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The Endolysosomal Transporter DMT1 is Required for Morphine Regulation of Neuronal Ferritin Heavy Chain
The Endolysosomal Transporter DMT1 is Required for Morphine Regulation of Neuronal Ferritin Heavy Chain
NeuroHIV and other neurologic disorders present with altered iron metabolism in central nervous system neurons. Many peopl...
Fatty Acid-Binding Protein 4 is Essential for the Inflammatory and Metabolic Response of Microglia to Lipopolysaccharide
Fatty Acid-Binding Protein 4 is Essential for the Inflammatory and Metabolic Response of Microglia to Lipopolysaccharide
Prolonged activation of microglia leads to excessive release of proinflammatory mediators, which are detrimental to brain ...
Characterization of Depression- and Anxiety-Like Behaviours in a Mouse Model of Relapsing-Remitting Multiple Sclerosis
Characterization of Depression- and Anxiety-Like Behaviours in a Mouse Model of Relapsing-Remitting Multiple Sclerosis
Relapsing-remitting multiple sclerosis (RRMS) is an autoimmune neurological disease and is the most common subtype of MS. ...
Impact of Adolescent Nicotine Exposure in Pre- and Post-natal Oxycodone Exposed Offspring
Impact of Adolescent Nicotine Exposure in Pre- and Post-natal Oxycodone Exposed Offspring
Perinatal exposure to prescription opioids pose a critical public health risk. Notably, research has found significant neu...
Effect and Mechanism of Sodium Butyrate on Neuronal Recovery and Prognosis in Diabetic Stroke
Effect and Mechanism of Sodium Butyrate on Neuronal Recovery and Prognosis in Diabetic Stroke
Ischemic stroke is a cerebrovascular lesion caused by local ischemia and hypoxia. Diabetes mellitus (DM) is a chronic infl...
Ibrutinib Delays ALS Installation and Increases Survival of SOD1G93A Mice by Modulating PI3K/mTOR/Akt Signaling
Ibrutinib Delays ALS Installation and Increases Survival of SOD1G93A Mice by Modulating PI3K/mTOR/Akt Signaling
Amyotrophic lateral sclerosis (ALS) is a fatal multisystem degenerative disorder with minimal available therapeutic. Howev...
Ginsenoside Re Mitigates Photooxidative Stress-Mediated Photoreceptor Degeneration and Retinal Inflammation
Ginsenoside Re Mitigates Photooxidative Stress-Mediated Photoreceptor Degeneration and Retinal Inflammation
Loss of photoreceptors is the central pathology accountable for irreversible vision impairment in patients with photorecep...
Maternal Immune Activation Induces Cortical Catecholaminergic Hypofunction and Cognitive Impairments in Offspring
Maternal Immune Activation Induces Cortical Catecholaminergic Hypofunction and Cognitive Impairments in Offspring
Impairment of specific cognitive domains in schizophrenia has been associated with prefrontal cortex (PFC) catecholaminerg...
Role of Dysregulated Autophagy in HIV Tat, Cocaine, and cART Mediated NLRP3 Activation in Microglia
Role of Dysregulated Autophagy in HIV Tat, Cocaine, and cART Mediated NLRP3 Activation in Microglia
Despite the ability of combination antiretroviral therapy (cART) to suppress viremia, there is persistence low levels of H...
Long-term Stimulation of α7 Nicotinic Acetylcholine Receptor Rescues Hemorrhagic Neuron Loss via Apoptosis of M1 Microglia
Long-term Stimulation of α7 Nicotinic Acetylcholine Receptor Rescues Hemorrhagic Neuron Loss via Apoptosis of M1 Microglia
We previously revealed that long-term treatment with nicotine suppresses microglial activation, resulting in a protective ...
Emphasizing the Crosstalk Between Inflammatory and Neural Signaling in Post-traumatic Stress Disorder (PTSD)
Emphasizing the Crosstalk Between Inflammatory and Neural Signaling in Post-traumatic Stress Disorder (PTSD)
Post-traumatic stress disorder (PTSD) is a chronic incapacitating condition with recurrent experience of trauma-related me...
Modafinil Improves Autism-like Behavior in Rats by Reducing Neuroinflammation
Modafinil Improves Autism-like Behavior in Rats by Reducing Neuroinflammation
To evaluate the ameliorating effect of Modafinil on neuroinflammation, behavioral, and histopathological alterations in ra...
CIDP: Analysis of Immunomarkers During COVID-19 mRNA-Vaccination and IVIg-Immunomodulation: An Exploratory Study
CIDP: Analysis of Immunomarkers During COVID-19 mRNA-Vaccination and IVIg-Immunomodulation: An Exploratory Study
Availability of COVID-19 mRNA vaccine for patients with chronic inflammatory demyelinating polyneuropathy (CIDP) treated w...
Potential Therapeutic Effects of Policosanol from Insect Wax on Caenorhabditis elegans Models of Parkinson’s Disease
Potential Therapeutic Effects of Policosanol from Insect Wax on Caenorhabditis elegans Models of Parkinson’s Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. The standard treatments for PD...
Aberrant Immunoglobulin G Glycosylation in Multiple Sclerosis
Aberrant Immunoglobulin G Glycosylation in Multiple Sclerosis
A hallmark of the inflammatory response in multiple sclerosis (MS) is the presence of intrathecal Immunoglobulin G (IgG) a...
miR-146a Dysregulates Energy Metabolism During Neuroinflammation
miR-146a Dysregulates Energy Metabolism During Neuroinflammation
Alzheimer’s disease (AD) and other neurodegenerative diseases are characterized by chronic neuroinflammation and a r...