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Self-sustainable Catalytic Nucleic Acid Circuit Powered Hybrid CRISPR-Cas Systems for Point-of-Care Diagnosis of Circadian Clock Gene from Cell Lysates
Self-sustainable Catalytic Nucleic Acid Circuit Powered Hybrid CRISPR-Cas Systems for Point-of-Care Diagnosis of Circadian Clock Gene from Cell Lysates
The CRISPR-Cas13 systems have opened a new avenue for RNA detection due to their exceptional programmable collateral activ...
Enhanced Performance of Co-doped Antimony Electrode for pH Measurement in Marine Environments
Enhanced Performance of Co-doped Antimony Electrode for pH Measurement in Marine Environments
The antimony (Sb) electrode, despite its prevalent use for pH detection in complex environments, suffers from severe poten...
C18 Chain Post-modified Covalent Organic Framework Functional Silica Reversed-Phase Chromatographic Stationary Phase for Pharmaceutical Analysis
C18 Chain Post-modified Covalent Organic Framework Functional Silica Reversed-Phase Chromatographic Stationary Phase for Pharmaceutical Analysis
Covalent organic frameworks (COFs) have numerous advantages, including high specific surface area, good stability, and eas...
A Distance-Adjustable 3D DNA Scaffold Accelerated Quadruped DNA Walker for the Photoelectrochemical Biosensing of RNA in Phytophthora Infestans
A Distance-Adjustable 3D DNA Scaffold Accelerated Quadruped DNA Walker for the Photoelectrochemical Biosensing of RNA in Phytophthora Infestans
Phytophthora infestans, the causative agent of potato late blight, poses a destructive threat to global agricultural produ...
On-Site Analysis and Rapid Authentication of Valuable Agarwood Samples by Paper Capillary Spray Miniature Mass Spectrometry
On-Site Analysis and Rapid Authentication of Valuable Agarwood Samples by Paper Capillary Spray Miniature Mass Spectrometry
Agarwood is a resinous wood produced by plants of the genus Aquilaria in the Thymelaeaceae family after being injured. The...
Biopolymer Decorated Pencil Graphite Electrode for the In-situ Quantification of L-Tryptophan in Dietary Supplements
Biopolymer Decorated Pencil Graphite Electrode for the In-situ Quantification of L-Tryptophan in Dietary Supplements
A simplistic and novel electrochemical sensor for selectively detecting the essential amino acid tryptophan in dietary sup...
Polydopamine (PDA) Functionalized Eutectic Gallium–Indium (EGaIn) Nanoparticles as a Distortable Fluorescent Sensor for Pb2+ Detection
Polydopamine (PDA) Functionalized Eutectic Gallium–Indium (EGaIn) Nanoparticles as a Distortable Fluorescent Sensor for Pb2+ Detection
Fluorescent nanoparticles offer promising applications for bioimaging due to their exceptional attributes, including heigh...
A Novel Composite of Aptamer-Based Ti3C2Tx and Molecularly Imprinted Polymer with Double Recognition Property for Sensitive Electrochemical Detection of Ofloxacin
A Novel Composite of Aptamer-Based Ti3C2Tx and Molecularly Imprinted Polymer with Double Recognition Property for Sensitive Electrochemical Detection of Ofloxacin
A novel composite of aptamer-based Ti3C2Tx and molecularly imprinted polymer (Apt-Ti3C2Tx-MIP) with double recognition pro...
CRISPR-Cas12a Coupled with Universal Dual-mode Fluorescent Nanoparticles Platform for HPV Nucleic Acid Detection
CRISPR-Cas12a Coupled with Universal Dual-mode Fluorescent Nanoparticles Platform for HPV Nucleic Acid Detection
Cervical cancer is a prevalent gynecological malignancy, with approximately 90% of cases attributed to human papillomaviru...
Recent Progress in the Construction of Chiral Plasmonic Gold Nanostructures and Their Biochemical Sensing Applications
Recent Progress in the Construction of Chiral Plasmonic Gold Nanostructures and Their Biochemical Sensing Applications
Chirality, as the asymmetric property of nature, cannot fit its mirror image by translation or rotation. It is widespread ...
A Highly Sensitive Electrochemical Aptasensor for Kanamycin: Leveraging RecJf Exonuclease-Assisted Target Recycling and Hybridization Chain Reaction Signal Amplification
A Highly Sensitive Electrochemical Aptasensor for Kanamycin: Leveraging RecJf Exonuclease-Assisted Target Recycling and Hybridization Chain Reaction Signal Amplification
A highly sensitive electrochemical aptasensor was developed for the detection of kanamycin, employing a DNA signal amplifi...
Dual-Mode Colorimetric and Fluorescent Detection of Tumor Cells Based on Gold Nanoparticles-Loaded Phosphine Covalent Organic Frameworks
Dual-Mode Colorimetric and Fluorescent Detection of Tumor Cells Based on Gold Nanoparticles-Loaded Phosphine Covalent Organic Frameworks
Circulating tumor cells (CTCs) are important markers for cancer. The part of tumor cells that are detached from the primar...
Hydrophilic Chitosan/Covalent Organic Framework Composites for Efficient Solid-Phase Microextraction of Polar Phenolic Compounds Prior to Gas Chromatography: Mass Spectrometry Analysis
Hydrophilic Chitosan/Covalent Organic Framework Composites for Efficient Solid-Phase Microextraction of Polar Phenolic Compounds Prior to Gas Chromatography: Mass Spectrometry Analysis
Covalent organic frameworks (COFs) have been widely used to prepare solid-phase microextraction (SPME) coatings due to the...
Research Progress of Raman Spectroscopy and Imaging Techniques for the Pharmaceutical Analysis
Research Progress of Raman Spectroscopy and Imaging Techniques for the Pharmaceutical Analysis
Monitoring critical quality attributes in pharmaceutical manufacturing ensures that the final product meets specified requ...
Towards Improved Steroid Hormone Analysis: The Shift from Immunoassays to Mass Spectrometry
Towards Improved Steroid Hormone Analysis: The Shift from Immunoassays to Mass Spectrometry
Steroid hormones, synthesized from cholesterol via cytochrome P450 enzymes, are categorized into adrenocortical hormones a...
Ce-MOFs Fluorescent Probes with Different Ligands for Phosphate Detection
Ce-MOFs Fluorescent Probes with Different Ligands for Phosphate Detection
Phosphate plays a critical role in maintaining homeostasis and engaging in cellular metabolism and energy transduction wit...
Applications of Mass Spectrometry in Textile Analysis: An Overview
Applications of Mass Spectrometry in Textile Analysis: An Overview
Mass spectrometry (MS) stands as a pivotal tool for chemical analysis in the textile industry, capable of scrutinizing the...
Development of a Voltammetric Sensor for the Selective Determination of Tumour Biomarker-Vanillylmandelic Acid
Development of a Voltammetric Sensor for the Selective Determination of Tumour Biomarker-Vanillylmandelic Acid
This article describes the development of a molecularly imprinted polymers (MIPs) based sensor for the determination of va...
A Novel Multiple-Network Analysis Integrating Metabolomics and Pharmacology for Mechanism Study of Medicine: A Case Study of CDD-2101 Against Constipation
A Novel Multiple-Network Analysis Integrating Metabolomics and Pharmacology for Mechanism Study of Medicine: A Case Study of CDD-2101 Against Constipation
Constipation affects more than 14% of the global population with complex pathogenesis. Compound Traditional Chinese medici...
Rapid and Selective Detection of Foodborne Pathogens Using a Disposable Bio-sensing System Designed by Stepwise Antibody Immobilization on AuNPs@Cu-MOF Nanocomposite
Rapid and Selective Detection of Foodborne Pathogens Using a Disposable Bio-sensing System Designed by Stepwise Antibody Immobilization on AuNPs@Cu-MOF Nanocomposite
There is an urgent need to provide a rapid and selective method to analyze food and water samples contaminated with Staphy...
Electrochemical Detection of Pb(II) Ions in Aqueous Solution by Carbon Nanospheres Modified Boron-Doped Diamond Electrode
Electrochemical Detection of Pb(II) Ions in Aqueous Solution by Carbon Nanospheres Modified Boron-Doped Diamond Electrode
In this paper, a sensor using carbon nanospheres modified boron-doped diamond (CNs/BDD) electrode for detecting heavy meta...
An Array-based Photolithographically Patterned Electrochemical Sensing Platform for Highly Sensitive Determination of Uric Acid, Dopamine, l-Tryptophan, and Pyridoxine in Biological Samples
An Array-based Photolithographically Patterned Electrochemical Sensing Platform for Highly Sensitive Determination of Uric Acid, Dopamine, l-Tryptophan, and Pyridoxine in Biological Samples
Biomolecules play important roles in physiological functions and pharmacological characteristics of human body. Uric acid ...
UHPLC-MS/MS Approach for Following Nimodipine Saturation Kinetics in Acute Rat Brain Slice
UHPLC-MS/MS Approach for Following Nimodipine Saturation Kinetics in Acute Rat Brain Slice
Nimodipine (NMD) has gained increasing attention in the latest scientific studies as it can act alone or in combination wi...
Application of Oriented Molecular Imprinting Biosensors in Biomarker Detection
Application of Oriented Molecular Imprinting Biosensors in Biomarker Detection
With the rapid development of nanomaterials, the interdisciplinary cross-linking between nanomaterials and biomedical dete...
Antiparasitic Activity and Potential Active Compounds from Azadirachta Indica Revealed by Affinity Ultrafiltration Chromatography–Mass Spectrometry with Acetylcholinesterase and Lactate Dehydrogenases
Antiparasitic Activity and Potential Active Compounds from Azadirachta Indica Revealed by Affinity Ultrafiltration Chromatography–Mass Spectrometry with Acetylcholinesterase and Lactate Dehydrogenases
Azadirachta indica (A. indica) has traditionally been used to treat parasitic diseases, while its antiparasitic compounds ...
Non-Enzymatic Electrochemical Sensing of Bisphenol A in Drinking Water and Milk Using Bimetallic Nickel-Copper Metal–Organic Framework
Non-Enzymatic Electrochemical Sensing of Bisphenol A in Drinking Water and Milk Using Bimetallic Nickel-Copper Metal–Organic Framework
In recent years, there have been concerns about the toxicity of bisphenol A (BPA) in food packaging materials due to the p...
A High-Performance Electrochemical Analysis Platform for Ultrasensitive Detection of HTLV-1 DNA: Integrating Cascade Signal Amplification with λ-Exonuclease-Assisted Target Recycling and Enzyme Catalysis
A High-Performance Electrochemical Analysis Platform for Ultrasensitive Detection of HTLV-1 DNA: Integrating Cascade Signal Amplification with λ-Exonuclease-Assisted Target Recycling and Enzyme Catalysis
Human T-cell lymphophilic virus type 1 (HTLV-1), the known retrovirus causing cancer in humans, is closely associated with...
Fe3O4@SiO2-Protein A-oHSV/CD63 Ab for Capturing Virus and Exosomes
Fe3O4@SiO2-Protein A-oHSV/CD63 Ab for Capturing Virus and Exosomes
Protein A modified magnetic spheres (Fe3O4@SiO2-Protein A) with 22.7 emu/g saturation magnetization were prepared...
Cannabinoid Modulation of Monoamine Levels in Mouse Brain: Unveiling Neurochemical Dynamics through an Innovative High-performance Liquid Chromatography-Fluorescence Detection Bioanalysis
Cannabinoid Modulation of Monoamine Levels in Mouse Brain: Unveiling Neurochemical Dynamics through an Innovative High-performance Liquid Chromatography-Fluorescence Detection Bioanalysis
Homeostasis of monoaminergic pathways is compromised in aging and neurodegenerative/neurological diseases such as Alzheime...
Optimization of the Procedure for Gram Scale Synthesis of Silicon Rhodamine and its Application in Labeling BRD4 Kinase Inhibitor
Optimization of the Procedure for Gram Scale Synthesis of Silicon Rhodamine and its Application in Labeling BRD4 Kinase Inhibitor
Fu M, Xiao Y, Qian X, Zhao D, Xu Y. A design concept of long-wavelength fluorescent analogs of rhodamine dyes: replacement...
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