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MACF1 overexpression in BMSCs alleviates senile osteoporosis in mice through TCF4/miR-335–5p signaling pathway
Volume 39, March 2023, Pages 177-190Author links open overlay panel, , , , , , , AbstractBackgroundThe decreased osteogeni...
Identification of the miRNAome in human fracture callus and nonunion tissues
Volume 39, March 2023, Pages 113-123Author links open overlay panel, , AbstractBackgroundNonunions remain a challenging po...
Cerebrospinal fluid-derived extracellular vesicles after spinal cord injury promote vascular regeneration via PI3K/AKT signaling pathway
Volume 39, March 2023, Pages 124-134Author links open overlay panel, , , , , , AbstractBackgroundThe cerebrospinal fluid (...
Pharmacological network analysis of the functions and mechanism of kaempferol from Du Zhong in intervertebral disc degeneration (IDD)
BackgroundSenescence and apoptosis of the nucleus pulposus cells (NPCs) are essential components of the intervertebral dis...
Forkhead box O3 attenuates osteoarthritis by suppressing ferroptosis through inactivation of NF-κB/MAPK signaling
Volume 39, March 2023, Pages 147-162Author links open overlay panel, , , , , , , , AbstractBackgroundFerroptosis is a nona...
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration
Volume 39, March 2023, Pages 163-176Author links open overlay panel, , AbstractBackgroundIntervertebral disc degeneration ...
Exosomes from CD133+ human urine-derived stem cells combined adhesive hydrogel facilitate rotator cuff healing by mediating bone marrow mesenchymal stem cells
BackgroundThe inadequate regeneration of natural tissue (mainly fibrocartilage) between tendon and bone during rotator cuf...
2023 January issue Journal of Orthopaedic Translation
Volume 38, January 2023, Pages A1-A3Author links open overlay panelGuozhi Xiao (Associate Editor, Journal of Orthopaedic T...
Advances in experimental models of osteonecrosis of the femoral head
BackgroundOsteonecrosis of the femoral head (ONFH) is a devastating disease affecting young adults, resulting in significa...
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects
BackgroundThe incidence of intervertebral disc degeneration (IVDD) is a common degenerative disease with inflammation, dec...
Mesenchymal stem cells and macrophages and their interactions in tendon-bone healing
Volume 39, March 2023, Pages 63-73Author links open overlay panelAbstractTendon-bone insertion injuries (TBI), such as ant...
The effect of drug holiday on preventing medication-related osteonecrosis of the jaw in osteoporotic rat model
Volume 39, March 2023, Pages 55-62Author links open overlay panelAbstractBackgroundMedication-related osteonecrosis of the...
A static magnetic field enhances the repair of osteoarthritic cartilage by promoting the migration of stem cells and chondrogenesis
Volume 39, March 2023, Pages 43-54Author links open overlay panelAbstractObjectiveTo investigate the therapeutic effects o...
Gallic acid mediates tumor-suppressive effects on osteosarcoma through the H19-Wnt/β-catenin regulatory axis
Volume 39, March 2023, Pages 34-42Author links open overlay panelAbstractBackgroundOsteosarcoma (OS) is the most common pr...
Netrin-1 mediates nerve innervation and angiogenesis leading to discogenic pain
Volume 39, March 2023, Pages 21-33Author links open overlay panelAbstractObjectiveDiscogenic low back pain (LBP) is associ...
Is dexamethasone-induced muscle atrophy an alternative model for naturally aged sarcopenia model?
Volume 39, March 2023, Pages 12-20Author links open overlay panelAbstractBackgroundPrimary sarcopenia is usually known as ...
Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice
Volume 38, January 2023, Pages 241-255Author links open overlay panelAbstractObjectiveKnee osteoarthritis (KOA) is a highl...
Single-cell RNA sequencing reveals resident progenitor and vascularization-associated cell subpopulations in rat annulus fibrosus
Volume 38, January 2023, Pages 256-267Author links open overlay panelAbstractBackgroundOne of the main causes of low back ...
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis
BackgroundOsteoarthritis (OA) is the most common chronic disease. It is characterized by high levels of clinical heterogen...
PINK1-mediated mitophagy contributes to glucocorticoid-induced cathepsin K production in osteocytes
Volume 38, January 2023, Pages 229-240Author links open overlay panelAbstractBackgroundGlucocorticoid (GC) is one of frequ...
Capability of auxetic femoral stems to reduce stress shielding after total hip arthroplasty
Volume 38, January 2023, Pages 220-228Author links open overlay panelAbstractBackgroundStress shielding ​(SS) is considere...
Preclinical model for lumbar interbody fusion in small ruminants: Rationale and guideline
Volume 38, January 2023, Pages 167-174Author links open overlay panelAbstractLumbar interbody fusion (IF) is a common proc...
AMPK activator decelerates osteoarthritis development by inhibition of β-catenin signaling in chondrocytes
Volume 38, January 2023, Pages 158-166Author links open overlay panelAbstractBackgroundOsteoarthritis (OA) is a common deg...
Irisin reduces bone fracture by facilitating osteogenesis and antagonizing TGF-β/Smad signaling in a growing mouse model of osteogenesis imperfecta
Volume 38, January 2023, Pages 175-189Author links open overlay panelAbstractObjectiveOsteogenesis imperfecta (OI) is a co...
Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-κB pathway
BackgroundOsteoarthritis (OA) is a chronic disease that may cause articular cartilage degeneration, and synovial inflammat...
Combination of cobalt, chromium and titanium nanoparticles increases cytotoxicity in vitro and pro-inflammatory cytokines in vivo
Volume 38, January 2023, Pages 203-212Author links open overlay panelAbstractBackgroundThe mixture of different metallic n...
Soluble interleukin 2 receptor is risk for sarcopenia in Men with high fracture risk
Volume 38, January 2023, Pages 213-219Author links open overlay panelAbstractBackground & aimsSarcopenia is an age-rel...
Therapeutic effect of induced pluripotent stem cell -derived extracellular vesicles in an in vitro and in vivo osteoarthritis model
Volume 38, January 2023, Pages 141-155AbstractBackground/ObjectiveOsteoarthritis (OA) is a multifactorial joint disease as...
A template to develop humanized technologies that meet true clinical needs
Volume 38, January 2023, Pages 156-157Navigate LeftPrevious article in issueNext article in issueNavigate RightKeywordsGen...
Bone tissue engineering scaffolds with HUVECs/hBMSCs cocultured on 3D-printed composite bioactive ceramic scaffolds promoted osteogenesis/angiogenesis
Volume 37, November 2022, Pages 152-162AbstractBackground/Objective: Tissue engineering involves scaffolds, cells and grow...
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