×
Close
註冊
登入
主页
用户
博客
照片
视频
医学图书S馆
医学图书M馆
医学图书D馆
医学术语
群组
活动
用户工具
用户指南
问答
谁看过我
反馈
语言
English
中文
推广
×
Close
CN1699 Our Business - Guide for Agents
分类
Biochemistry & Molecular Biology
28644
Global Medical University
4867
Allergy
1738
Anatomy & Morphology
1493
Andrology
414
Anesthesia & Intensive Care
1185
Anesthesiology
5280
Audiology & Speech-Language Pathology
317
Behavioral Sciences
100
Biochemical Research Methods
6594
Biodiversity Conservation
276
Biology
8008
Biophysics
7859
Biotechnology & Applied Microbiology
7900
Cardiac & Cardiovascular Systems
30092
Cardiovascular & Respiratory Systems
1360
Cell & Tissue Engineering
633
Cell Biology
10592
Chemistry, Analytical
4104
Chemistry, Applied
10882
Chemistry, Medicinal
8311
Chemistry, Multidisciplinary
18274
Clinical Immunology & Infectious Disease
424
Clinical Medicine
8595
Clinical Neurology
15848
Clinical Psychology & Psychiatry
1262
Critical Care Medicine
3053
Dentistry, Oral Surgery & Medicine
12559
Dermatology
7527
Developmental Biology
6815
Ecology
637
Education, Scientific Disciplines
1826
Emergency Medicine
3856
Endocrinology, Metabolism & Nutrition
22915
Engineering, Biomedical
3476
Entomology
414
Environmental Medicine & Public Health
4532
Evolutionary Biology
245
Gastroenterology & Hepatology
11489
General & Internal Medicine
6852
Genetics & Heredity
14377
Geriatrics & Gerontology
4871
Gerontology
323
Health Care Sciences & Services
15200
Health Policy & Services
567
Hematology
5314
Immunology
24225
Infectious Diseases
13358
Integrative & Complementary Medicine
2651
Medical Ethics
1113
Medical Informatics
2030
Medical Laboratory Technology
433
Medicine, General & Internal
43600
Medicine, Legal
470
Medicine, Research & Experimental
17050
Microbiology
22309
Mycology
0
Nanoscience & Nanotechnology
4882
Neuroimaging
1223
Neurology
4285
Neurosciences
37965
Nursing
9051
Nutrition & Dietetics
7682
Obstetrics & Gynecology
7872
Oncology
50615
Ophthalmology
9246
Optics
3884
Orthopedics
11061
Orthopedics, Rehabilitation & Sports Medicine
1670
Otolaryngology
1464
Otorhinolaryngology
4675
Parasitology
1009
Pathology
4721
Pediatrics
20562
Peripheral Vascular Disease
4505
Pharmacology & Pharmacy
32997
Pharmacology/Toxicology
11836
Physiology
8760
Polymer Science
525
Primary Health Care
774
Psychiatry
18469
Psychology
4899
Psychology, Applied
81
Psychology, Biological
315
Psychology, Clinical
759
Psychology, Developmental
210
Psychology, Educational
132
Psychology, Experimental
112
Psychology, Mathematical
0
Psychology, Multidisciplinary
1544
Psychology, Psychoanalysis
41
Psychology, Social
106
Public Health & Health Care Science
2164
Public, Environmental & Occupational Health
26511
Quantum Science & Technology
0
Radiology, Nuclear Medicine & Imaging
11739
Radiology, Nuclear Medicine & Medical Imaging
7580
Rehabilitation
2880
Remote Sensing
0
Reproductive Biology
2677
Reproductive Medicine
1125
Research/Laboratory Medicine & Medical Technology
3790
Respiratory System
6863
Rheumatology
5554
Social Sciences, Biomedical
1137
Substance Abuse
2604
Surgery
32424
Toxicology
4123
Transplantation
917
Tropical Medicine
314
Urology & Nephrology
12393
Veterinary Sciences
35
Virology
2315
Zoology
0
渠道
PROTEIN SCIENCE
152
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
223
ANTIOXIDANTS
2594
BIOMOLECULES
2187
BIOORGANIC CHEMISTRY
1595
CELL AND BIOSCIENCE
478
CELLULAR & MOLECULAR BIOLOGY LETTERS
222
CELLULAR AND MOLECULAR LIFE SCIENCES
1142
COLLOIDS AND SURFACES B-BIOINTERFACES
1438
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
1308
CYTOKINE
621
CYTOKINE & GROWTH FACTOR REVIEWS
129
FREE RADICAL BIOLOGY AND MEDICINE
974
GENOME RESEARCH
440
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
20
INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY
250
JOURNAL OF BIOLOGICAL CHEMISTRY
2276
JOURNAL OF CELLULAR BIOCHEMISTRY
110
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
154
JOURNAL OF GENETICS AND GENOMICS
417
JOURNAL OF INORGANIC BIOCHEMISTRY
666
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
101
JOURNAL OF LIPID RESEARCH
33
JOURNAL OF MOLECULAR BIOLOGY
697
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
376
MOLECULAR BIOLOGY
213
MOLECULAR CARCINOGENESIS
63
NATURE CHEMICAL BIOLOGY
624
NATURE PROTOCOLS
366
NEUROCHEMISTRY INTERNATIONAL
346
PROGRESS IN LIPID RESEARCH
0
REDOX BIOLOGY
1
SCIENCE SIGNALING
181
SIGNAL TRANSDUCTION AND TARGETED THERAPY
951
BIOCHEMISTRY AND CELL BIOLOGY
146
BIOMEDICAL JOURNAL
0
BIOORGANIC & MEDICINAL CHEMISTRY
1
BIOPHYSICAL CHEMISTRY
0
BIOPOLYMERS
28
BIOTECHNIQUES
348
BMC BIOCHEMISTRY
122
CELL BIOCHEMISTRY AND FUNCTION
55
CHEMBIOCHEM
352
CHEMICAL BIOLOGY & DRUG DESIGN
164
CURRENT ISSUES IN MOLECULAR BIOLOGY
565
FRONTIERS IN MOLECULAR BIOSCIENCES
2672
JOURNAL OF FOOD BIOCHEMISTRY
259
JOURNAL OF MOLECULAR RECOGNITION
35
LIPIDS
23
NEUROCHEMICAL RESEARCH
606
PHYSICAL BIOLOGY
95
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
6
LIPIDS IN HEALTH AND DISEASE
420
VITAMINS AND HORMONES
225
BIOCHEMISTRY INSIGHTS
8
BIOCHEMISTRY MOSCOW-SUPPLEMENT SERIES B-BIOMEDICAL CHEMISTRY
57
INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY
187
PROTEOMES
63
MOLECULAR BIOLOGY RESEARCH COMMUNICATIONS
55
REVIEWS OF PHYSIOLOGY BIOCHEMISTRY AND PHARMACOLOGY
64
GENES & GENOMICS
369
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
298
JOURNAL OF BIOMOLECULAR NMR
73
SCI时时刷
search
全部
推荐
+
Phylogenetic convergence of phase separation and mitotic function in the disordered protein BuGZ
Abstract Intrinsically disordered proteins (IDPs) effect biological function despite their sequence-encoded lack of prefer...
Protein Science
comment
0
thumb_up
0
A novel and unique ATP hydrolysis to AMP by a human Hsp70 Binding immunoglobin protein (BiP)
Abstract Hsp70s are ubiquitous and highly conserved molecular chaperones. They play crucial roles in maintaining cellular ...
Protein Science
comment
0
thumb_up
0
Completing the family of human EH domains: Solution structure of the internal EH domain of γ‐synergin
Abstract Eps15 homology (EH) domains are universal interaction domains to establish networks of protein-protein interactio...
Protein Science
comment
0
thumb_up
0
Atomic View of an Amyloid Dodecamer Exhibiting Selective Cellular Toxic Vulnerability in Acute Brain Slices
Abstract Atomic structures of amyloid oligomers that capture the neurodegenerative disease pathology are essential to unde...
Protein Science
comment
0
thumb_up
0
A novel and unique ATP hydrolysis to AMP by a human Hsp70 BiP
Abstract Hsp70s are ubiquitous and highly conserved molecular chaperones. They play crucial roles in maintaining cellular ...
Protein Science
comment
0
thumb_up
0
A novel violet fluorescent protein contains a unique oxidized tyrosine as the simplest chromophore ever reported in fluorescent proteins
Abstract We describe an engineered violet fluorescent protein from the lancelet Branchiostoma floridae (bfVFP). This is th...
Protein Science
comment
0
thumb_up
0
Double mutations far from the active site affect cold‐activity in an Antarctic halophilic β‐galactosidase
Abstract The Antarctic haloarchaeon, Halorubrum lacusprofundi, contains a polyextremophilic family 42 β-galactosidas...
Protein Science
comment
0
thumb_up
0
Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes
Abstract Sequence variation in related proteins is an important characteristic that modulates activity and selectivity. An...
Protein Science
comment
0
thumb_up
0
Modeling the stimulation by glutathione of the steady state kinetics of an adenosine triphosphate binding cassette transporter
Abstract We report the steady state ATPase activities of the ATP Binding Cassette (ABC) exporter NaAtm1 in the absence and...
Protein Science
comment
0
thumb_up
0
Structure of the human Ccr4‐Not nuclease module using X‐ray crystallography and electron paramagnetic resonance spectroscopy distance measurements
Abstract Regulated degradation of mature, cytoplasmic mRNA is a key step in eukaryotic gene regulation. This process is ty...
Protein Science
comment
0
thumb_up
0
The molecular basis for the development of Adult T‐cell leukemia/lymphoma in patients with an IRF4K59R mutation
Abstract Interferon regulatory factor 4 (IRF4) is an essential regulator in the development of many immune cells, includin...
Protein Science
comment
0
thumb_up
0
Rapid Directed Molecular Evolution of Fluorescent Proteins in Mammalian Cells
Abstract In vivo imaging of model organisms is heavily reliant on fluorescent proteins with high intracellular brightness....
Protein Science
comment
0
thumb_up
0
Thioesterase enzyme families: functions, structures, and mechanisms
Abstract Thioesterases are enzymes that hydrolyze thioester bonds in numerous biochemical pathways, for example in fatty a...
Protein Science
comment
0
thumb_up
0
High‐throughput Cell‐free Screening of Eukaryotic Membrane Protein Expression in Lipidic Mimetics
Abstract Membrane proteins play essential roles in cellular function and metabolism. Nonetheless, biophysical and structur...
Protein Science
comment
0
thumb_up
0
Molecular dissection of a dedicated formaldehyde dehydrogenase from Mycobacterium smegmatis
Abstract Accumulation of formaldehyde, a highly reactive molecule, in the cell is toxic, and requires detoxification for t...
Protein Science
comment
0
thumb_up
0
Three‐repeat and four‐repeat Tau isoforms form different oligomers
Abstract Different tauopathies are characterized by isoform-specific composition of the aggregates found in the brain and ...
Protein Science
comment
0
thumb_up
0
Activity and substrate specificity of lytic polysaccharide monooxygenases: an ATR FTIR‐based sensitive assay tested on a novel species from Pseudomonas putida
Abstract Pseudomonas putida W619 is a soil Gram-negative bacterium commonly used in environmental studies thanks to its ab...
Protein Science
comment
0
thumb_up
0
The Ca2+ response of a smart forisome protein is dependent on polymerization
Abstract Forisomes are giant self-assembling mechanoproteins that undergo reversible structural changes in response to Ca2...
Protein Science
comment
0
thumb_up
0
Tools 2022: A compilation of tools for protein science
Protein Science, the flagship journal of The Protein Society, serves an international forum for publishing original report...
Protein Science
comment
0
thumb_up
0
Characterization of protein‐ligand binding interactions of enoyl‐ACP reductase (FabI) by native MS reveals allosteric effects of coenzymes and the inhibitor triclosan
Abstract The enzyme enoyl-ACP reductase (also called FabI in bacteria) is an essential member of the fatty acid synthase I...
Protein Science
comment
0
thumb_up
0
Structural and Functional Characterization of Fosfomycin Resistance Conferred by FosB from Enterococcus faecium
Abstract The Gram-positive pathogen Enterococcus faecium is one of the leading causes of hospital-acquired vancomycin resi...
Protein Science
comment
0
thumb_up
0
Stimulation of the steady state ATPase kinetics of the ABC exporter NaAtm1 by a transported substrate GSSG
Abstract We report the steady state ATPase activities of the ATP Binding Cassette (ABC) exporter NaAtm1 in the absence and...
Protein Science
comment
0
thumb_up
0
Design principles that protect the proteasome from self‐destruction
Abstract The proteasome is a powerful intracellular protease that can degrade effectively any protein, self or foreign, fo...
Protein Science
comment
0
thumb_up
0
A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels
Abstract Protein stability can be fine-tuned by modifying different structural features such as hydrogen-bond networks, sa...
Protein Science
comment
0
thumb_up
0
Structural and dynamic studies of the peptidase domain from Clostridium thermocellum PCAT1
Abstract The export of antimicrobial peptides is mediated by diverse mechanisms in bacterial quorum sensing pathways. One ...
Protein Science
comment
0
thumb_up
0
A New Strategy to Reconcile Amyloid Cross‐seeding and Amyloid Prevention in a Binary System of α‐synuclein Fragmental Peptide and hIAPP
Abstract Amyloid cross-seeding and amyloid inhibition are two different research subjects being studied separately for dif...
Protein Science
comment
0
thumb_up
0
Crystal structure of semisynthetic obelin‐v
Abstract Coelenterazine-v (CTZ-v), a synthetic derivative with an additional benzyl ring, yields a bright bioluminescence ...
Protein Science
comment
0
thumb_up
0
Analysis of protein–ligand interactions from titrations and nuclear magnetic resonance relaxation dispersions
Abstract We present PLIS, a publicly available, open-source software for the determination of protein–ligand dissoc...
Protein Science
comment
0
thumb_up
0
Crystal structure of semi‐synthetic obelin‐v
Abstract Coelenterazine-v (CTZ-v), a synthetic derivative with an additional benzyl ring, yields a bright bioluminescence ...
Protein Science
comment
0
thumb_up
0
Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy
Abstract PTPN2 is an important protein tyrosine phosphatase (PTP) that plays a key role in cell signaling. Deletions or in...
Protein Science
comment
0
thumb_up
0
阅读更多
Modal title
×
Modal title
×
分享
登入
Global News and Health Forum
Join Now!
馬上登入
記住我
忘記密碼?
或者使用
Linkedin