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Influences of Aged Bone Marrow Macrophages on Skeletal Health and Senescence
Influences of Aged Bone Marrow Macrophages on Skeletal Health and Senescence
The purpose of this review is to discuss the role of macrophages in the regulation of skeletal health with age, particular...
Osteocytes and Primary Cilia
Osteocytes and Primary Cilia
The purpose of this review is to provide a background on osteocytes and the primary cilium, discussing the role it plays i...
From Inflammation to Resolution: Specialized Pro-resolving Mediators in Posttraumatic Osteoarthritis
From Inflammation to Resolution: Specialized Pro-resolving Mediators in Posttraumatic Osteoarthritis
To provide a comprehensive overview of the inflammatory response following anterior cruciate ligament (ACL) injury and to ...
Racial and Ethnic Differences in Studies of the Gut Microbiome and Osteoporosis
Racial and Ethnic Differences in Studies of the Gut Microbiome and Osteoporosis
The purpose of this review is to summarize the scientific evidence published in the past 5 years examining the epidemiolog...
Role of the Peripheral Nervous System in Skeletal Development and Regeneration: Controversies and Clinical Implications
Role of the Peripheral Nervous System in Skeletal Development and Regeneration: Controversies and Clinical Implications
This review examines the diverse functional relationships that exist between the peripheral nervous system (PNS) and bone,...
Mitochondrial Genetics and Function as Determinants of Bone Phenotype and Aging
Mitochondrial Genetics and Function as Determinants of Bone Phenotype and Aging
The purpose of this review is to summarize the recently published scientific literature regarding the effects of mitochond...
Osteoporosis and Fracture Risk among Older US Asian Adults
Osteoporosis and Fracture Risk among Older US Asian Adults
This review summarizes the current knowledge regarding osteoporosis and fracture among older US Asian adults. Asian adults...
Fracture Risk in Patients with Hypoparathyroidism
Fracture Risk in Patients with Hypoparathyroidism
To summarize the recently published scientific evidence on fracture risk in hypoparathyroidism. Hypoparathyroidism is char...
Genetics of Diffuse Idiopathic Skeletal Hyperostosis and Ossification of the Spinal Ligaments
Genetics of Diffuse Idiopathic Skeletal Hyperostosis and Ossification of the Spinal Ligaments
The study aims to provide updated information on the genetic factors associated with the diagnoses ‘Diffuse Idiopath...
Sclerostin and Cardiovascular Disease
Sclerostin and Cardiovascular Disease
The role of wnt signalling in atherogenesis raises the possibility that the wnt inhibitor, sclerostin, provides a natural ...
Runt-related Transcription Factors and Gene Regulatory Mechanisms in Skeletal Development and Diseases
Runt-related Transcription Factors and Gene Regulatory Mechanisms in Skeletal Development and Diseases
Runt-related transcription factors (RUNX) play critical roles in skeletal development, metabolism, and diseases. In mammal...
Defects in Bone and Bone Marrow in Inherited Anemias: the Chicken or the Egg
Defects in Bone and Bone Marrow in Inherited Anemias: the Chicken or the Egg
Recently, there has been an increasing number of studies on the crosstalk between the bone and the bone marrow and how it ...
Cranial Neural Crest Cells Contribution to Craniofacial Bone Development and Regeneration
Cranial Neural Crest Cells Contribution to Craniofacial Bone Development and Regeneration
This review aims to summarize (i) the latest evidence on cranial neural crest cells (CNCC) contribution to craniofacial de...
Bone Trans-omics: Integrating Omics to Unveil Mechanistic Molecular Networks Regulating Bone Biology and Disease
Bone Trans-omics: Integrating Omics to Unveil Mechanistic Molecular Networks Regulating Bone Biology and Disease
Recent advancements in “omics” technologies and bioinformatics have afforded researchers new tools to study bo...
Bone Health in the Transgender and Gender Diverse Youth Population
Bone Health in the Transgender and Gender Diverse Youth Population
The purpose of this review is to summarize the scientific evidence on bone health in transgender and gender diverse (TGD) ...
The Multifaceted Effects of Osteocytic TGFβ Signaling on the Skeletal and Extraskeletal Functions of Bone
The Multifaceted Effects of Osteocytic TGFβ Signaling on the Skeletal and Extraskeletal Functions of Bone
To summarize the fundamental role of transforming growth factor beta (TGFβ) signaling in osteocytes and highlight the...
Application of Panoramic Radiography in the Detection of Osteopenia and Osteoporosis—Current State of the Art
Application of Panoramic Radiography in the Detection of Osteopenia and Osteoporosis—Current State of the Art
Osteoporosis ranks high among morbidities in the elderly as it is a natural process to lose bone, making them susceptible ...
Disparities in the Epidemiology and Management of Fragility Hip Fractures
Disparities in the Epidemiology and Management of Fragility Hip Fractures
The purpose of this review is to synthesize the recently published scientific evidence on disparities in epidemiology and ...
Disparities in the Prevalence of Osteoporosis and Osteopenia in Men and Women Living in Sub-Saharan Africa, the UK, and the USA
Disparities in the Prevalence of Osteoporosis and Osteopenia in Men and Women Living in Sub-Saharan Africa, the UK, and the USA
To review the rising prevalence of osteopenia and osteoporosis in sub-Saharan Africa and the challenges this poses to gove...
Early Life Programming of Skeletal Health
Early Life Programming of Skeletal Health
Increasing bone mineral accrual during childhood might delay the onset of osteoporosis. We discuss the scientific evidence...
Advances in Osteosarcoma
Advances in Osteosarcoma
This article gives a brief overview of the most recent developments in osteosarcoma treatment, including targeting of sign...
Post-Fracture Care Program: Pharmacological Treatment of Osteoporosis in Older Adults with Fragility Fractures
Post-Fracture Care Program: Pharmacological Treatment of Osteoporosis in Older Adults with Fragility Fractures
To present and discuss the recently published scientific evidence on the approach, mode of action, and timing of osteoporo...
Advances in Osteoporosis Therapy: Focus on Osteoanabolic Agents, Secondary Fracture Prevention, and Perioperative Bone Health
Advances in Osteoporosis Therapy: Focus on Osteoanabolic Agents, Secondary Fracture Prevention, and Perioperative Bone Health
This review summarizes recently published data and other developments around osteoanabolic osteoporosis therapies in patie...
Bone Health in Young Athletes: a Narrative Review of the Recent Literature
Bone Health in Young Athletes: a Narrative Review of the Recent Literature
The aim of this review is to discuss the most recent published scientific evidence regarding bone health in the pediatric ...
Checkpoint Inhibitors in Bone Metastatic Disease in Solid Tumors
Checkpoint Inhibitors in Bone Metastatic Disease in Solid Tumors
Bone is a common site of metastatic spread for solid tumors. Bone as an organ serves unique roles in the body’s stru...
Amino Acid Metabolism in Bone Metastatic Disease
Amino Acid Metabolism in Bone Metastatic Disease
Breast and prostate tumors frequently metastasize to the bone, but the underlying mechanisms for osteotropism remain elusi...
Influence of Osteocyte Lacunar-Canalicular Morphology and Network Architecture on Osteocyte Mechanosensitivity
Influence of Osteocyte Lacunar-Canalicular Morphology and Network Architecture on Osteocyte Mechanosensitivity
The goal of this review is to summarize recent findings related to modifications in osteocyte lacunar and canalicular morp...
Transition from Pediatric to Adult Health Care in Osteogenesis Imperfecta
Transition from Pediatric to Adult Health Care in Osteogenesis Imperfecta
Here, we review issues regarding the transition from pediatric to adult-focused health care for individuals with osteogene...