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Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic (2597/2600)
Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic (2597/2600)
Lung transplantation (LTx) is a potential intervention for end-stage COVID-19 lung disease. Current literature is sparse r...
Effects of Active Chronic Cigarette-Smoke Exposure on Circulating Fibrocytes
Effects of Active Chronic Cigarette-Smoke Exposure on Circulating Fibrocytes
This study aimed to evaluate the hypothesis that active smoking impacts upon mediators and abundance of circulating fibroc...
The Diagnostic Efficiency and Safety of Transbronchial Lung Cryobiopsy Using 1.1-mm Cryoprobe in Diagnosing Interstitial Lung Disease
The Diagnostic Efficiency and Safety of Transbronchial Lung Cryobiopsy Using 1.1-mm Cryoprobe in Diagnosing Interstitial Lung Disease
Transbronchial lung cryobiopsy (TBLC) is increasingly used to diagnose interstitial lung disease (ILD). The 1.1-mm cryopro...
Association of Delirium with Long-Term Mortality in Critically Ill Patients with COPD Who Survived to Discharge: A Retrospective Cohort Study
Association of Delirium with Long-Term Mortality in Critically Ill Patients with COPD Who Survived to Discharge: A Retrospective Cohort Study
Critically ill patients with chronic obstructive pulmonary disease (COPD) face significant mortality after hospital discha...
Type 2 Biomarkers and Their Clinical Implications in Bronchiectasis: A Prospective Cohort Study
Type 2 Biomarkers and Their Clinical Implications in Bronchiectasis: A Prospective Cohort Study
Bronchiectasis is predominantly marked by neutrophilic inflammation. The relevance of type 2 biomarkers in disease severit...
Efficacy of Biologics in Patients with Allergic Bronchopulmonary Aspergillosis: A Systematic Review and Meta-Analysis
Efficacy of Biologics in Patients with Allergic Bronchopulmonary Aspergillosis: A Systematic Review and Meta-Analysis
Treatment of allergic bronchopulmonary aspergillosis (ABPA) is challenging. Biological therapies have been reported as adj...
Burden of Disease Associated with Refractory and Unexplained Chronic Cough in Canada: Results from a National Survey
Burden of Disease Associated with Refractory and Unexplained Chronic Cough in Canada: Results from a National Survey
Chronic cough (persisting for ≥ 8 weeks) is a common disorder that includes refractory chronic ...
Ultrathin Bronchoscopy Without Virtual Navigation for Diagnosis of Peripheral Lung Lesions
Ultrathin Bronchoscopy Without Virtual Navigation for Diagnosis of Peripheral Lung Lesions
The increasing incidence of encountering lung nodules necessitates an ongoing search for improved diagnostic procedures. V...
Characterizing the Racial Discrepancy in Hypoxemia Detection in Venovenous Extracorporeal Membrane Oxygenation: An Extracorporeal Life Support Organization Registry Analysis
Characterizing the Racial Discrepancy in Hypoxemia Detection in Venovenous Extracorporeal Membrane Oxygenation: An Extracorporeal Life Support Organization Registry Analysis
Skin pigmentation influences peripheral oxygen saturation (SpO2) compared to arterial saturation of oxygen (SaO2). Occult ...
Pulmonary Fibrosis Diagnosis and Disease Progression Detected Via Hair Metabolome Analysis
Pulmonary Fibrosis Diagnosis and Disease Progression Detected Via Hair Metabolome Analysis
Fibrotic interstitial lung disease is often identified late due to non-specific symptoms, inadequate access to specialist ...
Emerging Roles of Galectin-3 in Pulmonary Diseases
Emerging Roles of Galectin-3 in Pulmonary Diseases
Galectin-3 is a multifunctional protein that is involved in various physiological and pathological events. Emerging eviden...
Association of Cough Severity with Asthma Control and Quality of Life in Patients with Severe Asthma
Association of Cough Severity with Asthma Control and Quality of Life in Patients with Severe Asthma
Symptoms are important components in determining asthma control and in the adjustment of treatment levels. However, clinic...
Machine Learning from Veno-Venous Extracorporeal Membrane Oxygenation Identifies Factors Associated with Neurological Outcomes
Machine Learning from Veno-Venous Extracorporeal Membrane Oxygenation Identifies Factors Associated with Neurological Outcomes
Neurological complications are common in patients receiving veno-venous extracorporeal membrane oxygenation (VV-ECMO) supp...
Deep Learning Models for Predicting Malignancy Risk in CT-Detected Pulmonary Nodules: A Systematic Review and Meta-analysis
Deep Learning Models for Predicting Malignancy Risk in CT-Detected Pulmonary Nodules: A Systematic Review and Meta-analysis
There has been growing interest in using artificial intelligence/deep learning (DL) to help diagnose prevalent diseases ea...
Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry
Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry
Pulmonary fibrosis is a characteristic of various interstitial lung diseases (ILDs) with differing etiologies. Clinical tr...
Serum Free Fatty Acid Concentration Predicts ARDS after Off-Pump CABG: A Prospective Observational Study
Serum Free Fatty Acid Concentration Predicts ARDS after Off-Pump CABG: A Prospective Observational Study
Free fatty acids (FFAs) are established risk factors for various cardiovascular and metabolic disorders. Elevated FFAs can...
Associations of the Serum KL-6 with Severity and Prognosis in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Associations of the Serum KL-6 with Severity and Prognosis in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
As a biomarker of alveolar-capillary basement membrane injury, Krebs von den Lungen-6 (KL-6) is involved in the occurrence...
Cough Response to High-Dose Inhaled Corticosteroids in Patients with Chronic Cough and Fractional Exhaled Nitric Oxide Levels ≥ 25 ppb: A Prospective Study
Cough Response to High-Dose Inhaled Corticosteroids in Patients with Chronic Cough and Fractional Exhaled Nitric Oxide Levels ≥ 25 ppb: A Prospective Study
This study aimed to investigate the effects of high-dose inhaled corticosteroids (ICS) on chronic cough patients with elev...
Airway and Systemic Immunoglobulin Profiling and Immune Response in Adult Asthma
Airway and Systemic Immunoglobulin Profiling and Immune Response in Adult Asthma
Immunoglobulins play a vital role in host immune response and in the pathogenesis of conditions like asthma. Therapeutic a...
Interstitial Lung Disease and Progressive Pulmonary Fibrosis: a World Trade Center Cohort 20-Year Longitudinal Study
Interstitial Lung Disease and Progressive Pulmonary Fibrosis: a World Trade Center Cohort 20-Year Longitudinal Study
World Trade Center (WTC) exposure is associated with obstructive airway diseases and sarcoidosis. There is limited researc...
ECMO Bridge to Lung Transplant in Children with Idiopathic Pulmonary Arterial Hypertension
ECMO Bridge to Lung Transplant in Children with Idiopathic Pulmonary Arterial Hypertension
Idiopathic pulmonary arterial hypertension (IPAH) represents an important clinical indication for lung transplant (LTx) in...
The Synthetic Surfactant CHF5633 Restores Lung Function and Lung Architecture in Severe Acute Respiratory Distress Syndrome in Adult Rabbits
The Synthetic Surfactant CHF5633 Restores Lung Function and Lung Architecture in Severe Acute Respiratory Distress Syndrome in Adult Rabbits
Acute respiratory distress syndrome (ARDS) is a major cause of hypoxemic respiratory failure in adults. In ARDS extensive ...
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration and Next Generation Sequencing Yields
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration and Next Generation Sequencing Yields
The use of endobronchial ultrasound (EBUS) is standard practice for lung cancer diagnosis and staging. Next generation seq...
Neutralization of CX3CL1 Attenuates TGF-β-Induced Fibroblast Differentiation Through NF-κB Activation and Mitochondrial Dysfunction in Airway Fibrosis
Neutralization of CX3CL1 Attenuates TGF-β-Induced Fibroblast Differentiation Through NF-κB Activation and Mitochondrial Dysfunction in Airway Fibrosis
Severe asthma, characterized by inflammation and airway remodeling, involves fibroblast differentiation into myofibroblast...
Osteoprotegerin is an Early Marker of the Fibrotic Process and of Antifibrotic Treatment Responses in Ex Vivo Lung Fibrosis
Osteoprotegerin is an Early Marker of the Fibrotic Process and of Antifibrotic Treatment Responses in Ex Vivo Lung Fibrosis
Lung fibrosis is a chronic lung disease with a high mortality rate with only two approved drugs (pirfenidone and nintedani...
Heat-Induced Secretion of Heat Shock Proteins 70 and 90 Does not Affect the Expression of the Glucocorticoid Receptor in Primary Airway Cells in COPD
Heat-Induced Secretion of Heat Shock Proteins 70 and 90 Does not Affect the Expression of the Glucocorticoid Receptor in Primary Airway Cells in COPD
The response to glucocorticoids is hampered in many COPD patients by a yet unknown mechanism. Earlier we reported that sho...
Commentary: Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two‑Sample Mendelian Randomization Study
Commentary: Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two‑Sample Mendelian Randomization Study
Author notesQiong Wen and Li Li are co-corresponding authors.Authors and AffiliationsDepartment of Oncology, The First Aff...
Genetic Spectrum and Clinical Characteristics of Patients with Primary Ciliary Dyskinesia: a Belgian Single Center Study
Genetic Spectrum and Clinical Characteristics of Patients with Primary Ciliary Dyskinesia: a Belgian Single Center Study
We aimed to examine the correlation between clinical characteristics and the pathogenic gene variants in patients with Pri...
Dysphagia as a Missing Link Between Post-surgical- and Opioid-Related Pneumonia
Dysphagia as a Missing Link Between Post-surgical- and Opioid-Related Pneumonia
Postoperative pneumonia remains a common complication of surgery, despite increased attention. The purpose of our study wa...
First Exploration of the Altered Microbial Gut–Lung Axis in the Pathogenesis of Human Refractory Chronic Cough
First Exploration of the Altered Microbial Gut–Lung Axis in the Pathogenesis of Human Refractory Chronic Cough
Cough represents a natural mechanism that plays an important defensive role in the respiratory tract, but in some conditio...
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