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Large-scale Expanded Sample Imaging With Tiling Lattice Lightsheet Microscopy
Expansion microscopy (ExM) is a powerful technology to resolve biological structures below the optical diffraction limit. ...
APC/C CDH1 ubiquitinates STAT3 in mitosis
STAT3, a transcription factor is classified as an oncogene (Bromberg et al., 1999). STAT3 undergoes over 80 posttranslatio...
Antigen presenting cells: professionals, amateurs, and spectators in the 'long game' of lung immunity
The lung is frequently and repeatedly exposed to invading pathogens and thus requires constant immunosurveillance. Profess...
Regulation of human ZNF687, a gene associated with Paget´s disease of bone
Mutations in Zinc finger 687 (ZNF687) were associated with Paget’s disease of bone (PDB), a disease characterized by incre...
Influence of tumor cell-derived TGF-β on macrophage phenotype and macrophage-mediated tumor cell invasion
In oral squamous cell carcinoma (OSCC), macrophages are the most abundant immune cell type in the tumor microenvironment (...
Changes in epigenetic information during the occurrence and development of gastric cancer
Gastric cancer is one of the most common malignant tumors of the digestive tract, with a high degree of malignancy and poo...
Role of CXCR3 in fibrotic tissue responses
Development of fibrosis leads to end stage diseases that defy treatments across all organs. This ensues as chronic inflamm...
Caveolin-1 Signaling-Driven Mitochondrial Fission and Cytoskeleton Remodeling Promotes Breast Cancer Migration
Mitochondria are highly dynamic organelles that constantly divide and fuse to maintain their proper structure and function...
The Multifaceted Role of Micronuclei in Tumour Progression: A whole organism perspective.
Within most tumour types, cancerous cells exist in a state of aneuploidy, an incorrect chromosome number or structure. Add...
IGF2BP2 promotes the progression of ovarian endometriosis by regulating m6A-modified MEIS2 and GATA6
Available online 13 September 2022, 106296Highlights•IGF2BP2, MEIS2, and GATA6 were all found to be overexpressed in ovari...
An intact zinc finger motif of the C1B domain is critical for stability and activity of diacylglycerol kinase-ε
Available online 13 September 2022, 106295Highlights•A new fluorescent DGKε activity assay using NBD-SAG as a substrate is...
LncRNA PVT1 is a novel mediator promoting the angiogenesis response associated with collateral artery formation
Available online 27 August 2022, 106294Highlights•Both “Good CCC” coronary artery disease patients and OGD HUVECs have hig...
WD Repeat Domain 43 promotes malignant progression of non-small cell lung cancer by regulating CDK2
Available online 27 August 2022, 106293AbstractNon-small cell lung cancer (NSCLC) ranks highly among malignant tumors in t...
An overview of tools to decipher O-GlcNAcylation from historical approaches to new insights
Available online 27 August 2022, 106289AbstractO-GlcNAcylation is a post-translational modification which affects approxim...