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Human umbilical cord mesenchymal stem cell treatment alleviates symptoms in an atopic dermatitis-like mouse model
Human umbilical cord mesenchymal stem cell treatment alleviates symptoms in an atopic dermatitis-like mouse model
Atopic dermatitis (AD) is one of the most common immune and inflammatory skin disorders, leading to insufferable itching a...
MSCs’ conditioned media cytokine and growth factor profiles and their impact on macrophage polarization
MSCs’ conditioned media cytokine and growth factor profiles and their impact on macrophage polarization
There is a growing body of evidence that multipotent mesenchymal stromal cells’ (MSCs’) remarkable therapeutic...
Cell therapy in end-stage liver disease: replace and remodel
Cell therapy in end-stage liver disease: replace and remodel
Liver disease is prevalent worldwide. When it reaches the end stage, mortality rises to 50% or more. Although liver transp...
Potential advantages of genetically modified mesenchymal stem cells in the treatment of acute and chronic liver diseases
Potential advantages of genetically modified mesenchymal stem cells in the treatment of acute and chronic liver diseases
Liver damage caused by toxicity can lead to various severe conditions, such as acute liver failure (ALF), fibrogenesis, an...
Maternal dendritic cells influence fetal allograft response following murine in-utero hematopoietic stem cell transplantation
Maternal dendritic cells influence fetal allograft response following murine in-utero hematopoietic stem cell transplantation
Intrauterine hematopoietic stem cell transplantation (IUT), potentially curative in congenital haematological disease, is ...
Epithelium-derived SCUBE3 promotes polarized odontoblastic differentiation of dental mesenchymal stem cells and pulp regeneration
Epithelium-derived SCUBE3 promotes polarized odontoblastic differentiation of dental mesenchymal stem cells and pulp regeneration
Signal peptide-CUB-EGF domain-containing protein 3 (SCUBE3), a secreted multifunctional glycoprotein whose transcript expr...
Electromagnetic fields regulate calcium-mediated cell fate of stem cells: osteogenesis, chondrogenesis and apoptosis
Electromagnetic fields regulate calcium-mediated cell fate of stem cells: osteogenesis, chondrogenesis and apoptosis
Electromagnetic fields (EMF) are increasing in popularity as a safe and non-invasive therapy. On the one hand, it is widel...
Comparison of the different animal modeling and therapy methods of premature ovarian failure in animal model
Comparison of the different animal modeling and therapy methods of premature ovarian failure in animal model
Incidence of premature ovarian failure (POF) is higher with the increase of the pace of life. The etiology of POF is very ...
Comparison of therapeutic effects of mesenchymal stem cells derived from superficial and deep subcutaneous adipose tissues
Comparison of therapeutic effects of mesenchymal stem cells derived from superficial and deep subcutaneous adipose tissues
Fibrosis is a common histological feature in the process from chronic organ injury to organ failure. Chronic tissue injury...
Optimization strategies of mesenchymal stem cell-based therapy for acute kidney injury
Optimization strategies of mesenchymal stem cell-based therapy for acute kidney injury
Considering the high prevalence and the lack of targeted pharmacological management of acute kidney injury (AKI), the sear...
Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells
Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells
In vertebrates, hematopoietic stem and progenitor cells (HSPCs) emerge from hemogenic endothelium in the floor of the dors...
PDGFBB improved the biological function of menstrual blood-derived stromal cells and the anti-fibrotic properties of exosomes
PDGFBB improved the biological function of menstrual blood-derived stromal cells and the anti-fibrotic properties of exosomes
Intrauterine adhesion (IUA) is a reproductive dysfunction disease characterized by endometrial fibrosis, with limited ther...
In vitro erythrocyte production using human-induced pluripotent stem cells: determining the best hematopoietic stem cell sources
In vitro erythrocyte production using human-induced pluripotent stem cells: determining the best hematopoietic stem cell sources
Blood transfusion is an essential part of medicine. However, many countries have been facing a national blood crisis. To a...
Effects of hormones on intestinal stem cells
Effects of hormones on intestinal stem cells
The maintenance of intestinal renewal and repair mainly depends on intestinal stem cells (ISCs), which can also contribute...
Semi-automated optimized method to isolate CRISPR/Cas9 edited human pluripotent stem cell clones
Semi-automated optimized method to isolate CRISPR/Cas9 edited human pluripotent stem cell clones
CRISPR/Cas9 editing systems are currently used to generate mutations in a particular gene to mimic a genetic disorder in v...
Immunomodulatory amnion-derived mesenchymal stromal cells preserve muscle function in a mouse model of Duchenne muscular dystrophy
Immunomodulatory amnion-derived mesenchymal stromal cells preserve muscle function in a mouse model of Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is an incurable genetic disease characterized by degeneration and necrosis of myofibers,...