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Artificial intelligence in bone marrow histological diagnostics: potential applications and challenges
Artificial intelligence in bone marrow histological diagnostics: potential applications and challenges
The expanding digitalization of routine diagnostic histological slides holds a potential to apply artificial intelligence ...
Guidelines for Handling of Cytological Specimens in Cancer Genomic Medicine
Guidelines for Handling of Cytological Specimens in Cancer Genomic Medicine
Rapid advances are being made in cancer drug therapy. Since molecularly targeted therapy has been introduced, personalized...
miR-142-3p Suppresses Invasion and Adhesion of Mesothelioma Cells by Downregulating ITGAV
miR-142-3p Suppresses Invasion and Adhesion of Mesothelioma Cells by Downregulating ITGAV
<b><i>Introduction:</i></b> Malignant mesothelioma is an aggressive cancer associated with asbesto...
Clinical Value of Platelets and Coagulation Parameters in Predicting the Severity of Delta Variant SARS-CoV-2
Clinical Value of Platelets and Coagulation Parameters in Predicting the Severity of Delta Variant SARS-CoV-2
<b><i>Introduction:</i></b> The present study aimed to analyze the clinical features and laborator...
Clinical and Prognostic Impact of the Warburg Effect in Esophageal Carcinoma: Monocarboxylate Transporters as Candidates for Therapeutic Targeting
Clinical and Prognostic Impact of the Warburg Effect in Esophageal Carcinoma: Monocarboxylate Transporters as Candidates for Therapeutic Targeting
<b><i>Introduction:</i></b> Esophageal cancer (EC) seems to display increased glycolytic activity,...
Blood Liquid Biopsy in an Advanced Medullary Thyroid Carcinoma: A Case Study with Rearranged during Transfection Heterogeneity
Blood Liquid Biopsy in an Advanced Medullary Thyroid Carcinoma: A Case Study with Rearranged during Transfection Heterogeneity
<b><i>Introduction:</i></b> Liquid biopsy is an innovative and efficient method for studying circu...
Cancer registration, molecular marker status and adherence to the WHO 2016 classification of pathology reports for glioma diagnosed during 2017-2019 in Belgium
Cancer registration, molecular marker status and adherence to the WHO 2016 classification of pathology reports for glioma diagnosed during 2017-2019 in Belgium
Introduction: The objective of this study is to cross-check and if necessary, adjust registered ICD-O-3 topography and mor...
Renal cell carcinoma in end-stage renal disease: A retrospective study in patients from Hungary
Renal cell carcinoma in end-stage renal disease: A retrospective study in patients from Hungary
Introduction: End-stage renal disease (ESRD) and acquired cystic kidney disease (ACKD) are known risk factors for renal ce...
GATA3 Expression in Human Tumors: A Tissue Microarray Study on 16,557 Tumors
GATA3 Expression in Human Tumors: A Tissue Microarray Study on 16,557 Tumors
<b><i>Introduction:</i></b> GATA3 is a transcription factor involved in epithelial cell differenti...
Evaluation of the Implementation and Diagnostic Accuracy of the Paris Classification for Reporting Urinary Cytology in Voided Urine Specimens: A Cyto-Histological Correlation Study in a Cancer Center
Evaluation of the Implementation and Diagnostic Accuracy of the Paris Classification for Reporting Urinary Cytology in Voided Urine Specimens: A Cyto-Histological Correlation Study in a Cancer Center
<b><i>Introduction:</i></b> The Paris classification highlights the need to focus on accurately i...
Contents, Vol. 89, 2022
Contents, Vol. 89, 2022
Pathobiology...
Flow Cytometry Analysis Reveals a Wide Cytologic and Immunophenotypic Spectrum of Peripheral B Lymphocytes in Angioimmunoblastic T-Cell Lymphoma
Flow Cytometry Analysis Reveals a Wide Cytologic and Immunophenotypic Spectrum of Peripheral B Lymphocytes in Angioimmunoblastic T-Cell Lymphoma
<b><i>Introduction:</i></b> Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive T-cell lymp...
Lymphocyte Subsets in Cervicovaginal Lavage Specimens of HIV-Infected Women: A Surrogate Risk Marker of HPV-Associated Cervical Lesions
Lymphocyte Subsets in Cervicovaginal Lavage Specimens of HIV-Infected Women: A Surrogate Risk Marker of HPV-Associated Cervical Lesions
<b><i>Introduction:</i></b> To better understand the role of mucosa immunity in the development of...
Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics
Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics
<b><i>Introduction:</i></b> Colorectal carcinoma (CRC) is among the most common carcinomas in wome...
Evolutionary Changes in Pathology and Our Understanding of Disease
Evolutionary Changes in Pathology and Our Understanding of Disease
The history of pathology involves human dissections, autopsies, microscopy, as well as the development of histopathologica...
A Comparison of Tissue Dissection Techniques for Diagnostic, Prognostic, and Theragnostic Analysis of Human Disease
A Comparison of Tissue Dissection Techniques for Diagnostic, Prognostic, and Theragnostic Analysis of Human Disease
Histopathology has historically been the critical technique for the diagnosis and treatment of human disease. Today, genom...
The More Extensive the Spread through Air Spaces, the Worse the Prognosis Is: Semi-Quantitative Evaluation of Spread through Air Spaces in Pulmonary Adenocarcinomas
The More Extensive the Spread through Air Spaces, the Worse the Prognosis Is: Semi-Quantitative Evaluation of Spread through Air Spaces in Pulmonary Adenocarcinomas
<b><i>Introduction:</i></b> The extent of spread through air spaces (STAS) is less investigated am...
Autoimmune Thyroiditis Induced by Bartonella henselae (Cat-Scratch Disease) Might Be Reversible
Autoimmune Thyroiditis Induced by Bartonella henselae (Cat-Scratch Disease) Might Be Reversible
<b><i>Introduction:</i></b> <i>Bartonella henselae</i> infection leads to development ...
Tissue Fixation with a Formic Acid-Deprived Formalin Better Preserves DNA Integrity over Time
Tissue Fixation with a Formic Acid-Deprived Formalin Better Preserves DNA Integrity over Time
<b><i>Introduction:</i></b> Optimization of pre-analytic procedures and tissue processing is a bas...
Myeloid Sarcoma of the Breast as Blast Phase of JAK2-Mutated (Val617Phe Exon 14p) Essential Thrombocythemia: A Case Report and a Systematic Literature Review
Myeloid Sarcoma of the Breast as Blast Phase of JAK2-Mutated (Val617Phe Exon 14p) Essential Thrombocythemia: A Case Report and a Systematic Literature Review
<b><i>Introduction:</i></b> Myeloid sarcoma (MS) is a mass-forming proliferation of myeloid blasts...
Minichromosome Maintenance 4 Is Associated with Cancer Stemness and Poor Survival of Patients with Gastric Cancer
Minichromosome Maintenance 4 Is Associated with Cancer Stemness and Poor Survival of Patients with Gastric Cancer
<b><i>Introduction:</i></b> Gastric cancer (GC) is a leading cause of cancer-related death worldwi...
Interstitial Pulmonary Fibrosis and Extensive Dendriform Ossification with Persistent Viral Load: A Rare Presentation of Post-COVID-19 Condition in Need of Lung Transplantation
Interstitial Pulmonary Fibrosis and Extensive Dendriform Ossification with Persistent Viral Load: A Rare Presentation of Post-COVID-19 Condition in Need of Lung Transplantation
The incidence, presentation, and predisposing factors of post-acute sequelae of COVID-19 (PASC) are currently poorly under...
Expression of MMP-2, MMP-7, MMP-9, and TIMP-1 by Inflamed Mucosa in the Initial Diagnosis of Ulcerative Colitis as a Response Marker for Conventional Medical Treatment
Expression of MMP-2, MMP-7, MMP-9, and TIMP-1 by Inflamed Mucosa in the Initial Diagnosis of Ulcerative Colitis as a Response Marker for Conventional Medical Treatment
<b><i>Introduction:</i></b> Experimental and clinical data involve matrix metalloproteases (MMPs) ...
PKCι Is a Promising Prognosis Biomarker and Therapeutic Target for Pancreatic Cancer
PKCι Is a Promising Prognosis Biomarker and Therapeutic Target for Pancreatic Cancer
<b><i>Background:</i></b> As the highest prevalent pancreatic cancer, pancreatic ductal adenocarci...
ANXA10 Expression Is Inversely Associated with Tumor Stage, Grade, and TP53 Expression in Upper and Lower Urothelial Carcinoma
ANXA10 Expression Is Inversely Associated with Tumor Stage, Grade, and TP53 Expression in Upper and Lower Urothelial Carcinoma
<b><i>Introduction:</i></b> Urothelial carcinoma (UC) is a common type of malignant disease, but l...
Assessment of Predictive Biomarkers in Breast Cancer: Challenges and Updates
Assessment of Predictive Biomarkers in Breast Cancer: Challenges and Updates
The management of patients with breast cancer (BC) relies on the assessment of a defined set of well-established prognosti...
Characterization of the Immune Microenvironment in Inflammatory Breast Cancer Using Multiplex Immunofluorescence
Characterization of the Immune Microenvironment in Inflammatory Breast Cancer Using Multiplex Immunofluorescence
<b><i>Introduction:</i></b> Inflammatory breast cancer (IBC) is an aggressive form of breast cance...
Essential Roles of TDO2 in Gastric Cancer: TDO2 Is Associated with Cancer Progression, Patient Survival, PD-L1 Expression, and Cancer Stem Cells
Essential Roles of TDO2 in Gastric Cancer: TDO2 Is Associated with Cancer Progression, Patient Survival, PD-L1 Expression, and Cancer Stem Cells
<b><i>Introduction:</i></b> Tryptophan metabolism has been shown to be involved in tumor developme...
DAXX, ATRX, and MSI in PanNET and Their Metastases: Correlation with Histopathological Data and Prognosis
DAXX, ATRX, and MSI in PanNET and Their Metastases: Correlation with Histopathological Data and Prognosis
<b><i>Introduction:</i></b> Studies on pancreatic neuroendocrine tumors (PanNETs) regarding loss o...
Sustained Inflammation of Breast Tumors after Needle Biopsy
Sustained Inflammation of Breast Tumors after Needle Biopsy
<b><i>Introduction:</i></b> Needle biopsy is essential for definitive diagnosis of breast malignan...
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