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Corticosteroids: Giving and taking away
Corticosteroids: Giving and taking away
In Dickensian terms, corticosteroids are the best of drugs and the worst of drugs. As I often tell patients, we will both ...
In Reply: When should we consider SGLT-2 inhibitors in patients with acute decompensated heart failure?
In Reply: When should we consider SGLT-2 inhibitors in patients with acute decompensated heart failure?
We thank Dr. Sharma for the valuable contribution and concur with the opinion about optimal timing of initiating SGLT-2 in...
Acquired reactive perforating collagenosis in a patient with diabetes
Acquired reactive perforating collagenosis in a patient with diabetes
A 47-year-old woman presented with a 2-month history of pruritic eruptions on the left ankle and a complaint of thirst and...
Microscopic colitis: What is it, and what are the treatment options?
Microscopic colitis: What is it, and what are the treatment options?
Microscopic colitis, an inflammatory disorder characterized by chronic diarrhea, is so named because its diagnosis require...
Severe hyponatremia: Are you monitoring the urine output?
Severe hyponatremia: Are you monitoring the urine output?
A 52-year-old woman was brought to the emergency department by her friend because she was concerned about the woman’s new ...
When should I give corticosteroids to my patient with Pneumocystis pneumonia?
When should I give corticosteroids to my patient with Pneumocystis pneumonia?
Nonpregnant adult patients with human immunodeficiency virus (HIV) and Pneumocystis jirovecii (formerly carinii) pneumonia...
Nonhormone therapies for vasomotor symptom management
Nonhormone therapies for vasomotor symptom management
Vasomotor symptoms (VMS), more commonly known as hot flushes or flashes and night sweats, are the cardinal symptoms of men...
Management of lower-extremity venous thromboembolism: An updated review
Management of lower-extremity venous thromboembolism: An updated review
ABSTRACTAccording to the 2021 updated guidelines of the American College of Chest Physicians, the location of venous throm...
Glucocorticoid-induced adrenal insufficiency and glucocorticoid withdrawal syndrome: Two sides of the same coin
Glucocorticoid-induced adrenal insufficiency and glucocorticoid withdrawal syndrome: Two sides of the same coin
ABSTRACTDiseases of the adrenal glands can lead to primary adrenal insufficiency, and suppression of the hypothalamic-pitu...
A tale of scale: Corticosteroids and pustular psoriasis
A tale of scale: Corticosteroids and pustular psoriasis
In this issue of the Journal, Wong and colleagues1 describe a severe episode of generalized pustular psoriasis (GPP) in a ...
In Reply: 2023 Update in ambulatory general internal medicine
In Reply: 2023 Update in ambulatory general internal medicine
We appreciate Ashley Lim’s close read of our review. Regarding the use of SGLT-2 inhibitors in patients without albuminuri...
Steroid use triggers severe psoriatic reaction
Steroid use triggers severe psoriatic reaction
A 69-year-old man with well-controlled plaque psoriasis who presented to the emergency department for unilateral wrist pai...
Is there a role for chronic suppressive therapy in herpes simplex virus infection?
Is there a role for chronic suppressive therapy in herpes simplex virus infection?
Yes. The primary role of chronic suppressive therapy in herpes simplex virus (HSV) infection is to decrease the frequency,...
Medical management of benign prostatic hyperplasia
Medical management of benign prostatic hyperplasia
ABSTRACTMedical management of benign prostatic hyperplasia (BPH) has progressed gradually in recent years and remains the ...
Multiple metabolic renal manifestations of a systemic disease
Multiple metabolic renal manifestations of a systemic disease
A 39-year-old woman with a history of depression, anxiety, and recurrent nephrolithiasis with calcium phosphate and calciu...
Hematologic complications after kidney and pancreas transplant in a patient with chronic myeloid leukemia
Hematologic complications after kidney and pancreas transplant in a patient with chronic myeloid leukemia
A 35-year-old woman with a history of type 1 diabetes mellitus, diabetic retinopathy, and end-stage renal disease secondar...
Artificial intelligence in clinical practice: A look at ChatGPT
Artificial intelligence in clinical practice: A look at ChatGPT
In the rapidly evolving landscape of healthcare technologies, the integration of artificial intelligence in clinical pract...
Dealing with the "T" (testosterone)
Dealing with the "T" (testosterone)
Over the past few years, TV viewers have been inundated with commercials and infomercials extolling the value of testoster...
In Reply: Should I start an SGLT-2 inhibitor in my patient with heart failure and chronic kidney disease?
In Reply: Should I start an SGLT-2 inhibitor in my patient with heart failure and chronic kidney disease?
We thank Dr. Modarressi for his important and timely response. We agree with his recommendations for optimizing the utiliz...
Surgical and procedural management of benign prostatic hyperplasia
Surgical and procedural management of benign prostatic hyperplasia
To the Editor: We read with interest the recent article by Drs. Sotimehin, Haile, and Gill regarding the management of ben...
In Reply: Surgical and procedural management of benign prostatic hyperplasia
In Reply: Surgical and procedural management of benign prostatic hyperplasia
We appreciate the timely and helpful commentary by Dr. Gadani and colleagues highlighting the recent inclusion of PAE in t...
What are the management considerations for venous thromboembolic events in patients with cirrhosis?
What are the management considerations for venous thromboembolic events in patients with cirrhosis?
A 61-year-old man with Child-Pugh class A cirrhosis, admitted to the hospital with community-acquired pneumonia, is diagno...
Our Peer-Reviewers for 2023
Our Peer-Reviewers for 2023
We thank those who reviewed manuscripts submitted to the Cleveland Clinic Journal of Medicine in 2023. Reviewing papers fo...
Diagnosis and management of pancreatic cystic lesions for the non-gastroenterologist
Diagnosis and management of pancreatic cystic lesions for the non-gastroenterologist
ABSTRACTAlthough most pancreatic cystic lesions do not progress to cancer, they create concern for patients and their prim...
Does my patient have testosterone deficiency?
Does my patient have testosterone deficiency?
Diagnosis of testosterone deficiency (TD) requires the presence of relevant signs or symptoms along with biochemical evide...
Management of venous thromboembolism in patients with active cancer
Management of venous thromboembolism in patients with active cancer
ABSTRACTVenous thromboembolism (VTE) is a major health burden in patients with cancer, causing morbidity, emergency room v...
Hypertension and severe hyperreninemia in a young man
Hypertension and severe hyperreninemia in a young man
A 29-year-old man presented to the internal medicine clinic for evaluation of hypertension. His blood pressure at 2 separa...
von Willebrand disease: A guide for the internist
von Willebrand disease: A guide for the internist
ABSTRACTvon Willebrand disease (VWD), the most common inherited bleeding disorder, results when patients either do not mak...
Its a new year, looking back and looking forward
Its a new year, looking back and looking forward
2023 on the world stage was not exactly an uplifting Oscar winner. But within the microcosm of medicine, we have at least ...
Late complications after allogeneic hematopoietic cell transplant
Late complications after allogeneic hematopoietic cell transplant
I read with interest the excellent article by Granat et al1 on long-term management after allogeneic hematopoietic cell tr...
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