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ECFC-derived exosomal THBS1 mediates angiogenesis and osteogenesis in distraction osteogenesis via the PI3K/AKT/ERK pathway
Volume 37, November 2022, Pages 12-22AbstractBackgroundDistraction osteogenesis (DO) is a widely used bone regenerative te...
Irisin promotes fracture healing by improving osteogenesis and angiogenesis
Volume 37, November 2022, Pages 37-45AbstractBackgroundOsteogenesis and angiogenesis are important for bone fracture heali...
An injectable pH neutral bioactive glass-based bone cement with suitable bone regeneration ability
BackgroundAs a class of promising bone augmentation materials, bone cements have attracted particular attention. Due to va...
Specific microRNAs are associated with fracture healing phases, patient age and multi-trauma
Volume 37, November 2022, Pages 1-11AbstractBackgroundImmediately after a fracture occurs, a fracture hematoma (fxH) is fo...
Regulation of mitochondrial dynamic equilibrium by physical exercise in sarcopenia: A systematic review
Volume 35, July 2022, Pages 37-52AbstractBackgroundSarcopenia is a hallmark of the ageing process, which is characterized ...
Clinical perspectives for repairing rotator cuff injuries with multi-tissue regenerative approaches
Volume 36, September 2022, Pages 91-108AbstractBackgroundIn the musculoskeletal system, bone, tendon, and muscle form high...
Modulating macrophage polarization for the enhancement of fracture healing, a systematic review
Volume 36, September 2022, Pages 83-90AbstractBackgroundAll fracture repairs start with the innate immune system with the ...
Exosome-based strategy for degenerative disease in orthopedics: Recent progress and perspectives
Volume 36, September 2022, Pages 8-17AbstractBackgroundDegenerative diseases in orthopaedics have become a significant glo...
Biomimicking design of artificial periosteum for promoting bone healing
Volume 36, September 2022, Pages 18-32AbstractBackgroundPeriosteum is a vascularized tissue membrane covering the bone sur...
Treatment of tibial plateau fractures: A comparison of two different operation strategies with medium-term follow up
Volume 36, September 2022, Pages 1-7AbstractBackgroundThe objective of this study was to compare the clinical and radiolog...
Identification and diagnosis of meniscus tear by magnetic resonance imaging using a deep learning model
Volume 34, May 2022, Pages 91-101AbstractObjectiveMeniscus tear is a common problem in sports trauma, and its imaging diag...
Clinical translation of a patient-specific scaffold-guided bone regeneration concept in four cases with large long bone defects
Volume 34, May 2022, Pages 73-84AbstractBackgroundBone defects after trauma, infection, or tumour resection present a chal...
Innovative biomaterials, drugs and technologies for musculoskeletal diseases
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Osteocyte β1 integrin loss causes low bone mass and impairs bone mechanotransduction in mice
Volume 34, May 2022, Pages 60-72AbstractBackgroundThe key focal adhesion protein β1 integrin plays an essential role in ea...
Clinical applications and prospects of 3D printing guide templates in orthopaedics
BackgroundWith increasing requirements for medical effects, and huge differences among individuals, traditional surgical i...
ZnO nanoparticles attenuate polymer-wear-particle induced inflammatory osteolysis by regulating the MEK-ERK-COX-2 axis
Volume 34, May 2022, Pages 1-10AbstractBackground/ObjectivesAdvanced thermoplastic materials, such as polyether-ether-keto...
The emerging translational potential of GDF11 in chronic wound healing
Available online 19 April 2022AbstractChronic skin wounds impose immense suffers and economic burdens. Current research ma...