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Diagnostic and therapeutic use of oral micronized progesterone in endocrinology
Diagnostic and therapeutic use of oral micronized progesterone in endocrinology
Progesterone is a natural steroid hormone, while progestins are synthetic molecules. In the female reproductive system, pr...
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
This review aimed to systematically quantify the differences in Metabolic Syndrome (MetS) prevalence across various ethnic...
Endocrine involvement in hepatic glycogen storage diseases: pathophysiology and implications for care
Endocrine involvement in hepatic glycogen storage diseases: pathophysiology and implications for care
Hepatic glycogen storage diseases constitute a group of disorders due to defects in the enzymes and transporters involved ...
A multifaceted and inclusive methodology for the detection of sarcopenia in patients undergoing bariatric surgery: an in-depth analysis of current evidence
A multifaceted and inclusive methodology for the detection of sarcopenia in patients undergoing bariatric surgery: an in-depth analysis of current evidence
Bariatric surgery is widely recognized as the most effective intervention for obesity and offers benefits beyond weight lo...
Diagnosis and management of secondary adrenal crisis
Diagnosis and management of secondary adrenal crisis
Adrenal crisis (AC) is a life threatening acute adrenal insufficiency (AI) episode which can occur in patients with primar...
The changing landscape of acromegaly – an epidemiological perspective
The changing landscape of acromegaly – an epidemiological perspective
Acromegaly is a rare disease and thus challenging to accurately quantify epidemiologically. In this comprehensive literatu...
Subclinical central hypothyroidism in patients with hypothalamic-pituitary disease: does it exist?
Subclinical central hypothyroidism in patients with hypothalamic-pituitary disease: does it exist?
Central hypothyroidism (CH) is characterized by decreased thyroid hormone production due to insufficient stimulation of an...
Adrenal insufficiency in liver diseases - pathophysiology and underlying mechanisms
Adrenal insufficiency in liver diseases - pathophysiology and underlying mechanisms
Relative adrenal insufficiency (RAI) is common in critically ill patients with cirrhosis, but it has been also documented ...
Diabetic Sarcopenia. A proposed muscle screening protocol in people with diabetes
Diabetic Sarcopenia. A proposed muscle screening protocol in people with diabetes
To propose the grounds for “diabetic sarcopenia” as a new comorbidity of diabetes, and to establish a muscle s...
Special features on insulin resistance, metabolic syndrome and vascular complications in hypopituitary patients
Special features on insulin resistance, metabolic syndrome and vascular complications in hypopituitary patients
Pituitary hormone deficiency, hypopituitarism, is a dysfunction resulting from numerous etiologies, which can be complete ...
Androgen deficiency in hypopituitary women: its consequences and management
Androgen deficiency in hypopituitary women: its consequences and management
Women with hypopituitarism have various degrees of androgen deficiency, which is marked among those with combined hypogona...
The effect of bariatric surgery on the expression of gastrointestinal taste receptors: A systematic review
The effect of bariatric surgery on the expression of gastrointestinal taste receptors: A systematic review
Gastrointestinal nutrient sensing via taste receptors may contribute to weight loss, metabolic improvements, and a reduced...
Pulling the trigger: Noncoding RNAs in white adipose tissue browning
Pulling the trigger: Noncoding RNAs in white adipose tissue browning
White adipose tissue (WAT) serves as the primary site for energy storage and endocrine regulation in mammals, while brown ...
Diagnosing and treating the elderly individual with hypopituitarism
Diagnosing and treating the elderly individual with hypopituitarism
Hypopituitarism in the elderly is an underestimated condition mainly due to the non-specific presentation that can be attr...
Cognition and psychological wellbeing in hypopituitary patients
Cognition and psychological wellbeing in hypopituitary patients
Hypopituitarism (HP) frequently occurs in patients presenting with sellar masses and despite recent advances in therapeuti...
Correction to: Potential therapeutic strategies for osteoarthritis via CRISPR/Cas9 mediated gene editing
Correction to: Potential therapeutic strategies for osteoarthritis via CRISPR/Cas9 mediated gene editing
Graphic illustration of CRISPR/Cas9 genome editing for femur and cartilage repairment. Nucleic acids encoding CRISPR/Cas9 ...
The genetics of Graves’ disease
The genetics of Graves’ disease
Graves’ disease (GD) is the commonest cause of hyperthyroidism and has a strong female preponderance. Everyday clini...
Diagnosing and treating anterior pituitary hormone deficiency in pediatric patients
Diagnosing and treating anterior pituitary hormone deficiency in pediatric patients
Hypopituitarism, or the failure to secrete hormones produced by the anterior pituitary (adenohypophysis) and/or to release...
Fertility issues in hypopituitarism
Fertility issues in hypopituitarism
Women with hypopituitarism have lower fertility rates and worse pregnancy outcomes than women with normal pituitary functi...
New insights on diagnosis and treatment of AVP deficiency
New insights on diagnosis and treatment of AVP deficiency
Arginine vasopressin deficiency (AVP-D) is one of the main entities of the polyuria-polydipsia syndrome. Its correct diagn...
Role of CaMKII in diabetes induced vascular injury and its interaction with anti-diabetes therapy
Role of CaMKII in diabetes induced vascular injury and its interaction with anti-diabetes therapy
Diabetes mellitus is a metabolic disorder denoted by chronic hyperglycemia that drives maladaptive structural changes and ...
New findings on brain actions of growth hormone and potential clinical implications
New findings on brain actions of growth hormone and potential clinical implications
Growth hormone (GH) is secreted by somatotropic cells of the anterior pituitary gland. The classical effects of GH compris...
Association between protein undernutrition and diabetes: Molecular implications in the reduction of insulin secretion
Association between protein undernutrition and diabetes: Molecular implications in the reduction of insulin secretion
Undernutrition is still a recurring nutritional problem in low and middle-income countries. It is directly associated with...
Efficacy and tolerability of somatostatin analogues according to gender in patients with neuroendocrine tumors
Efficacy and tolerability of somatostatin analogues according to gender in patients with neuroendocrine tumors
As the incidence of neuroendocrine tumors has been rising, gender differences in epidemiology and clinical behavior have e...
An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications
An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipose tissue, is vital in mo...
Potential therapeutic strategies for osteoarthritis via CRISPR/Cas9 mediated gene editing
Potential therapeutic strategies for osteoarthritis via CRISPR/Cas9 mediated gene editing
Osteoarthritis (OA) is an incapacitating and one of the most common physically degenerative conditions with an assorted et...
New insights in thyroid diagnosis and treatment
New insights in thyroid diagnosis and treatment
The prevalence of thyroid disease continues to rise. As a consequence, the research in the thyroid field has significantly...
Epigenetic programming for obesity and noncommunicable disease: From womb to tomb
Epigenetic programming for obesity and noncommunicable disease: From womb to tomb
Several epidemiological, clinical and experimental studies in recent decades have shown the relationship between exposure ...
Dynamic risk assessment in patients with differentiated thyroid cancer
Dynamic risk assessment in patients with differentiated thyroid cancer
The current approach for patients with differentiated thyroid carcinoma should be individualized according to the risk of ...
Circadian alignment of food intake and glycaemic control by time-restricted eating: A systematic review and meta-analysis
Circadian alignment of food intake and glycaemic control by time-restricted eating: A systematic review and meta-analysis
Daily rhythms of metabolic function are supported by molecular circadian clock systems that are strongly regulated by feed...
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