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High Inner Centromere Protein Expression Correlates with Aggressive Features and Predicts Poor Prognosis in Patients with Invasive Breast Cancer
High Inner Centromere Protein Expression Correlates with Aggressive Features and Predicts Poor Prognosis in Patients with Invasive Breast Cancer
<b><i>Introduction:</i></b> Inner centromere protein (<i>INCENP</i>) is a member of th...
NPM1-Mutated Acute Myeloid Leukemia: Recent Developments and Open Questions
NPM1-Mutated Acute Myeloid Leukemia: Recent Developments and Open Questions
Somatic mutations in the nucleophosmin (<i>NPM1</i>) gene occur in approximately 30% of de novo acute myeloid ...
Distribution and clinical significance of HPV16 variants in head and neck squamous cell carcinomas: data from a Portuguese cohort and systematic review
Distribution and clinical significance of HPV16 variants in head and neck squamous cell carcinomas: data from a Portuguese cohort and systematic review
Introduction: Genomic variants of the human papillomavirus type 16 (HPV16) are thought to play differential roles in the s...
Disruptive and truncating TP53 mutations are associated with African-ancestry and worse prognosis in Brazilian patients with lung adenocarcinoma
Disruptive and truncating TP53 mutations are associated with African-ancestry and worse prognosis in Brazilian patients with lung adenocarcinoma
INTRODUCTION: TP53 is the most frequently mutated gene in lung tumors, but its prognostic role in admixed populations, suc...
High Inner Centromere Protein (INCENP) expression correlates with aggressive features and predicts poor prognosis in patients with invasive breast cancer
High Inner Centromere Protein (INCENP) expression correlates with aggressive features and predicts poor prognosis in patients with invasive breast cancer
Background: Inner centromere protein (INCENP) is a member of the chromosomal passenger complex (CPC) and plays a key role ...
Senescent tumor cells are frequently present at the invasion front - implications for improving disease control in patients with locally advanced prostate cancer
Senescent tumor cells are frequently present at the invasion front - implications for improving disease control in patients with locally advanced prostate cancer
Introduction: Local tumor invasion is a critical factor for the outcome of men with prostate cancer. In particular seminal...
Primary Effusion Lymphoma in an HIV-Negative Patient with Chronic Myeloid Leukemia Treated with Dasatinib
Primary Effusion Lymphoma in an HIV-Negative Patient with Chronic Myeloid Leukemia Treated with Dasatinib
Introduction: Primary effusion lymphoma (PEL) is a malignant lymphomatous effusion, which by definition is Kaposi sarcoma ...
Myeloid proliferations associated with Down syndrome: clinicopathologic characteristics of forty cases from five large academic institutions
Myeloid proliferations associated with Down syndrome: clinicopathologic characteristics of forty cases from five large academic institutions
Objectives: The incidence of myelodysplastic syndrome and acute myeloid leukemia is significantly increased in children wi...
NPM1-mutated acute myeloid leukemia: recent developments and open questions
NPM1-mutated acute myeloid leukemia: recent developments and open questions
Somatic mutations in the nucleophosmin (NPM1) gene occur in approximately 30% of de novo acute myeloid leukemias (AML), an...
Artificial intelligence in bone marrow histological diagnostics: potential applications and challenges
Artificial intelligence in bone marrow histological diagnostics: potential applications and challenges
The expanding digitalization of routine diagnostic histological slides holds a potential to apply artificial intelligence ...
Guidelines for Handling of Cytological Specimens in Cancer Genomic Medicine
Guidelines for Handling of Cytological Specimens in Cancer Genomic Medicine
Rapid advances are being made in cancer drug therapy. Since molecularly targeted therapy has been introduced, personalized...
miR-142-3p Suppresses Invasion and Adhesion of Mesothelioma Cells by Downregulating ITGAV
miR-142-3p Suppresses Invasion and Adhesion of Mesothelioma Cells by Downregulating ITGAV
<b><i>Introduction:</i></b> Malignant mesothelioma is an aggressive cancer associated with asbesto...
Clinical Value of Platelets and Coagulation Parameters in Predicting the Severity of Delta Variant SARS-CoV-2
Clinical Value of Platelets and Coagulation Parameters in Predicting the Severity of Delta Variant SARS-CoV-2
<b><i>Introduction:</i></b> The present study aimed to analyze the clinical features and laborator...
Clinical and Prognostic Impact of the Warburg Effect in Esophageal Carcinoma: Monocarboxylate Transporters as Candidates for Therapeutic Targeting
Clinical and Prognostic Impact of the Warburg Effect in Esophageal Carcinoma: Monocarboxylate Transporters as Candidates for Therapeutic Targeting
<b><i>Introduction:</i></b> Esophageal cancer (EC) seems to display increased glycolytic activity,...
Blood Liquid Biopsy in an Advanced Medullary Thyroid Carcinoma: A Case Study with Rearranged during Transfection Heterogeneity
Blood Liquid Biopsy in an Advanced Medullary Thyroid Carcinoma: A Case Study with Rearranged during Transfection Heterogeneity
<b><i>Introduction:</i></b> Liquid biopsy is an innovative and efficient method for studying circu...
Cancer registration, molecular marker status and adherence to the WHO 2016 classification of pathology reports for glioma diagnosed during 2017-2019 in Belgium
Cancer registration, molecular marker status and adherence to the WHO 2016 classification of pathology reports for glioma diagnosed during 2017-2019 in Belgium
Introduction: The objective of this study is to cross-check and if necessary, adjust registered ICD-O-3 topography and mor...
Renal cell carcinoma in end-stage renal disease: A retrospective study in patients from Hungary
Renal cell carcinoma in end-stage renal disease: A retrospective study in patients from Hungary
Introduction: End-stage renal disease (ESRD) and acquired cystic kidney disease (ACKD) are known risk factors for renal ce...
GATA3 Expression in Human Tumors: A Tissue Microarray Study on 16,557 Tumors
GATA3 Expression in Human Tumors: A Tissue Microarray Study on 16,557 Tumors
<b><i>Introduction:</i></b> GATA3 is a transcription factor involved in epithelial cell differenti...
Evaluation of the Implementation and Diagnostic Accuracy of the Paris Classification for Reporting Urinary Cytology in Voided Urine Specimens: A Cyto-Histological Correlation Study in a Cancer Center
Evaluation of the Implementation and Diagnostic Accuracy of the Paris Classification for Reporting Urinary Cytology in Voided Urine Specimens: A Cyto-Histological Correlation Study in a Cancer Center
<b><i>Introduction:</i></b> The Paris classification highlights the need to focus on accurately i...
Contents, Vol. 89, 2022
Contents, Vol. 89, 2022
Pathobiology...
Flow Cytometry Analysis Reveals a Wide Cytologic and Immunophenotypic Spectrum of Peripheral B Lymphocytes in Angioimmunoblastic T-Cell Lymphoma
Flow Cytometry Analysis Reveals a Wide Cytologic and Immunophenotypic Spectrum of Peripheral B Lymphocytes in Angioimmunoblastic T-Cell Lymphoma
<b><i>Introduction:</i></b> Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive T-cell lymp...
Lymphocyte Subsets in Cervicovaginal Lavage Specimens of HIV-Infected Women: A Surrogate Risk Marker of HPV-Associated Cervical Lesions
Lymphocyte Subsets in Cervicovaginal Lavage Specimens of HIV-Infected Women: A Surrogate Risk Marker of HPV-Associated Cervical Lesions
<b><i>Introduction:</i></b> To better understand the role of mucosa immunity in the development of...
Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics
Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics
<b><i>Introduction:</i></b> Colorectal carcinoma (CRC) is among the most common carcinomas in wome...
Evolutionary Changes in Pathology and Our Understanding of Disease
Evolutionary Changes in Pathology and Our Understanding of Disease
The history of pathology involves human dissections, autopsies, microscopy, as well as the development of histopathologica...
A Comparison of Tissue Dissection Techniques for Diagnostic, Prognostic, and Theragnostic Analysis of Human Disease
A Comparison of Tissue Dissection Techniques for Diagnostic, Prognostic, and Theragnostic Analysis of Human Disease
Histopathology has historically been the critical technique for the diagnosis and treatment of human disease. Today, genom...
The More Extensive the Spread through Air Spaces, the Worse the Prognosis Is: Semi-Quantitative Evaluation of Spread through Air Spaces in Pulmonary Adenocarcinomas
The More Extensive the Spread through Air Spaces, the Worse the Prognosis Is: Semi-Quantitative Evaluation of Spread through Air Spaces in Pulmonary Adenocarcinomas
<b><i>Introduction:</i></b> The extent of spread through air spaces (STAS) is less investigated am...
Autoimmune Thyroiditis Induced by Bartonella henselae (Cat-Scratch Disease) Might Be Reversible
Autoimmune Thyroiditis Induced by Bartonella henselae (Cat-Scratch Disease) Might Be Reversible
<b><i>Introduction:</i></b> <i>Bartonella henselae</i> infection leads to development ...
Tissue Fixation with a Formic Acid-Deprived Formalin Better Preserves DNA Integrity over Time
Tissue Fixation with a Formic Acid-Deprived Formalin Better Preserves DNA Integrity over Time
<b><i>Introduction:</i></b> Optimization of pre-analytic procedures and tissue processing is a bas...
Myeloid Sarcoma of the Breast as Blast Phase of JAK2-Mutated (Val617Phe Exon 14p) Essential Thrombocythemia: A Case Report and a Systematic Literature Review
Myeloid Sarcoma of the Breast as Blast Phase of JAK2-Mutated (Val617Phe Exon 14p) Essential Thrombocythemia: A Case Report and a Systematic Literature Review
<b><i>Introduction:</i></b> Myeloid sarcoma (MS) is a mass-forming proliferation of myeloid blasts...
Minichromosome Maintenance 4 Is Associated with Cancer Stemness and Poor Survival of Patients with Gastric Cancer
Minichromosome Maintenance 4 Is Associated with Cancer Stemness and Poor Survival of Patients with Gastric Cancer
<b><i>Introduction:</i></b> Gastric cancer (GC) is a leading cause of cancer-related death worldwi...
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