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The Gut-Bone Axis in Diabetes
The Gut-Bone Axis in Diabetes
To describe recent advances in the understanding of how gut-derived hormones regulate bone homeostasis in humans with emph...
Opportunistic Screening Techniques for Analysis of CT Scans
Opportunistic Screening Techniques for Analysis of CT Scans
Opportunistic screening is a combination of techniques to identify subjects of high risk for osteoporotic fracture using r...
The Role of Bone Cell Energetics in Altering Bone Quality and Strength in Health and Disease
The Role of Bone Cell Energetics in Altering Bone Quality and Strength in Health and Disease
Bone quality and strength are diminished with age and disease but can be improved by clinical intervention. Energetic path...
Bone Tissue Responsiveness To Mechanical Loading—Possible Long-Term Implications of Swimming on Bone Health and Bone Development
Bone Tissue Responsiveness To Mechanical Loading—Possible Long-Term Implications of Swimming on Bone Health and Bone Development
To revisit the bone tissue mechanotransduction mechanisms behind the bone tissue response to mechanical loading and, withi...
Rethinking the Genetic Etiology of Nonsyndromic Tooth Agenesis
Rethinking the Genetic Etiology of Nonsyndromic Tooth Agenesis
Genetic studies in humans and animal models have improved our understanding of the role of numerous genes in the etiology ...
Fragility Fractures of the Pelvis: Current Practices and Future Directions
Fragility Fractures of the Pelvis: Current Practices and Future Directions
To summarise the current evidence and clinical practices for patients with fragility fractures of the pelvis (FFP). FFPs a...
Glycemic Control and Bone in Diabetes
Glycemic Control and Bone in Diabetes
This review summarizes recent developments on the effects of glycemic control and diabetes on bone health. We discuss the ...
Osteoclast Recycling and the Rebound Phenomenon Following Denosumab Discontinuation
Osteoclast Recycling and the Rebound Phenomenon Following Denosumab Discontinuation
Inhibition of receptor activator of nuclear factor kappa-B ligand (RANKL) with denosumab is an effective treatment in a nu...
CSF1R as a Therapeutic Target in Bone Diseases: Obvious but Not so Simple
CSF1R as a Therapeutic Target in Bone Diseases: Obvious but Not so Simple
The purpose of the review is to summarize the expression and function of CSF1R and its ligands in bone homeostasis and con...
Correction to: Stopping Denosumab
Correction to: Stopping Denosumab
The author Elena Gonzalez Rodriguez is not properly referenced in PubMed. The reference shows as “Rodriguez E.G.R...
Effects of Gabapentin and Pregabalin on Calcium Homeostasis: Implications for Physical Rehabilitation of Musculoskeletal Tissues
Effects of Gabapentin and Pregabalin on Calcium Homeostasis: Implications for Physical Rehabilitation of Musculoskeletal Tissues
In this review, we discuss the mechanism of action of gabapentinoids and the potential consequences of long-term treatment...
Microfluidic Co-culture Platforms for Studying Osteocyte Regulation of Other Cell Types under Dynamic Mechanical Stimulation
Microfluidic Co-culture Platforms for Studying Osteocyte Regulation of Other Cell Types under Dynamic Mechanical Stimulation
Osteocytes are the most abundant cell type in bone. These unique cells act primarily as mechanosensors and play crucial ro...
Skeletal Muscle Complications in Chronic Kidney Disease
Skeletal Muscle Complications in Chronic Kidney Disease
To provide an overview of the recent literature investigating the pathophysiology of skeletal muscle changes, intervention...
Role of the Gut Microbiome in Skeletal Muscle Physiology and Pathophysiology
Role of the Gut Microbiome in Skeletal Muscle Physiology and Pathophysiology
This review aims to summarize the recent findings about the contribution of the gut microbiome to muscle pathophysiology a...
Relationship of Aging, Inflammation, and Skeletal Stem Cells and Their Effects on Fracture Repair
Relationship of Aging, Inflammation, and Skeletal Stem Cells and Their Effects on Fracture Repair
This review summarizes recent investigations into the cellular and molecular effects of skeletal aging on the inflammatory...
Fracture Risk in Vegetarians and Vegans: the Role of Diet and Metabolic Factors
Fracture Risk in Vegetarians and Vegans: the Role of Diet and Metabolic Factors
There is strong evidence that poor dietary intake of certain micro- and macro-nutrients can negatively affect bone health....
Pathways Controlling Formation and Maintenance of the Osteocyte Dendrite Network
Pathways Controlling Formation and Maintenance of the Osteocyte Dendrite Network
The purpose of this review is to discuss the molecular mechanisms involved in osteocyte dendrite formation, summarize the ...
Bone-Muscle Crosstalk: Musculoskeletal Complications of Chemotherapy
Bone-Muscle Crosstalk: Musculoskeletal Complications of Chemotherapy
Chemotherapy drugs combat tumor cells and reduce metastasis. However, a significant side effect of some chemotherapy strat...
A Review of CT-Based Fracture Risk Assessment with Finite Element Modeling and Machine Learning
A Review of CT-Based Fracture Risk Assessment with Finite Element Modeling and Machine Learning
We reviewed advances over the past 3 years in assessment of fracture risk based on CT scans, considering methods that use ...
Weight Loss Interventions and Skeletal Health in Persons with Diabetes
Weight Loss Interventions and Skeletal Health in Persons with Diabetes
Weight loss is recommended for improving glycemic control and reducing cardiovascular risk factors in persons with diabete...
Does Aging Activate T-cells to Reduce Bone Mass and Quality?
Does Aging Activate T-cells to Reduce Bone Mass and Quality?
Aging leads to decline in bone mass and quality starting at age 30 in humans. All mammals undergo a basal age-dependent de...
Attenuating Muscle Mass Loss in Critical Illness: the Role of Nutrition and Exercise
Attenuating Muscle Mass Loss in Critical Illness: the Role of Nutrition and Exercise
Impaired recovery following an intensive care unit (ICU) admission is thought related to muscle wasting. Nutrition and phy...
Muscle and Bone Defects in Metastatic Disease
Muscle and Bone Defects in Metastatic Disease
The present review addresses most recently identified mechanisms implicated in metastasis-induced bone resorption and musc...
Diabetes and Impaired Fracture Healing: A Narrative Review of Recent Literature
Diabetes and Impaired Fracture Healing: A Narrative Review of Recent Literature
Diabetes mellitus is a chronic metabolic disorder commonly encountered in orthopedic patients. Both type 1 and type 2 diab...
Single-Cell RNA Sequencing: Unravelling the Bone One Cell at a Time
Single-Cell RNA Sequencing: Unravelling the Bone One Cell at a Time
Bone is a complex tissue populated by a highly heterogeneous mix of cell types in different compartments. The endosteal co...
Exercise and Exercise Mimetics for the Treatment of Musculoskeletal Disorders
Exercise and Exercise Mimetics for the Treatment of Musculoskeletal Disorders
The incidence of musculoskeletal disorders affecting bones, joints, and muscles is dramatically increasing in parallel wit...
Correction to: Do Bisphosphonates Alleviate Pain in Children? A Systematic Review
Correction to: Do Bisphosphonates Alleviate Pain in Children? A Systematic Review
In a previous version of this publication, the author Mercedes Rodriguez Celin’s name was listed as M.R. Celin.
Correction to: Aging and Mechanoadaptive Responsiveness of Bone
Correction to: Aging and Mechanoadaptive Responsiveness of Bone
The author missed to include the below statement in the Acknowledgement of the original article.