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Quantitative analysis of apparent diffusion coefficients to predict neurological prognosis in cardiac arrest survivors: an observational derivation and internal–external validation study
Quantitative analysis of apparent diffusion coefficients to predict neurological prognosis in cardiac arrest survivors: an observational derivation and internal–external validation study
This study aimed to validate apparent diffusion coefficient (ADC) values and thresholds to predict poor neurological outco...
Lower airway microbiota compositions differ between influenza, COVID-19 and bacteria-related acute respiratory distress syndromes
Lower airway microbiota compositions differ between influenza, COVID-19 and bacteria-related acute respiratory distress syndromes
Acute respiratory distress syndrome (ARDS) is responsible for 400,000 deaths annually worldwide. Few improvements have bee...
Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome
Respiratory drive heterogeneity associated with systemic inflammation and vascular permeability in acute respiratory distress syndrome
In acute respiratory distress syndrome (ARDS), respiratory drive often differs among patients with similar clinical charac...
Case study observational research: inflammatory cytokines in the bronchial epithelial lining fluid of COVID-19 patients with acute hypoxemic respiratory failure
Case study observational research: inflammatory cytokines in the bronchial epithelial lining fluid of COVID-19 patients with acute hypoxemic respiratory failure
In this study, the concentrations of inflammatory cytokines were measured in the bronchial epithelial lining fluid (ELF) a...
Rapidly improving ARDS differs clinically and biologically from persistent ARDS
Rapidly improving ARDS differs clinically and biologically from persistent ARDS
Rapidly improving acute respiratory distress syndrome (RIARDS) is an increasingly appreciated subgroup of ARDS in which hy...
Significance of critical closing pressures (starling resistors) in arterial circulation
Significance of critical closing pressures (starling resistors) in arterial circulation
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Ventilator-associated pneumonia related to extended-spectrum beta-lactamase producing Enterobacterales during severe acute respiratory syndrome coronavirus 2 infection: risk factors and prognosis
Ventilator-associated pneumonia related to extended-spectrum beta-lactamase producing Enterobacterales during severe acute respiratory syndrome coronavirus 2 infection: risk factors and prognosis
Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-COV 2) and requiring mechanical ventilati...
ACE inhibitors and angiotensin receptor blockers differentially alter the response to angiotensin II treatment in vasodilatory shock
ACE inhibitors and angiotensin receptor blockers differentially alter the response to angiotensin II treatment in vasodilatory shock
Angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor blockers (ARB) medications are widely prescribed. ...
Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation and immediate invasive assessment in refractory out-of-hospital cardiac arrest: a long-term follow-up of the Prague OHCA trial
Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation and immediate invasive assessment in refractory out-of-hospital cardiac arrest: a long-term follow-up of the Prague OHCA trial
Randomized data evaluating the impact of the extracorporeal cardiopulmonary resuscitation (ECPR) approach on long-term cli...
Impact of attaining aggressive vs. conservative PK/PD target on the clinical efficacy of beta-lactams for the treatment of Gram-negative infections in the critically ill patients: a systematic review and meta-analysis
Impact of attaining aggressive vs. conservative PK/PD target on the clinical efficacy of beta-lactams for the treatment of Gram-negative infections in the critically ill patients: a systematic review and meta-analysis
To perform a systematic review with meta-analysis with the dual intent of assessing the impact of attaining aggressive vs....
Contribution of electrical impedance tomography to personalize positive end-expiratory pressure under ECCO2R
Contribution of electrical impedance tomography to personalize positive end-expiratory pressure under ECCO2R
Extracorporeal Carbon Dioxide Removal (ECCO2R) is used in acute respiratory distress syndrome (ARDS) patients to facilitat...
Smoking on the risk of acute respiratory distress syndrome: a systematic review and meta-analysis
Smoking on the risk of acute respiratory distress syndrome: a systematic review and meta-analysis
The relationship between smoking and the risk of acute respiratory distress syndrome (ARDS) has been recognized, but the c...
Job description and perception of clinical research personnel working in a network of French intensive care units
Job description and perception of clinical research personnel working in a network of French intensive care units
There is a lack of information about the organisation and management of clinical research personnel in Europe and of their...
Neo-epitope detection identifies extracellular matrix turnover in systemic inflammation and sepsis: an exploratory study
Neo-epitope detection identifies extracellular matrix turnover in systemic inflammation and sepsis: an exploratory study
Sepsis is associated with high morbidity and mortality, primarily due to systemic inflammation-induced tissue damage, resu...
Outcome prediction of cardiac arrest with automatically computed gray-white matter ratio on computed tomography images
Outcome prediction of cardiac arrest with automatically computed gray-white matter ratio on computed tomography images
This study aimed to develop an automated method to measure the gray-white matter ratio (GWR) from brain computed tomograph...
Plasma glial fibrillary acidic protein and tau: predictors of neurological outcome after cardiac arrest
Plasma glial fibrillary acidic protein and tau: predictors of neurological outcome after cardiac arrest
The purpose was to evaluate glial fibrillary acidic protein (GFAP) and total-tau in plasma as predictors of poor neurologi...
Characteristics, predictors and outcomes of new-onset QT prolongation in sepsis: a multicenter retrospective study
Characteristics, predictors and outcomes of new-onset QT prolongation in sepsis: a multicenter retrospective study
Sepsis-induced myocardial injury is a serious complication of sepsis. QT prolongation is a proarrhythmic state which refle...
Anti-inflammatory therapies are associated with delayed onset of anemia and reduction in transfusion requirements in critically ill patients: results from two studies
Anti-inflammatory therapies are associated with delayed onset of anemia and reduction in transfusion requirements in critically ill patients: results from two studies
Anemia is a hallmark of critical illness, which is largely inflammatory driven. We hypothesized that the use of anti-infla...
Volatile versus propofol sedation after cardiac valve surgery: a single-center prospective randomized controlled trial
Volatile versus propofol sedation after cardiac valve surgery: a single-center prospective randomized controlled trial
Optimal intensive care of patients undergoing valve surgery is a complex balancing act between sedation for monitoring and...
GFAP point-of-care measurement for prehospital diagnosis of intracranial hemorrhage in acute coma
GFAP point-of-care measurement for prehospital diagnosis of intracranial hemorrhage in acute coma
Prehospital triage and treatment of patients with acute coma is challenging for rescue services, as the underlying patholo...
“NeuroVanguard”: a contemporary strategy in neuromonitoring for severe adult brain injury patients
“NeuroVanguard”: a contemporary strategy in neuromonitoring for severe adult brain injury patients
Severe acute brain injuries, stemming from trauma, ischemia or hemorrhage, remain a significant global healthcare concern ...
Vitamin D metabolism in critically ill patients with acute kidney injury: a prospective observational study
Vitamin D metabolism in critically ill patients with acute kidney injury: a prospective observational study
Vitamin D deficiency in critically ill patients is associated with poor outcomes, and vitamin D supplementation is recomme...
Facial appearance associates with longitudinal multi-organ failure: an ICU cohort study
Facial appearance associates with longitudinal multi-organ failure: an ICU cohort study
Facial appearance, whether consciously or subconsciously assessed, may affect clinical assessment and treatment strategies...
Dyssynchronous diaphragm contractions impair diaphragm function in mechanically ventilated patients
Dyssynchronous diaphragm contractions impair diaphragm function in mechanically ventilated patients
Pre-clinical studies suggest that dyssynchronous diaphragm contractions during mechanical ventilation may cause acute diap...
The management of heart failure cardiogenic shock: an international RAND appropriateness panel
The management of heart failure cardiogenic shock: an international RAND appropriateness panel
Observational data suggest that the subset of patients with heart failure related CS (HF-CS) now predominate critical care...
Response to commentary “The importance of assessing left ventricular longitudinal function in presence of increased afterload”
Response to commentary “The importance of assessing left ventricular longitudinal function in presence of increased afterload”
Ethics approval and consent to participate This study was a...
Quality of life-related and non-quality of life-related issues in ICU survivors and non-ICU-treated controls: a multi-group exploratory factor analysis
Quality of life-related and non-quality of life-related issues in ICU survivors and non-ICU-treated controls: a multi-group exploratory factor analysis
Quality of life (QoL) is a key outcome measure in healthcare. However, the heterogeneity in its definitions presents chall...
Unraveling the role of HIF-1α in sepsis: from pathophysiology to potential therapeutics—a narrative review
Unraveling the role of HIF-1α in sepsis: from pathophysiology to potential therapeutics—a narrative review
Sepsis is characterized by organ dysfunction resulting from a dysregulated inflammatory response triggered by infection, i...
Hydrocortisone rapidly and significantly reduces the IL-6 level in blood and lungs of patients with COVID-19-related ARDS
Hydrocortisone rapidly and significantly reduces the IL-6 level in blood and lungs of patients with COVID-19-related ARDS
We acknowledge all health care coworkers involved in the ICU department at the Bretonneau Hospital, especially Aurelie Aub...
Vascular leak in sepsis: physiological basis and potential therapeutic advances
Vascular leak in sepsis: physiological basis and potential therapeutic advances
Sepsis is a life-threatening condition characterised by endothelial barrier dysfunction and impairment of normal microcirc...
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