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Single-cell RNA sequencing reveals the mediatory role of cancer-associated fibroblast PTN in hepatitis B virus cirrhosis-HCC progression
Cancer-associated fibroblasts (CAFs) are essential stromal components in the tumor microenvironment of hepatocellular carc...
Management of dyspepsia and Helicobacter pylori infection: the 2022 Indonesian Consensus Report
Dyspepsia still becomes a major challenge in upper gastrointestinal disease in Indonesia. This disease often correlated wi...
Therapeutic and prophylactic effects of oral administration of probiotic Enterococcus faecium Smr18 in Salmonella enterica-infected mice
Salmonella enterica serotype Typhi causes chronic enteric fever known as typhoid. Prolonged treatment regimen used for the...
Diversity and composition of gut microbiota in healthy individuals and patients at different stages of hepatitis B virus-related liver disease
Hepatitis B virus (HBV) causes chronic hepatitis B (CHB), liver cirrhosis, and hepatocellular carcinoma. The evolution of ...
Emerging applications of phage therapy and fecal virome transplantation for treatment of Clostridioides difficile infection: challenges and perspectives
Clostridioides difficile, which causes life-threatening diarrheal disease, is considered an urgent threat to healthcare se...
Association of gut microbial dysbiosis with disease severity, response to therapy and disease outcomes in Indian patients with COVID-19
Severe coronavirus disease 2019 (COVID-19) is associated with systemic hyper-inflammation. An adaptive interaction between...
Emerging role of bacterial outer membrane vesicle in gastrointestinal tract
Bacteria form a highly complex ecosystem in the gastrointestinal (GI) tract. In recent years, mounting evidence has shown ...
Butyrate driven raft disruption trots off enteric pathogen invasion: possible mechanism of colonization resistance
The gut microbiome derived short chain fatty acids perform multitude of functions to maintain gut homeostasis. Here we stu...
Intravenous antibiotics in preterm infants have a negative effect upon microbiome development throughout preterm life
Intestinal dysbiosis is implicated in the origins of necrotising enterocolitis and late-onset sepsis in preterm babies. Ho...
Vibrio cholerae O1 associated with recent endemic cholera shows temporal changes in serotype, genotype, and drug-resistance patterns in Bangladesh
Despite the advancement in our understanding of cholera and its etiological agent, Vibrio cholerae, the prevention and tre...
Detection of Virulence and β-lactamase resistance genes of non-typhoidal Salmonella isolates from human and animal origin in Egypt "one health concern"
Non-typhoidal Salmonella (NTS) is a major foodborne zoonotic pathogen worldwide. In the current study, Various NTS strains...
Gut microbiota and host cytochrome P450 characteristics in the pseudo germ-free model: co-contributors to a diverse metabolic landscape
The pseudo germ-free (PGF) model has been widely used to research the role of intestinal microbiota in drug metabolism and...
Modulation of duodenal and jejunal microbiota by rifaximin in mice with CCl4-induced liver fibrosis
Rifaximin is a poorly absorbed broad-spectrum antibiotic used for hepatic encephalopathy. Although increased Lactobacillac...
Gut colonization with vancomicyn-resistant enterococci among patients with hematologic malignancies
Vancomycin-resistant enterococci (VRE) are well known agents that colonize the gastrointestinal tract of immunocompromised...
Potential antiviral activities of chrysin against hepatitis B virus
Interferon and nucleos(t)ide analogues are current therapeutic treatments for chronic Hepatitis B virus (HBV) infection wi...
The benefit of the bismuth add-on to the 2-week clarithromycin-based triple regimen for Helicobacter pylori eradication: a propensity score-matched retrospective study
Bismuth salt is bacteriostatic and bactericidal against Helicobacter pylori (H. pylori). Little is known...
Comparison of antimicrobial resistant Escherichia coli isolated from Irish commercial pig farms with and without zinc oxide and antimicrobial usage
The prophylactic use of antimicrobials and zinc oxide (ZnO) in pig production was prohibited by the European Unio...
In-silico computational approaches to study microbiota impacts on diseases and pharmacotherapy
Microorganisms have been linked to a variety of critical human disease, thanks to advances in sequencing technology and mi...
CMTM3 protects the gastric epithelial cells from apoptosis and promotes IL-8 by stabilizing NEMO during Helicobacter pylori infection
CKLF-like MARVEL transmembrane domain containing 3 (CMTM3) plays an important role in cancer development. Although Helicob...
Campylobacter concisus from chronic inflammatory bowel diseases stimulates IL-8 production in HT-29 cells
The emerging pathogen Campylobacter concisus has been isolated from patients with gastrointestinal diseases; however, it i...
Invasion of intestinal cells by Staphylococcus warneri, a member of the human gut microbiota
Coagulase negative staphylococci (CoNS) are a heterogeneous group of bacteria that colonize different types of human epith...
Development of the gut microbiota during early life in premature and term infants
The gastrointestinal (GI) microbiota has been linked to health consequences throughout life, from early life illnesses (e....
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis
Paediatric pneumonia is a respiratory infection that affects infants and young children under the age of 3. This disease i...
Study of microencapsulated fatty acid antimicrobial activity in vitro and its prevention ability of Clostridium perfringens induced necrotic enteritis in broiler chicken
Necrotic enteritis (NE) is an infectious intestinal disease caused by Clostridium perfringens (C. perfringens) that is now...
Prevalence of pks + bacteria and enterotoxigenic Bacteroides fragilis in patients with colorectal cancer
Colorectal cancer (CRC) is the third most diagnosed cancer and the second most common cause of cancer deaths worldwide. CR...
Using whole-genome sequencing (WGS) to plot colorectal cancer-related gut microbiota in a population with varied geography
Colorectal cancer (CRC) is a multifactorial disease with genetic and environmental factors. Regional differences in risk f...
Dietary and lifestyle associations with microbiome diversity
Microbial dysbiosis has been closely linked with colorectal cancer development. However, data is limited regarding the rel...
Metagenomic analysis of the interaction between the gut microbiota and colorectal cancer: a paired-sample study based on the GMrepo database
Previous evidence has shown that the gut microbiota plays a role in the development and progression of colorectal cancer (...
Effect of proton pump inhibitors in infants with esophageal atresia on the gut microbiome: a pilot cohort
The effects of proton-pump inhibitors (PPIs) on the infant microbiome remain unclear. Swedish pilot cohort study to assess...
Gut microbiota in the early stage of Crohn’s disease has unique characteristics
Emerging evidence suggests that gut microbiota plays a predominant role in Crohn’s disease (CD). However, the microb...
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