SCI时时刷

search
Preeclampsia as a possible risk factor for memory impairment, anxiety- and depressive-like behavior in offspring
Preeclampsia as a possible risk factor for memory impairment, anxiety- and depressive-like behavior in offspring
Preeclampsia is a condition that can affect the health in offspring at adult life. The effect on several systems has been ...
Preconception opioids interact with mouse strain to alter morphine withdrawal in the next generation
Preconception opioids interact with mouse strain to alter morphine withdrawal in the next generation
Transgenerational effects of preconception morphine exposure in female rats have been reported which suggest that epigenet...
The effects of pramipexole on motivational vigour during a saccade task: a placebo-controlled study in healthy adults
The effects of pramipexole on motivational vigour during a saccade task: a placebo-controlled study in healthy adults
Motivation allows us to energise actions when we expect reward and is reduced in depression. This effect, termed motivatio...
Noribogaine acute administration in rats promotes wakefulness and suppresses REM sleep
Noribogaine acute administration in rats promotes wakefulness and suppresses REM sleep
Ibogaine is a potent atypical psychedelic that has gained considerable attention due to its antiaddictive and antidepressa...
Supraphysiological testosterone levels from anabolic steroid use and reduced sensitivity to negative facial expressions in men
Supraphysiological testosterone levels from anabolic steroid use and reduced sensitivity to negative facial expressions in men
Anabolic-androgenic steroids (AAS) are used to improve physical performance and appearance, but have been associated with ...
Operant social self-administration in male CD1 mice
Operant social self-administration in male CD1 mice
We recently introduced a model of operant social reward in which female CD1 mice lever press for access to affiliative soc...
Knowledge by omission: the significance of omissions in the 5-choice serial reaction time task
Knowledge by omission: the significance of omissions in the 5-choice serial reaction time task
The 5-choice serial reaction time task (5-CSRTT) is commonly used to assess attention in rodents. Manipulation of this tas...
Changes in distinct brain systems identified with fMRI during smoking cessation treatment with varenicline: a review
Changes in distinct brain systems identified with fMRI during smoking cessation treatment with varenicline: a review
Varenicline is considered one of the most effective treatment options for smoking cessation. Nonetheless, it is only modes...
Neurexin1α knockout in rats causes aberrant social behaviour: relevance for autism and schizophrenia
Neurexin1α knockout in rats causes aberrant social behaviour: relevance for autism and schizophrenia
Genetic and environmental factors cause neuropsychiatric disorders through complex interactions that are far from understo...
Repeated Δ-9-Tetrahydrocannabinol administration dose dependently increases stablished schedule-induced drinking
Repeated Δ-9-Tetrahydrocannabinol administration dose dependently increases stablished schedule-induced drinking
Schedule-induced drinking (SID) reproduces an excessive and repetitive behavioural pattern that has led to propose this pr...
Gut microbiota connects the brain and the heart: potential mechanisms and clinical implications
Gut microbiota connects the brain and the heart: potential mechanisms and clinical implications
Nowadays, high morbidity and mortality of cardiovascular diseases (CVDs) and high comorbidity rate of neuropsychiatric dis...
Effects of estrogen on spatial navigation and memory
Effects of estrogen on spatial navigation and memory
Animal studies suggest that the so-called “female” hormone estrogen enhances spatial navigation and memory. Th...
CaMKIIa+ neurons in the bed nucleus of the stria terminalis modulate pace of natural reward seeking depending on internal state
CaMKIIa+ neurons in the bed nucleus of the stria terminalis modulate pace of natural reward seeking depending on internal state
This study aims to investigate the underlying neurobiological mechanisms that regulate natural reward seeking behaviors, s...
Dorsal hippocampal astrocytes mediate the development of heroin withdrawal-enhanced fear learning
Dorsal hippocampal astrocytes mediate the development of heroin withdrawal-enhanced fear learning
There is a significant co-occurrence of opioid use disorder (OUD) and post-traumatic stress disorder (PTSD) in clinical po...
Synergistic antidepressant-like effect of citicoline and CB 1 agonist in male mice
Synergistic antidepressant-like effect of citicoline and CB 1 agonist in male mice
The endocannabinoid system plays a key role in the control of many emotional-correlated reactions such as stress, depresse...
Attenuated incubation of ethanol-induced conditioned taste aversion in a model of dependence
Attenuated incubation of ethanol-induced conditioned taste aversion in a model of dependence
Preclinical studies report attenuated ethanol-induced conditioned taste aversion (CTA) following chronic ethanol exposure,...
Effects of arginine vasopressin on human anxiety and associations with sex, dose, and V1a-receptor genotype
Effects of arginine vasopressin on human anxiety and associations with sex, dose, and V1a-receptor genotype
Arginine vasopressin (AVP) has dose- and sex-specific effects on social behavior, and variation in social responses is rel...
The impact of doxycycline on human contextual fear memory
The impact of doxycycline on human contextual fear memory
 Previous work identified an attenuating effect of the matrix metalloproteinase (MMP) inhibitor doxycycline on fe...
Individual differences in GHB consumption in a new voluntary GHB self-administration model in outbred rats
Individual differences in GHB consumption in a new voluntary GHB self-administration model in outbred rats
The use of the recreational drug gamma-hydroxybutyric acid (GHB) has increased over the past decade, concomitantly leading...
Intermittent nicotine access is as effective as continuous access in promoting nicotine seeking and taking in rats
Intermittent nicotine access is as effective as continuous access in promoting nicotine seeking and taking in rats
Nicotine is a principal psychoactive agent in tobacco, contributing to tobacco’s addictive potential. Preclinical st...
Subthalamic high-frequency deep brain stimulation reduces addiction-like alcohol use and the possible negative influence of a peer presence
Subthalamic high-frequency deep brain stimulation reduces addiction-like alcohol use and the possible negative influence of a peer presence
The immediate social context significantly influences alcohol consumption in humans. Recent studies have revealed that pee...
Corydaline alleviates Parkinson’s disease by regulating autophagy and GSK-3β phosphorylation
Corydaline alleviates Parkinson’s disease by regulating autophagy and GSK-3β phosphorylation
Jitai tablet, a traditional Chinese medicine, has a neuroprotective effect on 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyrid...
Serum indoleamine 2, 3-dioxygenase and tryptophan-2, 3-dioxygenase: potential biomarkers for the diagnosis of major depressive disorder
Serum indoleamine 2, 3-dioxygenase and tryptophan-2, 3-dioxygenase: potential biomarkers for the diagnosis of major depressive disorder
The objective of this study was to observe the changes in the levels of indoleamine 2, 3-dioxygenase (IDO) and tryptophan-...