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How does the same ligand activate signaling of different receptors in TNFR superfamily: a computational study
How does the same ligand activate signaling of different receptors in TNFR superfamily: a computational study
TNFα is a highly pleiotropic cytokine inducing inflammatory signaling pathways. It is initially presented on plasma m...
Adoptive Transfer of Activated Immune Cells against Solid Tumors: A Preliminary Study
Available online 27 September 2022, 104616Highlights•Novel cellular therapy against solid tumors.•Preliminary results of s...
Cells, Vol. 11, Pages 3053: Mitochondrion-Mediated Cell Death through Erk1-Alox5 Independent of Caspase-9 Signaling
Cells, Vol. 11, Pages 3053: Mitochondrion-Mediated Cell Death through Erk1-Alox5 Independent of Caspase-9 Signaling
Mitochondrial disruption leads to the release of cytochrome c to activate caspase-9 and the downstream caspase cascade for...
Cells, Vol. 11, Pages 3055: Mast Cell Interaction with Foxp3+ Regulatory T Cells Occur in the Dermis after Initiation of IgE-Mediated Cutaneous Anaphylaxis
Cells, Vol. 11, Pages 3055: Mast Cell Interaction with Foxp3+ Regulatory T Cells Occur in the Dermis after Initiation of IgE-Mediated Cutaneous Anaphylaxis
Mast cells (MCs) are well-known for their role in IgE-mediated cutaneous anaphylactic responses, but their regulatory func...
Cells, Vol. 11, Pages 3057: Elucidating the Anti-Tumorigenic Efficacy of Oltipraz, a Dithiolethione, in Glioblastoma
Cells, Vol. 11, Pages 3057: Elucidating the Anti-Tumorigenic Efficacy of Oltipraz, a Dithiolethione, in Glioblastoma
Glioblastoma multiforme (GBM), the most aggressive primary brain tumor, displays a highly infiltrative growth pattern and ...
Cells, Vol. 11, Pages 3060: Silencing the Adipocytokine NOV: A Novel Approach to Reversing Oxidative Stress-Induced Cardiometabolic Dysfunction
Cells, Vol. 11, Pages 3060: Silencing the Adipocytokine NOV: A Novel Approach to Reversing Oxidative Stress-Induced Cardiometabolic Dysfunction
Objective: NOV/CCN3 is an adipocytokine recently linked to obesity, insulin resistance, and cardiometabolic dysfunction. N...
Cells, Vol. 11, Pages 3068: Pancreatic Ductal Adenocarcinoma: Molecular Pathology and Predictive Biomarkers
Cells, Vol. 11, Pages 3068: Pancreatic Ductal Adenocarcinoma: Molecular Pathology and Predictive Biomarkers
Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis due to the lack of methods or biomarkers for early...
Cells, Vol. 11, Pages 3056: Magnetoreceptory Function of European Robin Retina: Electrophysiological and Morphological Non-Homogeneity
Cells, Vol. 11, Pages 3056: Magnetoreceptory Function of European Robin Retina: Electrophysiological and Morphological Non-Homogeneity
The avian magnetic compass allows orientation during migration and is shown to function properly under short-wavelength bu...
Cells, Vol. 11, Pages 3065: Hyaluronic Acid-Coated Bovine Milk Exosomes for Achieving Tumor-Specific Intracellular Delivery of miRNA-204
Cells, Vol. 11, Pages 3065: Hyaluronic Acid-Coated Bovine Milk Exosomes for Achieving Tumor-Specific Intracellular Delivery of miRNA-204
Cell type-specific drug delivery is a straightforward strategy to achieve targeted cancer therapy and reduce side effects....
Cells, Vol. 11, Pages 3054: Photosynthesis in Response to Different Salinities and Immersions of Two Native Rhizophoraceae Mangroves
Cells, Vol. 11, Pages 3054: Photosynthesis in Response to Different Salinities and Immersions of Two Native Rhizophoraceae Mangroves
Mangrove ecosystems are vulnerable to rising sea levels as the plants are exposed to high salinity and tidal submergence. ...
Cells, Vol. 11, Pages 3063: Restored Fyn Levels in Huntington’s Disease Contributes to Enhanced Synaptic GluN2B-Composed NMDA Receptors and CREB Activity
Cells, Vol. 11, Pages 3063: Restored Fyn Levels in Huntington’s Disease Contributes to Enhanced Synaptic GluN2B-Composed NMDA Receptors and CREB Activity
N-methyl-D-aspartate receptors (NMDARs) are important postsynaptic receptors that contribute to normal synaptic function a...
Cells, Vol. 11, Pages 3062: Surgical Menopause Impairs Retinal Conductivity and Worsens Prognosis in an Acute Model of Rat Optic Neuropathy
Cells, Vol. 11, Pages 3062: Surgical Menopause Impairs Retinal Conductivity and Worsens Prognosis in an Acute Model of Rat Optic Neuropathy
Deficiency of estradiol during the menopausal period is an important risk factor for neurodegenerative diseases, including...
The miR-103a-3p/TGFBR3 axis regulates TGF-β-induced orbital fibroblast activation and fibrosis in thyroid-eye disease
Molecular pathways that contribute to orbital fibroblast activation during thyroid-eye disease (TED) may promote TED progr...
Editorial overview: Protein–carbohydrate complexes and glycosylation
Joseph Zaia's research group focusses on analytical biochemistry of glycoproteins and proteoglycans. They have developed m...
Studying membrane modulation mechanisms by electron cryo-tomography
Volume 77, December 2022, 102464Highlights•CryoET images proteins associated with membranes in vitro and in situ.•CryoET u...
Miniature CRISPR-Cas12 endonucleases – Programmed DNA targeting in a smaller package
Volume 77, December 2022, 102466AbstractCRISPR-associated (Cas) endonucleases specifically target and cleave RNA or DNA ba...
New insights into DNA polymerase mechanisms provided by time-lapse crystallography
Volume 77, December 2022, 102465AbstractDNA polymerases play central roles in DNA replication and repair by catalyzing tem...
Markov field models: Scaling molecular kinetics approaches to large molecular machines
Volume 77, December 2022, 102458AbstractWith recent advances in structural biology, including experimental techniques and ...
Mammalian organ regeneration in spiny mice
Mammalian organ regeneration in spiny mice
Fibrosis-driven solid organ failure is a major world-wide health burden with few therapeutic options. Spiny mice (genus: A...
Retraction Note: Upregulated MiR-9-5p Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis via Inhibition of NF-κB p50
Retraction Note: Upregulated MiR-9-5p Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis via Inhibition of NF-κB p50
The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding the western blot data in...
Disengaging the COVID-19 Clutch as a Discerning Eye Over the Inflammatory Circuit During SARS-CoV-2 Infection
Disengaging the COVID-19 Clutch as a Discerning Eye Over the Inflammatory Circuit During SARS-CoV-2 Infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the cytokine release syndrome (CRS) and leads to multi...
Ti Ions Induce IL-1β Release by Activation of the NLRP3 Inflammasome in a Human Macrophage Cell Line
Ti Ions Induce IL-1β Release by Activation of the NLRP3 Inflammasome in a Human Macrophage Cell Line
The aim of the present study was to investigate whether titanium (Ti)-induced release of interleukin (IL)-1β acts thr...