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Manipulation of DHPS activity affects dendritic morphology and expression of synaptic proteins in primary rat cortical neurons
Manipulation of DHPS activity affects dendritic morphology and expression of synaptic proteins in primary rat cortical neurons
Deoxyhypusine synthase (DHPS) catalyzes the initial step of hypusine incorporation into the eukaryotic initiation factor 5...
The role of ferroptosis in neurodegenerative diseases
The role of ferroptosis in neurodegenerative diseases
Ferroptosis represents an iron− and lipid peroxidation (LPO)-mediated form of regulated cell death (RCD). Recent evidence ...
Noise-induced cochlear synaptopathy in C57BL/6 N mice as a function of trauma strength: ribbons are more vulnerable than postsynapses
Noise-induced cochlear synaptopathy in C57BL/6 N mice as a function of trauma strength: ribbons are more vulnerable than postsynapses
Noise-induced cochlear synaptopathy is characterized by irreversible loss of synapses between inner hair cells (IHCs) and ...
Ammonium chloride reduces excitatory synaptic transmission onto CA1 pyramidal neurons of mouse organotypic slice cultures
Ammonium chloride reduces excitatory synaptic transmission onto CA1 pyramidal neurons of mouse organotypic slice cultures
Acute liver dysfunction commonly leads to rapid increases in ammonia concentrations in both the serum and the cerebrospina...
A novel KCNC3 gene variant in the voltage-dependent Kv3.3 channel in an atypical form of SCA13 with dominant central vertigo
A novel KCNC3 gene variant in the voltage-dependent Kv3.3 channel in an atypical form of SCA13 with dominant central vertigo
Potassium channel mutations play an important role in neurological diseases, such as spinocerebellar ataxia (SCA). SCA is ...
Loss of C1q alters the auditory brainstem response
Loss of C1q alters the auditory brainstem response
Neural circuits in the auditory brainstem compute interaural time and intensity differences used to determine the location...
A novel loss-of-function KCNB1 gene variant in a twin with global developmental delay and seizures
A novel loss-of-function KCNB1 gene variant in a twin with global developmental delay and seizures
Human voltage-gated potassium (Kv) channels are expressed by a 40-member gene family that is essential for normal electric...
Quantitative, real-time imaging of spreading depolarization-associated neuronal ROS production
Quantitative, real-time imaging of spreading depolarization-associated neuronal ROS production
Spreading depolarization (SD) causes a massive neuronal/glial depolarization, disturbs ionic homeostasis and deranges neur...
Editorial: Gateways to the brain: vascular-glial-immune network in health and disease
The brain, a vital organ, is safeguarded by biological barriers such as the blood-brain barrier (BBB), 17 which regulates ...
ALS-like pathology diminishes swelling of spinal astrocytes in the SOD1 animal model
ALS-like pathology diminishes swelling of spinal astrocytes in the SOD1 animal model
Astrocytes are crucial for the functioning of the nervous system as they maintain the ion homeostasis via volume regulatio...
Corrigendum: Neuroprotection by upregulation of the major histocompatibility complex class I (MHC I) in SOD1G93A mice
Corrigendum: Neuroprotection by upregulation of the major histocompatibility complex class I (MHC I) in SOD1G93A mice
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Transgenic zebrafish as a model for investigating diabetic peripheral neuropathy: investigation of the role of insulin signaling
Transgenic zebrafish as a model for investigating diabetic peripheral neuropathy: investigation of the role of insulin signaling
Diabetic peripheral neuropathy (DPN), a complication of diabetes mellitus (DM), is a neurodegenerative disorder that resul...
Activation of arginine vasopressin receptor 1a reduces inhibitory synaptic currents at reciprocal synapses in the mouse accessory olfactory bulb
Activation of arginine vasopressin receptor 1a reduces inhibitory synaptic currents at reciprocal synapses in the mouse accessory olfactory bulb
Central arginine vasopressin (AVP) facilitates social recognition and modulates many complex social behaviors in mammals t...
GABAergic dysfunction in postmortem dorsolateral prefrontal cortex: implications for cognitive deficits in schizophrenia and affective disorders
GABAergic dysfunction in postmortem dorsolateral prefrontal cortex: implications for cognitive deficits in schizophrenia and affective disorders
The microcircuitry within superficial layers of the dorsolateral prefrontal cortex (DLPFC), composed of excitatory pyramid...
Editorial: 15 years of Frontiers in Cellular Neuroscience: the role of glial cells in schizophrenia and other related disorders
As we celebrate the 15th anniversary of Frontiers in Cellular Neuroscience, it is an opportune moment to reflect on the pi...
Editorial: Microglia in neurodegenerative diseases
Editorial: Microglia in neurodegenerative diseases
Neurodegenerative diseases are a heterogeneous group of disorders that share, among other characteristics, chronicity and ...
Dysregulated mTOR networks in experimental sporadic Alzheimer’s disease
Dysregulated mTOR networks in experimental sporadic Alzheimer’s disease
BackgroundBeyond the signature amyloid-beta plaques and neurofibrillary tangles, Alzheimer’s disease (AD) has been shown t...
Corrigendum: Contribution of thyrotropin-releasing hormone to cerebellar long-term depression and motor learning
Corrigendum: Contribution of thyrotropin-releasing hormone to cerebellar long-term depression and motor learning
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The gut-eye axis: the retinal/ocular degenerative diseases and the emergent therapeutic strategies
The interplay between human microbiota and various physiological systems has garnered significant attention in recent year...
Anti-neuroinflammatory effects of conjugated linoleic acid isomers, c9,t11 and t10,c12, on activated BV-2 microglial cells
Anti-neuroinflammatory effects of conjugated linoleic acid isomers, c9,t11 and t10,c12, on activated BV-2 microglial cells
Conjugated linoleic acid (CLA) isomers exhibit anti-inflammatory properties within the central nervous system (CNS). This ...
Anatomical and molecular development of the human primary visual cortex
Anatomical and molecular development of the human primary visual cortex
The human primary visual cortex (V1) development is pivotal to understanding cortical maturation and neuroplasticity. Theo...
Voltage-gated potassium channels as a potential therapeutic target for the treatment of neurological and psychiatric disorders
Voltage-gated potassium channels as a potential therapeutic target for the treatment of neurological and psychiatric disorders
Voltage-gated potassium channels are a widely distributed subgroup of potassium channels responsible for the efflux of pot...
Editorial: Neuromodulation technology: advances in optics and acoustics
It is estimated that about 43.3 million people are blind and 295 million with moderate to severe visual impairment worldwi...
Therapeutic potential of mesenchymal stem cell-derived exosomes and miRNAs in neuronal regeneration and rejuvenation in neurological disorders: a mini review
Therapeutic potential of mesenchymal stem cell-derived exosomes and miRNAs in neuronal regeneration and rejuvenation in neurological disorders: a mini review
Mesenchymal stem cells (MSCs) have gained considerable attention in the field of regenerative medicine due to their abilit...
Organoid intelligence for developmental neurotoxicity testing
Organoid intelligence for developmental neurotoxicity testing
The increasing prevalence of neurodevelopmental disorders has highlighted the need for improved testing methods to determi...
The impact of maternal anti-inflammatory drugs on surgical anesthesia-induced neuroinflammation and cognitive impairment in offspring mice
The impact of maternal anti-inflammatory drugs on surgical anesthesia-induced neuroinflammation and cognitive impairment in offspring mice
BackgroundThe impact of maternal surgery combined with general anesthesia on neuroinflammation and the development of lear...
Retraction: Santacruzamate A Ameliorates AD-Like Pathology by Enhancing ER Stress Tolerance Through Regulating the Functions of KDELR and Mia40-ALR in vivo and in vitro
Retraction: Santacruzamate A Ameliorates AD-Like Pathology by Enhancing ER Stress Tolerance Through Regulating the Functio...
Mathematical models of C-type and N-type inactivating heteromeric voltage gated potassium channels
Mathematical models of C-type and N-type inactivating heteromeric voltage gated potassium channels
Voltage gated potassium channels can be composed of either four identical, or different, pore-forming protein subunits. Wh...
Deprivation of visual input alters specific subset of inhibitory neurons and affect thalamic afferent terminals in V1 of rd1 mouse
Deprivation of visual input alters specific subset of inhibitory neurons and affect thalamic afferent terminals in V1 of rd1 mouse
Retinitis Pigmentosa (RP) is a heterogenous group of inherited disorder, and its progression not only affects the retina b...
Alzheimer’s disease induced neurons bearing PSEN1 mutations exhibit reduced excitability
Alzheimer’s disease induced neurons bearing PSEN1 mutations exhibit reduced excitability
Alzheimer’s disease (AD) is a devastating neurodegenerative condition that affects memory and cognition, characterized by ...
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