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Assessing and reducing phenotypic instability in cyanobacteria
Cyanobacteria have promising potential as sustainable cell factories. However, one challenge that is still largely unrepor...
Accurate determination of four tetracycline residues in chicken meat by isotope dilution-liquid chromatography/tandem mass spectrometry
Volume 1691, 22 February 2023, 463818Author links open overlay panelHighlights•Four tetracyclines were accurately determin...
Development of a unified gradient theory for ion-pair chromatography using oligonucleotide separations as a model case
Volume 1691, 22 February 2023, 463823Author links open overlay panelHighlights•The electrostatic theory applied for modeli...
Trends in monoliths: Packings, stationary phases and nanoparticles
Monoliths media are gaining interest as excellent substitutes to conventional particle-packed columns. Monolithic columns ...
Monitoring of ultra- and diafiltration processes by Kalman-filtered Raman measurements
Monitoring of ultra- and diafiltration processes by Kalman-filtered Raman measurements
Monitoring the protein concentration and buffer composition during the Ultrafiltration/Diafiltration (UF/DF) step enables ...
Irradiated lung cancer cell-derived exosomes modulate macrophage polarization by inhibiting MID1 via miR-4655-5p
Radiation Pneumonitis (RP) is one of the most common and severe complication in patients receiving thoracic radiotherapy. ...
A quantum mechanistic insight into the chemo- and regio-selective [3 + 2]-cycloaddition reaction of aryl hetaryl thioketones with diazoalkanes and nitrile oxide derivatives
In this quantum mechanistic study, density functional theory computations at the B3LYP hybrid level of theory, in addition...
Theoretical studies on the reaction mechanisms of the oxidation of tetramethylethylene using MO3Cl (M=Mn, Tc and Re)
A theoretical study on the reaction mechanisms of the addition of transition metal oxo complexes of the type MO3Cl (M = Mn...
Drug-tolerant detection of anti-drug antibodies in an antigen-binding assay using europium chelate fluorescence
Available online 28 January 2023, 113436Author links open overlay panelHighlights•Accurate anti-drug antibody (ADA) detect...
Preparation and application of sulfated lily polysaccharide bridged polyhedral oligomeric silsesquioxane hybrid organosilicas as stationary phase
Volume 1691, 22 February 2023, 463822Author links open overlay panelHighlights•Lily polysaccharide bridged POSS hybrid org...
Chemical profile of anti-epidemic sachet based on multiple sample preparation coupled with gas chromatography-mass spectrometry analysis combined with an embedded peaks resolution method and their action mechanisms
The anti-epidemic sachet (Fang Yi Xiang Nang, FYXN) in traditional Chinese medicine (TCM) can prevent COVID-19 through vol...
Dummy-template Pickering emulsion imprinted microspheres online pretreatment and analysis for the estrogens in cosmetics
Volume 1691, 22 February 2023, 463815Author links open overlay panelHighlights•A novel on-line SPE-HPLC analytical system ...
The development of microfluidic-based western blotting: Technical advances and future perspectives
Volume 1691, 22 February 2023, 463813Author links open overlay panelHighlights•A critical overview of advances in microflu...
Nonlinear liquid-liquid chromatography: Beyond a constant distribution coefficient
Volume 1691, 22 February 2023, 463824Author links open overlay panelHighlights•The first systematic study of liquid-liquid...
Preface: Advances in Environmental Analysis
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Cryo-EM image alignment: from pair-wise to joint with deep unsupervised difference learning
Cryo-electron microscopy (cryo-EM) single-particle analysis is a revolutionary imaging technique to resolve and visualize ...
Roxadustat and its failure: A comparative dynamic study
Roxadustat, a small-molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase domain 2 (HIF-PHD2) has been recentl...
Quantum Mechanical Elucidation on [3+2] cycloaddition reaction of aryl nitrile oxide with cyclopentenones
The [3 + 2] cycloaddition (32CA) reaction of benzonitrile oxide (BNO) with 4-substituted 4-hydroxy-2-cyclopentenone has be...
Mononuclear half-sandwich nd7 metallo drug complexes based on bidentate N∩N dendritic scaffolds: DFT (B3LYP; BP86 and B3PW91) examination
Through an use of three functionals (B3PW91, B3LYP and BP86) associated to a generic basis set LanL2DZ for transition meta...
Retention behavior of short double-stranded oligonucleotide and its potential impurities by anion-exchange chromatography under non-denaturing conditions
Volume 1691, 22 February 2023, 463808Author links open overlay panelHighlights•AEX for quality control of siRNA as non-den...
Engineering ribosomally synthesized and posttranslationally modified peptides as new antibiotics
Peptide natural products arise from two distinct pathway types: nonribosomal peptide synthetases (NRPSs) and ribosomally s...
Recent advances, opportunities and challenges in cybergenetic identification and control of biomolecular networks
Cybergenetics is a new area of research aimed at developing digital and biological controllers for living systems. Synthet...
Revisiting the Ramachandran plot based on statistical analysis of static and dynamic characteristics of protein structures
Ramachandran plots, which describe protein structures by plotting the dihedral angle pairs of the backbone on a two-dimens...
Identification of cancer protein biomarker based on cell specific peptide and its potential role in predicting tumor metastasis
The identification of tumor related membrane protein is important for both cancer diagnosis and targeted therapy. Currentl...
PARP inhibitor olaparib induced differential protein expression in cervical cancer cells
Volume 275, 20 March 2023, 104823Author links open overlay panelHighlights•This study provides the overview of proteomic c...
Electronic transport on the two state “ON–OFF” of 1,3,3-trimethylindolino-6′-nitrobenzopyrylospiran as a light-driven molecular optical switch: A first-principle study
Here, the electronic transport characteristics of the 1,3,3-trimethylindolino-6′-nitrobenzopyrylospiran were studied by us...
Unique selectivity of tetrahydrofuran-2-propanol-water ternary mobile phases on a superficially porous particle column in reversed-phase liquid chromatography
Volume 1690, 8 February 2023, 463801Author links open overlay panelHighlights•System maps for three tetrahydrofuran-2-prop...
One-step fabrication of hydrophobic metal-organic framework@covalent organic framework hybrid as sorbent for high-performance solid-phase extraction of flavonoids
Volume 1691, 22 February 2023, 463814Author links open overlay panelHighlights•A hydrophobic NH2[email protected]COF hybri...
Cross-reactivity analysis of milk proteins from different goat breeds with cow’s milk allergens using a proteomic approach
As the primary source of nutrients for infants, children and also adults, milk has been largely consumed across the world....
Chemo-structural diversity of anti-obesity compound database
Volume 120, May 2023, 108414Author links open overlay panelHighlights•A comprehensive cheminformatics study of anti-obesit...
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