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Mitochondria are midfield players in steroid synthesis
Available online 18 May 2023, 106431Author links open overlay panel, ABSTRACTSteroids are important membrane components an...
The role of monocyte-derived macrophages in the lung: it’s all about context
Macrophages are present in every tissue of the body where they play crucial roles in maintaining tissue homeostasis and pr...
Reduced sulfatide content in deferoxamine-induced senescent HepG2 cells
Iron chelators, such as deferoxamine, exert an anticancer effect by altering the activity of biomolecules critical for reg...
ECM2, a prognostic biomarker for lower grade glioma, serves as a potential novel target for immunotherapy
Extracellular matrix protein 2 (ECM2), which regulates cell proliferation and differentiation, has recently been reported ...
ALDOC regulated the biological function and immune infiltration of gastric cancer cells
As of 2020, gastric cancer (GC) is fatal disease worldwide, with more than 1,000,000 new cases in 2020, and its mortality ...
Pathological implications of cellular stress in cardiovascular diseases
Cell degeneration and dysfunction are among the primary causes of numerous cardiovascular diseases, leading to tissue and ...
Chidamide, a novel histone deacetylase inhibitor, inhibits laryngeal cancer progression in vitro and in vivo
Although surgery is an important treatment for laryngeal cancer, surgery has a significant negative impact on the quality ...
The endocytosis receptor megalin: From bench to bedside
Volume 157, April 2023, 106393Author links open overlay panel, , , AbstractThe large (∼600 kDa) endocytosis receptor megal...
Long non-coding RNAs: The growth controller of vascular smooth muscle cells in cardiovascular diseases
Medial vascular smooth muscle cells (VSMCs) in normal adults are lowly proliferative, synthetic, and secretory but rich in...
From Mitochondria to Cells to Humans: Targeting Bioenergetics in Aging and Disease
Available online 17 February 2023, 106391Author links open overlay panel, , ABSTRACTIn vivo control over metabolism is at ...
E2F1-mediated ectopic expression of PP1A promotes breast cancer progression via activation of YAP1
Breast cancer has become the most common malignant tumor worldwide with 70% of breast cancer being hormone receptor-positi...
Secretoglobin 3A2 protects lung from developing cigarette smoke-induced pulmonary emphysema
Chronic obstructive pulmonary disease (COPD) is mainly caused by chronic inflammation secondary to long-term inhalation ex...
G-protein signaling modulator 1 promotes colorectal cancer metastasis by PI3K/AKT/mTOR signaling and autophagy
Colorectal cancer (CRC) is one of the most common cancer types and the second leading cause of cancer-related death worldw...
Nicotinic acetylcholine receptors: key targets for attenuating neurodegenerative diseases
Organisms have developed defences against pathogens via physical, chemical, and cellular mechanisms that underlie the inna...
Molecular profiling in desmoplastic small round cell tumours
Desmoplastic small round cell tumour (DSRCT) is an ultra-rare soft tissue sarcoma that is characterised by aggressive dise...
Investigating and imaging platelets in inflammation
Volume 157, April 2023, 106373Author links open overlay panelAbstractBlood platelets are best known for their roles in hem...