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Fatty Acid Synthase Inhibitory Activity of Euphorbia peplus and its Secondary Metabolites
The morbidity of cancer and obesity has been rising at an epidemic rate in recent years. Fatty acid synthase (FAS) is the ...
Environmental Friendly Analysis: Development and Validation of UV-Visible Spectrophotometric Method for Methotrexate Quantification in Marketed Dosage Forms and Nano Transethosomes
Aim: This study aimed to develop a safe and effective green solvent-assisted UV-visible spectrophotometric method and vali...
Clopidogrel Loaded Albumin Nanoparticles for the Management of Atherosclerosis: Preparation and Optimization by Box-Behnken Design
This study aimed to formulate and optimize the clopidogrel loaded bovine serum albumin nanoparticles as a sustained drug d...
Sinapic Acid (3,5-dimethoxy-4-hydroxycinnamic Acid) as Potential Protective Agent Against Tacrolimus Induced Nephrotoxicity in MDCK Cells
The immunosuppressive agent tacrolimus (TAC), a calcineurin inhibitor (CNI), is a crucial component in solid organ transpl...
Combined Antihyperlipidemic Effect of Acetyl-L-Carnitine and Bupropion Against High Fat Diet-induced Hyperlipidemia Model
Numerous studies showed a positive association between depression and obesity. In this context, we evaluated the combined ...
Assessing the Efficacy of Melia azedarach Leaf Extracts as a Mosquito Control Agent Against Aedes aegypti and Culex quinquefasciatus
Mosquito-borne diseases pose a serious global health threat, with millions of people affected and a significant number of ...
Review on Pharmacological Activities, Extraction and Analytical Techniques of Bergenin
The present review aims to compile various pharmacological activities, extraction techniques, and analytical techniques fo...
An Insightful Overview on Teneligliptin Hydrobromide Hydrate: Analytical Strategies
Diabetes mellitus (DM) remains a persistent and significant global health challenge, profoundly affecting the well-being o...
Method Development and Validation of Valsartan by Using Stability-Indicating RP-HPLC Method
This study had the objective to establish and validate a reverse-phase high-performance liquid chromatography (RP-HPLC) te...
Oral Bioefficacy Enhancement of Capsaicin for the Effective Treatment of Rheumatoid Arthritis
Rheumatoid arthritis, often known as RA, is an autoimmune disorder that has a pathophysiology that is not completely under...
A Review on Profenofos and its Reproductive Toxicity
Pesticides are the most commonly used substances these days. Pesticides are chemicals that are used to combat toxins that ...
Therapeutic Lead Identification from Ginkgo biloba against Enzyme Causing Alzheimer's Disease Using in-vitro Studies Integrated Network Pharmacology and Molecular Docking
Despite extensive research outcomes, Alzheimer's disease (AD) still affects millions of people with a high risk of mortali...
Prospects of Chronotherapy in the Treatment of Diabetes Mellitus: A Review
In mammals, biological time plays an essential role in the rhythms of physiology and behavior. Circadian rhythm additional...
Preparation and Characterization of Iguratimod Oral Formulation Using IPNs of Carboxymethyl Tamarind Seed Gum and Cyclodextrin Nanosponges
In the present study, Iguratimod-loaded Cyclodextrin Nanosponges and carboxy methyl tamarind gum interpenetrating polymer ...
An Investigation of the Hypoglycemic and Antioxidant Activity of Pimpinella tirupatiensis in STZ-Induced Diabetic Rat Cardiac Tissue
This study examines the effects of Pimpinella tirupatiensis (Pt) aqueous extract on diabetic rats produced by streptozotoc...
Evaluation of Anti-Anxiety Effect of Perilla Frutescens Seed Extracts on Experimental Animals
Background: Perilla Frutescens (PF) has traditionally been used in depression-related diseases, as a sedative and anti-oxi...
Network Pharmacology-Based Evaluation of Therapeutic Potential of Passiflora edulis Leaves in Alzheimer's Disease
Alzheimer's disease (AD) is a progressive neurodegenerative, multi-pathological and multifactorial disease affecting aroun...
Design and Characterization of Lipid Based Freeze Dried Quercetin Nanosuspension with Improved Bioavailability
Quercetin, a remarkable flavonoid known for its extensive pharmacological benefits, faces challenges in its clinical utili...
Elucidation of Phytochemicals in Stem Part and Evaluation of their Antioxidant Properties of Vincetoxicum subramanii (A. N. Henry) Meve & Liede (Apocynaceae)
The species Vincetoxicum subramanii is a traditional medicinal plant of the Apocynaceae family and endemic to Southern Wes...
Synthesis, Characterization and In-Vivo Anti Convulsant Activity of "Benzimidazole and Its Derivatives by Using Aqueous Extract of Acacia Concinna Pods (20% w/v)"
Introduction: Benzimidazole is a heterocyclic hydrocarbon having unique basic structural characteristics in their molecula...
Navigating the Landscape of Alzheimer's Disease: From Epidemiology to Drug Re-purposing
Alzheimer's disease (AD) is a prevalent and complex neurodegenerative disorder, primarily affecting the elderly population...
Design, Development and Optimization of Bixa Orellana Extract Loaded Silver Nanoparticle
The current study describes a green method to make silver nanoparticles from bixa orellana extract (BOAgNPs). The applicat...
Comparative Study of Hepatoprotective and Hematinic Activities of Ethanolic Extracts of Flacourtia indica's Leaf and Stem Bark
This study aimed to scrutinize the effect of the ethanol extracts of leaf and stem bark of Flacourtia indica (F. indica) o...
Synthesis and In-Vitro Anti Bacterial Activity of (E)-1-(3-oxo-3-(p-tolyl) prop-1-en-1-yl)-5,5-Diphenylimidazolidine-2,4-Dione and its Derivatives
Introduction: 5, 5-diphenylimidazolidine is a heterocyclic hydrocarbon with distinctive basic structural properties in its...
Hypo-testicular Efficacy Assessment of H2O-methanol (60:40) Extract of Tinospora cordifolia (Willd.) Stem in Albino Rat: A Dose-dependent Study
Background: Tinospora cordifolia (Willd.) Miers. traditionally familiar as giloy or gulancha has been used as a traditiona...
Simultaneous UV-Visible Spectrophotometric Determination of Nelfinavir and Quercetin in Patented Pharmaceutical Formulation and Bulk by First-Order Derivative Spectroscopic Method
Aim: To develop and validate a simple, precise, accurate, and sensitive UV-visible spectrophotometric method for the simul...
Preparation and Characterization of Dapsone Emulgel 7.5% Using Quality by Design
The present study work was undertaken with the intent to develop a topical emulgel formulation of dapsone 7.5% which would...
Pharmacological Evaluation of Moringa oleifera Seeds Extract for Anti-Inflammatory Effects in a Mouse Model
Inflammation is a common immune response system to obnoxious stimuli like infectious agents, toxic substances injured, cel...
Virtual Screening of Active Biomolecules from Plumeria Acutifolia against PPAR-γ
Introduction: Thiazolidinediones are widely used synthetic antidiabetic agents. These agents affect the pumping power of h...
Parabens and Pancreatic Cancer
Background: Parabens (PBs) are one of the famous substances used as preservatives for a long time. New studies confirmed t...
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