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DAMPs, PAMPs, NLRs, RIGs, CLRs and TLRs – Understanding the Alphabet Soup in the Context of Bone Biology
DAMPs, PAMPs, NLRs, RIGs, CLRs and TLRs – Understanding the Alphabet Soup in the Context of Bone Biology
The purpose of this review is to summarize the current understanding of cell-autonomous innate immune pathways that contri...
Association Between Air Pollution and Osteoporosis with High-Risk Populations: A Narrative Review
Association Between Air Pollution and Osteoporosis with High-Risk Populations: A Narrative Review
Air pollution has been raised as a novel risk factor for osteoporosis, which impose a huge burden on both individuals and ...
Associations Among Estrogens, the Gut Microbiome and Osteoporosis
Associations Among Estrogens, the Gut Microbiome and Osteoporosis
The purpose of this Review was to summarize the evidence on the associations among estrogen status, cellular senescence, t...
Role of Chemokines and Cytokines in Prostate Cancer Skeletal Metastasis
Role of Chemokines and Cytokines in Prostate Cancer Skeletal Metastasis
Once prostate cancer (PCa) bone metastases develop, the prognosis dramatically declines. The precise mechanisms regulating...
Vitamin D Level Between Calcium-Phosphorus Homeostasis and Immune System: New Perspective in Osteoporosis
Vitamin D Level Between Calcium-Phosphorus Homeostasis and Immune System: New Perspective in Osteoporosis
Vitamin D is a key molecule in calcium and phosphate homeostasis; however, increasing evidence has recently shown that it ...
3D Analysis of Tooth Movement Using 3D Technology
3D Analysis of Tooth Movement Using 3D Technology
3D cone beam imaging (CBCT) has allowed clinicians to better understand the anatomical variations of cranial anatomy. One ...
Adiposity and Mineral Balance in Chronic Kidney Disease
Adiposity and Mineral Balance in Chronic Kidney Disease
Bone homeostasis is balanced between formation and resorption activities and remain in relative equilibrium. Under disease...
Between a Rock and a Short Place—The Impact of Nephrolithiasis on Skeletal Growth and Development Across the Lifespan
Between a Rock and a Short Place—The Impact of Nephrolithiasis on Skeletal Growth and Development Across the Lifespan
The impact of nephrolithiasis on skeletal growth and bone health across the life span of kidney stone formers is reviewed....
Vitamin D-Do Diet Recommendations for Health Remain Strong?
Vitamin D-Do Diet Recommendations for Health Remain Strong?
How will the scientific community and authoritative bodies define future nutritional requirements for vitamin D? At the In...
Extra-osseous Roles of the RANK-RANKL-OPG Axis with a Focus on Skeletal Muscle
Extra-osseous Roles of the RANK-RANKL-OPG Axis with a Focus on Skeletal Muscle
This review aims to consolidate recent observations regarding extra-osseous roles of the RANK-RANKL-OPG axis, primarily wi...
Nutrition and Osteoporosis Prevention
Nutrition and Osteoporosis Prevention
Osteoporosis affects 50% of women and 20% of men after the age of 50. Fractures are associated with significant morbidity,...
Lateral Compression Fragility Fractures of the Pelvis: Diagnosis, Classifications, and Modern Management
Lateral Compression Fragility Fractures of the Pelvis: Diagnosis, Classifications, and Modern Management
To describe the diagnosis, classification, and modern management of lateral compression fragility fractures of the pelvis....
Air Pollution and Osteoporosis
Air Pollution and Osteoporosis
The purpose of this review is to provide a background of osteoporosis and air pollution, discussing increasing incidence o...
PET/CT for the Opportunistic Screening of Osteoporosis and Fractures in Cancer Patients
PET/CT for the Opportunistic Screening of Osteoporosis and Fractures in Cancer Patients
In this review, we outline the different etiologies of osteoporosis in the oncologic setting and describe the basis for us...
Dairy and Exercise for Bone Health: Evidence from Randomized Controlled Trials and Recommendations for Future Research
Dairy and Exercise for Bone Health: Evidence from Randomized Controlled Trials and Recommendations for Future Research
To examine evidence from randomized controlled trials (RCTs) on how modifiable factors such as exercise and nutrition, wit...
The Fracture Phenotypes in Women and Men of 50 Years and Older with a Recent Clinical Fracture
The Fracture Phenotypes in Women and Men of 50 Years and Older with a Recent Clinical Fracture
We review the literature about patients 50 years and older with a recent clinical fracture for the presence of skeletal an...
Lignans from Sambucus williamsii Protect Bone Via Microbiome
Lignans from Sambucus williamsii Protect Bone Via Microbiome
Traditional Chinese Medicine has a unique system to diagnose and treat bone diseases with symptoms similar to those of ost...
Persistent uncertainties in optimal treatment approaches of secondary hyperparathyroidism and hyperphosphatemia in patients with chronic kidney disease
Persistent uncertainties in optimal treatment approaches of secondary hyperparathyroidism and hyperphosphatemia in patients with chronic kidney disease
This review is a critical analysis of treatment results obtained in clinical trials conducted in patients with chronic kid...
MicroRNAs and their Modulatory Effect on the Hallmarks of Osteosarcopenia
MicroRNAs and their Modulatory Effect on the Hallmarks of Osteosarcopenia
Osteosarcopenia is a geriatric syndrome associated with disability and mortality. This review summarizes the key microRNAs...
2D vs. 3D Evaluation of Osteocyte Lacunae - Methodological Approaches, Recommended Parameters, and Challenges: A Narrative Review by the European Calcified Tissue Society (ECTS)
2D vs. 3D Evaluation of Osteocyte Lacunae - Methodological Approaches, Recommended Parameters, and Challenges: A Narrative Review by the European Calcified Tissue Society (ECTS)
Quantification of the morphology of osteocyte lacunae has become a powerful tool to investigate bone metabolism, pathologi...
Molecular Deconvolution of Bone Marrow Adipose Tissue Interactions with Malignant Hematopoiesis: Potential for New Therapy Development
Molecular Deconvolution of Bone Marrow Adipose Tissue Interactions with Malignant Hematopoiesis: Potential for New Therapy Development
Along with a strong impact on skeletal integrity, bone marrow adipose tissue (BMAT) is an important modulator of the adult...
Efferocytosis and Bone Dynamics
Efferocytosis and Bone Dynamics
This review summarizes the recently published scientific evidence regarding the role of efferocytosis in bone dynamics and...
Photon-Counting Computed Tomography for Microstructural Imaging of Bone and Joints
Photon-Counting Computed Tomography for Microstructural Imaging of Bone and Joints
Recently, photon-counting computed tomography (PCCT) has been introduced in clinical research and diagnostics. This review...
Marrow Adipocyte Senescence in the Pathogenesis of Bone Loss
Marrow Adipocyte Senescence in the Pathogenesis of Bone Loss
Beyond aging, senescent cells accumulate during multiple pathological conditions, including chemotherapy, radiation, gluco...
Interplay Between Skeletal and Hematopoietic Cells in the Bone Marrow Microenvironment in Homeostasis and Aging
Interplay Between Skeletal and Hematopoietic Cells in the Bone Marrow Microenvironment in Homeostasis and Aging
In this review, we discuss the most recent scientific advances on the reciprocal regulatory interactions between the skele...
Insights into Craniofacial Development and Anomalies: Exploring Fgf Signaling in Zebrafish Models
Insights into Craniofacial Development and Anomalies: Exploring Fgf Signaling in Zebrafish Models
To illustrate the value of using zebrafish to understand the role of the Fgf signaling pathway during craniofacial skeleta...
Quercetin in Osteoporosis Treatment: A Comprehensive Review of Its Mechanisms and Therapeutic Potential
Quercetin in Osteoporosis Treatment: A Comprehensive Review of Its Mechanisms and Therapeutic Potential
This review aims to provide a theoretical basis and insights for quercetin’s clinical application in the prevention ...
Osteoimmunology of Fracture Healing
Osteoimmunology of Fracture Healing
The purpose of this review is to summarize what is known in the literature about the role inflammation plays during bone f...
Regulatory Effect of Osteocytes on Extramedullary and Bone Marrow Adipose Tissue Development and Function
Regulatory Effect of Osteocytes on Extramedullary and Bone Marrow Adipose Tissue Development and Function
This review summarizes evidence on osteocyte support of extramedullary and bone marrow adipocyte development and discusses...
Diagnosing Osteoporosis in Diabetes—A Systematic Review on BMD and Fractures
Diagnosing Osteoporosis in Diabetes—A Systematic Review on BMD and Fractures
Recently, the American Diabetes Association updated the 2024 guidelines for Standards of Care in Diabetes and recommend th...
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