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Fast Track Adaptation of Oncolytic Coxsackie B3 Virus to Resistant Colorectal Cancer Cells - a Method to Personalize Virotherapy
Fast Track Adaptation of Oncolytic Coxsackie B3 Virus to Resistant Colorectal Cancer Cells - a Method to Personalize Virotherapy
The efficacy of oncolytic viruses (OV) in cancer treatment depends on their ability to successfully infect and destroy tum...
Simultaneous determination of diquat, paraquat, glufosinate, and glyphosate in plasma by liquid chromatography/tandem mass spectrometry: from method development to clinical application
Simultaneous determination of diquat, paraquat, glufosinate, and glyphosate in plasma by liquid chromatography/tandem mass spectrometry: from method development to clinical application
Diquat (DQ), paraquat (PQ), glufosinate (GLU), and glyphosate (GLYP) are commonly used herbicides that have been confirmed...
Towards a reference material for microplastics’ number concentration—case study of PET in water using Raman microspectroscopy
Towards a reference material for microplastics’ number concentration—case study of PET in water using Raman microspectroscopy
Increasing demand for size-resolved identification and quantification of microplastic particles in drinking water and envi...
Development of an analytical method for the determination of more than 300 pesticides and metabolites in the particulate and gaseous phase of ambient air
Development of an analytical method for the determination of more than 300 pesticides and metabolites in the particulate and gaseous phase of ambient air
Pesticides can enter the atmosphere during spraying or after application, resulting in environmental or human exposure. Th...
‘From metabolism to metabolism’: holistic considerations on B-vitamin interactions, biofortification, and deficiencies
‘From metabolism to metabolism’: holistic considerations on B-vitamin interactions, biofortification, and deficiencies
In the post-Green Revolution era, disparities in dietary access, rising obesity rates, demographic shifts, adoption of pla...
Multidimensional LC-MS with 1D multi-method option and parallel middle-up and bottom-up MS acquisition for in-depth characterization of antibodies
Multidimensional LC-MS with 1D multi-method option and parallel middle-up and bottom-up MS acquisition for in-depth characterization of antibodies
Early twentieth century, Paul Ehrlich reported on “magic bullets” to cure a wide range of diseases thereby visionarily ref...
Separation of ochratoxins by centrifugal partition chromatography
Separation of ochratoxins by centrifugal partition chromatography
The present research work was dedicated to developing an efficient method based on liquid-liquid chromatography (centrifug...
Affinity purification of mAb from serum-containing hybridoma culture supernatant through a novel nanobody that discriminates mouse IgG from bovine IgG by recognizing the mouse kappa constant region (mCK)
Affinity purification of mAb from serum-containing hybridoma culture supernatant through a novel nanobody that discriminates mouse IgG from bovine IgG by recognizing the mouse kappa constant region (mCK)
Hybridoma technology is widely used to generate monoclonal antibodies, as the method can retain native heavy/light chain p...
UHRF1 inhibition mitigates vascular endothelial cell injury and ameliorates atherosclerosis in mice via regulating the SMAD7/YAP1 axis
UHRF1 inhibition mitigates vascular endothelial cell injury and ameliorates atherosclerosis in mice via regulating the SMAD7/YAP1 axis
Cardiovascular diseases (CVDs) are defined as circulatory system diseases related to the heart and blood vessels including...
Mammalian reovirus µ1 protein attenuates RIG-I and MDA5-mediated signaling transduction by blocking IRF3 phosphorylation and nuclear translocation
Mammalian reovirus µ1 protein attenuates RIG-I and MDA5-mediated signaling transduction by blocking IRF3 phosphorylation and nuclear translocation
The innate immune response is the host's first line of defense against virus invasion. During viral infection, host patter...
Screening of lung cancer serum biomarkers based on Boruta-shap and RFC-RFECV algorithms
Screening of lung cancer serum biomarkers based on Boruta-shap and RFC-RFECV algorithms
Available online 24 April 2024, 105180Author links open overlay panelHighlights•Six serum miRNAs were selected using Borut...
Proteomic analysis revealed that the oomyceticide phosphite exhibits multi-modal action in an oomycete pathosystem
Proteomic analysis revealed that the oomyceticide phosphite exhibits multi-modal action in an oomycete pathosystem
Available online 24 April 2024, 105181Author links open overlay panel, , , , Highlights•The oomyceticide phosphite may pos...
Discrimination and screening of volatile metabolites in atractylodis rhizoma from different varieties using headspace solid-phase microextraction-gas chromatography-mass spectrometry and headspace gas chromatography-ion mobility spectrometry, and ultra-fast gas chromatography electronic nose
Discrimination and screening of volatile metabolites in atractylodis rhizoma from different varieties using headspace solid-phase microextraction-gas chromatography-mass spectrometry and headspace gas chromatography-ion mobility spectrometry, and ultra-fast gas chromatography electronic nose
Atractylodis rhizoma is from the Composite family, which is the dried roots of A. lancea (Thunb.) DC. and A. chinensis (DC...
Editorial Special Symposium Issue HPLC 2023
Editorial Special Symposium Issue HPLC 2023
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Mechanistic studies of adsorption and ion exchange of Si(OH)4 molecules on the surface of scorodites
Mechanistic studies of adsorption and ion exchange of Si(OH)4 molecules on the surface of scorodites
Arsenic is a typical toxic element that can cause extreme harm to plant and animal health [[1], [2], [3], [4]]. However, a...
Inhibition of PI3K p110δ rebalanced Th17/Treg and reduced macrophages pyroptosis in LPS-induced sepsis
Inhibition of PI3K p110δ rebalanced Th17/Treg and reduced macrophages pyroptosis in LPS-induced sepsis
Sepsis, a systemic inflammatory response syndrome triggered by a dysregulated host response to trauma or infection, carrie...
Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders
Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders
Cardio-metabolic disorders (CMDs) are common in aging people and are pivotal risk factors for cardiovascular diseases (CVD...
Delineating molecular regulatory network of meat quality of longissimus dorsi indicated by transcriptomic, proteomic, and metabolomics analysis in rabbit
Delineating molecular regulatory network of meat quality of longissimus dorsi indicated by transcriptomic, proteomic, and metabolomics analysis in rabbit
Available online 22 April 2024, 105179Author links open overlay panel, , , , , , , , , , , , , , , Highlights•Slaughter pe...
Facile fabricate sandwich-structured molecularly imprinted dopamine polymer for simultaneously specific capture of Low-density lipoprotein and eliminate “bad cholesterol”
Facile fabricate sandwich-structured molecularly imprinted dopamine polymer for simultaneously specific capture of Low-density lipoprotein and eliminate “bad cholesterol”
LDL is a soluble complex formed by noncovalent interactions between lipids and proteins. Triglycerides and cholesterol com...
High-efficient separation of deoxyribonucleic acid from pathogenic bacteria by hedgehog-inspired magnetic nanoparticles microextraction
High-efficient separation of deoxyribonucleic acid from pathogenic bacteria by hedgehog-inspired magnetic nanoparticles microextraction
High purity deoxyribonucleic acid (DNA) is a crucial tool for biological research, and has been widely used in diagnostics...
Removal of heavy metal ions from wastewater using two-dimensional transition metal carbides
Removal of heavy metal ions from wastewater using two-dimensional transition metal carbides
Recently, two-dimensional (2D) materials have been representing wide applications such as sensing devices, catalysis, opto...
Effect of quercetin on the protein-substrate interactions in SIRT6: Insight from MD simulations
Effect of quercetin on the protein-substrate interactions in SIRT6: Insight from MD simulations
As members of the Class III family of histone deacetylases (HDACs), sirtuins have a variety of critical biological functio...
LncRNA-PCat19 acts as a ceRNA of miR-378a-3p to facilitate microglia activation and accelerate chronic neuropathic pain in rats by promoting KDM3A-mediated BDNF demethylation
LncRNA-PCat19 acts as a ceRNA of miR-378a-3p to facilitate microglia activation and accelerate chronic neuropathic pain in rats by promoting KDM3A-mediated BDNF demethylation
Neuropathic pain (NP), pain directly caused by a lesion or disease affecting the somatosensory system, is a common clinica...
2-Substituted-4,7-dihydro-4-ethylpyrazolo[1,5-a]pyrimidin-7-ones alleviate LPS-induced inflammation by modulating cell metabolism via CD73 upon macrophage polarization
2-Substituted-4,7-dihydro-4-ethylpyrazolo[1,5-a]pyrimidin-7-ones alleviate LPS-induced inflammation by modulating cell metabolism via CD73 upon macrophage polarization
Macrophages represent the first line of defense within the human body. Being widely distributed in all the anatomical dist...
Synthesis, in vitro Anti-HIV-1RT evaluation, molecular modeling, DFT and acute oral toxicity studies of some benzotriazole derivatives
Synthesis, in vitro Anti-HIV-1RT evaluation, molecular modeling, DFT and acute oral toxicity studies of some benzotriazole derivatives
Efforts to control HIV/AIDS since the late 1980 s have resulted in a global decline in new infections and deaths (De Clerc...
Interference of the gas chromatography- mass spectrometry instrumental background on the determination of trace cyclic volatile methylsiloxanes and exclusion of it by delayed injection
Interference of the gas chromatography- mass spectrometry instrumental background on the determination of trace cyclic volatile methylsiloxanes and exclusion of it by delayed injection
Cyclic volatile methyl siloxanes (cVMS), a subgroup of organosilicone, are organic compounds characterized by alternating ...
Production of Native Recombinant Proteins Using a Novel Split Intein Affinity Technology
Production of Native Recombinant Proteins Using a Novel Split Intein Affinity Technology
Affinity tags are frequently engineered into recombinant proteins to facilitate purification. Although this technique is p...
Computational design and preparation of water-compatible noncovalent imprinted microspheres
Computational design and preparation of water-compatible noncovalent imprinted microspheres
Molecularly imprinted polymers (MIPs) have garnered substantial attention as synthetic receptors for specific target molec...
Exploring the Impact of Polyvinylidenefluoride Membrane Physical Properties on the Enrichment Efficacy of Microfluidic Electro-membrane Extraction of Acidic Drugs
Exploring the Impact of Polyvinylidenefluoride Membrane Physical Properties on the Enrichment Efficacy of Microfluidic Electro-membrane Extraction of Acidic Drugs
Over recent decades, the quest for fast, efficient, and cost-effective extraction and analytical methods has gained signif...
A High-Throughput UPLC-MS-MS Bio-analytical Method for the Analysis of Veterinary Pharmaceutical Residues in Chicken Tissues, Application of Efficient-Valid-Green (EVG) Framework as a Competence Tool
A High-Throughput UPLC-MS-MS Bio-analytical Method for the Analysis of Veterinary Pharmaceutical Residues in Chicken Tissues, Application of Efficient-Valid-Green (EVG) Framework as a Competence Tool
Antibacterial drugs are receiving the biggest attention due to multiple hazards associated with their uncontrolled usage s...
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