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Chlorogenic acid suppresses the expression of matrix metalloproteinase-7 and cell invasiveness to almost the same extent as isofraxidin in human colorectal cancer cells
Chlorogenic acid suppresses the expression of matrix metalloproteinase-7 and cell invasiveness to almost the same extent as isofraxidin in human colorectal cancer cells
The expression of matrix metalloproteinase (MMP)-7 is reported to be correlated with invasion and metastasis of colorectal...
NCF-1 plays a pivotal role in the survival of adenocarcinoma cells of pancreatic and gastric origins
NCF-1 plays a pivotal role in the survival of adenocarcinoma cells of pancreatic and gastric origins
Reactive oxygen species (ROS) play a pivotal biological role in cells, with ROS function differing depending on cellular c...
Development and characterization of polyvinyl alcohol/gelatin/chitosan hydrogel for tissue engineering and wound healing applications using a fish cell line model
Development and characterization of polyvinyl alcohol/gelatin/chitosan hydrogel for tissue engineering and wound healing applications using a fish cell line model
Chitosan-based hydrogels have gained considerable attention in biomedical research due to their inherent biocompatibility,...
Correction: The adaptation of bovine embryonic stem cells to the changes of feeder layers
Correction: The adaptation of bovine embryonic stem cells to the changes of feeder layers
Correction: In Vitro Cellular & Developmental Biology - Animal (2023) 59:85-99The...
MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen–glucose deprivation/reoxygenation
MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen–glucose deprivation/reoxygenation
MicroRNA-146a-5p (miR-146a-5p) actively participates in the process of cerebral ischemia–reperfusion (CI/R) injury. ...
RO4929097 inhibits NICD3 to alleviate pulmonary hypertension via blocking Notch3/HIF-2α/FoxM1 signaling pathway
RO4929097 inhibits NICD3 to alleviate pulmonary hypertension via blocking Notch3/HIF-2α/FoxM1 signaling pathway
Pulmonary hypertension (PH) is a condition in which the smooth muscle cells (SMCs) in the pulmonary arteries multiply exce...
Enhanced design of pCMViR-TSC plasmid vector for sustainably high cargo gene expression in mammalian cells
Enhanced design of pCMViR-TSC plasmid vector for sustainably high cargo gene expression in mammalian cells
The first-generation pCMViR-TSC, implemented through the promoter sandwich rule, yields 10- to 100-fold higher gene expres...
Exosomal miR-590-3p derived from bone marrow mesenchymal stem cells promotes osteoblast differentiation and osteogenesis by targeting TGFBR1
Exosomal miR-590-3p derived from bone marrow mesenchymal stem cells promotes osteoblast differentiation and osteogenesis by targeting TGFBR1
Bone marrow mesenchymal stem cells (BMSCs) have been verified to be essential factors regulating osteogenic functions, whi...
Controlling spheroid attachment improves pancreatic beta cell differentiation from human iPS cells
Controlling spheroid attachment improves pancreatic beta cell differentiation from human iPS cells
Regenerative medicine using human induced pluripotent stem cells (hiPSCs) is available for treating type 1 diabetes; howev...
Pharmacoproteogenomic approach identifies on-target kinase inhibitors for cancer drug repositioning
Pharmacoproteogenomic approach identifies on-target kinase inhibitors for cancer drug repositioning
Drug repositioning of approved drugs offers advantages over de novo drug development for a rare type of cancer. To efficie...
Pluripotent cells derived from 50% epiboly zebrafish embryos
Pluripotent cells derived from 50% epiboly zebrafish embryos
Choorapoikayil S, Overvoorde J, Den HJ (2013) Deriving cell lines from zebrafish embryos and tumors. Zebrafish 10:316–325A...
Astragaloside promotes the secretion of MSC-derived exosomal miR-146a-5p by regulating TRAF6/NF-κB pathway to attenuate inflammation in high glucose-impaired endothelial cells
Astragaloside promotes the secretion of MSC-derived exosomal miR-146a-5p by regulating TRAF6/NF-κB pathway to attenuate inflammation in high glucose-impaired endothelial cells
This study aimed to explore the potential of using mesenchymal stem cell (MSC)-derived exosomes (MSC-Exos) pre-treated wit...
Optimization of embryonic stage for aggregation to generate chimeric pigs using gene-edited blastomeres
Optimization of embryonic stage for aggregation to generate chimeric pigs using gene-edited blastomeres
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates o...
IL-27 attenuated macrophage injury and inflammation induced by Mycobacterium tuberculosis by activating autophagy
IL-27 attenuated macrophage injury and inflammation induced by Mycobacterium tuberculosis by activating autophagy
Interleukin-27 (IL-27) is a cytokine that is reported to be highly expressed in the peripheral blood of patients with pulm...
Use of modified human hemangioma tissue cultures and human umbilical vein endothelial cell cultures to gain mechanistic insights into imiquimod treatment for infantile hemangioma
Use of modified human hemangioma tissue cultures and human umbilical vein endothelial cell cultures to gain mechanistic insights into imiquimod treatment for infantile hemangioma
Infantile hemangiomas (IH) are a common entity encountered by dermatologists, otolaryngologists, and other surgeons. Oral ...
The inhibitory effect of salidroside on RANKL-induced osteoclast formation via NFκB suppression
The inhibitory effect of salidroside on RANKL-induced osteoclast formation via NFκB suppression
Bone fractures are a prevalent clinical issue, and recent studies highlighted the promising potential of natural bone heal...
Adipose-derived cells surpass muscle-derived cells in primary cell isolation efficacy
Adipose-derived cells surpass muscle-derived cells in primary cell isolation efficacy
Anna T, Agnieszka BZ (2021) Adipose-derived stem cells secretome and its potential application in “stem cell-free therapy....
Pre-vascularized porous gelatin-coated β-tricalcium phosphate scaffolds for bone regeneration: an in vivo and in vitro investigation
Pre-vascularized porous gelatin-coated β-tricalcium phosphate scaffolds for bone regeneration: an in vivo and in vitro investigation
Vascularization is vital in bone tissue engineering, supporting development, remodeling, and regeneration. Lack of vascula...
Establishment and characterization of novel spontaneously immortalized larval cell lines from sablefish Anoplopoma fimbria
Establishment and characterization of novel spontaneously immortalized larval cell lines from sablefish Anoplopoma fimbria
Sablefish Anoplopoma fimbria is a groundfish of the North Pacific Ocean typically found in sea floor hab...
Study on the mechanism of SAR1B in sodium acetate promoting milk fat synthesis
Study on the mechanism of SAR1B in sodium acetate promoting milk fat synthesis
Acetate can promote milk fat synthesis in dairy cow mammary epithelial cells (BMECs). In this study, gene function analysi...
Establishment, characterization, and sensory characteristics (taste and flavor) of an immortalized muscle cell line from the seven-band grouper Epinephelus septemfasciatus: implications for cultured seafood applications
Establishment, characterization, and sensory characteristics (taste and flavor) of an immortalized muscle cell line from the seven-band grouper Epinephelus septemfasciatus: implications for cultured seafood applications
Grouper muscle satellite cells (GMSCs) from the seven-band grouper (Epinephelus septemfasciatus) were isolated, and their ...
Hepatocyte nuclear factor 4α is a critical factor for the production of complement components in the liver
Hepatocyte nuclear factor 4α is a critical factor for the production of complement components in the liver
The complement system plays an important role in biological defense as an effector to eliminate microorganisms that invade...
Ginsenoside Re promotes proliferation of murine bone marrow mesenchymal stem cells in vitro through estrogen-like action
Ginsenoside Re promotes proliferation of murine bone marrow mesenchymal stem cells in vitro through estrogen-like action
Ginsenoside Re (GS-Re) is a major saponin monomer found in Panax ginseng Meyer. It has been shown to exhibit a wide range ...
Ginsenoside Rg1 treats chronic heart failure by downregulating ERK1/2 protein phosphorylation
Ginsenoside Rg1 treats chronic heart failure by downregulating ERK1/2 protein phosphorylation
In this study, we investigated the potential therapeutic mechanism of ginsenoside Rg1 (GRg1) in chronic heart failure (CHF...
Inhibition of FOXO3 ameliorates ropivacaine-induced nerve cell damage through the miR-126-5p/TRAF6 axis
Inhibition of FOXO3 ameliorates ropivacaine-induced nerve cell damage through the miR-126-5p/TRAF6 axis
Local anesthetics, such as ropivacaine (Ropi), are toxic to nerve cells. We aimed to explore the role of forkhead box O3 (...
Enhancement of the transfection efficiency of porcine spermatogonial stem cells by far-infrared radiation-based electroporation
Enhancement of the transfection efficiency of porcine spermatogonial stem cells by far-infrared radiation-based electroporation
Balantič K, Miklavčič D, Križaj I, Kra P (2021) The good and the bad of cell membrane electroporation. Acta Chim Slov 68:7...
Effect of transcription factor MEOX on insulin gene expression in glucagon-like peptide 1-secreting cells
Effect of transcription factor MEOX on insulin gene expression in glucagon-like peptide 1-secreting cells
Currently, the supply of beta cells for islet transplantation in the treatment of type 1 diabetes is limited. Enteroendocr...
Liriodendrin stimulates proliferation and milk protein synthesis of mammary epithelial cells via the PI3K-DDX18 signaling
Liriodendrin stimulates proliferation and milk protein synthesis of mammary epithelial cells via the PI3K-DDX18 signaling
Liriodendrin is a lignan compound that is involved in a wide variety of physiological functions, however it is unknown whe...
Role of NF-κB signaling pathway in H2O2-induced oxidative stress of hiPSCs
Role of NF-κB signaling pathway in H2O2-induced oxidative stress of hiPSCs
The balance between oxidation and antioxidation is crucial for the development of embryo. It is harmful to the early embry...
The role of MDM2 in angiogenesis: implications for endothelial tip cell formation
The role of MDM2 in angiogenesis: implications for endothelial tip cell formation
In the present study, we examined the role of MDM2 in the angiogenesis process and its potential association with the spro...
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