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The effect of TLR3 priming conditions on MSC immunosuppressive properties
The effect of TLR3 priming conditions on MSC immunosuppressive properties
Mesenchymal stromal cells (MSCs) have regenerative and immunomodulatory properties, making them suitable for cell therapy....
Induced pluripotent stem cells modulate the Wnt pathway in the bleomycin-induced model of idiopathic pulmonary fibrosis
Induced pluripotent stem cells modulate the Wnt pathway in the bleomycin-induced model of idiopathic pulmonary fibrosis
The Wnt signaling pathway has been implicated in the pathogenesis of fibrotic disorders and malignancies. Hence, we aimed ...
Deciphering the role of extrachromosomal circular DNA in adipose stem cells from old and young donors
Deciphering the role of extrachromosomal circular DNA in adipose stem cells from old and young donors
The functional impairment of adipose stem cells (ASCs) during aging limits their clinical transformation. Studies have sho...
Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells
Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells
Epithelial–mesenchymal transition (EMT) is a cell remodeling process in which epithelial cells undergo a reversible ...
Adipose-derived mesenchymal stem cells cultured in serum-free medium attenuate acute contrast-induced nephropathy by exerting anti-apoptotic effects
Adipose-derived mesenchymal stem cells cultured in serum-free medium attenuate acute contrast-induced nephropathy by exerting anti-apoptotic effects
Contrast-induced nephropathy (CIN) is a major clinical problem associated with acute kidney injury during hospitalization....
Correction: Mesenchymal stem cell-secreted prostaglandin E2 ameliorates acute liver failure via attenuation of cell death and regulation of macrophage polarization
Correction: Mesenchymal stem cell-secreted prostaglandin E2 ameliorates acute liver failure via attenuation of cell death and regulation of macrophage polarization
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases
Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases
Inherited retinal diseases (IRDs) can induce severe sight-threatening retinal degeneration and impose a considerable econo...
Disclosing the molecular profile of the human amniotic mesenchymal stromal cell secretome by filter-aided sample preparation proteomic characterization
Disclosing the molecular profile of the human amniotic mesenchymal stromal cell secretome by filter-aided sample preparation proteomic characterization
The secretome of mesenchymal stromal cells isolated from the amniotic membrane (hAMSCs) has been extensively studied for i...
HIF-1α promotes kidney organoid vascularization and applications in disease modeling
HIF-1α promotes kidney organoid vascularization and applications in disease modeling
Kidney organoids derived from human pluripotent stem cells (HiPSCs) hold huge applications for drug screening, disease mod...
The influence of inflammation on the characteristics of adipose-derived mesenchymal stem cells (ADMSCs) and tissue repair capability in a hepatic injury mouse model
The influence of inflammation on the characteristics of adipose-derived mesenchymal stem cells (ADMSCs) and tissue repair capability in a hepatic injury mouse model
Mesenchymal stem cells (MSCs) are adult stem cells with self-renewal and multi-directional differentiation potential and p...
Lactate: an alternative pathway for the immunosuppressive properties of mesenchymal stem/stromal cells
Lactate: an alternative pathway for the immunosuppressive properties of mesenchymal stem/stromal cells
The metabolic reprogramming of mesenchymal stem/stromal cells (MSC) favoring glycolysis has recently emerged as a new appr...
The effects of intraovarian injection of autologous menstrual blood-derived mesenchymal stromal cells on pregnancy outcomes in women with poor ovarian response
The effects of intraovarian injection of autologous menstrual blood-derived mesenchymal stromal cells on pregnancy outcomes in women with poor ovarian response
Assisted reproduction faces a significant obstacle in the form of poor ovarian response (POR) to controlled ovarian stimul...
Synergistic effect of chitosan-alginate composite hydrogel enriched with ascorbic acid and alpha-tocopherol under hypoxic conditions on the behavior of mesenchymal stem cells for wound healing
Synergistic effect of chitosan-alginate composite hydrogel enriched with ascorbic acid and alpha-tocopherol under hypoxic conditions on the behavior of mesenchymal stem cells for wound healing
In regenerative medicine, especially skin tissue engineering, the focus is on enhancing the quality of wound healing. Also...
Extracellular vesicles derived from human ESC–MSCs target macrophage and promote anti-inflammation process, angiogenesis, and functional recovery in ACS-induced severe skeletal muscle injury
Extracellular vesicles derived from human ESC–MSCs target macrophage and promote anti-inflammation process, angiogenesis, and functional recovery in ACS-induced severe skeletal muscle injury
Acute compartment syndrome (ACS) is one of the most common complications of musculoskeletal injury, leading to the necrosi...
ADSC secretome constrains NK cell activity by attenuating IL-2-mediated JAK-STAT and AKT signaling pathway via upregulation of CIS and DUSP4
ADSC secretome constrains NK cell activity by attenuating IL-2-mediated JAK-STAT and AKT signaling pathway via upregulation of CIS and DUSP4
Mesenchymal stem cells (MSCs) have immunomodulatory properties and therapeutic effects on autoimmune diseases through thei...
Bright ferritin for long-term MR imaging of human embryonic stem cells
Bright ferritin for long-term MR imaging of human embryonic stem cells
A non-invasive imaging technology that can monitor cell viability, retention, distribution, and interaction with host tiss...
Human mesenchymal stem cells derived from adipose tissue showed a more robust effect than those from the umbilical cord in promoting corneal graft survival by suppressing lymphangiogenesis
Human mesenchymal stem cells derived from adipose tissue showed a more robust effect than those from the umbilical cord in promoting corneal graft survival by suppressing lymphangiogenesis
Mesenchymal stem cells (MSCs) have shown promising potential in allograft survival. However, few reports have focused on c...
The pseudoenzyme ADPRHL1 affects cardiac function by regulating the ROCK pathway
The pseudoenzyme ADPRHL1 affects cardiac function by regulating the ROCK pathway
Pseudoenzymes, catalytically deficient variants of active enzymes, have a wide range of regulatory functions. ADP-ribosylh...
Mechanisms and therapeutic prospects of mesenchymal stem cells-derived exosomes for tendinopathy
Mechanisms and therapeutic prospects of mesenchymal stem cells-derived exosomes for tendinopathy
Tendinopathy is a debilitating and crippling syndrome resulting from the degeneration of tendon tissue, leading to loss of...
Safety and outcomes analysis: transcatheter implantation of autologous angiogenic cell precursors for the treatment of cardiomyopathy
Safety and outcomes analysis: transcatheter implantation of autologous angiogenic cell precursors for the treatment of cardiomyopathy
Stem cell transplantation is an emerging therapy for severe cardiomyopathy, proffering stem cell recruitment, anti-apoptos...
Bioengineered skin constructs based on mesenchymal stromal cells and acellular dermal matrix exposed to inflammatory microenvironment releasing growth factors involved in skin repair
Bioengineered skin constructs based on mesenchymal stromal cells and acellular dermal matrix exposed to inflammatory microenvironment releasing growth factors involved in skin repair
Skin tissue engineering is a rapidly evolving field of research that effectively combines stem cells and biological scaffo...
Correction: NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells
Correction: NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Correction: Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment
Correction: Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Quality management overview for the production of a tissue-engineered human skin substitute in Malaysia
Quality management overview for the production of a tissue-engineered human skin substitute in Malaysia
Treatments for skin injuries have recently advanced tremendously. Such treatments include allogeneic and xenogeneic transp...
Pax7 haploinsufficiency impairs muscle stem cell function in Cre-recombinase mice and underscores the importance of appropriate controls
Pax7 haploinsufficiency impairs muscle stem cell function in Cre-recombinase mice and underscores the importance of appropriate controls
Ever since its introduction as a genetic tool, the Cre-lox system has been widely used for molecular genetic studies in vi...
Novel therapeutic strategies for injured endometrium: intrauterine transplantation of menstrual blood‑derived cells from infertile patients
Novel therapeutic strategies for injured endometrium: intrauterine transplantation of menstrual blood‑derived cells from infertile patients
Menstrual blood-derived cells show regenerative potential as a mesenchymal stem cell and may therefore be a novel stem cel...
Enhancing cord blood stem cell-derived NK cell growth and differentiation through hyperosmosis
Enhancing cord blood stem cell-derived NK cell growth and differentiation through hyperosmosis
Natural killer (NK) cells hold great promise in treating diverse hematopoietic and solid tumors. Despite their availabilit...
Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction
Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction
Direct cardiac reprogramming is currently being investigated for the generation of cells with a true cardiomyocyte (CM) ph...
Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissue
Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissue
Abdominal obesity is appreciated as a major player in insulin resistance and metabolically dysfunctional adipose tissue. I...
Advances in stem cell therapy for peritoneal fibrosis: from mechanisms to therapeutics
Advances in stem cell therapy for peritoneal fibrosis: from mechanisms to therapeutics
Peritoneal fibrosis (PF) is a pathophysiological condition caused by a variety of pathogenic factors. The most important f...
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