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The 5th European pharmacovigilance congress: speaker abstracts
The 5th European pharmacovigilance congress: speaker abstracts
Access to society journal content varies across our titles. If you have access to a journal via a society or association ...
Do women with venous thromboembolism bleed more than men during anticoagulation? Data from the real-life, prospective START-Register
Do women with venous thromboembolism bleed more than men during anticoagulation? Data from the real-life, prospective START-Register
Background:Venous thromboembolism (VTE) is a frequent and serious disease that requires immediate and long-term anticoagul...
Effectiveness of drug postmarketing all-case surveillance as a safety measure in Japan
Effectiveness of drug postmarketing all-case surveillance as a safety measure in Japan
Introduction:The drug pharmacovigilance system in Japan is similar to those in the European Union (EU) and the United Stat...
The danger of diazoxide in the neonatal intensive care unit
The danger of diazoxide in the neonatal intensive care unit
Background:The most common cause of persistent hypoglycemia in infancy is hyperinsulinemic hypoglycemia. When conservative...
Prospective cohort study of nonspecific deprescribing in older medical inpatients being discharged to a nursing home
Prospective cohort study of nonspecific deprescribing in older medical inpatients being discharged to a nursing home
Background:Older patients from nursing homes are commonly exposed to polypharmacy before a hospital admission. Deprescribi...
Impact of deprescribing dual-purpose medications on patient-related outcomes for older adults near end-of-life: a systematic review and meta-analysis
Impact of deprescribing dual-purpose medications on patient-related outcomes for older adults near end-of-life: a systematic review and meta-analysis
Introduction:The decision to deprescribe medications used for both disease prevention and symptom control (dual-purpose me...
The safety, tolerability and mortality reduction efficacy of remdesivir; based on randomized clinical trials, observational and case studies reported safety outcomes: an updated systematic review and meta-analysis
The safety, tolerability and mortality reduction efficacy of remdesivir; based on randomized clinical trials, observational and case studies reported safety outcomes: an updated systematic review and meta-analysis
Introduction:Remdesivir, an experimental antiviral drug has shown to inhibit severe acute respiratory syndrome coronavirus...
Changes in pharmacovigilance following the end of the Brexit transition
Changes in pharmacovigilance following the end of the Brexit transition
Access to society journal content varies across our titles. If you have access to a journal via a society or association ...
Prediction of potential drug interactions between repurposed COVID-19 and antitubercular drugs: an integrational approach of drug information software and computational techniques data
Prediction of potential drug interactions between repurposed COVID-19 and antitubercular drugs: an integrational approach of drug information software and computational techniques data
Introduction:Tuberculosis is a major respiratory disease globally with a higher prevalence in Asian and African countries ...
Optimising medicines use in older adults with intellectual disability who have epilepsy: challenges and perspectives
Optimising medicines use in older adults with intellectual disability who have epilepsy: challenges and perspectives
1. Shankar, R, Perera, B, Thomas, RH. Epilepsy, an orphan disorder within the neurodevelopmental family. J Neurol Neurosur...
Monitoring the manufacturing and quality of medicines: a fundamental task of pharmacovigilance
Monitoring the manufacturing and quality of medicines: a fundamental task of pharmacovigilance
The collection and assessment of individual case safety reports (ICSRs) is important to detect unknown adverse drug reacti...
Patient harm from cardiovascular medications
Patient harm from cardiovascular medications
BackgroundMedication harm can lead to hospital admission, prolonged hospital stay and poor patient outcomes. Reducing medi...
Inappropriate medications and physical function: a systematic review
Inappropriate medications and physical function: a systematic review
Background and aims:Inappropriate medication prescription is highly prevalent in older adults and is associated with adver...
Fansidar drug induces cytotoxicity in some vital tissues in a rat model: combination defensive effect of selenium and zinc capsules
Fansidar drug induces cytotoxicity in some vital tissues in a rat model: combination defensive effect of selenium and zinc capsules
Aim:Fansidar (FAN) is widely used as an antimalarial drug, but it may cause hepatoxicity, nephrotoxicity, and neurotoxicit...
The safety of ceftolozane-tazobactam for the treatment of acute bacterial infections: a systemic review and meta-analysis
The safety of ceftolozane-tazobactam for the treatment of acute bacterial infections: a systemic review and meta-analysis
Objective(s):The aim of this study was to conduct a meta-analysis to assess the clinical safety of ceftolozane-tazobactam ...
Impact of national valsartan recalls on Veterans’ outcomes
Impact of national valsartan recalls on Veterans’ outcomes
Background and Aims:Chemical impurities discovered in angiotensin receptor blocker (ARB) products in late 2018–2019 result...
Characteristics of voluntary reporting of adverse drug events related to antipsychotics in Australia: 14-year analysis
Characteristics of voluntary reporting of adverse drug events related to antipsychotics in Australia: 14-year analysis
Background:Retrospective analyses of large databases of treated patients can provide useful links to the presence of drug ...
Anticholinergic burden measures and older people’s falls risk: a systematic prognostic review
Anticholinergic burden measures and older people’s falls risk: a systematic prognostic review
Introduction:Several adverse outcomes have been associated with anticholinergic burden (ACB), and these risks increase wit...
Muscle relaxant use and the associated risk of incident frailty in patients with diabetic kidney disease: a longitudinal cohort study
Muscle relaxant use and the associated risk of incident frailty in patients with diabetic kidney disease: a longitudinal cohort study
Background:Patients with diabetic kidney disease (DKD) are at an increased risk of frailty. The exposure to muscle relaxan...
Vaccine Safety Datalink infrastructure enhancements for evaluating the safety of maternal vaccination
Vaccine Safety Datalink infrastructure enhancements for evaluating the safety of maternal vaccination
Background:Identifying pregnancy episodes and accurately estimating their beginning and end dates are imperative for obser...
Tramadol-induced hiccups: a case–noncase study in the European pharmacovigilance database
Tramadol-induced hiccups: a case–noncase study in the European pharmacovigilance database
Background:Hiccups are usually benign and self-limiting, but can sometimes be persistent. If left untreated, they can prov...
Attitudes of ambulatory care older Nepalese patients towards deprescribing and predictors of their willingness to deprescribe
Attitudes of ambulatory care older Nepalese patients towards deprescribing and predictors of their willingness to deprescribe
Introduction:Older adults continue to receive potentially inappropriate medications necessitating the need for medication ...
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