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CN1699 Our Business - Guide for Agents
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313
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1933
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234
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98
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67
HUMAN IMMUNOLOGY
1
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125
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Ring Finger Protein 215 Negatively Regulates Type I IFN Production via Blocking NF-{kappa}B p65 Activation [INNATE IMMUNITY AND INFLAMMATION]
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B Cells Drive MHC Class I-Restricted CD4 T Cells to Induce Spontaneous Central Nervous System Autoimmunity [AUTOIMMUNITY]
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Neutrophil and Macrophage NADPH Oxidase 2 Differentially Control Responses to Inflammation and to Aspergillus fumigatus in Mice [INFECTIOUS DISEASE AND HOST RESPONSE]
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{gamma}{delta} TCRs Function as Innate-like Receptors in the Bovine {gamma}{delta} T Cell Response against Leptospira [ANTIGEN RECOGNITION AND RESPONSES]
Key PointsThis is the first description, to our knowledge, of bovine γδ TCR repertoires using the NGS approach.In the bovi...
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E6020, a TLR4 Agonist Adjuvant, Enhances Both Antibody Titers and Isotype Switching in Response to Immunization with Hapten-Protein Antigens and Is Diminished in Mice with TLR4 Signaling Insufficiency [IMMUNOTHERAPY AND VACCINES]
Key PointsWT and TLR4-SNP mice respond comparably to T-dependent and -independent Ags alone.TLR4-SNP mice exhibit reduced ...
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The Drosophila Toll Pathway in Innate Immunity: from the Core Pathway toward Effector Functions [BRIEF REVIEWS]
AbstractThe fruit fly Drosophila melanogaster Toll signaling pathway has an evolutionarily conserved role in controlling i...
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Cutting Edge: Neutrophils License the Maturation of Monocytes into Effective Antifungal Effectors [CUTTING EDGE]
Key PointsMonocytes have impaired antifungal effector function in neutropenic mice.STAT1 expression on CCR2+ monocytes is ...
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Cutting Edge: High-Dose Live Attenuated Influenza Vaccines Elicit Pulmonary Tissue-Resident Memory CD8+ T Cells in the Face of Pre-Existing Humoral Immunity [CUTTING EDGE]
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Histamine-Releasing Factor Is a Novel Alarmin Induced by House Dust Mite Allergen, Cytokines, and Cell Death [ALLERGY AND OTHER HYPERSENSITIVITIES]
Key PointsHRF secretion is enhanced by cytokines, HDM allergens, ATP, and adenosine.Several HDM allergens enhance HRF secr...
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{beta}-Glucosylceramides and Tocopherols Regulate Development and Function of Dendritic Cells [ALLERGY AND OTHER HYPERSENSITIVITIES]
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Transcriptional Profiling of Phagocytic Leukocytes and Microglia Reveals a Critical Role for Reactive Oxygen Species in Biofilm Containment during Staphylococcus aureus Craniotomy Infection [INFECTIOUS DISEASE AND HOST RESPONSE]
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Mechanisms of Corticosteroid Resistance in Type 17 Asthma [ALLERGY AND OTHER HYPERSENSITIVITIES]
Key PointsBlood LCN2 and SAA levels may be associated with a type 17 asthma subtype.LCN2 and SAAs are steroid-resistant IL...
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An AhR-Caspase Axis Mediated Antiviral Apoptosis in an Arthropod [INNATE IMMUNITY AND INFLAMMATION]
Key PointsA homolog of the AhR family named LvAhR was cloned and identified from L. vannamei.Caspases are novel target gen...
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Monocyte/Macrophage Heterogeneity during Skin Wound Healing in Mice [INNATE IMMUNITY AND INFLAMMATION]
Key PointsMos/Mϕs exhibit complex and dynamic heterogeneity during skin wound healing.Mos/Mϕs transit from proinflammatory...
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Correction: Extracellular Acidity Reprograms Macrophage Metabolism and Innate Responsiveness [CORRECTIONS]
Jiang, W., J. Le, P.-y. Wang, X. Cheng, M. Smelkinson, W. Dong, C. Yang, Y. Chu, P. M. Hwang, R. S. Munford, and M. Lu. 20...
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Mechanism of CD79A and CD79B Support for IgM+ B Cell Fitness through B Cell Receptor Surface Expression [MOLECULAR AND STRUCTURAL IMMUNOLOGY]
Key PointsHigh surface expression of IgM protects against apoptosis in human GC B cells.CD79A/B depletion resulted in loss...
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IL-7 Receptor Drives Early T Lineage Progenitor Expansion [IMMUNE SYSTEM DEVELOPMENT]
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Therapeutic Opportunities for Immunoreceptor-Engineered T Cell Therapy for Modulation of Alloimmunity [TRANSLATING IMMUNOLOGY]
AbstractAchieving immunosuppression-free immune tolerance to an allograft is one of the central goals of transplantation. ...
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Correction: Maternal Monocytes Respond to Cell-Free Fetal DNA and Initiate Key Processes of Human Parturition [CORRECTIONS]
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Sharks Provide Evidence for a Highly Complex TNFSF Repertoire in the Jawed Vertebrate Ancestor [IMMUNOGENETICS]
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Cross-Regulation of F-Box Protein FBXL2 with T-bet and TNF-{alpha} during Acute and Chronic Lung Allograft Rejection [TRANSPLANTATION]
Key PointsFBXO3/FBXL2 balance is significantly increased during lung allograft rejection.TNF-α negatively regulates FBXL2 ...
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Pre-Germinal Center Interactions with T Cells Are Natural Checkpoints to Limit Autoimmune B Cell Responses [IMMUNE REGULATION]
Key PointsInteractions between myelin Ag-specific T and B cells are of low quality.Autoimmune B cells express low levels o...
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Persistent Antigen Harbored by Alveolar Macrophages Enhances the Maintenance of Lung-Resident Memory CD8+ T Cells [MUCOSAL IMMUNOLOGY]
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PANoptosis: A Unique Innate Immune Inflammatory Cell Death Modality [BRIEF REVIEWS]
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Polarization and {beta}-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues [CLINICAL AND HUMAN IMMUNOLOGY]
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