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Single-Neuron Reconstruction of the Macaque Primary Motor Cortex Reveals the Diversity of Neuronal Morphology
Single-Neuron Reconstruction of the Macaque Primary Motor Cortex Reveals the Diversity of Neuronal Morphology
Geyer S, Matelli M, Luppino G, Zilles K. Functional neuroanatomy of the primate isocortical motor system. Anat Embryol 200...
Correction to: Scorpion Venom Heat-Resistant Peptide is Neuroprotective Against Cerebral Ischemia-Reperfusion Injury in Association with the NMDA-MAPK Pathway
Correction to: Scorpion Venom Heat-Resistant Peptide is Neuroprotective Against Cerebral Ischemia-Reperfusion Injury in Association with the NMDA-MAPK Pathway
Xu-Gang Wang, Dan-Dan Zhu, and Na Li have contributed equally to this work.Liaoning Provincial Key Laboratory of Cerebral ...
The Paraventricular Hypothalamus: A Sorting Center for Visceral and Somatic Pain
The Paraventricular Hypothalamus: A Sorting Center for Visceral and Somatic Pain
Penfield W, Boldrey E. Somatic motor and sensory representation in the cerebral cortex as studied by electrical stimulatio...
Prediction of Pharmacoresistance in Drug-Naïve Temporal Lobe Epilepsy Using Ictal EEGs Based on Convolutional Neural Network
Prediction of Pharmacoresistance in Drug-Naïve Temporal Lobe Epilepsy Using Ictal EEGs Based on Convolutional Neural Network
Approximately 30%–40% of epilepsy patients do not respond well to adequate anti-seizure medications (ASMs), a condit...
Genetic Etiology Link to Brain Function Underlying ADHD Symptoms and its Interaction with Sleep Disturbance: An ABCD Study
Genetic Etiology Link to Brain Function Underlying ADHD Symptoms and its Interaction with Sleep Disturbance: An ABCD Study
Attention deficit hyperactivity disorder (ADHD), a prevalent neurodevelopmental disorder influenced by both genetic and en...
The Role and Mechanisms of Ubiquitin-Proteasome System-Mediated Ferroptosis in Neurological Disorders
The Role and Mechanisms of Ubiquitin-Proteasome System-Mediated Ferroptosis in Neurological Disorders
Ferroptosis is a form of cell death elicited by an imbalance in intracellular iron concentrations, leading to enhanced lip...
Type 2 Diabetes Mellitus Exacerbates Pathological Processes of Parkinson's Disease: Insights from Signaling Pathways Mediated by Insulin Receptors
Type 2 Diabetes Mellitus Exacerbates Pathological Processes of Parkinson's Disease: Insights from Signaling Pathways Mediated by Insulin Receptors
Parkinson’s disease (PD), a chronic and common neurodegenerative disease, is characterized by the progressive loss o...
Pseudogene Lamr1-ps1 Aggravates Early Spatial Learning Memory Deficits in Alzheimer’s Disease Model Mice
Pseudogene Lamr1-ps1 Aggravates Early Spatial Learning Memory Deficits in Alzheimer’s Disease Model Mice
Alzheimer’s disease (AD), a neurodegenerative disorder with complex etiologies, manifests through a cascade of patho...
To Attack or Not: A Neural Circuit Coding Sexually Dimorphic Aggression
To Attack or Not: A Neural Circuit Coding Sexually Dimorphic Aggression
Lin D, Boyle MP, Dollar P, Lee H, Lein ES, Perona P. Functional identification of an aggression locus in the mouse hypotha...
Halting the Progression of Alzheimer’s Disease: Is the Goal in Sight?
Halting the Progression of Alzheimer’s Disease: Is the Goal in Sight?
Selkoe DJ, Hardy J. The amyloid hypothesis of Alzheimer’s disease at 25years. EMBO Mol Med 2016, 8: 595–608.Article  C...
Neuronal Regulation of Feeding and Energy Metabolism: A Focus on the Hypothalamus and Brainstem
Neuronal Regulation of Feeding and Energy Metabolism: A Focus on the Hypothalamus and Brainstem
In the face of constantly changing environments, the central nervous system (CNS) rapidly and accurately calculates the bo...
Conditional Tnfaip6-Knockout in Inner Ear Hair Cells Does not Alter Auditory Function
Conditional Tnfaip6-Knockout in Inner Ear Hair Cells Does not Alter Auditory Function
Noise-induced hearing loss is a worldwide public health issue that is characterized by temporary or permanent changes in h...
Deciphering the Role of Shank3 in Dendritic Morphology and Synaptic Function Across Postnatal Developmental Stages in the Shank3B KO Mouse
Deciphering the Role of Shank3 in Dendritic Morphology and Synaptic Function Across Postnatal Developmental Stages in the Shank3B KO Mouse
Autism Spectrum Disorder (ASD) is marked by early-onset neurodevelopmental anomalies, yet the temporal dynamics of genetic...
Inhibition of the cGAS‑STING Pathway Reduces Cisplatin-Induced Inner Ear Hair Cell Damage
Inhibition of the cGAS‑STING Pathway Reduces Cisplatin-Induced Inner Ear Hair Cell Damage
Although cisplatin is a widely used chemotherapeutic agent, it is severely toxic and causes irreversible hearing loss, res...
A New Pathway Mediating Pain Sensitization after Active Sleep Deprivation
A New Pathway Mediating Pain Sensitization after Active Sleep Deprivation
Ding W, Yang L, Shi E, Kim B, Low S, Hu K. Author correction: The endocannabinoid N-arachidonoyl dopamine is critical for ...
The Current State and Future Outlook of PET Tracers for AMPA Receptors
The Current State and Future Outlook of PET Tracers for AMPA Receptors
Cao YY, Wu LL, Li XN, Yuan YL, Zhao WW, Qi JX. Molecular mechanisms of AMPA receptor trafficking in the nervous system. In...
Dysregulation of Iron Homeostasis Mediated by FTH Increases Ferroptosis Sensitivity in TP53-Mutant Glioblastoma
Dysregulation of Iron Homeostasis Mediated by FTH Increases Ferroptosis Sensitivity in TP53-Mutant Glioblastoma
Iron metabolism is a critical factor in tumorigenesis and development. Although TP53 mutations are prevalent in glioblasto...
Histaminergic Innervation of the Ventral Anterior Thalamic Nucleus Alleviates Motor Deficits in a 6-OHDA-Induced Rat Model of Parkinson’s Disease
Histaminergic Innervation of the Ventral Anterior Thalamic Nucleus Alleviates Motor Deficits in a 6-OHDA-Induced Rat Model of Parkinson’s Disease
The ventral anterior (VA) nucleus of the thalamus is a major target of the basal ganglia and is closely associated with th...
Role of the Thalamic Reticular Nucleus in Social Memory
Role of the Thalamic Reticular Nucleus in Social Memory
This highlight was supported by grants from the National Natural Science Foundation of China (32125018 and 32071005), Zhej...
Correction to: Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent Manner
Correction to: Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent Manner
Hong Chen, Gang Yang, and De-En Xu have contributed equally to this work.Department of Neurology and Clinical Research Cen...
Reprogramming miR-146b-snphb Signaling Activates Axonal Mitochondrial Transport in the Zebrafish M-cell and Facilitates Axon Regeneration After Injury
Reprogramming miR-146b-snphb Signaling Activates Axonal Mitochondrial Transport in the Zebrafish M-cell and Facilitates Axon Regeneration After Injury
Acute mitochondrial damage and the energy crisis following axonal injury highlight mitochondrial transport as an important...
A Novel Astrocyte-Neuron Interaction to Control Complex Animal Behavior
A Novel Astrocyte-Neuron Interaction to Control Complex Animal Behavior
Zhou X, Xiao Q, Liu Y, Chen S, Xu X, Zhang Z. Astrocyte-mediated regulation of BLAWFS1 neurons alleviates risk-assessment ...
NG2 Glia: The Guardians Against Prion-induced Neurotoxicity Through Prostaglandin E2 Blockade
NG2 Glia: The Guardians Against Prion-induced Neurotoxicity Through Prostaglandin E2 Blockade
Liu Y, Guo J, Matoga M, Korotkova M, Jakobsson PJ, Aguzzi A. NG2 glia protect against prion neurotoxicity by inhibiting mi...
Time-Dependent Transcriptional Dynamics of Contextual Fear Memory Retrieval Reveals the Function of Dipeptidyl Peptidase 9 in Reconsolidation
Time-Dependent Transcriptional Dynamics of Contextual Fear Memory Retrieval Reveals the Function of Dipeptidyl Peptidase 9 in Reconsolidation
Numerous studies on the formation and consolidation of memory have shown that memory processes are characterized by phase-...
Associative Learning-Induced Synaptic Potentiation at the Two Major Hippocampal CA1 Inputs for Cued Memory Acquisition
Associative Learning-Induced Synaptic Potentiation at the Two Major Hippocampal CA1 Inputs for Cued Memory Acquisition
Learning-associated functional plasticity at hippocampal synapses remains largely unexplored. Here, in a single session of...
Ventral Hippocampal CA1 GADD45B Regulates Susceptibility to Social Stress by Influencing NMDA Receptor-Mediated Synaptic Plasticity
Ventral Hippocampal CA1 GADD45B Regulates Susceptibility to Social Stress by Influencing NMDA Receptor-Mediated Synaptic Plasticity
Growth arrest DNA damage-inducible protein 45 β (GADD45B) has been reported to be a regulatory factor for active DNA ...
Alpha-synuclein Fibrils Inhibit Activation of the BDNF/ERK Signaling Loop in the mPFC to Induce Parkinson's Disease-like Alterations with Depression
Alpha-synuclein Fibrils Inhibit Activation of the BDNF/ERK Signaling Loop in the mPFC to Induce Parkinson's Disease-like Alterations with Depression
Depression (Dep) is one of the most common concomitant symptoms of Parkinson's disease (PD), but there is a lack of de...
A Novel Real-time Phase Prediction Network in EEG Rhythm
A Novel Real-time Phase Prediction Network in EEG Rhythm
Closed-loop neuromodulation, especially using the phase of the electroencephalography (EEG) rhythm to assess the real-time...
Activation of Centromedial Amygdala GABAergic Neurons Produces Hypotension in Mice
Activation of Centromedial Amygdala GABAergic Neurons Produces Hypotension in Mice
The central amygdala (CeA) is a crucial modulator of emotional, behavioral, and autonomic functions, including cardiovascu...
A Method for Detecting Depression in Adolescence Based on an Affective Brain-Computer Interface and Resting-State Electroencephalogram Signals
A Method for Detecting Depression in Adolescence Based on an Affective Brain-Computer Interface and Resting-State Electroencephalogram Signals
Depression is increasingly prevalent among adolescents and can profoundly impact their lives. However, the early detection...
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