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‘Living’ anionic polymerization through reversible activation of C–H bonds with a base catalyst
‘Living’ anionic polymerization through reversible activation of C–H bonds with a base catalyst
Living anionic polymerization is generally carried out using a metal-based initiator under stringent, and ideally water-fr...
Emerging chiral two-dimensional materials
Emerging chiral two-dimensional materials
Research into 2D materials has been growing with impressive speed since the discovery of graphene. Such layered materials ...
Digital skills in chemical education
The role of computers in the chemical sciences is changing. Previously the domain of the theoretical or computational chem...
Expanding the diversity of lithium electrolytes
Expanding the diversity of lithium electrolytes
Improving battery performance requires the careful design of electrolytes. Now, high-performing lithium battery electrolyt...
Generating synthetic gap junctions using supramolecular amphiphilic giant nanotubes
Generating synthetic gap junctions using supramolecular amphiphilic giant nanotubes
The construction of synthetic cells holds great importance for exploring complex biological systems and could potentially ...
Synthetic model interfaces for the study of intermolecular charge-transfer states
Synthetic model interfaces for the study of intermolecular charge-transfer states
The synthesis of model heterojunction interfaces allows for the study of interfacial photoinduced charge-transfer states a...
Synthesis of model heterojunction interfaces reveals molecular-configuration-dependent photoinduced charge transfer
Synthesis of model heterojunction interfaces reveals molecular-configuration-dependent photoinduced charge transfer
Control of the molecular configuration at the interface of an organic heterojunction is key to the development of efficien...
Sulfone cross-coupling outcompetes proton transfer
Sulfone cross-coupling outcompetes proton transfer
The development of enantiospecific sulfone reactions has been hindered by the inherent acidity of sulfones, which result i...
Machine learning trims the peptide drug design process to a sweet spot
Machine learning trims the peptide drug design process to a sweet spot
Drugs that target peptide hormone receptors are of great interest in the treatment of type 2 diabetes. In spite of limited...
Dynamic structural twist in metal–organic frameworks enhances solar overall water splitting
Dynamic structural twist in metal–organic frameworks enhances solar overall water splitting
Photocatalytic overall water splitting holds great promise for solar-to-hydrogen conversion. Maintaining charge separation...
Author Correction: Repurposing a plant peptide cyclase for targeted lysine acylation
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells
Covalent chemistry is a versatile approach for expanding the ligandability of the human proteome. Activity-based protein p...
A dynamic metal–organic framework photocatalyst
A dynamic metal–organic framework photocatalyst
Photocatalytic overall water splitting (OWS) is highly desirable for hydrogen production but challenging owing to rapid ch...
Dynamic-to-static switch of hydrogen bonds induces a metal–insulator transition in an organic–inorganic superlattice
Dynamic-to-static switch of hydrogen bonds induces a metal–insulator transition in an organic–inorganic superlattice
Hydrogen bonds profoundly influence the fundamental chemical, physical and biological properties of molecules and material...
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution
Selenium is an essential micronutrient, but its presence in biology has been limited to protein and nucleic acid biopolyme...
Triplet carbenes with transition-metal substituents
Triplet carbenes with transition-metal substituents
The extraordinary advances in carbene (R1–C–R2) chemistry have been fuelled by strategies to stabilize the ele...
Enantiospecific cross-coupling of cyclic alkyl sulfones
Enantiospecific cross-coupling of cyclic alkyl sulfones
Methods to form carbon–carbon bonds efficiently and with control of stereochemistry are critical for the constructio...
Get to Know NO
Get to Know NO
Nitric oxide is at the heart of myriad environmental and biological processes. Pokhraj Ghosh and Timothy Warren explore th...
How to search for Europan life
How to search for Europan life
In his previous Thesis, Bruce Gibb introduced us to the chemistry of Jupiter’s moons. Now, he takes us on a tour of ...
Flash-within-flash synthesis of gram-scale solid-state materials
Flash-within-flash synthesis of gram-scale solid-state materials
Sustainable manufacturing that prioritizes energy efficiency, minimal water use, scalability and the ability to generate d...
Using dimethylsulfonium to identify readers of methylation
Using dimethylsulfonium to identify readers of methylation
Decoding a post-translational modification requires the identification of its ‘reader’ proteins. Now a method ...
Single-electron transfer between sulfonium and tryptophan enables site-selective photo crosslinking of methyllysine reader proteins
Single-electron transfer between sulfonium and tryptophan enables site-selective photo crosslinking of methyllysine reader proteins
The identification of readers, an important class of proteins that recognize modified residues at specific sites, is essen...
A template for artificial life
A template for artificial life
Selection rules play an important role in Darwinian evolution. Now, it has been shown that selective templation enables th...
Phosphorus-mediated hydrogenation catalysis
Phosphorus-mediated hydrogenation catalysis
Hydrogenation catalysis is commonly associated with (noble) transition metals that undergo oxidative addition of H2 and su...
Light strikes gold to purify water
Light strikes gold to purify water
Hydroxyl radicals (·OH) are important reactive oxygen species in environmental chemistry. The most efficient way to g...
Direct nanoscopic imaging of the hydrated nanoparticle–ligand interface
Direct nanoscopic imaging of the hydrated nanoparticle–ligand interface
The ligand–nanoparticle interface helps to control nanoparticle synthesis and functional properties, but determining...
Magnetic fields reveal signatures of triplet-pair multi-exciton photoluminescence in singlet fission
Magnetic fields reveal signatures of triplet-pair multi-exciton photoluminescence in singlet fission
The photophysical processes of singlet fission and triplet fusion have numerous emerging applications. They involve the se...
Heterotrimeric collagen helix with high specificity of assembly results in a rapid rate of folding
Heterotrimeric collagen helix with high specificity of assembly results in a rapid rate of folding
The most abundant natural collagens form heterotrimeric triple helices. Synthetic mimics of collagen heterotrimers have be...