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Prognostic impact of tumor‑associated stroma in triple-negative breast cancer
Prognostic impact of tumor‑associated stroma in triple-negative breast cancer
To establish the histological categorization of tumor‑associated stroma (TAS) that reflects the biological behavior ...
Factors associated with post acute care utilization after mastectomy for breast cancer patients
Factors associated with post acute care utilization after mastectomy for breast cancer patients
Although the demand for care immediately after mastectomy is rising, and such medical services are referred to as post-acu...
Evidence-based advancements in breast cancer genetic counseling: a review
Evidence-based advancements in breast cancer genetic counseling: a review
Understanding individuals at high risk of breast cancer, as well as patients and survivors, underscores the critical role ...
Gut microbiota and breast cancer: systematic review and meta-analysis
Gut microbiota and breast cancer: systematic review and meta-analysis
The gastrointestinal microbiota can modulate systemic estrogens, potentially influencing estrogen-induced breast neoplasia...
Efficacy and feasibility of neoadjuvant pembrolizumab plus chemotherapy for early-stage triple-negative and estrogen receptor low, HER2-negative breast cancer: a Japanese single-institution real-world study
Efficacy and feasibility of neoadjuvant pembrolizumab plus chemotherapy for early-stage triple-negative and estrogen receptor low, HER2-negative breast cancer: a Japanese single-institution real-world study
Neoadjuvant pembrolizumab plus chemotherapy and adjuvant pembrolizumab have been established as the optimal systemic thera...
A 5-year review of genomic medicine in breast cancer: insights from C-CAT data on 3776 Japanese patients
A 5-year review of genomic medicine in breast cancer: insights from C-CAT data on 3776 Japanese patients
In Japan, despite 5 years since CGP tests were covered by insurance in 2019, low drug accessibility rates remain ...
The role of C1orf50 in breast cancer progression and prognosis
The role of C1orf50 in breast cancer progression and prognosis
Although the prognosis of breast cancer has significantly improved compared to other types of cancer, there are still some...
The complex role of regulatory cells in breast cancer: implication for immunopathogenesis and immunotherapy
The complex role of regulatory cells in breast cancer: implication for immunopathogenesis and immunotherapy
Breast cancers (BCs) are frequently linked to an immunosuppressive microenvironment that facilitates tumor evasion of anti...
Color differences of skin paddles using the free flap for autologous breast reconstruction in Asian patients
Color differences of skin paddles using the free flap for autologous breast reconstruction in Asian patients
In this study, we aimed to evaluate color differences of the skin paddle in autologous breast reconstruction performed usi...
Adjuvant chemotherapy in T1a/bN0 breast cancer with a high 21-gene recurrence score (> 25): a 10-year follow-up in a real-world cohort
Adjuvant chemotherapy in T1a/bN0 breast cancer with a high 21-gene recurrence score (> 25): a 10-year follow-up in a real-world cohort
In ER + /HER2- early breast cancer (BC), 21-Gene Recurrence Score (RS) > 25 indicates high-...
Real-world incidence of and risk factors for abemaciclib-induced interstitial lung disease in Japan: a nested case–control study of abemaciclib-induced interstitial lung disease (NOSIDE)
Real-world incidence of and risk factors for abemaciclib-induced interstitial lung disease in Japan: a nested case–control study of abemaciclib-induced interstitial lung disease (NOSIDE)
The exact incidence of and risk factors for interstitial lung disease (ILD), a serious side effect of abemaciclib, remain ...
Comparative assessment of breast volume using a smartphone device versus MRI
Comparative assessment of breast volume using a smartphone device versus MRI
Assessment of breast volume has a relevance for aesthetic surgery and for the prevention and prediction of breast diseases...
Development and validation of a predictive risk tool for VTE in women with breast cancer under chemotherapy: a cohort study in China
Development and validation of a predictive risk tool for VTE in women with breast cancer under chemotherapy: a cohort study in China
The incidence of venous thromboembolism (VTE) is significantly elevated in breast cancer patients, with a three-to-fourfol...
Comprehensive characterization of invasive mammary carcinoma with lobular features: integrating morphology and E-cadherin immunohistochemistry patterns
Comprehensive characterization of invasive mammary carcinoma with lobular features: integrating morphology and E-cadherin immunohistochemistry patterns
Breast cancer treatment prioritizes molecular subtypes over histologic types. However, considering the unique biological b...
Hub metastatic gene signature and risk score of breast cancer patients with small tumor sizes using WGCNA
Hub metastatic gene signature and risk score of breast cancer patients with small tumor sizes using WGCNA
Breast cancer (BC) is the most common cancer in women and accounts for approximately 15% of all cancer deaths among women ...
Applying whole-genome and whole-exome sequencing in breast cancer: a review of the landscape
Applying whole-genome and whole-exome sequencing in breast cancer: a review of the landscape
Whole-genome sequencing (WGS) and whole-exome sequencing (WES) are crucial within the context of breast cancer (BC) resear...
Capivasertib and fulvestrant for patients with HR-positive/HER2-negative advanced breast cancer: analysis of the subgroup of patients from Japan in the phase 3 CAPItello-291 trial
Capivasertib and fulvestrant for patients with HR-positive/HER2-negative advanced breast cancer: analysis of the subgroup of patients from Japan in the phase 3 CAPItello-291 trial
In CAPItello-291, capivasertib–fulvestrant significantly improved progression-free survival (PFS) versus placeboR...
Mirror therapy for patients with breast cancer: A systematic review and meta-analysis
Mirror therapy for patients with breast cancer: A systematic review and meta-analysis
Pain and dysfunction of the shoulder and arm are prevalent among patients with breast cancer. This review aimed to evaluat...
Prediction model for individualized precision surgery in breast cancer patients with complete response on MRI and residual calcifications on mammography after neoadjuvant chemotherapy
Prediction model for individualized precision surgery in breast cancer patients with complete response on MRI and residual calcifications on mammography after neoadjuvant chemotherapy
Identifying whether there is residual carcinoma in remaining suspicious calcifications after neoadjuvant chemotherapy (NAC...
A genome-wide CRISPR/Cas9 knockout screen identifies SEMA3F gene for resistance to cyclin-dependent kinase 4 and 6 inhibitors in breast cancer
A genome-wide CRISPR/Cas9 knockout screen identifies SEMA3F gene for resistance to cyclin-dependent kinase 4 and 6 inhibitors in breast cancer
Palbociclib is a cell-cycle targeted small molecule agent used as one of the standards of care in combination with endocri...
Integrin β1 in breast cancer: mechanisms of progression and therapy
Integrin β1 in breast cancer: mechanisms of progression and therapy
The therapy for breast cancer (BC), to date, still needs improvement. Apart from traditional therapy methods, biological t...
Desire for pregnancy and fertility preservation in young patients with breast cancer
Desire for pregnancy and fertility preservation in young patients with breast cancer
Data on the desire for pregnancy and the status of fertility preservation (FP) in patients with breast cancer remain uncle...
Breast cancer drugs: FDA approval, development time, efficacy, clinical benefits, innovation, trials, endpoints, quality of life, value, and price
Breast cancer drugs: FDA approval, development time, efficacy, clinical benefits, innovation, trials, endpoints, quality of life, value, and price
This study analyzes the development, benefits, trial evidence, and price of new breast cancer drugs with US Food ...
Utility of a breast biopsy clip and a point marker system in tailored axillary surgery for patients with breast cancer after neoadjuvant chemotherapy
Utility of a breast biopsy clip and a point marker system in tailored axillary surgery for patients with breast cancer after neoadjuvant chemotherapy
Tailored axillary surgery (TAS) is a new approach for selective removal of metastatic lymph nodes. This study evaluated th...
21-gene recurrence score predictive of the benefit of postoperative radiotherapy after breast-conserving surgery for elderly patients with T1N0 and luminal breast cancer
21-gene recurrence score predictive of the benefit of postoperative radiotherapy after breast-conserving surgery for elderly patients with T1N0 and luminal breast cancer
To assess the predictive value of the 21-gene recurrence score (RS) on the survival outcomes of postoperative radiotherapy...
Non-irradiated area of intraoperative radiotherapy with electron technique: outcomes and pattern of failure in early-stage breast cancer from a single-center, registry study
Non-irradiated area of intraoperative radiotherapy with electron technique: outcomes and pattern of failure in early-stage breast cancer from a single-center, registry study
Intraoperative radiotherapy (IORT) with electrons has revealed to have higher rates of ipsilateral breast tumor recurrence...
Clinicopathological and prognostic features of HER2-null and HER2-low advanced breast cancer treated with eribulin or capecitabine
Clinicopathological and prognostic features of HER2-null and HER2-low advanced breast cancer treated with eribulin or capecitabine
HER2-low populations constitute a heterogeneous group, and the cytotoxic anticancer agent efficacy based on HER2 status re...
Increasing survivors of anthracycline-related cardiomyopathy with breast cancer in trastuzumab era: thirty-one-year trends in a Japanese Community
Increasing survivors of anthracycline-related cardiomyopathy with breast cancer in trastuzumab era: thirty-one-year trends in a Japanese Community
Trastuzumab has improved breast cancer (BC) prognosis and reduced anthracycline use. However, the characteristic changes o...
Targeted therapies in HER2-positive breast cancer with receptor-redirected Arazyme-linker-Herceptin as a novel fusion protein
Targeted therapies in HER2-positive breast cancer with receptor-redirected Arazyme-linker-Herceptin as a novel fusion protein
Targeted treatment of different types of cancers through highly expressed cancer cell surface receptors by fusion proteins...
Trastuzumab deruxtecan for the treatment of patients with HER2-positive breast cancer with brain and/or leptomeningeal metastases: an updated overall survival analysis using data from a multicenter retrospective study (ROSET-BM)
Trastuzumab deruxtecan for the treatment of patients with HER2-positive breast cancer with brain and/or leptomeningeal metastases: an updated overall survival analysis using data from a multicenter retrospective study (ROSET-BM)
We provide updated results (median follow-up duration: 20.4 months) of a retrospective study on the effectiveness of trast...
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