Single-cell penile cancer atlas to identify disease drivers
Penile squamous cell carcinoma (PSCC) can be classified into human papilloma virus-positive (HPV+) and HPV-independent (HP...
Promising efficacy of UTI vaccines as an alternative to antibiotics
Antibiotics are the mainstay prophylaxis and treatment for recurrent urinary tract infections (UTIs). However, antibiotic ...
Engaging medical students in urological academic research
Engaging medical students in urological academic research
Medical students provide an unmistakable contribution to clinical research, owing to a diverse skill set, spanning from da...
Rediscovering citrate as a biomarker for prostate cancer
Rediscovering citrate as a biomarker for prostate cancer
For many years, PSA has been the most commonly used biomarker for prostate cancer screening and diagnosis. Although serum ...
Nocturia and obstructive sleep apnoea
Nocturia and obstructive sleep apnoea
Nocturia, the need to urinate at night, is a common symptom in patients with obstructive sleep apnoea (OSA). Continuous po...
Overall survival with adjuvant pembrolizumab in renal cell carcinoma — the shock of the lightning
Overall survival with adjuvant pembrolizumab in renal cell carcinoma — the shock of the lightning
In the KEYNOTE-564 trial, patients with resected clear cell renal cell carcinoma at a high risk of relapse experienced dis...
Preclinical models of bladder cancer: BBN and beyond
Preclinical models of bladder cancer: BBN and beyond
Preclinical modelling is a crucial component of advancing the understanding of cancer biology and therapeutic development....
AUA24 — pioneering shared decision-making and patient engagement strategies
AUA24 — pioneering shared decision-making and patient engagement strategies
Urologists, scientists and other professionals in the urology field converged in San Antonio, Texas, to attend the 119th e...
Promoting the health of men of all backgrounds: educating ourselves to build trust and improve care
Specific issues affect the treatment of urological cancer and survivorship in gay and bisexual men. Creating an accepting ...
Overcoming barriers in cancer care for gender minorities
As the population of gender minorities grows in the setting of rising incidence of cancers globally, health-care professio...
Chromosome segregation in SCNT oocytes
The possibility of men in same-sex relationships and people who do not have their own eggs having biological children has ...
Asexuality: the invisible orientation
Asexuality is often neglected in education and conversations around sexuality, making it essentially an ‘invisible o...
Elevated periprostatic androgens, sneaky testosterone and its implications
Elevated periprostatic androgens, sneaky testosterone and its implications
A subset of men with prostate cancer have elevated periprostatic androgens compared with levels in peripheral blood (terme...
Current and emerging strategies to curb antibiotic-resistant urinary tract infections
Current and emerging strategies to curb antibiotic-resistant urinary tract infections
Rising rates of antibiotic resistance in uropathogenic bacteria compromise patient outcomes and prolong hospital stays. Co...
We all get erections — de-gendering sexual arousal dysfunction in the ICD
We all get erections — de-gendering sexual arousal dysfunction in the ICD
Definitions of sexual arousal dysfunction in the International Classification of Diseases use sex-specific binaries that o...
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