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Real-life evaluation of supplemental anaerobic blood culture bottles: impact on diagnosis and therapeutic management of patients with suspected sepsis
The term bacteremia refers to the presence of bacteria within the bloodstream, which may manifest as an asymptomatic or sy...
Wnt signaling and the tumor microenvironment: implications for cancer progression and therapeutics
Wnt signaling and the tumor microenvironment: implications for cancer progression and therapeutics
The Wnt (Wingless/Integrated) signaling pathway is a highly conserved regulator of development, stem cell maintenance, and...
The impact of K-Ras Gly12 mutants on homeostasis and tumorigenesis in the colonic epithelium
The impact of K-Ras Gly12 mutants on homeostasis and tumorigenesis in the colonic epithelium
K-Ras represents one of the most frequently mutated and therapeutically relevant oncogenic drivers. Clinical and epidemiol...
Oncolytic Virus Hijacks GOT1 and Pyrimidinosomes to Fuel Pyrimidine Synthesis for Replication in tumor cells
Oncolytic viruses selectively infect and kill tumor cells, but the metabolic adaptations that support their replication re...
The default mode network in a hierarchical generative model of the brain
We embed the default mode network (DMN) within a predictive processing architecture, arguing that its core function is to ...
Correction: Oncogenic PI3K/AKT promotes the step-wise evolution of combination BRAF/MEK inhibitor resistance in melanoma
Correction: Oncogenic PI3K/AKT promotes the step-wise evolution of combination BRAF/MEK inhibitor resistance in melanoma
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
Astrocytic apelin mediates cortical neuronal function and prevents anxiety-like behaviors in mice
Astrocytic apelin mediates cortical neuronal function and prevents anxiety-like behaviors in mice
As a key adipokine that regulates vascular functions, apelin has recently been appreciated for its role in modulating brai...
Accurate and task-agnostic modeling of enzymatic reactions through multimodal relational learning
Available online 8 April 2026Author links open overlay panel, , , , , , , , , , , AbstractEnzymatic reactions play an emer...
Brief 12-item questionnaire can be used to assess health literacy in Finnish adults
Brief 12-item questionnaire can be used to assess health literacy in Finnish adults
As health information and services become increasingly digital, it is more important than ever that people can find, under...
Extracellular vesicles from menstrual blood cells show potential to stimulate cartilage repair
Extracellular vesicles from menstrual blood cells show potential to stimulate cartilage repair
New research by an interdisciplinary team in Lithuania has revealed a promising and unconventional approach to cartilage r...
Local sales bans on flavored tobacco in California linked to reduced youth vaping
Local sales bans on flavored tobacco in California linked to reduced youth vaping
Researchers from the University of California San Diego have found that local sales bans on flavored tobacco in California...
Older immigrants in Finland face barriers to social and healthcare services
Older immigrants in Finland face barriers to social and healthcare services
A new study conducted at the University of Eastern Finland highlights the challenges faced by older immigrants in Finland ...
Combined training improves fitness outcomes in heart failure patients
Combined training improves fitness outcomes in heart failure patients
Heart failure affects more than 64 million people worldwide (1%–3% in the general adult population) and its prevalence is ...
Landmark study establishes shared definition of mental wellbeing
Landmark study establishes shared definition of mental wellbeing
For decades, 'mental wellbeing' has been one of the most used, but least agreed upon, terms in mental health.
EV-RNAs show promise for IBD diagnosis and treatment
EV-RNAs show promise for IBD diagnosis and treatment
A research team led by Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, has published a comprehensive re...
Brain pathways combine memory and reward to guide behavior
Brain pathways combine memory and reward to guide behavior
New research from the University of Maryland, Baltimore County (UMBC) reveals how two different parts of the brain's m...
New research leads to increased understanding of longevity gains in the United States
New research leads to increased understanding of longevity gains in the United States
A new study co-authored by two University of Wisconsin–Madison professors suggests longevity gains across all states and r...
Alligator Bioscience provides an update on mitazalimab
Alligator Bioscience provides an update on mitazalimab
Alligator Bioscience, a clinical-stage biotechnology company developing tumor-directed immuno-oncology antibody drugs, tod...
A high-precision image-guided platform for studying spinal cord toxicity under ultra-high dose rate electron irradiation
A high-precision image-guided platform for studying spinal cord toxicity under ultra-high dose rate electron irradiation, ...
Neuroadaptive dynamics in prefrontal cortex during negative emotion regulation: A combined fNIRS-rTMS study
Deficits in negative emotion regulation represent a core transdiagnostic feature of affective disorders, including major d...
Apixaban, direct oral anticoagulants and psychiatric events: Innocent bystander or true safety signal?
Volume 407, 15 August 2026, 121752Author links open overlay panelEmanuel Raschi a, Charles Khouri b c, Chiara Gastaldon d,...