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Viral vectors: design and delivery for small RNA
Viral vectors: design and delivery for small RNA
RNA interference regulates gene expression by selectively silencing target genes through the introduction of small RNA mol...
Preserving the antimicrobial arsenal: exploring alternatives to carbapenems in ESBL battles within the southeast of Ireland
Preserving the antimicrobial arsenal: exploring alternatives to carbapenems in ESBL battles within the southeast of Ireland
Introduction. Carbapenems are usually employed as first-line antimicrobials against bacteria harbouring extended-spectrum ...
Progress in the investigation of the Firmicutes/Bacteroidetes ratio as a potential pathogenic factor in ulcerative colitis
Progress in the investigation of the Firmicutes/Bacteroidetes ratio as a potential pathogenic factor in ulcerative colitis
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that presents significant challenges in terms of tre...
Ethnicity-matched case–control study reveals significant gut microbiota differences in Malaysian adults with type 2 diabetes
Ethnicity-matched case–control study reveals significant gut microbiota differences in Malaysian adults with type 2 diabetes
Introduction. Type 2 diabetes mellitus (T2DM) is a major global health issue projected to exceed 700 million cases by 2045...
Prospective evaluation of different faecal preservation media for travellers’ diarrhoea diagnostic application with multiplex PCR BioFire FilmArray in resource-limited settings
Prospective evaluation of different faecal preservation media for travellers’ diarrhoea diagnostic application with multiplex PCR BioFire FilmArray in resource-limited settings
Introduction. Immediate identification of travellers’ diarrhoea-causing pathogens may not be possible in remote settings, ...
Impact of dairy calf management practices on the intestinal tract microbiome pre-weaning
Impact of dairy calf management practices on the intestinal tract microbiome pre-weaning
Introduction. Microbiota in the gastrointestinal tract (GIT) consisting of the rumen and hindgut (the small intestine, cec...
Inactivation of Candida albicans, Staphylococcus aureus and multidrug-resistant Escherichia coli with dielectric barrier discharged cold atmospheric plasma: a comparative study with antimicrobial drugs
Inactivation of Candida albicans, Staphylococcus aureus and multidrug-resistant Escherichia coli with dielectric barrier discharged cold atmospheric plasma: a comparative study with antimicrobial drugs
Introduction. Cold atmospheric plasma (CAP) has emerged as a promising technology for neutralizing microbes, including mul...
Antifungal activity of 2-adamantylamine hydrochloride on Candida albicans and Candida parapsilosis
Antifungal activity of 2-adamantylamine hydrochloride on Candida albicans and Candida parapsilosis
Introduction. Increased virulence and drug resistance in species of Candida resulted in reduced disease control and furthe...
Low cluster of differentiation 4+ T-cell count associated with thrombocytopenia among people living with human immunodeficiency virus-1 receiving antiretroviral in West Papua
Low cluster of differentiation 4+ T-cell count associated with thrombocytopenia among people living with human immunodeficiency virus-1 receiving antiretroviral in West Papua
Introduction. Anaemia and thrombocytopenia are blood-related irregularities linked to an increased likelihood of disease p...
Prevalence, aetiology and antimicrobial resistance profile of diabetic individuals suffering from community-acquired urinary tract infection
Prevalence, aetiology and antimicrobial resistance profile of diabetic individuals suffering from community-acquired urinary tract infection
Introduction. The rise in antimicrobial resistance poses a significant threat to global health, particularly among diabeti...
Pathogenesis of Staphylococcus epidermidis prosthetic joint infections: bacterial adhesion and internalization in osteoblasts, synoviocytes and endothelial cells
Pathogenesis of Staphylococcus epidermidis prosthetic joint infections: bacterial adhesion and internalization in osteoblasts, synoviocytes and endothelial cells
Staphylococcus epidermidis is frequently isolated during prosthetic joint infections (PJIs). Unlike Staphylococcus aureus,...
Antifungal potential of silver nanoparticles stabilized with the flavonoid naringenin
Antifungal potential of silver nanoparticles stabilized with the flavonoid naringenin
Introduction. Fungal infections caused by yeast have increased in recent decades, becoming a major threat to public health...
Epidemiology of Shiga toxin-producing Escherichia coli other than serotype O157:H7 in England, 2016–2023
Epidemiology of Shiga toxin-producing Escherichia coli other than serotype O157:H7 in England, 2016–2023
Introduction. Shiga toxin-producing Escherichia coli (STEC) infections are of public health concern as STEC can cause larg...
Safety and efficacy of lamivudine/dolutegravir vs. bictegravir/emtricitabine/tenofovir alafenamide in antiretroviral-naive adults with HIV-1 infection in Shanghai, China: a single-centre retrospective study
Safety and efficacy of lamivudine/dolutegravir vs. bictegravir/emtricitabine/tenofovir alafenamide in antiretroviral-naive adults with HIV-1 infection in Shanghai, China: a single-centre retrospective study
Introduction. Lamivudine plus dolutegravir (3TC/DTG) and bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) regimen...
Modified multiplex PCR for serotyping and pathotyping of Streptococcus suis
Modified multiplex PCR for serotyping and pathotyping of Streptococcus suis
Introduction. Streptococcus suis is a zoonotic pathogen that causes invasive infections in humans who have been in close c...
Performance of metagenomic next-generation sequencing for microbiological diagnosis of infectious uveitis
Performance of metagenomic next-generation sequencing for microbiological diagnosis of infectious uveitis
Introduction. Diagnosis of uveitis is challenging due to the multitude of possible pathogenies. Identifying infectious and...
Comparison of the bacterial microbiome in the pharynx and nasal cavity of persistent, intermittent carriers and non-carriers of Staphylococcus aureus
Comparison of the bacterial microbiome in the pharynx and nasal cavity of persistent, intermittent carriers and non-carriers of Staphylococcus aureus
Introduction. Staphylococcus aureus is a bacterium that colonizes various human sites. The pharynx has been considered as ...
Susceptibility of Gram-negative bacteria from blood cultures assessed by a rapid antimicrobial susceptibility assay, the VITEK® Reveal™: a preliminary study
Susceptibility of Gram-negative bacteria from blood cultures assessed by a rapid antimicrobial susceptibility assay, the VITEK® Reveal™: a preliminary study
The timely administration of the effective therapy is an important factor for the favourable outcome of patients with seps...
Machine learning-driven in-hospital mortality prediction in HIV/AIDS patients with Cytomegalovirus infection: a single-centred retrospective study
Machine learning-driven in-hospital mortality prediction in HIV/AIDS patients with Cytomegalovirus infection: a single-centred retrospective study
Introduction. Cytomegalovirus (CMV) is a widely disseminated betaherpesvirus that typically induces latant infections. In ...
Dysbiosis–epigenetics–immune system interaction and ageing health problems
Dysbiosis–epigenetics–immune system interaction and ageing health problems
Background. The growing interest in microbiota–epigenetics–immune system research stems from the understanding that microb...
Knocking Out Antimicrobial Resistance editorial: reflections on the United Nations General Assembly high-level meeting on antimicrobial resistance
Knocking Out Antimicrobial Resistance editorial: reflections on the United Nations General Assembly high-level meeting on antimicrobial resistance
Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit pu...
Chronic Strongyloides stercoralis infection in Fijian migrants to the UK
Chronic Strongyloides stercoralis infection in Fijian migrants to the UK
Introduction. Strongyloides stercoralis, the human threadworm, is a parasitic nematode with global distribution, estimated...
Genotypic analysis of Shiga toxin-producing Escherichia coli clonal complex 17 in England and Wales, 2014–2022
Genotypic analysis of Shiga toxin-producing Escherichia coli clonal complex 17 in England and Wales, 2014–2022
Introduction. Shiga toxin-producing Escherichia coli (STEC) are zoonotic, gastrointestinal pathogens characterized by the ...
Antifungal resistance, clinical outcome and clinico-microbiological correlation in ocular infections due to common melanized fungi Curvularia lunata and Lasiodiplodia theobromae in South India
Antifungal resistance, clinical outcome and clinico-microbiological correlation in ocular infections due to common melanized fungi Curvularia lunata and Lasiodiplodia theobromae in South India
Aim. Melanized fungi were rarely studied for their antifungal resistance (AFR) or clinical outcome, despite rising inciden...
Mycoplasma pneumoniae: not a typical respiratory pathogen
Mycoplasma pneumoniae: not a typical respiratory pathogen
Mycoplasma pneumoniae is a leading cause of community-acquired pneumonia among school-aged children and young adults. Infe...
Evaluation of GeneXpert MTB/Rif Ultra assay performance on formalin-fixed paraffin-embedded tissues for Mycobacterium tuberculosis detection
Evaluation of GeneXpert MTB/Rif Ultra assay performance on formalin-fixed paraffin-embedded tissues for Mycobacterium tuberculosis detection
We evaluated the Xpert MTB/Rif Ultra assay performance for Mycobacterium tuberculosis (MTB) detection in formalin-fixed pa...
EDTA, aspirin and d-mannose inhibit the biofilm formation of Proteus vulgaris by hindering its adhesion to catheter devices: a proposed strategy for CAUTI prevention
EDTA, aspirin and d-mannose inhibit the biofilm formation of Proteus vulgaris by hindering its adhesion to catheter devices: a proposed strategy for CAUTI prevention
Introduction. Catheter-associated urinary tract infection (CAUTI) is a common nosocomial infection treated with antibiotic...
Tissue response in a rat model of denture stomatitis treated with tissue conditioner containing antifungal complexed with β-cyclodextrin
Tissue response in a rat model of denture stomatitis treated with tissue conditioner containing antifungal complexed with β-cyclodextrin
Introduction. Tissue conditioners modified with antifungals are a potential alternative to denture stomatitis (DS) treatme...
Absence of measurable quantities of Candida auris and Cryptococcus spp. in the gut microbiota of Ghanaian individuals with and without HIV infection as confirmed by applying multiple real-time PCR assays
Absence of measurable quantities of Candida auris and Cryptococcus spp. in the gut microbiota of Ghanaian individuals with and without HIV infection as confirmed by applying multiple real-time PCR assays
Introduction. Fungal infections are relevant health risks for individuals with acquired immunodeficiency in the resource-l...
Lower gastrointestinal tract dysbiosis in persistent critical illness: a systematic review
Lower gastrointestinal tract dysbiosis in persistent critical illness: a systematic review
Introduction. The human lower gastrointestinal tract microbiome is complex, dynamic and prone to disruption occurring duri...
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