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Melatonin inhibits ferroptosis through the ATF3/GPX4 signaling pathway to relieve myocardial ischemia–reperfusion injury in rats
Melatonin inhibits ferroptosis through the ATF3/GPX4 signaling pathway to relieve myocardial ischemia–reperfusion injury in rats
Melatonin (MEL), functioning as a circulating hormone, is important for the regulation of ferroptosis in different health ...
Challenges in cellular agriculture: lessons from Pacific white shrimp, Litopenaeus vannamei
Challenges in cellular agriculture: lessons from Pacific white shrimp, Litopenaeus vannamei
The overall goal of this research was to develop an embryonic stem cell (ESC) line from the Pacific white shrimp, Litopena...
Detection of Tilapia parvovirus in farm-reared tilapia in India and its isolation using fish cell lines
Detection of Tilapia parvovirus in farm-reared tilapia in India and its isolation using fish cell lines
Tilapia parvovirus (TiPV) is an emerging viral pathogen and responsible for severe economic loss in tilapia culture produc...
Tianxiangdan suppresses foam cell formation by enhancing lipophagy and reduces the progression of atherosclerosis
Tianxiangdan suppresses foam cell formation by enhancing lipophagy and reduces the progression of atherosclerosis
The aim of this study is to assess the impact of Tianxiangdan (TXD) on lipophagy in foam cells and its underlying mechanis...
Urolithin B suppresses phenotypic switch in vascular smooth muscle cells induced by PDGF-BB via inhibiting the PI3K-AKT pathway
Urolithin B suppresses phenotypic switch in vascular smooth muscle cells induced by PDGF-BB via inhibiting the PI3K-AKT pathway
Atherosclerosis (AS) is a prevalent cardiovascular condition, and the growth and phenotypic switch of vascular smooth musc...
Using cationic liposomes as carriers for long dsRNA to trigger an antiviral response in rainbow trout cell lines
Using cationic liposomes as carriers for long dsRNA to trigger an antiviral response in rainbow trout cell lines
Long dsRNA induces the expression of type I interferons (IFNs) and IFN-stimulated genes (ISGs) to establish an antiviral s...
Efficacy determination of a disinfectant against channel catfish virus by in vitro and in vivo methods
Efficacy determination of a disinfectant against channel catfish virus by in vitro and in vivo methods
Channel catfish virus (CCV) poses a significant threat to catfish culture. Lack of effective vaccines and antiviral treatm...
Preliminary study on the potential damage of cigarette smoke extract in 3D human chondrocyte culture
Preliminary study on the potential damage of cigarette smoke extract in 3D human chondrocyte culture
Osteoarthritis (OA) is a chronic degenerative disease characterized by the progressive loss of articular cartilage. The ro...
OPA3 inhibits the cGAS-STING pathway mediated by mtDNA stress to promote colorectal cancer progression
OPA3 inhibits the cGAS-STING pathway mediated by mtDNA stress to promote colorectal cancer progression
Colorectal cancer (CRC) is an extremely harmful malignant tumor. Optic atrophy 3 (OPA3) is highly expressed in multiple tu...
Expression, prognosis, immunological infiltration, and DNA methylation of members of the SFRP gene family in colorectal cancer: a comparative bioinformatic and experimental analysis
Expression, prognosis, immunological infiltration, and DNA methylation of members of the SFRP gene family in colorectal cancer: a comparative bioinformatic and experimental analysis
This study aimed to investigate the expression, prognostic significance, methylation, and immune invasion levels of secret...
Maxing Yigan formula promotes cartilage regeneration by regulating chondrocyte autophagy in osteoarthritis
Maxing Yigan formula promotes cartilage regeneration by regulating chondrocyte autophagy in osteoarthritis
Maxing Yigan formula (MYF) is a traditional Chinese medicine (TCM) prescription used for the treatment of OA for decades i...
Chlorogenic acid suppresses the expression of matrix metalloproteinase-7 and cell invasiveness to almost the same extent as isofraxidin in human colorectal cancer cells
Chlorogenic acid suppresses the expression of matrix metalloproteinase-7 and cell invasiveness to almost the same extent as isofraxidin in human colorectal cancer cells
The expression of matrix metalloproteinase (MMP)-7 is reported to be correlated with invasion and metastasis of colorectal...
NCF-1 plays a pivotal role in the survival of adenocarcinoma cells of pancreatic and gastric origins
NCF-1 plays a pivotal role in the survival of adenocarcinoma cells of pancreatic and gastric origins
Reactive oxygen species (ROS) play a pivotal biological role in cells, with ROS function differing depending on cellular c...
Development and characterization of polyvinyl alcohol/gelatin/chitosan hydrogel for tissue engineering and wound healing applications using a fish cell line model
Development and characterization of polyvinyl alcohol/gelatin/chitosan hydrogel for tissue engineering and wound healing applications using a fish cell line model
Chitosan-based hydrogels have gained considerable attention in biomedical research due to their inherent biocompatibility,...
Correction: The adaptation of bovine embryonic stem cells to the changes of feeder layers
Correction: The adaptation of bovine embryonic stem cells to the changes of feeder layers
Correction: In Vitro Cellular & Developmental Biology - Animal (2023) 59:85-99The...
MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen–glucose deprivation/reoxygenation
MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen–glucose deprivation/reoxygenation
MicroRNA-146a-5p (miR-146a-5p) actively participates in the process of cerebral ischemia–reperfusion (CI/R) injury. ...
RO4929097 inhibits NICD3 to alleviate pulmonary hypertension via blocking Notch3/HIF-2α/FoxM1 signaling pathway
RO4929097 inhibits NICD3 to alleviate pulmonary hypertension via blocking Notch3/HIF-2α/FoxM1 signaling pathway
Pulmonary hypertension (PH) is a condition in which the smooth muscle cells (SMCs) in the pulmonary arteries multiply exce...
Enhanced design of pCMViR-TSC plasmid vector for sustainably high cargo gene expression in mammalian cells
Enhanced design of pCMViR-TSC plasmid vector for sustainably high cargo gene expression in mammalian cells
The first-generation pCMViR-TSC, implemented through the promoter sandwich rule, yields 10- to 100-fold higher gene expres...
Exosomal miR-590-3p derived from bone marrow mesenchymal stem cells promotes osteoblast differentiation and osteogenesis by targeting TGFBR1
Exosomal miR-590-3p derived from bone marrow mesenchymal stem cells promotes osteoblast differentiation and osteogenesis by targeting TGFBR1
Bone marrow mesenchymal stem cells (BMSCs) have been verified to be essential factors regulating osteogenic functions, whi...
Controlling spheroid attachment improves pancreatic beta cell differentiation from human iPS cells
Controlling spheroid attachment improves pancreatic beta cell differentiation from human iPS cells
Regenerative medicine using human induced pluripotent stem cells (hiPSCs) is available for treating type 1 diabetes; howev...
Pharmacoproteogenomic approach identifies on-target kinase inhibitors for cancer drug repositioning
Pharmacoproteogenomic approach identifies on-target kinase inhibitors for cancer drug repositioning
Drug repositioning of approved drugs offers advantages over de novo drug development for a rare type of cancer. To efficie...
Pluripotent cells derived from 50% epiboly zebrafish embryos
Pluripotent cells derived from 50% epiboly zebrafish embryos
Choorapoikayil S, Overvoorde J, Den HJ (2013) Deriving cell lines from zebrafish embryos and tumors. Zebrafish 10:316–325A...
Astragaloside promotes the secretion of MSC-derived exosomal miR-146a-5p by regulating TRAF6/NF-κB pathway to attenuate inflammation in high glucose-impaired endothelial cells
Astragaloside promotes the secretion of MSC-derived exosomal miR-146a-5p by regulating TRAF6/NF-κB pathway to attenuate inflammation in high glucose-impaired endothelial cells
This study aimed to explore the potential of using mesenchymal stem cell (MSC)-derived exosomes (MSC-Exos) pre-treated wit...
Optimization of embryonic stage for aggregation to generate chimeric pigs using gene-edited blastomeres
Optimization of embryonic stage for aggregation to generate chimeric pigs using gene-edited blastomeres
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates o...
IL-27 attenuated macrophage injury and inflammation induced by Mycobacterium tuberculosis by activating autophagy
IL-27 attenuated macrophage injury and inflammation induced by Mycobacterium tuberculosis by activating autophagy
Interleukin-27 (IL-27) is a cytokine that is reported to be highly expressed in the peripheral blood of patients with pulm...
Use of modified human hemangioma tissue cultures and human umbilical vein endothelial cell cultures to gain mechanistic insights into imiquimod treatment for infantile hemangioma
Use of modified human hemangioma tissue cultures and human umbilical vein endothelial cell cultures to gain mechanistic insights into imiquimod treatment for infantile hemangioma
Infantile hemangiomas (IH) are a common entity encountered by dermatologists, otolaryngologists, and other surgeons. Oral ...
The inhibitory effect of salidroside on RANKL-induced osteoclast formation via NFκB suppression
The inhibitory effect of salidroside on RANKL-induced osteoclast formation via NFκB suppression
Bone fractures are a prevalent clinical issue, and recent studies highlighted the promising potential of natural bone heal...
Adipose-derived cells surpass muscle-derived cells in primary cell isolation efficacy
Adipose-derived cells surpass muscle-derived cells in primary cell isolation efficacy
Anna T, Agnieszka BZ (2021) Adipose-derived stem cells secretome and its potential application in “stem cell-free therapy....
Pre-vascularized porous gelatin-coated β-tricalcium phosphate scaffolds for bone regeneration: an in vivo and in vitro investigation
Pre-vascularized porous gelatin-coated β-tricalcium phosphate scaffolds for bone regeneration: an in vivo and in vitro investigation
Vascularization is vital in bone tissue engineering, supporting development, remodeling, and regeneration. Lack of vascula...
Establishment and characterization of novel spontaneously immortalized larval cell lines from sablefish Anoplopoma fimbria
Establishment and characterization of novel spontaneously immortalized larval cell lines from sablefish Anoplopoma fimbria
Sablefish Anoplopoma fimbria is a groundfish of the North Pacific Ocean typically found in sea floor hab...
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