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Disparities in Lung Cancer Death Among People with Chronic Lower Respiratory Diseases in the United States
Disparities in Lung Cancer Death Among People with Chronic Lower Respiratory Diseases in the United States
Patients with chronic lower respiratory diseases (CLRD) are at a higher risk of lung cancer. Less is known regarding how t...
Holter Monitoring and Cardiac Biomarkers in Screening for Cardiac Sarcoidosis
Holter Monitoring and Cardiac Biomarkers in Screening for Cardiac Sarcoidosis
Early detection of cardiac sarcoidosis (CS) is crucial due to its association with severe complications such as ventricula...
The Mitochondrial Fusion Promoter M1 Mitigates Cigarette Smoke-Induced Airway Inflammation and Oxidative Stress via the PI3K-AKT Signaling Pathway
The Mitochondrial Fusion Promoter M1 Mitigates Cigarette Smoke-Induced Airway Inflammation and Oxidative Stress via the PI3K-AKT Signaling Pathway
This study investigated the efficacy and underlying mechanism of the mitochondrial fusion promoter M1 in mitigating cigare...
The Associations of Long-Term Temperature and Precipitation with Chronic Respiratory Symptoms: Projections for the Changing Climate
The Associations of Long-Term Temperature and Precipitation with Chronic Respiratory Symptoms: Projections for the Changing Climate
To clarify the associations of climatic indices with chronic respiratory symptoms, with a final aim to approximate the eff...
Increase in Blood Eosinophil Count Over Time and Sputum IL8 are Associated with FEV1 Decline in Asthma
Increase in Blood Eosinophil Count Over Time and Sputum IL8 are Associated with FEV1 Decline in Asthma
Asthma is associated with accelerated rate of FEV1 decline. To determine predictive factors associated with accelerated FE...
Lung Clearance Index Improves in People with Cystic Fibrosis not Achieving a Clinical Important Difference in Forced Expiratory Volume in One Second After Elexacaftor/Tezacaftor/Ivacaftor Therapy
Lung Clearance Index Improves in People with Cystic Fibrosis not Achieving a Clinical Important Difference in Forced Expiratory Volume in One Second After Elexacaftor/Tezacaftor/Ivacaftor Therapy
In people with cystic fibrosis (pwCF), elexacaftor/tezacaftor/ivacaftor (ETI) therapy is associated with an average improv...
The Cough Response to Inhaled Mannitol in Healthy Subjects
The Cough Response to Inhaled Mannitol in Healthy Subjects
Inhaled mannitol induces bronchoconstriction and cough. This study aimed to describe the cough response to mannitol among ...
Development and Validation of a Screening Tool for Generalized Anxiety and Major Depressive Disorder in Patients with Chronic Obstructive Pulmonary Disease
Development and Validation of a Screening Tool for Generalized Anxiety and Major Depressive Disorder in Patients with Chronic Obstructive Pulmonary Disease
Anxiety and depression are often underdiagnosed in patients with chronic obstructive pulmonary disease (COPD). This study ...
The Reparative Effect of FOXM1 in Pulmonary Disease
The Reparative Effect of FOXM1 in Pulmonary Disease
FOXM1, a key member of the FOX transcription factor family, maintains cell homeostasis by accurately controlling diverse b...
Disulfiram Alleviates MTX-Induced Pulmonary Fibrosis by Inhibiting EMT in Type 2 Alveolar Epithelial Cells
Disulfiram Alleviates MTX-Induced Pulmonary Fibrosis by Inhibiting EMT in Type 2 Alveolar Epithelial Cells
Methotrexate (MTX)-induced pulmonary fibrosis is associated with high morbidity and mortality, with limited treatment opti...
Estimating the Impact of Asthma and COPD on Lung Cancer Screening in the USA
Estimating the Impact of Asthma and COPD on Lung Cancer Screening in the USA
Examine the association of asthma, COPD, and Asthma-COPD overlap (ACO) on rates of lung cancer screening. 2022 Behavior an...
IgG Concentrations Distinguish People with Cystic Fibrosis and Mycobacterium abscessus
IgG Concentrations Distinguish People with Cystic Fibrosis and Mycobacterium abscessus
Kumar K, Ponnuswamy A, Capstick TG, Chen C, McCabe D, Hurst R, Morrison L, Moore F, Gallardo M, Keane J, Harwood S, Sinnet...
Collagen-V and K-α-1 Tubulin Antibodies as Potential Markers of Unsuspected GERD-Related Lung Damage: Insights from a Cross-Sectional Analysis
Collagen-V and K-α-1 Tubulin Antibodies as Potential Markers of Unsuspected GERD-Related Lung Damage: Insights from a Cross-Sectional Analysis
Our group has proposed that aspiration of gastric contents leads to exposure of normally sequestered lung self-antigens (S...
Impact of Functional Status at the Time of Transplant on Short-Term Pediatric Lung Transplant Outcomes in the USA
Impact of Functional Status at the Time of Transplant on Short-Term Pediatric Lung Transplant Outcomes in the USA
Poor functional status is associated with pediatric lung transplant (LTx) waitlist mortality. We investigate how pre-trans...
Tidal Breathing Analysis as a Prognostic Index for Airway Obstruction Trajectory and Asthma in Preterm Infants
Tidal Breathing Analysis as a Prognostic Index for Airway Obstruction Trajectory and Asthma in Preterm Infants
An easy-to-implement and accurate lung function assessment tool for preterm infants is crucial to manage lifelong respirat...
Expression and Diagnostic Value of miR-3591-5p in Patients with Congenital Heart Disease-Associated Pulmonary Arterial Hypertension
Expression and Diagnostic Value of miR-3591-5p in Patients with Congenital Heart Disease-Associated Pulmonary Arterial Hypertension
This study explored the expression and diagnostic value of differentially expressed miR-3591-5p in congenital heart diseas...
Clinical and Functional Outcomes Associated with Quality of Life in Patients with Lymphangioleiomyomatosis: A Cross-Sectional Study
Clinical and Functional Outcomes Associated with Quality of Life in Patients with Lymphangioleiomyomatosis: A Cross-Sectional Study
Lymphangioleiomyomatosis (LAM) is a rare (twenty-one per million female inhabitants) neoplastic cystic lung disease that i...
TRIM13 Reduces Damage to Alveolar Epithelial Cells in COPD by Inhibiting Endoplasmic Reticulum Stress-Induced ER-Phagy
TRIM13 Reduces Damage to Alveolar Epithelial Cells in COPD by Inhibiting Endoplasmic Reticulum Stress-Induced ER-Phagy
Tripartite motif-containing protein 13 (TRIM13) directly or indirectly participates in autophagy and apoptosis. However, i...
Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic
Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic
Lung transplantation (LTx) is a potential intervention for end-stage COVID-19 lung disease. Current literature is sparse r...
Percent Predicted vs. Absolute Six-Minute Walk Distance as Predictors of Lung Transplant-Free Survival in Fibrosing Interstitial Lung Diseases
Percent Predicted vs. Absolute Six-Minute Walk Distance as Predictors of Lung Transplant-Free Survival in Fibrosing Interstitial Lung Diseases
Fibrosing interstitial lung diseases (ILDs) often progress despite treatment and become life-threatening, with lung transp...
Effects of Azithromycin on Blood Inflammatory Gene Expression and Cytokine Production in Sarcoidosis
Effects of Azithromycin on Blood Inflammatory Gene Expression and Cytokine Production in Sarcoidosis
In sarcoidosis granulomas, monocyte-derived macrophages are activated by pro-inflammatory cytokines including TNF and IL-6...
The Effects of Diabetes on Gas Transfer Capacity, Lung Volumes, Muscle Strength, and Cardio-pulmonary Responses During Exercise
The Effects of Diabetes on Gas Transfer Capacity, Lung Volumes, Muscle Strength, and Cardio-pulmonary Responses During Exercise
Diabetes is a risk factor for the development of vascular disease, chronic kidney disease, retinopathy, and neuropathy. Di...
Novel Therapeutic Target for ALI/ARDS: Forkhead Box Transcription Factors
Novel Therapeutic Target for ALI/ARDS: Forkhead Box Transcription Factors
ALI/ARDS can be a pulmonary manifestation of a systemic inflammatory response or a result of overexpression of the body...
Utility of the 52-Gene Risk Score to Identify Patients with Idiopathic Pulmonary Fibrosis at Greater Risk of Mortality in the Era of Antifibrotic Therapy
Utility of the 52-Gene Risk Score to Identify Patients with Idiopathic Pulmonary Fibrosis at Greater Risk of Mortality in the Era of Antifibrotic Therapy
We investigated whether a 52-gene signature was associated with transplant-free survival and other clinically meaningful o...
Increased Pneumonia Risk Associated with Concomitant Use of Inhaled Corticosteroids and Benzodiazepines: A Pharmacovigilance Analysis
Increased Pneumonia Risk Associated with Concomitant Use of Inhaled Corticosteroids and Benzodiazepines: A Pharmacovigilance Analysis
Inhaled corticosteroids (ICS) are effective in managing asthma and chronic obstructive pulmonary disease (COPD) but increa...
Exhaled Volatile Organic Compounds Detection in Pneumonia Screening: A Comprehensive Meta-analysis
Exhaled Volatile Organic Compounds Detection in Pneumonia Screening: A Comprehensive Meta-analysis
Pneumonia is a common lower respiratory tract infection, and early diagnosis is crucial for timely treatment and improved ...
The Lymphatic Highway: How Lymphatics Drive Lung Health and Disease
The Lymphatic Highway: How Lymphatics Drive Lung Health and Disease
The pulmonary lymphatic system has emerged as a critical regulator of lung homeostasis and a key contributor to the pathog...
Adam19 Deficiency Impacts Pulmonary Function: Human GWAS Follow-up in a Mouse Knockout Model
Adam19 Deficiency Impacts Pulmonary Function: Human GWAS Follow-up in a Mouse Knockout Model
Over 550 loci have been associated with human pulmonary function in genome-wide association studies (GWAS); however, the c...
Pseudomonas aeruginosa Infection and Inflammation in Cystic Fibrosis: A Pilot Study With Lung Explants and a Novel Histopathology Scoring System
Pseudomonas aeruginosa is the predominant bacterial pathogen colonizing the cystic fibrosis (CF) lung. Mixed populations o...
Efficacy and Safety of Dexmedetomidine in the Prone Position in Elderly Patients with Pneumonia: A Prospective, Double-Blind, Randomized Controlled Study
Efficacy and Safety of Dexmedetomidine in the Prone Position in Elderly Patients with Pneumonia: A Prospective, Double-Blind, Randomized Controlled Study
We aimed to identify a safe and effective method to assist older adults with pneumonia in tolerating the prone position fo...
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