SCI时时刷

search
+
Basic research is the foundation and driving force for clinical translation
Basic research is the foundation and driving force for clinical translation
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Knee osteoarthritis pendulum therapy: In vivo evaluation and a randomised, single-blind feasibility clinical trial
Knee osteoarthritis pendulum therapy: In vivo evaluation and a randomised, single-blind feasibility clinical trial
BackgroundExercise is recommended as the first-line management for knee osteoarthritis (KOA); however, it is difficult to ...
Time trends in the burden of low back pain and its associated risk factors in China from 1990 to 2019
Time trends in the burden of low back pain and its associated risk factors in China from 1990 to 2019
BackgroundFrom 1990 to 2019, low back pain (LBP) was the leading cause of years lived with disability (YLDs) in China. How...
Quercetin-3-O-β-D-glucuronide attenuates osteoarthritis by inhibiting cartilage extracellular matrix degradation and inflammation
Quercetin-3-O-β-D-glucuronide attenuates osteoarthritis by inhibiting cartilage extracellular matrix degradation and inflammation
KeywordsExtracellular matrixInflammationNrf2OsteoarthritisQuercetin-3-O-β-D-glucuronideAbbreviationsQ3GAquercetin-3-O-β-D-...
The LANCET robotic system can improve surgical efficiency in total hip arthroplasty: A prospective randomized, multicenter, parallel-controlled clinical trial
The LANCET robotic system can improve surgical efficiency in total hip arthroplasty: A prospective randomized, multicenter, parallel-controlled clinical trial
Volume 45, March 2024, Pages 247-255Author links open overlay panel, , , , , , , , , , , , , , , , , AbstractObjectiveTo e...
RPL35 downregulated by mechanical overloading promotes chondrocyte senescence and osteoarthritis development via Hedgehog-Gli1 signaling
RPL35 downregulated by mechanical overloading promotes chondrocyte senescence and osteoarthritis development via Hedgehog-Gli1 signaling
Volume 45, March 2024, Pages 226-235Author links open overlay panel, , , , , , , , , , , , , AbstractObjectivesTo investig...
Therapeutic potential of a prominent dihydroxyflavanone pinocembrin for osteolytic bone disease: In vitro and in vivo evidence
Therapeutic potential of a prominent dihydroxyflavanone pinocembrin for osteolytic bone disease: In vitro and in vivo evidence
Background/objectiveAs the pivotal cellular mediators of bone resorption and pathological bone remodeling, osteoclasts hav...
IRF1 governs the expression of SMARCC1 via the GCN5-SETD2 axis and actively engages in the advancement of osteoarthritis
IRF1 governs the expression of SMARCC1 via the GCN5-SETD2 axis and actively engages in the advancement of osteoarthritis
BackgroundOsteoarthritis (OA) is a degenerative joint disease characterized by the breakdown of joint cartilage and underl...
Salivary nitrate prevents osteoporosis via regulating bone marrow mesenchymal stem cells proliferation and differentiation
Salivary nitrate prevents osteoporosis via regulating bone marrow mesenchymal stem cells proliferation and differentiation
BackgroundNitrate, a key component of saliva, has been shown widely physiological functions in the human body. But its fun...
Schnurri-3 controls osteogenic fate of Adipoq-lineage progenitors in bone marrow
Schnurri-3 controls osteogenic fate of Adipoq-lineage progenitors in bone marrow
BackgroundRecently, the osteogenic potential of Adiponectin-labeled adipogenic lineage progenitors (Adipoq-lineage progeni...
Cycloastragenol prevents bone loss via inhibiting osteoclast activity in glucocorticoid-induced osteonecrosis of the femoral head: An in vivo study
Cycloastragenol prevents bone loss via inhibiting osteoclast activity in glucocorticoid-induced osteonecrosis of the femoral head: An in vivo study
BackgroundGlucocorticoid-induced osteonecrosis of the femoral head (GIONFH) is a common bone and joint disease. There is c...
The Revolution of exosomes: From biological functions to therapeutic applications in skeletal muscle diseases
The Revolution of exosomes: From biological functions to therapeutic applications in skeletal muscle diseases
Skeletal muscle diseases, a broad category encompassing a myriad of afflictions such as acute muscle injury and muscular d...
Enhanced articular cartilage regeneration using costal chondrocyte-derived scaffold-free tissue engineered constructs with ascorbic acid treatment
Enhanced articular cartilage regeneration using costal chondrocyte-derived scaffold-free tissue engineered constructs with ascorbic acid treatment
KeywordsArticular cartilage regenerationCartilage tissue engineeringCostal chondrocytesOsteochondral defectScaffold-free t...
Engineering a functional ACL reconstruction graft containing a triphasic enthesis-like structure in bone tunnel for the enhancement of graft-to-bone integration
Engineering a functional ACL reconstruction graft containing a triphasic enthesis-like structure in bone tunnel for the enhancement of graft-to-bone integration
BackgroundAnterior cruciate ligament (ACL) rupture is a common sports injury, which causes knee instability and abnormal j...
The potential of sheep in preclinical models for bone infection research – A systematic review
The potential of sheep in preclinical models for bone infection research – A systematic review
BackgroundReliable animal models are critical for preclinical research and should closely mimic the disease. With respect ...
Tibial cortex transverse transport regulates Orai1/STIM1-mediated NO release and improve the migration and proliferation of vessels via increasing osteopontin expression
Tibial cortex transverse transport regulates Orai1/STIM1-mediated NO release and improve the migration and proliferation of vessels via increasing osteopontin expression
BackgroundDiabetic foot is a major complication of diabetes. The bone transverse transport method could be applied in clin...
Radiomics signature of osteoarthritis: Current status and perspective
Radiomics signature of osteoarthritis: Current status and perspective
Volume 45, March 2024, Pages 100-106Author links open overlay panel, , , , , , , AbstractOsteoarthritis (OA) is one of the...
Mechanisms and therapeutic strategies for senescence-associated secretory phenotype in the intervertebral disc degeneration microenvironment
Mechanisms and therapeutic strategies for senescence-associated secretory phenotype in the intervertebral disc degeneration microenvironment
As a permanent state of cell cycle arrest, cellular senescence has become an important factor in aging and age-related dis...
A novel therapy for fracture healing by increasing lymphatic drainage
A novel therapy for fracture healing by increasing lymphatic drainage
BackgroundThe musculoskeletal system contains an extensive network of lymphatic vessels. Decreased lymph flow of the drain...
Pentamidine-loaded gelatin decreases adhesion formation of flexor tendon
Pentamidine-loaded gelatin decreases adhesion formation of flexor tendon
Volume 45, March 2024, Pages 75-87Author links open overlay panel, , , , , , , , , , AbstractBackgroundPrevention of adhes...
Appreciable biosafety, biocompatibility and osteogenic capability of 3D printed nonstoichiometric wollastonite scaffolds favorable for clinical translation
Appreciable biosafety, biocompatibility and osteogenic capability of 3D printed nonstoichiometric wollastonite scaffolds favorable for clinical translation
BackgroundAlveolar bone destruction due to periodontal disease often requires a bone graft substitute to reconstruct the a...
Clinical guideline on the third generation minimally invasive surgery for hallux valgus
Clinical guideline on the third generation minimally invasive surgery for hallux valgus
Minimally invasive surgery for hallux valgus correction, has been attracting great interests in the recent decades, due to...
Implants coating strategies for antibacterial treatment in fracture and defect models: A systematic review of animal studies
Implants coating strategies for antibacterial treatment in fracture and defect models: A systematic review of animal studies
ObjectiveFracture-related infection (FRI) remains a major concern in orthopaedic trauma. Functionalizing implants with ant...
Pip5k1c expression in osteocytes regulates bone remodeling in mice
Pip5k1c expression in osteocytes regulates bone remodeling in mice
Volume 45, March 2024, Pages 36-47Author links open overlay panel, , , , , , , , , , AbstractResearch backgroundThe role o...
Shock wave assisted intracellular delivery of antibiotics against bone infection with Staphylococcus aureus via P2X7 receptors
Shock wave assisted intracellular delivery of antibiotics against bone infection with Staphylococcus aureus via P2X7 receptors
BackgroundTreatment of chronic osteomyelitis (bone infection) remains a clinical challenge; in particular, it requires enh...
Intra-articular injection of platelet lysate-derived extracellular vesicles recovers from knee osteoarthritis in an in vivo rat model
Intra-articular injection of platelet lysate-derived extracellular vesicles recovers from knee osteoarthritis in an in vivo rat model
ObjectiveMSCs and Platelet-Rich Plasma are the main focus in the study of new regenerative treatments aimed to reverse Ost...
Advances in osteoarthritis research: From diagnosis, treatment to mechanism studies
Advances in osteoarthritis research: From diagnosis, treatment to mechanism studies
Available online 6 February 2024Author links open overlay panelZhongyang Lv a b, Ziling Wang c d e, Di Chen c d, Dongquan ...
ChatGPT for scientific writing — The coexistence of opportunities and challenges
ChatGPT for scientific writing — The coexistence of opportunities and challenges
Available online 6 February 2024Author links open overlay panelLiangbin Zhou 1, Alex Chao Wu 2, Péter Hegyi, Chunyi Wen, L...
Inhibition of PI3K/AKT signaling pathway prevents blood-induced heterotopic ossification of the injured tendon
Inhibition of PI3K/AKT signaling pathway prevents blood-induced heterotopic ossification of the injured tendon
ObjectiveIt is a common clinical phenomenon that blood infiltrates into the injured tendon caused by sports injuries, acci...
G protein-coupled receptor 30 activation inhibits ferroptosis and protects chondrocytes against osteoarthritis
G protein-coupled receptor 30 activation inhibits ferroptosis and protects chondrocytes against osteoarthritis
BackgroundOsteoarthritis (OA) is the most common joint disease worldwide, but its cause remains unclear. Oestrogen protect...
阅读更多
format_indent_increase