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Context Processing in Contextual and Cued Fear Extinction
Context Processing in Contextual and Cued Fear Extinction
Maren S, Phan KL, Liberzon I. The contextual brain: implications for fear conditioning, extinction and psychopathology. Na...
Deletion of Luzp2 Does Not Cause Hearing Loss in Mice
Deletion of Luzp2 Does Not Cause Hearing Loss in Mice
Deafness is the prevailing sensory impairment among humans, impacting every aspect of one's existence. Half of congeni...
Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury
Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury
Disruption of the blood-spinal cord barrier (BSCB) is a critical event in the secondary injury following spinal cord injur...
Liquid–Liquid Phase Separation within Dense-Core Vesicles in Sympathetic Adrenal Chromaffin Cells
Liquid–Liquid Phase Separation within Dense-Core Vesicles in Sympathetic Adrenal Chromaffin Cells
Banani SF, Lee HO, Hyman AA, Rosen MK. Biomolecular condensates: Organizers of cellular biochemistry. Nat Rev Mol Cell Bio...
Waking Up Brain with Electrical Stimulation to Boost Memory in Sleep: A Neuroscience Exploration
Waking Up Brain with Electrical Stimulation to Boost Memory in Sleep: A Neuroscience Exploration
Brodt S, Inostroza M, Niethard N, Born J. Sleep-a brain-state serving systems memory consolidation. Neuron 2023, 111: 1050...
The Neurovascular Unit Dysfunction in the Molecular Mechanisms of Epileptogenesis and Targeted Therapy
The Neurovascular Unit Dysfunction in the Molecular Mechanisms of Epileptogenesis and Targeted Therapy
Epilepsy is a multifaceted neurological syndrome characterized by recurrent, spontaneous, and synchronous seizures. The pa...
The Role of Corticotropin-Releasing Factor Receptor 1 in the Stress-Induced Alteration of Visual Properties in Primary Visual Cortex: Insights from the Single Prolonged Stress Model
The Role of Corticotropin-Releasing Factor Receptor 1 in the Stress-Induced Alteration of Visual Properties in Primary Visual Cortex: Insights from the Single Prolonged Stress Model
Cwik JC, Vahle N, Woud ML, Potthoff D, Kessler H, Sartory G. Reduced gray matter volume in the left prefrontal, occipital,...
Altered Cortical Information Interaction During Respiratory Events in Children with Obstructive Sleep Apnea-Hypopnea Syndrome
Altered Cortical Information Interaction During Respiratory Events in Children with Obstructive Sleep Apnea-Hypopnea Syndrome
Obstructive sleep apnea-hypopnea syndrome (OSAHS) significantly impairs children’s growth and cognition. This study ...
The Contributions of Thrombospondin-1 to Epilepsy Formation
The Contributions of Thrombospondin-1 to Epilepsy Formation
Epilepsy is a neural network disorder caused by uncontrolled neuronal hyperexcitability induced by an imbalance between ex...
Chimeric Monkey Born Alive with a High Contribution of Donor Cells
Chimeric Monkey Born Alive with a High Contribution of Donor Cells
Zheng C, Ballard EB, Wu J. The road to generating transplantable organs: From blastocyst complementation to interspecies c...
The Application of Extended Reality in Treating Children with Autism Spectrum Disorder
The Application of Extended Reality in Treating Children with Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder in children, characterized by social interaction, c...
L-Type Calcium Channel Modulates Low-Intensity Pulsed Ultrasound-Induced Excitation in Cultured Hippocampal Neurons
L-Type Calcium Channel Modulates Low-Intensity Pulsed Ultrasound-Induced Excitation in Cultured Hippocampal Neurons
As a noninvasive technique, ultrasound stimulation is known to modulate neuronal activity both in vitro and in vivo. The l...
SMART (Splitting-Merging Assisted Reliable) Independent Component Analysis for Extracting Accurate Brain Functional Networks
SMART (Splitting-Merging Assisted Reliable) Independent Component Analysis for Extracting Accurate Brain Functional Networks
Functional networks (FNs) hold significant promise in understanding brain function. Independent component analysis (ICA) h...
GABAergic Interneuron Cell Therapy for Drug-Resistant Epilepsy
GABAergic Interneuron Cell Therapy for Drug-Resistant Epilepsy
Thijs RD, Surges R, O’Brien TJ, Sander JW. Epilepsy in adults. Lancet 2019, 393: 689–701.Article  PubMed  ...
Positron Emission Tomography Imaging of Synaptic Dysfunction in Parkinson’s Disease
Positron Emission Tomography Imaging of Synaptic Dysfunction in Parkinson’s Disease
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases with a complex pathogenesis. Aggregati...
Emerging Human Pluripotent Stem Cell-Based Human–Animal Brain Chimeras for Advancing Disease Modeling and Cell Therapy for Neurological Disorders
Emerging Human Pluripotent Stem Cell-Based Human–Animal Brain Chimeras for Advancing Disease Modeling and Cell Therapy for Neurological Disorders
Human pluripotent stem cell (hPSC) models provide unprecedented opportunities to study human neurological disorders by rec...
Dopaminergic Remodeling During a Critical Developmental Window: Linking Drug Use to Adult Aggression
Dopaminergic Remodeling During a Critical Developmental Window: Linking Drug Use to Adult Aggression
Kim Y, Simon NW, Wood J, Moghaddam B. Reward anticipation is encoded differently by adolescent ventral tegmental area neur...
Face-Specific Activity in the Ventral Stream Visual Cortex Linked to Conscious Face Perception
Face-Specific Activity in the Ventral Stream Visual Cortex Linked to Conscious Face Perception
When presented with visual stimuli of face images, the ventral stream visual cortex of the human brain exhibits face-speci...
mTORC2: The “Ace in the Hole” for a Broader Control of Epileptic Seizures?
mTORC2: The “Ace in the Hole” for a Broader Control of Epileptic Seizures?
Thijs RD, Surges R, O’Brien TJ, Sander JW. Epilepsy in adults. Lancet 2019, 393: 689–701.Article  ...
LH-Nts Neurons Regulate VTA Calcium Dynamics Via Releasing GABA and Nts
LH-Nts Neurons Regulate VTA Calcium Dynamics Via Releasing GABA and Nts
Bartfai T, Iverfeldt K, Fisone G, Serfözö P. Regulation of the release of coexisting neurotransmitters. Annu Rev Pharmacol...
Interactions Between Extracellular Vesicles and Autophagy in Neuroimmune Disorders
Interactions Between Extracellular Vesicles and Autophagy in Neuroimmune Disorders
Neuroimmune disorders, such as multiple sclerosis, neuromyelitis optica spectrum disorder, myasthenia gravis, and Guillain...
Nanoscale Reorganization of Glutamate Receptors Underlies Synaptic Plasticity and Pathology
Nanoscale Reorganization of Glutamate Receptors Underlies Synaptic Plasticity and Pathology
Gou XZ, Ramsey AM, Tang AH. Re-examination of the determinants of synaptic strength from the perspective of superresolutio...
Tetherless Optical Neuromodulation: Wavelength from Orange-red to Mid-infrared
Tetherless Optical Neuromodulation: Wavelength from Orange-red to Mid-infrared
Optogenetics, a technique that employs light for neuromodulation, has revolutionized the study of neural mechanisms and th...
Neural Circuitry Involving Substance P in Male Sexual Behavior
Neural Circuitry Involving Substance P in Male Sexual Behavior
This highlight was supported by grants from the National Natural Science Foundation of China (32125018 and 32071005), the ...
Functional Changes in Astrocytes Lead to Cognitive Deficits After Social Deprivation
Functional Changes in Astrocytes Lead to Cognitive Deficits After Social Deprivation
Lin L, Cao B, Chen W, Li J, Zhang Y, Guo VY. Association of adverse childhood experiences and social isolation with later-...
Aβ-Aggregation-Generated Blue Autofluorescence Illuminates Senile Plaques as well as Complex Blood and Vascular Pathologies in Alzheimer’s Disease
Aβ-Aggregation-Generated Blue Autofluorescence Illuminates Senile Plaques as well as Complex Blood and Vascular Pathologies in Alzheimer’s Disease
Senile plaque blue autofluorescence was discovered around 40 years ago, however, its impact on Alzheimer’s disease (...
MDGA2 Constrains Glutamatergic Inputs Selectively onto CA1 Pyramidal Neurons to Optimize Neural Circuits for Plasticity, Memory, and Social Behavior
MDGA2 Constrains Glutamatergic Inputs Selectively onto CA1 Pyramidal Neurons to Optimize Neural Circuits for Plasticity, Memory, and Social Behavior
Synapse organizers are essential for the development, transmission, and plasticity of synapses. Acting as rare synapse sup...
Distributions of Visual Receptive Fields from Retinotopic to Craniotopic Coordinates in the Lateral Intraparietal Area and Frontal Eye Fields of the Macaque
Distributions of Visual Receptive Fields from Retinotopic to Craniotopic Coordinates in the Lateral Intraparietal Area and Frontal Eye Fields of the Macaque
Even though retinal images of objects change their locations following each eye movement, we perceive a stable and continu...
Abnormal Innervation, Demyelination, and Degeneration of Spiral Ganglion Neurons as Well as Disruption of Heminodes are Involved in the Onset of Deafness in Cx26 Null Mice
Abnormal Innervation, Demyelination, and Degeneration of Spiral Ganglion Neurons as Well as Disruption of Heminodes are Involved in the Onset of Deafness in Cx26 Null Mice
GJB2 gene mutations are the most common causes of autosomal recessive non-syndromic hereditary deafness. For individuals s...
Myosin Va-dependent Transport of NMDA Receptors in Hippocampal Neurons
Myosin Va-dependent Transport of NMDA Receptors in Hippocampal Neurons
N-methyl-D-aspartate receptor (NMDAR) trafficking is a key process in the regulation of synaptic efficacy and brain functi...
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