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AGEs impair osteogenesis in orthodontic force-induced periodontal ligament stem cells through the KDM6B/Wnt self-reinforcing loop
AGEs impair osteogenesis in orthodontic force-induced periodontal ligament stem cells through the KDM6B/Wnt self-reinforcing loop
Diabetes, occasionally diagnosed in orthodontic patients, can impede orthodontic tooth movement (OTM) by accumulating adva...
Research on the TSPAN6 regulating the secretion of ADSCs-Exos through syntenin-1 and promoting wound healing
Research on the TSPAN6 regulating the secretion of ADSCs-Exos through syntenin-1 and promoting wound healing
Exosomes (Exos) from adipose-derived stem cells (ADSCs) have a high inclusion content and low immunogenicity, which helps ...
Prolonged cultivation enhances the stimulatory activity of hiPSC mesenchymal progenitor-derived conditioned medium
Prolonged cultivation enhances the stimulatory activity of hiPSC mesenchymal progenitor-derived conditioned medium
Human induced pluripotent stem cells represent a scalable source of youthful tissue progenitors and secretomes for regener...
Subcutaneous delivery of mesenchymal stromal cells induces immunoregulatory effects in the lymph node prior to their apoptosis
Subcutaneous delivery of mesenchymal stromal cells induces immunoregulatory effects in the lymph node prior to their apoptosis
Mesenchymal stromal cell (MSC) therapy commonly involves systemic infusion of MSCs, which undergo apoptosis in the lung an...
In vitro electrophysiological drug testing on neuronal networks derived from human induced pluripotent stem cells
In vitro electrophysiological drug testing on neuronal networks derived from human induced pluripotent stem cells
In vitro models for drug testing constitute a valuable and simplified in-vivo-like assay to better comprehend the biologic...
Immortalized mammosphere-derived epithelial cells retain a bioactive secretome with antimicrobial, regenerative, and immunomodulatory properties
Immortalized mammosphere-derived epithelial cells retain a bioactive secretome with antimicrobial, regenerative, and immunomodulatory properties
The secretome of primary bovine mammosphere-derived epithelial cells (MDECs) has been shown to exert antimicrobial, regene...
B2M or CIITA knockdown decreased the alloimmune response of dental pulp stem cells: an in vitro study
B2M or CIITA knockdown decreased the alloimmune response of dental pulp stem cells: an in vitro study
Dental pulp stem cells (DPSCs) have acquired noteworthy attention for their application in treating ischemic diseases and ...
N-CADHERIN+/CD168− subpopulation determines therapeutic variations of UC-MSCs for cardiac repair after myocardial infarction
N-CADHERIN+/CD168− subpopulation determines therapeutic variations of UC-MSCs for cardiac repair after myocardial infarction
The efficiency of mesenchymal stem cells (MSCs) in treating myocardial infarction (MI) remains inconsistent, which limits ...
Cell-based therapies reverse the heart failure-altered right ventricular proteome towards a pre-disease state
Cell-based therapies reverse the heart failure-altered right ventricular proteome towards a pre-disease state
Congenital heart defects can lead to right ventricular (RV) pressure-overload and heart failure. Cell-based therapies, inc...
Transplanted deep-layer cortical neuroblasts integrate into host neural circuits and alleviate motor defects in hypoxic-ischemic encephalopathy injured mice
Transplanted deep-layer cortical neuroblasts integrate into host neural circuits and alleviate motor defects in hypoxic-ischemic encephalopathy injured mice
Hypoxic-ischemic encephalopathy (HIE) is a major cause of neonatal disability and mortality. Although intensive studies an...
Improvement of osteogenic differentiation potential of placenta-derived mesenchymal stem cells by metformin via AMPK pathway activation
Improvement of osteogenic differentiation potential of placenta-derived mesenchymal stem cells by metformin via AMPK pathway activation
Placenta-derived human mesenchymal stem cells (PL-MSCs) have gained a lot of attention in the field of regenerative medici...
Force-triggered density gradient sedimentation and cocktail enzyme digestion treatment for isolation of single dermal papilla cells from follicular unit extraction harvesting human hair follicles
Force-triggered density gradient sedimentation and cocktail enzyme digestion treatment for isolation of single dermal papilla cells from follicular unit extraction harvesting human hair follicles
Hair follicles (HFs) are dynamic structures which are readily accessible within the skin that contain various pools of ste...
Senolysis potentiates endothelial progenitor cell adhesion to and integration into the brain vasculature
Senolysis potentiates endothelial progenitor cell adhesion to and integration into the brain vasculature
One of the most severe consequences of ageing is cognitive decline, which is associated with dysfunction of the brain micr...
Pretreatment with growth differentiation factor 15 augments cardioprotection by mesenchymal stem cells in myocardial infarction by improving their survival
Pretreatment with growth differentiation factor 15 augments cardioprotection by mesenchymal stem cells in myocardial infarction by improving their survival
The clinical application of mesenchymal stem cells (MSCs) in myocardial infarction (MI) is severely hampered by their poor...
Post-symptomatic administration of hMSCs exerts therapeutic effects in SCA2 mice
Post-symptomatic administration of hMSCs exerts therapeutic effects in SCA2 mice
Defects in the ataxin-2 (ATXN-2) protein and CAG trinucleotide repeat expansion in its coding gene, Atxn-2, cause the neur...
Mesenchymal stem cells: a novel therapeutic approach for feline inflammatory bowel disease
Mesenchymal stem cells: a novel therapeutic approach for feline inflammatory bowel disease
Inflammatory bowel disease (IBD) poses a significant and growing global health challenge, affecting both humans and domest...
Management of radiation-induced proctitis using submucosal endoscopic injections of autologous adipose-derived stromal vascular fraction: a case report
Management of radiation-induced proctitis using submucosal endoscopic injections of autologous adipose-derived stromal vascular fraction: a case report
Standard approaches to the treatment of chronic post-radiation proctitis are associated with a high risk of complications ...
Identifying and optimizing critical process parameters for large-scale manufacturing of iPSC derived insulin-producing β-cells
Identifying and optimizing critical process parameters for large-scale manufacturing of iPSC derived insulin-producing β-cells
Type 1 diabetes, an autoimmune disorder leading to the destruction of pancreatic β-cells, requires lifelong insulin t...
Exosomes to exosome-functionalized scaffolds: a novel approach to stimulate bone regeneration
Exosomes to exosome-functionalized scaffolds: a novel approach to stimulate bone regeneration
Bone regeneration is a complex biological process that relies on the orchestrated interplay of various cellular and molecu...
Correction: hPMSCs protects against D-galactose-induced oxidative damage of CD4+ T cells through activating Akt-mediated Nrf2 antioxidant signaling
Correction: hPMSCs protects against D-galactose-induced oxidative damage of CD4+ T cells through activating Akt-mediated Nrf2 antioxidant signaling
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
HES1 revitalizes the functionality of aged adipose-derived stem cells by inhibiting the transcription of STAT1
HES1 revitalizes the functionality of aged adipose-derived stem cells by inhibiting the transcription of STAT1
The effectiveness of adipose-derived stem cells (ADSCs) in therapy diminishes with age. It has been reported that transcri...
Emerging insights into epigenetics and hematopoietic stem cell trafficking in age-related hematological malignancies
Emerging insights into epigenetics and hematopoietic stem cell trafficking in age-related hematological malignancies
Hematopoiesis within the bone marrow (BM) is a complex and tightly regulated process predominantly influenced by immune fa...
Advances in the roles and mechanisms of mesenchymal stem cell derived microRNAs on periodontal tissue regeneration
Advances in the roles and mechanisms of mesenchymal stem cell derived microRNAs on periodontal tissue regeneration
Periodontitis is one of the most prevalent oral diseases leading to tooth loss in adults, and is characterized by the dest...
Mesenchymal stromal cells alleviate APAP-induced liver injury via extracellular vesicle-mediated regulation of the miR-186-5p/CXCL1 axis
Mesenchymal stromal cells alleviate APAP-induced liver injury via extracellular vesicle-mediated regulation of the miR-186-5p/CXCL1 axis
Acetaminophen (APAP) overdose is a significant cause of drug-induced liver injury (DILI). N-acetylcysteine (NAC) is the fi...
Cisplatin-encapsulated TRAIL-engineered exosomes from human chorion-derived MSCs for targeted cervical cancer therapy
Cisplatin-encapsulated TRAIL-engineered exosomes from human chorion-derived MSCs for targeted cervical cancer therapy
Cisplatin (DDP) is an efficacious and widely applied chemotherapeutic drug for cervical cancer patients who are diagnosed ...
The role of mitochondrial transfer in the suppression of CD8+ T cell responses by Mesenchymal stem cells
The role of mitochondrial transfer in the suppression of CD8+ T cell responses by Mesenchymal stem cells
. CD8+ Cytotoxic T lymphocytes play a key role in the pathogenesis of autoimmune diseases and clinical conditions such as ...
Concurrent hypoxia and apoptosis imparts immune programming potential in mesenchymal stem cells: Lesson from acute graft-versus-host-disease model
Concurrent hypoxia and apoptosis imparts immune programming potential in mesenchymal stem cells: Lesson from acute graft-versus-host-disease model
Mesenchymal stem cells (MSCs) have emerged as promising candidates for immune modulation in various diseases that are asso...
Advances in regulating endothelial-mesenchymal transformation through exosomes
Advances in regulating endothelial-mesenchymal transformation through exosomes
Endothelial-mesenchymal transformation (EndoMT) is the process through which endothelial cells transform into mesenchymal ...
Dental stem cell dynamics in periodontal ligament regeneration: from mechanism to application
Dental stem cell dynamics in periodontal ligament regeneration: from mechanism to application
Periodontitis, a globally prevalent chronic inflammatory disease is characterized by the progressive degradation of tooth-...
Advances in retinal pigment epithelial cell transplantation for retinal degenerative diseases
Advances in retinal pigment epithelial cell transplantation for retinal degenerative diseases
Retinal degenerative diseases are a leading cause of vision loss and blindness globally, impacting millions. These disease...
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