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Childhood obesity, metabolic syndrome, and oxidative stress: microRNAs go on stage
Childhood obesity, metabolic syndrome, and oxidative stress: microRNAs go on stage
The incidence of childhood obesity and metabolic syndrome has grown notably in the last years, becoming major public healt...
Metabolic phenotyping in people living with obesity: Implications for dietary prevention
Metabolic phenotyping in people living with obesity: Implications for dietary prevention
Given the increasing number of people living with obesity and related chronic metabolic disease, precision nutrition appro...
White adipose tissue mitochondrial bioenergetics in metabolic diseases
White adipose tissue mitochondrial bioenergetics in metabolic diseases
White adipose tissue (WAT) is an important endocrine organ that regulates systemic energy metabolism. In metabolically unh...
Drug-induced hyperinsulinemic hypoglycemia: An update on pathophysiology and treatment
Drug-induced hyperinsulinemic hypoglycemia: An update on pathophysiology and treatment
The initial step for the differential diagnosis of hypoglycemia is to determine whether it is hyperinsulinemic or non hype...
Phenotyping the obesities: reality or utopia?
Phenotyping the obesities: reality or utopia?
In this thematic issue on phenotyping the obesities, prominent international experts offer an insightful and comprehensive...
Beyond glycemia: Comparing tirzepatide to GLP-1 analogues
Beyond glycemia: Comparing tirzepatide to GLP-1 analogues
Glucagon-like peptide-1 receptor analogs (GLP-1 RAs) have been an innovative and instrumental drug class in the management...
Towards precision medicine in non-alcoholic fatty liver disease
Towards precision medicine in non-alcoholic fatty liver disease
Non-Alcoholic Fatty Liver Disease (NAFLD) refers to the accumulation of lipid laden vacuoles in hepatocytes, occurring in ...
Application of radiomics and machine learning to thyroid diseases in nuclear medicine: a systematic review
Application of radiomics and machine learning to thyroid diseases in nuclear medicine: a systematic review
Background: In the last years growing evidences on the role of radiomics and machine learning (ML) applied to different nu...
Ectopic insulinoma: a systematic review
Ectopic insulinoma: a systematic review
Knowledge of ectopic insulinomas comes from single cases. We performed a systematic review through PubMed, Web of Science,...
Precision nutrition for targeting pathophysiology of cardiometabolic phenotypes
Precision nutrition for targeting pathophysiology of cardiometabolic phenotypes
Obesity is a heterogenous disease accompanied by a broad spectrum of cardiometabolic risk profiles. Traditional paradigms ...
Targeting aging with the healthy skeletal system: The endocrine role of bone
Targeting aging with the healthy skeletal system: The endocrine role of bone
Aging is an inevitable biological process, and longevity may be related to bone health. Maintaining strong bone health can...
Hidden chronic metabolic acidosis of diabetes type 2 (CMAD): Clues, causes and consequences
Hidden chronic metabolic acidosis of diabetes type 2 (CMAD): Clues, causes and consequences
Interpretation of existing data revealed that chronic metabolic acidosis is a pathognomic feature for type 2 diabetes (T2D...
Management of radioiodine refractory differentiated thyroid cancer: the Latin American perspective
Management of radioiodine refractory differentiated thyroid cancer: the Latin American perspective
Radioiodine (RAI) refractory differentiated thyroid cancer is an uncommon and challenging situation that requires a multid...
Obesity phenotypes and cardiovascular risk: From pathophysiology to clinical management
Obesity phenotypes and cardiovascular risk: From pathophysiology to clinical management
Obesity epidemic reached the dimensions of a real global health crisis with more than one billion people worldwide living ...
Applying psycho-behavioural phenotyping in obesity characterization
Applying psycho-behavioural phenotyping in obesity characterization
Individual differences in obesity, beyond being explained by metabolic and medical complications, are understood by altera...
Effects of GLP-1 receptor agonists on neurological complications of diabetes
Effects of GLP-1 receptor agonists on neurological complications of diabetes
Emerging evidence suggests that treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) could be an interesti...
Individualised prescription of medications for treatment of obesity in adults
Individualised prescription of medications for treatment of obesity in adults
Obesity continues to increase in prevalence globally, driven by changes in environmental factors which have accelerated th...
Incomplete penetrance and variable expressivity in monogenic diabetes; a challenge but also an opportunity
Incomplete penetrance and variable expressivity in monogenic diabetes; a challenge but also an opportunity
Monogenic Forms of Diabetes (MFD) account for about 3% of all diabetes, and their accurate diagnosis often results in life...
How to address weight regain after bariatric surgery in an individualized way
How to address weight regain after bariatric surgery in an individualized way
Bariatric surgery is the most effective obesity treatment. As a chronic and progressive disease, weight loss response to s...
Towards an adiposity-related disease framework for the diagnosis and management of obesities
Towards an adiposity-related disease framework for the diagnosis and management of obesities
Obesity is a complex disease that relapses frequently and associates with multiple complications that comprise a worldwide...