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Three-year mortality of ICU survivors with sepsis, an infection or an inflammatory illness: an individually matched cohort study of ICU patients in the Netherlands from 2007 to 2019
Three-year mortality of ICU survivors with sepsis, an infection or an inflammatory illness: an individually matched cohort study of ICU patients in the Netherlands from 2007 to 2019
Sepsis is a frequent reason for ICU admission and a leading cause of death. Its incidence has been increasing over the pas...
The effects between andexanet alpha and four-factor prothrombin complex concentrate on DOACs anticoagulation reversal
The effects between andexanet alpha and four-factor prothrombin complex concentrate on DOACs anticoagulation reversal
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
How to define parenteral nutrition
How to define parenteral nutrition
Department of Anaesthesiology and Intensive Care, Institute of Clinical Medicine, University of Tartu, Tartu, EstoniaAnnik...
Pitfall of lung ultrasound in the quantification of pneumothorax
Pitfall of lung ultrasound in the quantification of pneumothorax
We read with interest the article by Michael Beshara et al. [1] entitled “Nuts and bolts of lung ultrasound: utility, scan...
The long-term conditional mortality rate in older ICU patients compared to the general population
The long-term conditional mortality rate in older ICU patients compared to the general population
Understanding how preexisting comorbidities may interact with a critical illness is important for the assessment of long-t...
Predictors of weaning failure in ventilated intensive care patients: a systematic evidence map
Predictors of weaning failure in ventilated intensive care patients: a systematic evidence map
Ventilator weaning is of great importance for intensive care patients in order to avoid complications caused by prolonged ...
Impact of fever on the outcome non-anoxic acute brain injury patients: a systematic review and meta-analysis
Impact of fever on the outcome non-anoxic acute brain injury patients: a systematic review and meta-analysis
Fever is a common condition in intensive care unit (ICU) patients, with an incidence between 30 and 50% in non-neurologica...
Epidemiology of β-blocker use among critically iII patients during and after septic shock
Epidemiology of β-blocker use among critically iII patients during and after septic shock
Of 22,208 patients, 3748 were hospitalized with septic shock and received chronic β-blockers (mean age 67 ± 14 years, 56% ...
Representation of intensivists’ race/ethnicity, sex, and age by artificial intelligence: a cross-sectional study of two text-to-image models
Representation of intensivists’ race/ethnicity, sex, and age by artificial intelligence: a cross-sectional study of two text-to-image models
Integrating artificial intelligence (AI) into intensive care practices can enhance patient care by providing real-time pre...
Factors of prolonged-grief-disorder symptom trajectories for ICU bereaved family surrogates
Factors of prolonged-grief-disorder symptom trajectories for ICU bereaved family surrogates
Bereaved people experience distinct trajectories of prolonged-grief-disorder (PGD) symptoms. A few studies from outside cr...
Based -evidence, an intervention study to improve sleep quality in awake adult ICU patients: a prospective, single-blind, clustered controlled trial
Based -evidence, an intervention study to improve sleep quality in awake adult ICU patients: a prospective, single-blind, clustered controlled trial
Evidence-based guidelines advocate promoting sleep in intensive care unit (ICU) patients, yet many patients experience poo...
The efficacy of fiber-supplemented enteral nutrition in critically ill patients: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis
The efficacy of fiber-supplemented enteral nutrition in critically ill patients: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis
Evidence on the benefits of fiber-supplemented enteral nutrition (EN) in critically ill patients is inconsistent, and crit...
Changes in central venous-to-arterial PCO2 difference and central venous oxygen saturation as markers to define fluid responsiveness in critically ill patients: a pot-hoc analysis of a multi-center prospective study
Changes in central venous-to-arterial PCO2 difference and central venous oxygen saturation as markers to define fluid responsiveness in critically ill patients: a pot-hoc analysis of a multi-center prospective study
The main aim of the study whether changes in central venous-to-arterial CO2 difference (ΔP(v–a)CO2) and central...
Pressure support, patient effort and tidal volume: a conceptual model for a non linear interaction
Pressure support, patient effort and tidal volume: a conceptual model for a non linear interaction
Pressure support ventilation (PSV) is a form of assisted ventilation which has become frequently used, with the aim of par...
What every intensivist needs to know about mpox
What every intensivist needs to know about mpox
Supportive careFor most mild mpox patients with intact immune systems and no skin lesions, supportive care will help them ...
Transpulmonary pressure monitoring in critically ill patients: pros and cons—correction of description of the non-invasive PEEP-step method for separation of lung and chest wall mechanics
Transpulmonary pressure monitoring in critically ill patients: pros and cons—correction of description of the non-invasive PEEP-step method for separation of lung and chest wall mechanics
Background physiologyThe PEEP step method (PSM) is a non-invasive, esophageal pressure free method for separation of lung ...
Biochemical analysis of soft tissue infectious fluids and its diagnostic value in necrotizing soft tissue infections: a 5-year cohort study
Biochemical analysis of soft tissue infectious fluids and its diagnostic value in necrotizing soft tissue infections: a 5-year cohort study
Necrotizing soft tissue infections (NSTI) are rapidly progressing and life-threatening conditions that require prompt diag...
Development and functional characterization of a novel respiratory mask with full accordion cushioning to prevent air leaks and pressure injuries during non-invasive ventilation
Development and functional characterization of a novel respiratory mask with full accordion cushioning to prevent air leaks and pressure injuries during non-invasive ventilation
Non-invasive ventilation (NIV) is critical in the treatment of several respiratory diseases [1, 2]. However, interface air...
Interpretable machine learning model for new-onset atrial fibrillation prediction in critically ill patients: a multi-center study
Interpretable machine learning model for new-onset atrial fibrillation prediction in critically ill patients: a multi-center study
New-onset atrial fibrillation (NOAF) is the most common arrhythmia in critically ill patients admitted to intensive care a...
Effect of therapeutic plasma exchange on tissue factor and tissue factor pathway inhibitor in septic shock
Effect of therapeutic plasma exchange on tissue factor and tissue factor pathway inhibitor in septic shock
Coagulopathy is part of the pathological host response to infection in sepsis. Higher plasma concentrations of both tissue...
Airway epithelium damage in acute respiratory distress syndrome
Airway epithelium damage in acute respiratory distress syndrome
The airway epithelium (AE) fulfils multiple functions to maintain pulmonary homeostasis, among which ensuring adequate bar...
A narrative review on lung injury: mechanisms, biomarkers, and monitoring
A narrative review on lung injury: mechanisms, biomarkers, and monitoring
Lung injury is closely associated with the heterogeneity, severity, mortality, and prognosis of various respiratory diseas...
Sex differences in extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: nationwide multicenter retrospective study in Japan
Sex differences in extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: nationwide multicenter retrospective study in Japan
Previous studies examining sex differences in patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) for ...
Impact of low dose inhaled nitric oxide treatment in spontaneously breathing and intubated COVID-19 patients: a retrospective propensity-matched study
Impact of low dose inhaled nitric oxide treatment in spontaneously breathing and intubated COVID-19 patients: a retrospective propensity-matched study
The benefit of Inhaled nitric oxide (iNO) therapy in the setting of COVID-19-related ARDS is obscure. We performed a multi...
Self-confidence as a mediator in the relationship between executive functioning and depression among ICU survivors: a latent variable analysis
Self-confidence as a mediator in the relationship between executive functioning and depression among ICU survivors: a latent variable analysis
Executive dysfunction and depression are common among ICU survivors, yet the mechanisms linking these two factors remain p...
A plea for enhanced monitoring of depth of sedation in patients who are intubated and ventilated
A plea for enhanced monitoring of depth of sedation in patients who are intubated and ventilated
While adjusting sedative dosages seems logical, it can be challenging in critically ill, paralyzed patients. Hemodynamic v...
Identification of novel sub-phenotypes of severe ARDS requiring ECMO using latent class analysis
Identification of novel sub-phenotypes of severe ARDS requiring ECMO using latent class analysis
Sub-phenotyping of acute respiratory distress syndrome (ARDS) could be useful for evaluating the severity of ARDS or predi...
An update on the mechanical versus manual cardiopulmonary resuscitation in cardiac arrest patients
An update on the mechanical versus manual cardiopulmonary resuscitation in cardiac arrest patients
The cardiopulmonary resuscitation (CPR) technique and its outcome remains a debate. In response to Zhao et al.'s [1] regar...
Comparison of electrical impedance tomography, blood gas analysis, and respiratory mechanics for positive end-expiratory pressure titration
Comparison of electrical impedance tomography, blood gas analysis, and respiratory mechanics for positive end-expiratory pressure titration
The experiment protocol was approved by the Animal Care Committee of Fujian Provincial Hospital. The animals were treated ...
Incidence, predictability, and outcomes of systemic venous congestion following a fluid challenge in initially fluid-tolerant preload-responders after cardiac surgery: a pilot trial
Incidence, predictability, and outcomes of systemic venous congestion following a fluid challenge in initially fluid-tolerant preload-responders after cardiac surgery: a pilot trial
Fluid administration has traditionally focused on preload responsiveness (PR). However, preventing fluid intolerance, part...
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