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Early physical rehabilitation dosage in the intensive care unit associates with hospital outcomes after critical COVID-19
Early physical rehabilitation dosage in the intensive care unit associates with hospital outcomes after critical COVID-19
To examine the relationship between physical rehabilitation parameters including an approach to quantifying dosage with ho...
Association between whole blood ratio and risk of mortality in massively transfused trauma patients: retrospective cohort study
Association between whole blood ratio and risk of mortality in massively transfused trauma patients: retrospective cohort study
Although whole blood (WB) transfusion was reported to improve survival in trauma patients with hemorrhagic shock, little i...
Hyperoxemia may be more beneficial for patients with sepsis
Hyperoxemia may be more beneficial for patients with sepsis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Plasma for prevention and treatment of glycocalyx degradation in trauma and sepsis
Plasma for prevention and treatment of glycocalyx degradation in trauma and sepsis
The endothelial glycocalyx, a gel-like layer that lines the luminal surface of blood vessels, is composed of proteoglycans...
Prioritising deteriorating patients using time-to-event analysis: prediction model development and internal–external validation
Prioritising deteriorating patients using time-to-event analysis: prediction model development and internal–external validation
Binary classification models are frequently used to predict clinical deterioration, however they ignore information on the...
Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study
Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study
In mechanically ventilated patients, diaphragm ultrasound can identify diaphragm weakness and predict weaning failure. We ...
Utility and rationale for continuous EEG monitoring: a primer for the general intensivist
Utility and rationale for continuous EEG monitoring: a primer for the general intensivist
This review offers a comprehensive guide for general intensivists on the utility of continuous EEG (cEEG) monitoring for c...
Clinical characteristics and outcomes of immunocompromised critically ill patients with cytomegalovirus end-organ disease: a multicenter retrospective cohort study
Clinical characteristics and outcomes of immunocompromised critically ill patients with cytomegalovirus end-organ disease: a multicenter retrospective cohort study
Cytomegalovirus (CMV) infection in patients with cellular immune deficiencies is associated with significant morbidity and...
Early bolus epinephrine administration during pediatric cardiopulmonary resuscitation for bradycardia with poor perfusion: an ICU-resuscitation study
Early bolus epinephrine administration during pediatric cardiopulmonary resuscitation for bradycardia with poor perfusion: an ICU-resuscitation study
Half of pediatric in-hospital cardiopulmonary resuscitation (CPR) events have an initial rhythm of non-pulseless bradycard...
Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes
Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes
Sepsis poses a grave threat, especially among children, but treatments are limited owing to heterogeneity among patients. ...
Gut-derived immune cells and the gut-lung axis in ARDS
Gut-derived immune cells and the gut-lung axis in ARDS
The gut serves as a vital immunological organ orchestrating immune responses and influencing distant mucosal sites, notabl...
Impact of the COVID-19 pandemic on lung-protective ventilation practice in critically ill patients with respiratory failure: a retrospective cohort study from a New England healthcare network
Impact of the COVID-19 pandemic on lung-protective ventilation practice in critically ill patients with respiratory failure: a retrospective cohort study from a New England healthcare network
To the Editor—Before the Coronavirus Disease 2019 (COVID-19) pandemic, over three million patients in the United States of...
Andexanet alpha versus four-factor prothrombin complex concentrate in DOACs anticoagulation reversal: an updated systematic review and meta-analysis
Andexanet alpha versus four-factor prothrombin complex concentrate in DOACs anticoagulation reversal: an updated systematic review and meta-analysis
There is currently a lack of evidence for the comparative effectiveness of Andexanet alpha and four-factor prothrombin com...
Is comorbidity alone responsible for changes in health-related quality of life among critical care survivors? A purpose-specific review
Is comorbidity alone responsible for changes in health-related quality of life among critical care survivors? A purpose-specific review
Health-related quality of life (HRQoL) is one of the most important outcome variables for assessing the effectiveness of i...
Sex differences in the SOFA score of ICU patients with sepsis or septic shock: a nationwide analysis
Sex differences in the SOFA score of ICU patients with sepsis or septic shock: a nationwide analysis
The Sequential Organ Failure Assessment (SOFA) score is an important tool in diagnosing sepsis and quantifying organ dysfu...
Gut colonization with multidrug resistant organisms in the intensive care unit: a systematic review and meta-analysis
Gut colonization with multidrug resistant organisms in the intensive care unit: a systematic review and meta-analysis
Gut colonization with multidrug-resistant organisms (MDRO) frequently precedes infection among patients in the intensive c...
Practical considerations on hypoxemia and hypoxia in V-V ECMO patients
Practical considerations on hypoxemia and hypoxia in V-V ECMO patients
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Potential bias and misclassification of using continuous cardiac output to identify fluid responsiveness compared to calibrated measurements
Potential bias and misclassification of using continuous cardiac output to identify fluid responsiveness compared to calibrated measurements
In this single-center observational study, we identified that 1/ CCO measured immediately before CO recalibration after a ...
Mechanical circulatory support in cardiogenic shock: microaxial flow pumps for all and VA-ECMO consigned to the museum?
Mechanical circulatory support in cardiogenic shock: microaxial flow pumps for all and VA-ECMO consigned to the museum?
Mortality rates in cardiogenic shock remain high, especially in patients with SCAI shock stages C to E [1]. When hemodynam...
Haemoglobin values, transfusion practices, and long-term outcomes in critically ill patients with traumatic brain injury: a secondary analysis of CENTER-TBI
Haemoglobin values, transfusion practices, and long-term outcomes in critically ill patients with traumatic brain injury: a secondary analysis of CENTER-TBI
Haemoglobin (Hb) thresholds and red blood cells (RBC) transfusion strategies in traumatic brain injury (TBI) are controver...
Can artificial intelligence help for scientific illustration? Details matter
Can artificial intelligence help for scientific illustration? Details matter
Rodriguez EE, Zaccarelli M, Sterchele ED, Taccone FS. “NeuroVanguard”: a contemporary strategy in neuromonitoring for seve...
Standard vs. carbone dioxide adapted kidney replacement therapy in hypercapnic ARDS patients: a randomized controlled pilot trial (BigBIC)
Standard vs. carbone dioxide adapted kidney replacement therapy in hypercapnic ARDS patients: a randomized controlled pilot trial (BigBIC)
Current continuous kidney replacement therapy (CKRT) protocols ignore physiological renal compensation for hypercapnia. Th...
Reliability and reproducibility of the venous excess ultrasound (VExUS) score, a multi-site prospective study: validating a novel ultrasound technique for comprehensive assessment of venous congestion
Reliability and reproducibility of the venous excess ultrasound (VExUS) score, a multi-site prospective study: validating a novel ultrasound technique for comprehensive assessment of venous congestion
Though the novel venous excess ultrasound (VExUS) score is increasingly used as a noninvasive means of venous congestion m...
Advanced waveform analysis of diaphragm surface EMG allows for continuous non-invasive assessment of respiratory effort in critically ill patients at different PEEP levels
Advanced waveform analysis of diaphragm surface EMG allows for continuous non-invasive assessment of respiratory effort in critically ill patients at different PEEP levels
Respiratory effort should be closely monitored in mechanically ventilated ICU patients to avoid both overassistance and un...
Sex differences in treatments and outcomes of patients with cardiogenic shock: a systematic review and epidemiological meta-analysis
Sex differences in treatments and outcomes of patients with cardiogenic shock: a systematic review and epidemiological meta-analysis
Women are at higher risk of mortality from many acute cardiovascular conditions, but studies have demonstrated differing f...
Comparative effectiveness of alternative spontaneous breathing trial techniques: a systematic review and network meta-analysis of randomized trials
Comparative effectiveness of alternative spontaneous breathing trial techniques: a systematic review and network meta-analysis of randomized trials
The spontaneous breathing trial (SBT) technique that best balance successful extubation with the risk for reintubation is ...
Development and external validation of a machine learning model for the prediction of persistent acute kidney injury stage 3 in multi-centric, multi-national intensive care cohorts
Development and external validation of a machine learning model for the prediction of persistent acute kidney injury stage 3 in multi-centric, multi-national intensive care cohorts
The aim of this retrospective cohort study was to develop and validate on multiple international datasets a real-time mach...
Sampling and processing matter in airway microbiota discovery
Sampling and processing matter in airway microbiota discovery
Ethics approval and consent to participate According to Fre...
Triggers of intensive care patients with palliative care needs from nurses’ perspective: a mixed methods study
Triggers of intensive care patients with palliative care needs from nurses’ perspective: a mixed methods study
Triggers have been developed internationally to identify intensive care patients with palliative care needs. Due to their ...
Biological basis of critical illness subclasses: from the bedside to the bench and back again
Biological basis of critical illness subclasses: from the bedside to the bench and back again
Critical illness syndromes including sepsis, acute respiratory distress syndrome, and acute kidney injury (AKI) are associ...
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