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PCYT1A deficiency disturbs fatty acid metabolism and induces ferroptosis in the mouse retina
PCYT1A deficiency disturbs fatty acid metabolism and induces ferroptosis in the mouse retina
Inherited retinal dystrophies (IRDs) are a group of debilitating visual disorders characterized by the progressive degener...
A novel single-cell model reveals ferroptosis-associated biomarkers for individualized therapy and prognostic prediction in hepatocellular carcinoma
A novel single-cell model reveals ferroptosis-associated biomarkers for individualized therapy and prognostic prediction in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a prevalent malignancy with a pressing need for improved therapeutic response and progno...
ARID1A loss promotes RNA editing of CDK13 in an ADAR1-dependent manner
ARID1A loss promotes RNA editing of CDK13 in an ADAR1-dependent manner
ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, is thought to play a significant role both in tumor suppres...
3D exploration of gene expression in chicken embryos through combined RNA fluorescence in situ hybridization, immunofluorescence, and clearing
3D exploration of gene expression in chicken embryos through combined RNA fluorescence in situ hybridization, immunofluorescence, and clearing
Fine characterization of gene expression patterns is crucial to understand many aspects of embryonic development. The chic...
A hybrid TIM complex mediates protein import into hydrogenosomes of Trichomonas vaginalis
A hybrid TIM complex mediates protein import into hydrogenosomes of Trichomonas vaginalis
Hydrogenosomes are a specific type of mitochondria that have adapted for life under anaerobiosis. Limited availability of ...
Extensive remodeling of sugar metabolism through gene loss and horizontal gene transfer in a eukaryotic lineage
Extensive remodeling of sugar metabolism through gene loss and horizontal gene transfer in a eukaryotic lineage
In yeasts belonging to the subphylum Saccharomycotina, genes encoding components of the main metabolic pathways, like alco...
msBERT-Promoter: a multi-scale ensemble predictor based on BERT pre-trained model for the two-stage prediction of DNA promoters and their strengths
msBERT-Promoter: a multi-scale ensemble predictor based on BERT pre-trained model for the two-stage prediction of DNA promoters and their strengths
A promoter is a specific sequence in DNA that has transcriptional regulatory functions, playing a role in initiating gene ...
Asymmetry between the dorsal and ventral digging valves of the female locust: function and mechanics
Asymmetry between the dorsal and ventral digging valves of the female locust: function and mechanics
The female locust is equipped with unique digging tools, namely two pairs of valves—a dorsal and a ventral—uti...
Co-habiting ants and silverfish display a converging feeding ecology
Co-habiting ants and silverfish display a converging feeding ecology
Various animal taxa have specialized to living with social hosts. Depending on their level of specialization, these symbio...
Regulatory and evolutionary impact of DNA methylation in two songbird species and their naturally occurring F1 hybrids
Regulatory and evolutionary impact of DNA methylation in two songbird species and their naturally occurring F1 hybrids
Regulation of transcription by DNA methylation in 5’-CpG-3’ context is a widespread mechanism allowing differe...
The protein phosphatase PP6 promotes RIPK1-dependent PANoptosis
The protein phosphatase PP6 promotes RIPK1-dependent PANoptosis
The innate immune system serves as the first line of host defense. Transforming growth factor-β–activated kinas...
Deep behavioural phenotyping of the Q175 Huntington disease mouse model: effects of age, sex, and weight
Deep behavioural phenotyping of the Q175 Huntington disease mouse model: effects of age, sex, and weight
Huntington disease (HD) is a neurodegenerative disorder with complex motor and behavioural manifestations. The Q175 knock-...
Modality-specific effects of threat on self-motion perception
Modality-specific effects of threat on self-motion perception
Threat and individual differences in threat-processing bias perception of stimuli in the environment. Yet, their effect on...
Exonuclease editor promotes precision of gene editing in mammalian cells
Exonuclease editor promotes precision of gene editing in mammalian cells
Many efforts have been made to improve the precision of Cas9-mediated gene editing through increasing knock-in efficiency ...
Insights into the biocontrol and plant growth promotion functions of Bacillus altitudinis strain KRS010 against Verticillium dahliae
Insights into the biocontrol and plant growth promotion functions of Bacillus altitudinis strain KRS010 against Verticillium dahliae
Verticillium wilt, caused by the fungus Verticillium dahliae, is a soil-borne vascular fungal disease, which has caused gr...
Spatio-temporal characterization of phenotypic resistance in malaria vector species
Spatio-temporal characterization of phenotypic resistance in malaria vector species
Malaria, a deadly disease caused by Plasmodium protozoa parasite and transmitted through bites of infected female Anophele...
Dissecting thrombus-directed chemotaxis and random movement in neutrophil near-thrombus motion in flow chambers
Dissecting thrombus-directed chemotaxis and random movement in neutrophil near-thrombus motion in flow chambers
Thromboinflammation is caused by mutual activation of platelets and neutrophils. The site of thromboinflammation is determ...
Drought response revealed by chromatin organization variation and transcriptional regulation in cotton
Drought response revealed by chromatin organization variation and transcriptional regulation in cotton
Cotton is a major world cash crop and an important source of natural fiber, oil, and protein. Drought stress is becoming a...
Dynamics and drivers of fungal communities in a multipartite ant-plant association
Dynamics and drivers of fungal communities in a multipartite ant-plant association
Fungi and ants belong to the most important organisms in terrestrial ecosystems on Earth. In nutrient-poor niches of tropi...
The crotonylated and succinylated proteins of jujube involved in phytoplasma-stress responses
The crotonylated and succinylated proteins of jujube involved in phytoplasma-stress responses
Protein posttranslational modifications (PTMs) are fast and early responses to environmental changes, including pathogen i...
Cyp6g2 is the major P450 epoxidase responsible for juvenile hormone biosynthesis in Drosophila melanogaster
Cyp6g2 is the major P450 epoxidase responsible for juvenile hormone biosynthesis in Drosophila melanogaster
Juvenile hormones (JH) play crucial role in regulating development and reproduction in insects. The most common form of JH...
Evolutionary genomics of socially polymorphic populations of Pogonomyrmex californicus
Evolutionary genomics of socially polymorphic populations of Pogonomyrmex californicus
Social insects vary considerably in their social organization both between and within species. In the California harvester...
Comparative transcriptomic analysis provides insights into the genetic networks regulating oil differential production in oil crops
Comparative transcriptomic analysis provides insights into the genetic networks regulating oil differential production in oil crops
Plants differ more than threefold in seed oil contents (SOCs). Soybean (Glycine max), cotton (Gossypium hirsutum), rapesee...
Genomic insights into the cellular specialization of predation in raptorial protists
Genomic insights into the cellular specialization of predation in raptorial protists
Predation is a fundamental mechanism for organisms to acquire energy, and various species have evolved diverse tools to en...
Functional analysis of the mating type genes in Verticillium dahliae
Functional analysis of the mating type genes in Verticillium dahliae
Populations of the plant pathogenic fungus Verticillium dahliae display a complex and rich genetic diversity, yet the exis...
Temporal landscape and translational regulation of A-to-I RNA editing in mouse retina development
Temporal landscape and translational regulation of A-to-I RNA editing in mouse retina development
The significance of A-to-I RNA editing in nervous system development is widely recognized; however, its influence on retin...
Swd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6
Swd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6
Histone H3K4 tri-methylation (H3K4me3) catalyzed by Set1/COMPASS, is a prominent epigenetic mark found in promoter-proxima...
Comparative genomics of Ascetosporea gives new insight into the evolutionary basis for animal parasitism in Rhizaria
Comparative genomics of Ascetosporea gives new insight into the evolutionary basis for animal parasitism in Rhizaria
Ascetosporea (Endomyxa, Rhizaria) is a group of unicellular parasites infecting aquatic invertebrates. They are increasing...