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Small but mighty: How microRNAs drive the deadly progression of cholangiocarcinoma
Use of computer-assisted surgery (CAS) and patient-specific plates (PSP) in orthognathic surgery has shown improved accura...
The impact of PD-L1 as a biomarker of cancer responses to combo anti-PD-1/CTLA-4
Survival of cancer cells relies mainly on their capacity to escape from immune surveillance. Activation of immune checkpoi...
The potential role of miRNAs in the pathogenesis of salivary gland cancer – A Focus on signaling pathways interplay
Salivary gland cancer (SGC) is an infrequent head and neck malignancy that encompasses a broad spectrum of tumors with var...
Touch imprint smear: A prerequisite to obtain better quality and “true” tumor RNA in breast tissues
Breast cancer, the most common feminine cancer diagnosed worldwide, is also the leading cause of cancer-associated deaths ...
RT-qPCR is helpful to distinguish the clinicopathological features of HER2 immunohistochemistry 0 and 1 +
Recurrent exotropia is common following surgery for monocular large angle constant sensory exotropia. Surgery is usually l...
The important role of miR-770 as a novel potential diagnostic and therapeutic target for human cancer and other diseases
MicroRNAs (miRNAs) are small single-stranded non-coding RNAs that are approximately 22 nucleotides long and are expressed ...
Liquid-based cytology (LBC) with immunocytochemical staining improves fine-needle aspiration cytology (FNA) performance for salivary gland tumors
BackgroundLiquid-based cytology (LBC), now used globally for the head and neck region, has been used at our hospital since...
Cytokine sustained delivery for cancer therapy; special focus on stem cell- and biomaterial- based delivery methods
The broad family of soluble proteins and glycoproteins known as cytokines plays an important role in modulating the immune...
OTUD1 chemosensitizes triple-negative breast cancer to doxorubicin by modulating P16 expression
In 2022, breast cancer (BC) accounted for 31% of all newly diagnosed cancers in women, making it the most prevalent female...
USP18 regulates the malignant phenotypes of glioblastoma stem cells
The etiopathogenesis of accompanying inflammatory phenomena and consequences of immunomodulation constitute a challenging ...
UCHL1 acts as a prognostic factor and promotes cancer stemness in cervical squamous cell carcinoma
Cervical cancer is one of the three major malignant tumors of female reproductive system, and its morbidity and mortality ...
Dysregulation of P53 in breast cancer: Causative factors and treatment strategies
Nonalcoholic steatohepatitis (NASH) is characterized by fat deposition, inflammation, and hepatocellular damage. The diagn...
BTG2 suppresses the growth and metastasis of cervical squamous cell carcinoma
Cervical cancer is the fourth most common malignancy in women and one of the leading causes of cancer deaths in women, acc...
Oncolytic vaccinia virus acts synergistically with anti-PD-L1 antibody to enhance the killing of colon cancer cells by CD8+ T cells
Colon cancer (CC) is the most common type of colorectal cancer (CRC) that is the 2nd leading cancer diagnosed globally [1]...
Sensitization of colon cancer cells to cisplatin by Fbxw7 via negative regulation of the Nox1-mTOR pathway
Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality worldwide [1]. Moreover, a number of adva...
Application of mesenchymal stem cells (MSCs) in neurodegenerative disorders: History, findings, and prospective challenges
The capacity for self-renewal and lineage-specific differentiation are two characteristics of stem cells. Mesenchymal stem...
Role of cancer stem cell-derived extracellular vesicles in cancer progression and metastasis
Cancer is a multifactorial disease and one of the leading causes of morbidity and mortality worldwide [1]. Therefore, it i...
PHB promotes bladder cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway
As a member of PHB (prohibitin1) family, PHB plays important roles in many cancers, but its property in bladder carcinoma ...
Modulation of microRNAs expression and cellular signaling pathways through curcumin as a potential therapeutical approach against ovarian cancer: A review
Numerous studies have indicated that the aberrant expression of LINC00963 is extensively present in various human tumors, ...
The diagnostic and prognostic role of miR-27a in cancer
MicroRNA-27a (miR-27a) has been reported to be abnormally expressed in patients with cancer, and it could play potential r...
“Paradoxical” p16 overexpression in cutaneous melanoma: Molecular and immunohistochemical analysis of a rare phenomenon with a focus on cell cycle regulatory molecules
Our understanding of the mutational landscape of cutaneous melanoma (CM) has made significant progress in the past several...
A review on the role of GHET1 in different cancers
Volume 247, July 2023, 154545Author links open overlay panel, , , , AbstractGastric cancer High Expressed Transcript 1 (GH...
A review on the role of LINC00472 in malignant and non-malignant disorders
Long intergenic non-protein coding RNA 472 (LINC00472) has been shown to regulate diverse cellular functions and contribut...
Proposal of a secure and efficient protocol for a murine oral carcinogenesis model induced by 4-nitroquinoline-1-oxide (4NQO)
Oral carcinogenesis is a multifactorial and intricate process including the expanding incidence of genetic changes that pr...
LncRNA NNT-AS1/hsa-miR-485–5p/HSP90 axis in-silico and clinical prospect correlated-to histologic grades-based CRC stratification: A step toward ncRNA Precision
Colorectal cancer (CRC) is a heterogeneous malignancy that affects the colon and rectum [1]. It is the third most prevalen...
Complement and complement regulatory proteins are upregulated in lungs of COVID-19 patients
We explored the pathological changes and the activation of local complement system in COVID-19 pneumonia. Lung paraffin se...
Roles of non-coding RNAs in cell death pathways involved in the treatment of resistance and recurrence of cancer
Data provided by the Global Burden of Diseases, Injuries, and Risk Factors Study has shown the presence of 2·88 million an...
The long non-coding RNA ZFAS1 promotes colorectal cancer progression via miR200b/ZEB1 axis
Cancer is one of the most common public health complications worldwide and continues to capture great attention [1]. Color...
miR-509–5p promotes colorectal cancer cell ferroptosis by targeting SLC7A11
In 2020, the incidence of colorectal cancer (CRC) represented 10% of the total cancer cases reported globally, with 9.40% ...
“Surface epithelial slackening” pattern in endometrioid carcinoma: A morphological feature for differentiating the POLE mutation-subtype from the no specific molecular profile subtype
Endometrial cancers are classified into mismatch repair (MMR) deficient- (MMRd), p53 mutation- (p53mut), DNA polymerase ep...
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