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Mifepristone as Bridge or Adjunct Therapy in the Management of Challenging Cushing Disease Cases
Mifepristone as Bridge or Adjunct Therapy in the Management of Challenging Cushing Disease Cases
Establishing a definitive diagnosis of Cushing disease (CD), given its clinical and biochemical heterogeneity, initiating ...
Dyslipidemia Increases the Risk of Severe COVID-19: A Systematic Review, Meta-analysis, and Meta-regression
Dyslipidemia Increases the Risk of Severe COVID-19: A Systematic Review, Meta-analysis, and Meta-regression
Objective:This systematic review and meta-analysis aimed to evaluate whether dyslipidemia affects the mortality and severi...
Therapeutic Potential of Peptides Derived from Animal Venoms: Current Views and Emerging Drugs for Diabetes
Therapeutic Potential of Peptides Derived from Animal Venoms: Current Views and Emerging Drugs for Diabetes
The therapeutic potential of venom-derived drugs is evident today. Currently, several significant drugs are FDA approved f...
Diabetic Ketoacidosis Management and Treatment Outcome at Medical Ward of Shashemene Referral Hospital, Ethiopia: A Retrospective Study
Diabetic Ketoacidosis Management and Treatment Outcome at Medical Ward of Shashemene Referral Hospital, Ethiopia: A Retrospective Study
Background:Diabetic Ketoacidosis (DKA) is the most common and yet potentially life-threatening acute complication of diabe...
Search for Genetic Predictors of Adult Autoimmune Polyendocrine Syndrome in Monozygotic Twins
Search for Genetic Predictors of Adult Autoimmune Polyendocrine Syndrome in Monozygotic Twins
Autoimmune polyendocrine syndromes (APS) are a heterogeneous group of diseases characterized by the presence of autoimmune...
Glycemic Variability in Type 1 Diabetes Mellitus Saudis Using Ambulatory Glucose Profile
Glycemic Variability in Type 1 Diabetes Mellitus Saudis Using Ambulatory Glucose Profile
Background:Glucose variability (GV) is a common and challenging clinical entity in the management of people with type 1 di...
Frequency of Parathyroid Hormone Assessment in the Evaluation of Hypercalcemia. A Comparison Between Patients With and Without a History of Malignancy in a 20-year Dataset of 20,954 Patients
Frequency of Parathyroid Hormone Assessment in the Evaluation of Hypercalcemia. A Comparison Between Patients With and Without a History of Malignancy in a 20-year Dataset of 20,954 Patients
Background:The purpose of this study was to evaluate whether a prior diagnosis of malignancy affected the assessment of pa...
A Community Pharmacy-Based Intervention in the Matrix of Type 2 Diabetes Mellitus Outcomes (CPBI-T2DM): A Cluster Randomized Controlled Trial
A Community Pharmacy-Based Intervention in the Matrix of Type 2 Diabetes Mellitus Outcomes (CPBI-T2DM): A Cluster Randomized Controlled Trial
Introduction:Egypt has the ninth highest diabetes mellitus (DM) prevalence in the world. There is a growing interest in co...
Pleiotropic Benefits of DPP-4 Inhibitors Beyond Glycemic Control
Pleiotropic Benefits of DPP-4 Inhibitors Beyond Glycemic Control
Dipeptidyl peptidase (DPP)-4 inhibitors are oral anti-diabetic medications that block the activity of the ubiquitous enzym...
Role of Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists in Hypoglycemia
Role of Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists in Hypoglycemia
A relatively recent addition to the arsenal of antidiabetic drugs used for the treatment of type 2 diabetes mellitus (T2DM...
Understanding the Pancreatic Islet Microenvironment in Cystic Fibrosis and the Extrinsic Pathways Leading to Cystic Fibrosis Related Diabetes
Understanding the Pancreatic Islet Microenvironment in Cystic Fibrosis and the Extrinsic Pathways Leading to Cystic Fibrosis Related Diabetes
Cystic fibrosis (CF) is an autosomal recessive chronic condition effecting approximately 70 000 to 100 000 people globally...
Multicenter, Open-Label, 2-Arm, Pilot Trial for Safe Reduction of Basal Insulin Dose Combined with SGLT2 Inhibitor in Type 1 Diabetes Mellitus: Study Protocol for a RISING-STAR Trial
Multicenter, Open-Label, 2-Arm, Pilot Trial for Safe Reduction of Basal Insulin Dose Combined with SGLT2 Inhibitor in Type 1 Diabetes Mellitus: Study Protocol for a RISING-STAR Trial
Background:The safe method of instructing insulin dose reduction in combination with SGLT2 inhibitors, dapagliflozin for p...
Xenin and Related Peptides: Potential Therapeutic Role in Diabetes and Related Metabolic Disorders
Xenin and Related Peptides: Potential Therapeutic Role in Diabetes and Related Metabolic Disorders
Xenin bioactivity and its role in normal physiology has been investigated by several research groups since its discovery i...
A Review of Coumarins and Coumarin-Related Compounds for Their Potential Antidiabetic Effect
A Review of Coumarins and Coumarin-Related Compounds for Their Potential Antidiabetic Effect
Background and aims:Worldwide, type 2 diabetes mellitus accounts for a considerable burden of disease, with an estimated g...
Sedentary Behavior Counseling Intervention in Aging People With Type 2 Diabetes: A Feasibility Study
Sedentary Behavior Counseling Intervention in Aging People With Type 2 Diabetes: A Feasibility Study
This study examined the feasibility and effect of sedentary behavior (SB) counseling on total sitting time (TST) and glyce...
Associations Between Glucose Tolerance, Insulin Secretion, Muscle and Fat Mass in Cystic Fibrosis
Associations Between Glucose Tolerance, Insulin Secretion, Muscle and Fat Mass in Cystic Fibrosis
Background:A frequent comorbidity in cystic fibrosis (CF) is CF related diabetes (CFRD) caused by a gradual decline in ins...
Real-World Clinical Experience on the Usage of High-Dose Metformin (1500-2500 mg/day) in Type 2 Diabetes Management
Real-World Clinical Experience on the Usage of High-Dose Metformin (1500-2500 mg/day) in Type 2 Diabetes Management
Background:To evaluate the clinical characteristics, treatment patterns, and clinical effectiveness and safety of high dos...
Islet Function in the Pathogenesis of Cystic Fibrosis-Related Diabetes Mellitus
Islet Function in the Pathogenesis of Cystic Fibrosis-Related Diabetes Mellitus
Cystic fibrosis-related diabetes mellitus (CFRD) is the most common non-pulmonary co-morbidity in cystic fibrosis (CF). CF...
Adrenal Insufficiency Secondary to Septic Shock in a Male Patient with Iatrogenic Cushing’s Syndrome: 2 sides of the Same Coin?
Adrenal Insufficiency Secondary to Septic Shock in a Male Patient with Iatrogenic Cushing’s Syndrome: 2 sides of the Same Coin?
Cushing’s syndrome causes increased morbidity and mortality due to cardiovascular and infectious diseases. Exogenous Cushi...
Utility of Cannulated Prolactin to Exclude Stress Hyperprolactinemia in Patients with Persistent Mild Hyperprolactinemia
Utility of Cannulated Prolactin to Exclude Stress Hyperprolactinemia in Patients with Persistent Mild Hyperprolactinemia
Background:Stress-induced hyperprolactinemia can be difficult to differentiate from true hyperprolactinema and may result ...
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