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High separation performance of carbon dioxide-based poly(ether-carbonate) copolymer for gas chromatographic analyses
Volume 1682, 25 October 2022, 463493Highlights•Carbon dioxide-based poly(ether-carbonate) copolymers.•High-resolution sepa...
Changes in antibody binding and functionality after humanizing a murine scFv anti-IFN-α2: From in silico studies to experimental analysis
The structural and dynamic changes introduced during antibody humanization continue to be a topic open to new contribution...
Paper of the year
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The role of cuticle in fruit shelf-life
Ensuring the availability of high-quality fresh fruits requires the development of strategies to maintain prolonged shelf-...
Polyelectrolyte-grafted anion exchangers with hydrophilic intermediate layers for ion chromatography
Volume 1682, 25 October 2022, 463498Highlights•Polyelectrolyte-grafted anion exchangers with underlying hydrophilic layers...
A method of isolating and analysing drugs from cancer cells for preclinical research
Volume 1682, 25 October 2022, 463500Highlights•Analysis of drug absorption and retention in cancer cells for preclinical s...
Recent advances in capillary gel electrophoresis for the analysis of proteins
Volume 1682, 25 October 2022, 463453Highlights•In-depth information about the technology and the current state of the art....
Dual switch simulated moving bed chromatography: An optimal two‐fraction yielding separation process
Volume 1682, 25 October 2022, 463449Highlights•Novel Dual Switch SMBC yields two fractions for both, extract and raffinate...
Early-Career Complementologists (ECCO) – Past achievements and future directions
The Early-Career Complementologists (ECCO) is a task force that was established, in close collaboration with the European ...
Evaluating the clinical utility of measuring levels of factor H and the related proteins
After years of disappointing clinical results, the tide has finally changed and complement targeted-therapies have become ...
circVMA21 combining with TAF15 stabilizes SOCS3 mRNA to relieve septic lung injury through regulating NF-κB activation
BackgroundLung injury is a severe complication of sepsis, which brings great threats and challenges to human health. CircV...
Evaluation of refractometry methods for estimating passive immunity status in neonatal foals
The objective of this cross-sectional study was to determine the accuracy of the digital Brix and serum total protein (TP)...
Mathematical modeling and process analytical technology for continuous chromatography of biopharmaceutical products
Column chromatography is undeniably the industry standard for the purification of biotherapeutics beginning with the produ...
Phage biocontrol for reducing bacterial foodborne pathogens in produce and other foods
Bacteriophages (also known as phages) are bacterial viruses that specifically infect and kill bacteria. Use of phages to c...
Building mutational bridges between carbohydrate-active enzymes
To support the central role that carbohydrates and their derivatives play in the living world, Nature has evolved a large ...
Application of advanced machine learning algorithms for anomaly detection and quantitative prediction in protein A chromatography
Volume 1682, 25 October 2022, 463486Highlights•Advanced ML algorithms for column integrity breach and yield prediction hav...
Retention behaviors of pre-column derivatized mono-, di- and oligosaccharides in various modes of high performance liquid chromatography
Volume 1682, 25 October 2022, 463508Highlights•Various HPLC modes for the analysis of mono- and oligosaccharides.•Precolum...
Extending the performance of FcRn and FcγRIIIa affinity liquid chromatography for protein biopharmaceuticals
Volume 1682, 25 October 2022, 463518HIGHLIGHTS•Affinity liquid chromatography using FcRn and FcγRIIIa columns was critical...
On-line trace monitoring of volatile halogenated compounds in air by improved thermal desorption-gas chromatography-mass spectrometry
Volume 1682, 25 October 2022, 463507Highlights•Novel method was developed for ultratrace volatile halogenated compounds me...
Maigret’s zinc phosphide challenge
Maigret’s zinc phosphide challenge
If Sherlock Holmes is England’s most famous fictional detective, then there is little doubt that Inspector Maigret holds a...
Affinity-based isolation of extracellular vesicles and the effects on downstream molecular analysis
Affinity-based isolation of extracellular vesicles and the effects on downstream molecular analysis
Extracellular vesicles (EVs) are transport vesicles with diameters ranging from 30 to 1000 nm, secreted by cells ...