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Post-symptomatic administration of hMSCs exerts therapeutic effects in SCA2 mice
Post-symptomatic administration of hMSCs exerts therapeutic effects in SCA2 mice
Defects in the ataxin-2 (ATXN-2) protein and CAG trinucleotide repeat expansion in its coding gene, Atxn-2, cause the neur...
Mesenchymal stem cells: a novel therapeutic approach for feline inflammatory bowel disease
Mesenchymal stem cells: a novel therapeutic approach for feline inflammatory bowel disease
Inflammatory bowel disease (IBD) poses a significant and growing global health challenge, affecting both humans and domest...
Exosomes to exosome-functionalized scaffolds: a novel approach to stimulate bone regeneration
Exosomes to exosome-functionalized scaffolds: a novel approach to stimulate bone regeneration
Bone regeneration is a complex biological process that relies on the orchestrated interplay of various cellular and molecu...
HES1 revitalizes the functionality of aged adipose-derived stem cells by inhibiting the transcription of STAT1
HES1 revitalizes the functionality of aged adipose-derived stem cells by inhibiting the transcription of STAT1
The effectiveness of adipose-derived stem cells (ADSCs) in therapy diminishes with age. It has been reported that transcri...
Emerging insights into epigenetics and hematopoietic stem cell trafficking in age-related hematological malignancies
Emerging insights into epigenetics and hematopoietic stem cell trafficking in age-related hematological malignancies
Hematopoiesis within the bone marrow (BM) is a complex and tightly regulated process predominantly influenced by immune fa...
Advances in the roles and mechanisms of mesenchymal stem cell derived microRNAs on periodontal tissue regeneration
Advances in the roles and mechanisms of mesenchymal stem cell derived microRNAs on periodontal tissue regeneration
Periodontitis is one of the most prevalent oral diseases leading to tooth loss in adults, and is characterized by the dest...
Cisplatin-encapsulated TRAIL-engineered exosomes from human chorion-derived MSCs for targeted cervical cancer therapy
Cisplatin-encapsulated TRAIL-engineered exosomes from human chorion-derived MSCs for targeted cervical cancer therapy
Cisplatin (DDP) is an efficacious and widely applied chemotherapeutic drug for cervical cancer patients who are diagnosed ...
The role of mitochondrial transfer in the suppression of CD8+ T cell responses by Mesenchymal stem cells
The role of mitochondrial transfer in the suppression of CD8+ T cell responses by Mesenchymal stem cells
. CD8+ Cytotoxic T lymphocytes play a key role in the pathogenesis of autoimmune diseases and clinical conditions such as ...
Advances in regulating endothelial-mesenchymal transformation through exosomes
Advances in regulating endothelial-mesenchymal transformation through exosomes
Endothelial-mesenchymal transformation (EndoMT) is the process through which endothelial cells transform into mesenchymal ...
Dental stem cell dynamics in periodontal ligament regeneration: from mechanism to application
Dental stem cell dynamics in periodontal ligament regeneration: from mechanism to application
Periodontitis, a globally prevalent chronic inflammatory disease is characterized by the progressive degradation of tooth-...
Advances in retinal pigment epithelial cell transplantation for retinal degenerative diseases
Advances in retinal pigment epithelial cell transplantation for retinal degenerative diseases
Retinal degenerative diseases are a leading cause of vision loss and blindness globally, impacting millions. These disease...
Promotion of nerve regeneration and motor function recovery in SCI rats using LOCAS-iPSCs-NSCs
Promotion of nerve regeneration and motor function recovery in SCI rats using LOCAS-iPSCs-NSCs
Spinal cord injury (SCI) is a severe traumatic spinal condition with a poor prognosis. In this study, a scaffold called li...
Adipose-derived mesenchymal stem cells inhibit hepatic stellate cells activation to alleviate liver fibrosis via Hippo pathway
Adipose-derived mesenchymal stem cells inhibit hepatic stellate cells activation to alleviate liver fibrosis via Hippo pathway
Liver fibrosis is a common pathological process of chronic liver disease, characterized by excessive deposition of extrace...
Intrauterine adhesions repair with menstrual blood-derived mesenchymal stem cells via CXCL13-CXCR5 signal axis and its mechanism
Intrauterine adhesions repair with menstrual blood-derived mesenchymal stem cells via CXCL13-CXCR5 signal axis and its mechanism
Intrauterine Adhesions (IUA) is a common gynecological disease which is seriously endangers the reproductive function of w...
Current advances in understanding endometrial epithelial cell biology and therapeutic applications for intrauterine adhesion
Current advances in understanding endometrial epithelial cell biology and therapeutic applications for intrauterine adhesion
The human endometrium is a highly regenerative tissue capable of undergoing scarless repair during the menstruation and po...
The role of biophysical cues and their modulated exosomes in dental diseases: from mechanism to therapy
The role of biophysical cues and their modulated exosomes in dental diseases: from mechanism to therapy
Dental diseases such as caries and periodontitis have been common public health problems. Dental disease treatment can be ...
Advancing wound healing by hydrogel-based dressings loaded with cell-conditioned medium: a systematic review
Advancing wound healing by hydrogel-based dressings loaded with cell-conditioned medium: a systematic review
Wound healing represents a complex biological process, critically important in clinical practice due to its direct implica...
Extracellular vesicles as therapeutic tools in regenerative dentistry
Extracellular vesicles as therapeutic tools in regenerative dentistry
Dental and maxillofacial diseases are always accompanied by complicated hard and soft tissue defects, involving bone, teet...
iPSC-derived megakaryocytes and platelets accelerate wound healing and angiogenesis
iPSC-derived megakaryocytes and platelets accelerate wound healing and angiogenesis
Platelet-rich plasma (PRP), which is prepared by concentrating platelets in autologous blood, shows efficacy in chronic sk...
Intracellular osteopontin potentiates the immunosuppressive activity of mesenchymal stromal cells
Intracellular osteopontin potentiates the immunosuppressive activity of mesenchymal stromal cells
Mesenchymal stromal cell (MSC)-based cell therapy is a promising approach for various inflammatory disorders based on thei...
Induced pluripotent stem cell-derived mesenchymal stem cells: whether they can become new stars of cell therapy
Induced pluripotent stem cell-derived mesenchymal stem cells: whether they can become new stars of cell therapy
Stem cell therapy constitutes a pivotal subject in contemporary discourse, with donor stem cells having been employed in r...
Extracellular vesicles from human cardiac stromal cells up-regulate cardiomyocyte protective responses to hypoxia
Extracellular vesicles from human cardiac stromal cells up-regulate cardiomyocyte protective responses to hypoxia
Cell therapy can protect cardiomyocytes from hypoxia, primarily via paracrine secretions, including extracellular vesicles...