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The Saliva and Muscle Study (SaMu): Rationale and Protocol for Associations between Salivary Microbiome and Accelerated Muscle Ageing
The Saliva and Muscle Study (SaMu): Rationale and Protocol for Associations between Salivary Microbiome and Accelerated Muscle Ageing
The gut microbiome is recognized as a pivotal factor in the pathophysiology of sarcopenia—a condition marked by the ...
Exploring the Role of Antibiotics in Hospice Care
Exploring the Role of Antibiotics in Hospice Care
The decision regarding the use of antibiotics in hospice care, whether to initiate, defer, or discontinue therapy, present...
Polyphenol Supplementation and Sarcopenia: A Systematic Review and Meta-Analysis of Clinical Trials
Polyphenol Supplementation and Sarcopenia: A Systematic Review and Meta-Analysis of Clinical Trials
Experimental evidence suggests that polyphenols, a large group of phytochemicals found in fruits and vegetables, may prese...
Application of a Social Vulnerability Index and Its Associations with Physical Frailty and Disability in a Cross-sectional Study of Older Kenyan Women Living with and without HIV
Application of a Social Vulnerability Index and Its Associations with Physical Frailty and Disability in a Cross-sectional Study of Older Kenyan Women Living with and without HIV
Social vulnerability reflects deficits in social resources that may disproportionally impact older women with HIV (WWH) in...
The Relationship between Leisure Time Physical Activity and Cognitive Function in Older Americans
The Relationship between Leisure Time Physical Activity and Cognitive Function in Older Americans
This study aims to investigate the correlation between leisure-time physical activity (LTPA) and cognitive function in old...
Muscle Strength Matters Most for Risk of Falling Apart from Body Mass Index in Older Adults: A Mediated-Moderation Analysis
Muscle Strength Matters Most for Risk of Falling Apart from Body Mass Index in Older Adults: A Mediated-Moderation Analysis
The primary objective of this study was to analyze the moderating effect of body mass index (BMI) on the association betwe...
Fecal Microbiota Transplantation Modulates Gut Microbiome Composition and Glial Signaling in Brain and Colon of Rats with Neuropathic Pain: Evidence for Microbiota-Gut-Brain Axis
Fecal Microbiota Transplantation Modulates Gut Microbiome Composition and Glial Signaling in Brain and Colon of Rats with Neuropathic Pain: Evidence for Microbiota-Gut-Brain Axis
Despite evidence linking the gut microbiome to neuropathic pain (NP), it is not known if altering gut microbiota can allev...
Evaluation of Handgrip Strength Asymmetry to Assess Sarcopenia in Older Patients with Chronic Low Back Pain: A Retrospective Cross-Sectional Study
Evaluation of Handgrip Strength Asymmetry to Assess Sarcopenia in Older Patients with Chronic Low Back Pain: A Retrospective Cross-Sectional Study
Handgrip strength (HGS) is a crucial measurement for diagnosing sarcopenia, and HGS asymmetry indicates functional impairm...
Most Hospital-Acquired Complications among Older Adults Are Associated with Frailty: The South-Western Sydney Frailty and Hospital-Acquired Complications Study
Most Hospital-Acquired Complications among Older Adults Are Associated with Frailty: The South-Western Sydney Frailty and Hospital-Acquired Complications Study
People live longer, and frailty has become an important problem in the acute hospital setting. Increasingly the associatio...
Blood Pressure Variability and Frailty in End-Stage Kidney Disease
Blood Pressure Variability and Frailty in End-Stage Kidney Disease
High blood pressure variability (BPV) is a predictor of cardiovascular events and all-cause mortality in people with end-s...
Admission of Older Patients to Geriatric Inpatient Care from the Emergency Department Compared with Admission through Acute Medical Unit: Cost and Length of Stay Outcomes
Admission of Older Patients to Geriatric Inpatient Care from the Emergency Department Compared with Admission through Acute Medical Unit: Cost and Length of Stay Outcomes
To investigate whether direct admission to geriatric inpatient care from the emergency department (EMD) was associated wit...
Utilisation and Outcome of Cranial CT Imaging in Older Adults Attending ED Following a Fall
Utilisation and Outcome of Cranial CT Imaging in Older Adults Attending ED Following a Fall
Healthcare demand from falls in older adults is increasing, but guidance from the literature is lacking on the value of ne...
Self-Reported Fatigue and Its Cross-Sectional Associations with Physical Function throughout Adulthood: The INSPIRE-T Cohort
Self-Reported Fatigue and Its Cross-Sectional Associations with Physical Function throughout Adulthood: The INSPIRE-T Cohort
Fatigue negatively impacts health outcomes but its association with physical function across the adulthood remains unclear...
Does a Poor Preoperative Nutritional Status Impact outcomes of Heart Valve Surgery?
Does a Poor Preoperative Nutritional Status Impact outcomes of Heart Valve Surgery?
Malnutrition has been variously associated with poor postoperative outcomes. Of note, 10–25 % of cardiac surgery pat...
The Relationship of Frailty with Psychopathology, Childhood Traumas and Insecure Attachment in Young Adults: A Cross-Sectional Investigation
The Relationship of Frailty with Psychopathology, Childhood Traumas and Insecure Attachment in Young Adults: A Cross-Sectional Investigation
Reciprocal connections exist between mental health and physical health, and conditions of cellular senescence/advanced bio...
Five-Time Sit-To-Stand Lower Limb Muscle Power in Older Women: An Explorative, Descriptive and Comparative Analysis
Five-Time Sit-To-Stand Lower Limb Muscle Power in Older Women: An Explorative, Descriptive and Comparative Analysis
Muscle power assessment entails the use of complex equipment which impacts its clinical applicability. Recently, equations...
Impact of Frailty on Gait Speed Improvements in Home Health after Hospital Discharge: Secondary Analysis of Two Randomized Controlled Trials
Impact of Frailty on Gait Speed Improvements in Home Health after Hospital Discharge: Secondary Analysis of Two Randomized Controlled Trials
More than half of older adults are frail or prefrail in the United States, and hospital-associated deconditioning likely i...
Frailty Trajectories and Its Associated Factors in Japanese Older Adults
Frailty Trajectories and Its Associated Factors in Japanese Older Adults
Associated factors for frailty development according to age group remain unclear. To identify frailty score trajectories a...
Analysis of the Correspondence of the Degree of Fragility with the Way to Exercise the Force of the Hand
Analysis of the Correspondence of the Degree of Fragility with the Way to Exercise the Force of the Hand
Frailty is a geriatric syndrome characterized by increased individual vulnerability with an increase in both dependence an...
Correlation between Muscle Mass and Physical Activity Level in Older Adults at Risk of Falling: The FITNESS Study
Correlation between Muscle Mass and Physical Activity Level in Older Adults at Risk of Falling: The FITNESS Study
The study investigates the correlation between muscle mass and physical activity level measured objectively and subjective...
Comparative Analysis of Gait Speed Measurement Protocols: Static Start Versus Dynamic Start in a Cross-Sectional Study Using Light Detection and Ranging
Comparative Analysis of Gait Speed Measurement Protocols: Static Start Versus Dynamic Start in a Cross-Sectional Study Using Light Detection and Ranging
There is currently no standardized protocol for the measurement of gait speed in older adults, particularly regarding the ...
Impact of Interventions on Sarcopenia from the Perspective of Older Persons: A Systematic Literature Review
Impact of Interventions on Sarcopenia from the Perspective of Older Persons: A Systematic Literature Review
Current interventions targeting sarcopenia are diverse, incorporating a blend of nutritional, exercise, and pharmacologica...
Characterizing Deficit Accumulation Among Gulf War Era Veterans
Characterizing Deficit Accumulation Among Gulf War Era Veterans
Veterans of the first Gulf War (1990–1991) are reaching middle and older adulthood in differing degrees of health an...
Association between Dietary Flavonoid Intake and the Likelihood of Frailty in Middle-Aged and Older Adults: A Population-Based Analysis from the National Health and Nutrition Examination Survey (NHANES)
Association between Dietary Flavonoid Intake and the Likelihood of Frailty in Middle-Aged and Older Adults: A Population-Based Analysis from the National Health and Nutrition Examination Survey (NHANES)
Flavonoids are of particular interest for their antioxidant property and anti-inflammatory, and a therapeutic potential fo...
Home-Based Exercise Programs for the Oldest-Old to Attenuate Physical Frailty: A Scoping Review
Home-Based Exercise Programs for the Oldest-Old to Attenuate Physical Frailty: A Scoping Review
With the significant increase in the number of long-lived elderly people living at home, the development of effective phys...
Circulating Angiogenic and Senescent T Lymphocytes in Ageing and Frailty
Circulating Angiogenic and Senescent T Lymphocytes in Ageing and Frailty
There is a need to identify vascular and geroscience-relevant markers and mediators that can physiologically link ageing t...
Integrated Service Delivery Model in Primary Care to Improve Frailty in Older Malaysians: GeKo Integrated Service Delivery
Integrated Service Delivery Model in Primary Care to Improve Frailty in Older Malaysians: GeKo Integrated Service Delivery
This study aimed to evaluate the implementation stage of Malaysia’s GeKo-Integrated Service Delivery (ISD) model for...
Temporal Muscle Thickness Predicts Mortality and Disability in Older Adults Diagnosed with Mild Dementia
Temporal Muscle Thickness Predicts Mortality and Disability in Older Adults Diagnosed with Mild Dementia
Sarcopenia contributes to increased hospitalizations, cognitive impairment, falls, and all-cause mortality. Current diagno...
Association of Finger Tapping Movements with Frailty Status in older Japanese Adults: A Cross-Sectional Study
Association of Finger Tapping Movements with Frailty Status in older Japanese Adults: A Cross-Sectional Study
Finger tapping impairment and frailty share overlapping pathophysiology and symptoms in older adults, however, the relatio...
The Prevalence of Frailty and Associated Factors, Including Food Security in Community Dwelling Older Adults with Multimorbidity: A Cross-Sectional Analysis from the Longitudinal Aging Study in India
The Prevalence of Frailty and Associated Factors, Including Food Security in Community Dwelling Older Adults with Multimorbidity: A Cross-Sectional Analysis from the Longitudinal Aging Study in India
The global increase in multimorbidity among older adults is a result of ongoing epidemiological and demographic transition...
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