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Strategies of Perturbing Ion Homeostasis for Cancer Therapy
Strategies of Perturbing Ion Homeostasis for Cancer Therapy
Abstract Perturbing ion homeostasis has emerged as a novel therapeutic strategy for enhanced cancer therapy. Intensive dev...
Extending Drug Release from Implants via Transcutaneous Refilling with Solid Therapeutics
Extending Drug Release from Implants via Transcutaneous Refilling with Solid Therapeutics
Abstract Long-acting (LA) implantable drug delivery systems (IDDS) offer an effective approach for the management or preve...
Low Inorganic Phosphate Stress Inhibits Liver Cancer Progression: from In Vivo to In Vitro
Low Inorganic Phosphate Stress Inhibits Liver Cancer Progression: from In Vivo to In Vitro
Abstract Metabolic stress (for example, low pO2, low pH) stimulates cancer progression in a complex and largely unresolved...
Nanodelivery Systems Face Challenges and Limitations in Bone Diseases Management (Adv. Therap. 12/2021)
Nanodelivery Systems Face Challenges and Limitations in Bone Diseases Management (Adv. Therap. 12/2021)
In article number 2100152, the group of Taraballi Francesca summarize the current state of the art of nano-formulations fo...
Plasmon‐Enhanced Photocatalytic Activity of Organic Heterostructure for Indoor‐Light Antibacterial Therapy
Plasmon‐Enhanced Photocatalytic Activity of Organic Heterostructure for Indoor‐Light Antibacterial Therapy
Abstract Semiconductor nanomaterials with photocatalytic activity have been considered as potential antibacterial material...
Wavelength Independent Photo‐Chemo Tri‐Modal Combinatorial Renal Cell Carcinoma Therapy with Biocompatible Gold‐Titania Nanostars
Wavelength Independent Photo‐Chemo Tri‐Modal Combinatorial Renal Cell Carcinoma Therapy with Biocompatible Gold‐Titania Nanostars
Abstract Chemotherapy is the most commonly used strategy for the treatment of cancer; however, a complete cure is still co...
Future Directions for Ureteral Stent Technology: From Bench to the Market
Future Directions for Ureteral Stent Technology: From Bench to the Market
Abstract Ureteral stents are broadly used for the treatment of a wide range of pathologies, with different complexities an...
Recent Progress in Utilizing Upconversion Nanoparticles with Switchable Emission for Programmed Therapy
Recent Progress in Utilizing Upconversion Nanoparticles with Switchable Emission for Programmed Therapy
Abstract Conventional upconversion nanoparticles (UCNPs) based nanoplatforms have achieved significant progress in many fi...
Construction of Nanoscale Covalent Organic Frameworks via Photocatalysis‐Involved Cascade Reactions for Tumor‐Selective Treatment
Construction of Nanoscale Covalent Organic Frameworks via Photocatalysis‐Involved Cascade Reactions for Tumor‐Selective Treatment
Abstract Photocatalysis is a powerful tool in modern organic synthesis, however, it has not been applied to the synthesis ...
Recent Advances in Bio‐Compatible Oxygen Singlet Generation and Its Tumor Treatment
Recent Advances in Bio‐Compatible Oxygen Singlet Generation and Its Tumor Treatment
Abstract Light-dependent singlet oxygen (1O2) produced in photodynamic therapy (PDT), is a biologically compatible reactiv...
Microbubbles for Combination Tumor Treatment
Microbubbles for Combination Tumor Treatment
DOI: 10.1002/adtp.202100050 Adv. Therap. 2021, 4, 2100050 The authors are correcting...
Sonoporation‐Enhanced Delivery of STING Agonist Induced Robust Immune Modulation and Tumor Regression (Adv. Therap. 10/2021)
Sonoporation‐Enhanced Delivery of STING Agonist Induced Robust Immune Modulation and Tumor Regression (Adv. Therap. 10/2021)
In article number 2100154, Jun Xu, Adam Procopio, and co-workers have demonstrated a 5 min clinically translatable sonopor...
Nanodelivery Systems Face Challenges and Limitations in Bone Diseases Management
Nanodelivery Systems Face Challenges and Limitations in Bone Diseases Management
Abstract Bone is a highly dynamic tissue. Hence, diseases affecting bone tissue, such as cancer (primary tumors and metast...
Light‐Triggered Drug Release from Red Blood Cells Suppresses Arthritic Inflammation
Light‐Triggered Drug Release from Red Blood Cells Suppresses Arthritic Inflammation
Abstract Arthritis is a leading cause of disability in adults, which can be intensely incapacitating. The location and int...
Nanoparticle‐Mediated Delivery of Micheliolide Analogs to Eliminate Leukemic Stem Cells in the Bone Marrow
Nanoparticle‐Mediated Delivery of Micheliolide Analogs to Eliminate Leukemic Stem Cells in the Bone Marrow
Abstract Micheliolide (MCL) is a naturally occurring sesquiterpene lactone that selectively targets leukemic stem cells (L...
Recent Progress in Skin‐on‐a‐Chip Platforms
Recent Progress in Skin‐on‐a‐Chip Platforms
Abstract As the largest organ of the body, the skin acts as a physical barrier for preventing excessive water loss and inf...
T Cell‐Signaling‐Responsive Conjugate of Antibody with siRNA to Overcome Acquired Resistance to anti‐PD‐1 Immunotherapy
T Cell‐Signaling‐Responsive Conjugate of Antibody with siRNA to Overcome Acquired Resistance to anti‐PD‐1 Immunotherapy
Abstract Acquired resistance (AR) resulted from stimulated expression of AR-related genes such as CD38 in activated T cell...
Dimethylaminomicheliolide Sensitizes Cancer Cells to Radiotherapy for Synergistic Combination with Immune Checkpoint Blockade
Dimethylaminomicheliolide Sensitizes Cancer Cells to Radiotherapy for Synergistic Combination with Immune Checkpoint Blockade
Abstract Radiotherapy (RT) has demonstrated synergy with immune checkpoint blockade (ICB) in preclinical models. However, ...
Investigation of FcRn‐Mediated Transepithelial Mechanisms for Oral Nanoparticle Delivery Systems
Investigation of FcRn‐Mediated Transepithelial Mechanisms for Oral Nanoparticle Delivery Systems
Abstract Oral delivery is the most widely used modality for drug administration, but its efficiency is hampered by the lim...
Study on Significance of Receptor Targeting in Killing of Intracellular Bacteria with Membrane‐Impermeable Antibiotics
Study on Significance of Receptor Targeting in Killing of Intracellular Bacteria with Membrane‐Impermeable Antibiotics
Abstract Water-soluble antibiotics are largely excluded from therapy of intracellular infections, such as Shigella spp., L...
Optimization of Microbubble‐Based DNA Vaccination with Low‐Frequency Ultrasound for Enhanced Cancer Immunotherapy
Optimization of Microbubble‐Based DNA Vaccination with Low‐Frequency Ultrasound for Enhanced Cancer Immunotherapy
Abstract Immunotherapy is an important cancer treatment strategy; nevertheless, the lack of robust immune cell infiltratio...