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Functional comorbidities and brain tissue changes before and after lung transplant in adults
Functional comorbidities and brain tissue changes before and after lung transplant in adults
BackgroundAdults undergoing lung transplant, as a lifesaving treatment for end stage lung disease, exhibit high levels of ...
Caspase-dependent apoptosis induces reactivation and gliogenesis of astrocytes in adult mice
Caspase-dependent apoptosis induces reactivation and gliogenesis of astrocytes in adult mice
Astrocytes play an important role in increasing synaptic plasticity, regulating endogenous homeostasis, and contributing t...
Improved neuron protection following cortical injury in the absence of Semaphorin4B
Improved neuron protection following cortical injury in the absence of Semaphorin4B
Injury to the central nervous system induces neuronal cell death and astrogliosis, an astrocyte-mediated response that has...
Corrigendum: Acute ablation of cortical pericytes leads to rapid neurovascular uncoupling
Corrigendum: Acute ablation of cortical pericytes leads to rapid neurovascular uncoupling
The original version of this article has been updated.In the published article, there was a mistake in the Funding stateme...
Visualization of real-time receptor endocytosis in dopamine neurons enabled by NTSR1-Venus knock-in mice
Visualization of real-time receptor endocytosis in dopamine neurons enabled by NTSR1-Venus knock-in mice
Dopamine (DA) neurons are primarily concentrated in substantia nigra (SN) and ventral tegmental area (VTA). A subset of th...
Restoration of spinal cord injury: From endogenous repairing process to cellular therapy
Restoration of spinal cord injury: From endogenous repairing process to cellular therapy
Spinal cord injury (SCI) disrupts neurological pathways and impacts sensory, motor, and autonomic nerve function. There is...
Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway
Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway
BackgroundMutations in lipoxygenase homology domain 1 (LOXHD1) cause autosomal recessive inheritance, leading to high-freq...
Oligodendroglial primary cilium heterogeneity during development and demyelination/remyelination
Oligodendroglial primary cilium heterogeneity during development and demyelination/remyelination
The primary cilium (PC) has emerged as an indispensable cellular antenna essential for signal transduction of important ce...
Plasticity impairment alters community structure but permits successful pattern separation in a hippocampal network model
Plasticity impairment alters community structure but permits successful pattern separation in a hippocampal network model
Patients who suffer from traumatic brain injury (TBI) often complain of learning and memory problems. Their symptoms are p...
MicroRNA cerebrospinal fluid profile during the early brain injury period as a biomarker in subarachnoid hemorrhage patients
MicroRNA cerebrospinal fluid profile during the early brain injury period as a biomarker in subarachnoid hemorrhage patients
IntroductionDelayed cerebral ischemia (DCI) is a dreadful complication present in up to 30% of patients with spontaneous s...
Learning from magnetotactic bacteria: mms6 protects stem cells from oxidative damage
Learning from magnetotactic bacteria: mms6 protects stem cells from oxidative damage
Oxidative damage generally exists in stroke and impairs stem cells’ survival; however, the problem is difficult to treat. ...
Pyroptosis in spinal cord injury
Pyroptosis in spinal cord injury
Spinal cord injury (SCI) often brings devastating consequences to patients and their families. Pathophysiologically, the p...
Role of hippocampal circKcnk9 in visceral hypersensitivity and anxiety comorbidity of irritable bowel syndrome
Role of hippocampal circKcnk9 in visceral hypersensitivity and anxiety comorbidity of irritable bowel syndrome
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterized by recurrent visceral pain and altered ...
Voltage-gated sodium channels in diabetic sensory neuropathy: Function, modulation, and therapeutic potential
Voltage-gated sodium channels in diabetic sensory neuropathy: Function, modulation, and therapeutic potential
Voltage-gated sodium channels (NaV) are the main contributors to action potential generation and essential players in esta...
The MeshCODE to scale—visualising synaptic binary information
The MeshCODE to scale—visualising synaptic binary information
The Mercator projection map of the world provides a useful, but distorted, view of the relative scale of countries. Curren...
Investigations into photoreceptor energy metabolism during experimental retinal detachment
Investigations into photoreceptor energy metabolism during experimental retinal detachment
Retinal detachment is a sight-threatening disorder, which occurs when the photoreceptors are separated from their vascular...
Ferroptosis-related biomarkers for Alzheimer’s disease: Identification by bioinformatic analysis in hippocampus
Ferroptosis-related biomarkers for Alzheimer’s disease: Identification by bioinformatic analysis in hippocampus
BackgroundGlobally, Alzheimer’s Disease (AD) accounts for the majority of dementia, making it a public health concern. AD ...
Improving translatability of spinal cord injury research by including age as a demographic variable
Improving translatability of spinal cord injury research by including age as a demographic variable
Pre-clinical and clinical spinal cord injury (SCI) studies differ in study design, particularly in the demographic charact...
The alternative proteome in neurobiology
The alternative proteome in neurobiology
Translation involves the biosynthesis of a protein sequence following the decoding of the genetic information embedded in ...
Application and prospects of somatic cell reprogramming technology for spinal cord injury treatment
Application and prospects of somatic cell reprogramming technology for spinal cord injury treatment
Spinal cord injury (SCI) is a serious neurological trauma that is challenging to treat. After SCI, many neurons in the inj...
The effects of graft source and orientation on outcomes after ablation of a branched peripheral nerve
The effects of graft source and orientation on outcomes after ablation of a branched peripheral nerve
Segmental peripheral nerve injuries (PNI) are the most common cause of enduring nervous system dysfunction. The peripheral...