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IsoVISoR: Towards 3D Mesoscale Brain Mapping of Large Mammals at Isotropic Sub-micron Resolution
IsoVISoR: Towards 3D Mesoscale Brain Mapping of Large Mammals at Isotropic Sub-micron Resolution
Svoboda K. The past, present, and future of single neuron reconstruction. Neuroinformatics 2011, 9: 97–98.Article  Pub...
Glutamatergic Circuits in the Pedunculopontine Nucleus Modulate Multiple Motor Functions
Glutamatergic Circuits in the Pedunculopontine Nucleus Modulate Multiple Motor Functions
The functional role of glutamatergic (vGluT2) neurons in the pedunculopontine nucleus (PPN) in modulating motor activity r...
Vascular Ossification in the Developing Brain: A Case Study of Pediatric Sturge Weber Syndrome
Vascular Ossification in the Developing Brain: A Case Study of Pediatric Sturge Weber Syndrome
Yeom S, Comi AM. Updates on sturge-weber syndrome. Stroke 2022, 53: 3769–3779.Article  PubMed  PubMed Central  ...
Sonic Hedgehog Mediates High Frequency-Dependent Deep Brain Stimulation for the Correction of Motor Deficits in a Parkinson’s Disease Model
Sonic Hedgehog Mediates High Frequency-Dependent Deep Brain Stimulation for the Correction of Motor Deficits in a Parkinson’s Disease Model
Deep brain stimulation targeting the subthalamic nucleus (STN-DBS) can relieve motor ...
YAP Signaling in Glia: Pivotal Roles in Neurological Development, Regeneration and Diseases
YAP Signaling in Glia: Pivotal Roles in Neurological Development, Regeneration and Diseases
Yes-associated protein (YAP), the key transcriptional co-factor and downstream effector of the Hippo pathway, has emerged ...
Early Postnatal Pharmacological Intervention Rescues the Disruption of Developmental Connectivity in MAO-A KO Mice
Early Postnatal Pharmacological Intervention Rescues the Disruption of Developmental Connectivity in MAO-A KO Mice
The term “developmental disconnection syndromes” (DDSs) was first coined by Geshwind ...
VTA is the Key to Pain Resilience in Empathic Behavior
VTA is the Key to Pain Resilience in Empathic Behavior
Smith ML, Hostetler CM, Heinricher MM, Ryabinin AE. Social transfer of pain in mice. Sci Adv 2016, 2: e1600855.Article  ...
Functional Connectivity Encodes Sound Locations by Lateralization Angles
Functional Connectivity Encodes Sound Locations by Lateralization Angles
The ability to localize sound sources rapidly allows human beings to efficiently understand the surrounding environment. P...
Neurodegenerative Diseases: What Can Be Learned from Toothed Whales?
Neurodegenerative Diseases: What Can Be Learned from Toothed Whales?
Neurodegeneration involves a wide range of neuropathological alterations affecting the integrity, physiology, and architec...
Right Frontal Gamma Transcranial Alternating Current Stimulation Modulates Optimism Biases
Right Frontal Gamma Transcranial Alternating Current Stimulation Modulates Optimism Biases
Sharot T, Korn CW, Dolan RJ. How unrealistic optimism is maintained in the face of reality. Nat Neurosci 2011, 14: 1475–14...
Tracing from Periphery to Cortex: Application of Herpes Simplex Virus to Somatosensory Neural Networks
Tracing from Periphery to Cortex: Application of Herpes Simplex Virus to Somatosensory Neural Networks
Liu Q, Wu Y, Wang H, Jia F, Xu F. Viral tools for neural circuit tracing. Neurosci Bull 2022, 38: 1508–1518.Article  P...
Loss of TET Activity in the Postnatal Mouse Brain Perturbs Synaptic Gene Expression and Impairs Cognitive Function
Loss of TET Activity in the Postnatal Mouse Brain Perturbs Synaptic Gene Expression and Impairs Cognitive Function
Conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) by ten-eleven translocation (TET) family proteins l...
Sex-Differential Neural Circuits and Behavioral Responses for Empathy
Sex-Differential Neural Circuits and Behavioral Responses for Empathy
This research highlight was supported by grants from the National Natural Science Foundation of China (32125018 and 320710...
Dorsal CA1 NECTIN3 Reduction Mediates Early-Life Stress-Induced Object Recognition Memory Deficits in Adolescent Female Mice
Dorsal CA1 NECTIN3 Reduction Mediates Early-Life Stress-Induced Object Recognition Memory Deficits in Adolescent Female Mice
Early-life stress (ES) leads to cognitive dysfunction in female adolescents, but the underlying neural mechanisms remain e...
A New Perspective on the Prediction and Treatment of Stroke: The Role of Uric Acid
A New Perspective on the Prediction and Treatment of Stroke: The Role of Uric Acid
Stroke, a major cerebrovascular disease, has high morbidity and mortality. Effective methods to reduce the risk and improv...
Accurate Machine Learning-based Monitoring of Anesthesia Depth with EEG Recording
Accurate Machine Learning-based Monitoring of Anesthesia Depth with EEG Recording
General anesthesia, pivotal for surgical procedures, requires precise depth monitoring to mitigate risks ranging from intr...
Constructing A Theoretical Model to Bridge Neural Transition with a State Switch in Bipolar Disorder
Constructing A Theoretical Model to Bridge Neural Transition with a State Switch in Bipolar Disorder
Rantala MJ, Luoto S, Borráz-León JI, Krams I. Bipolar disorder: An evolutionary psychoneuroimmunological approach. Neurosc...
STIM Proteins: The Gas and Brake of Calcium Entry in Neurons
STIM Proteins: The Gas and Brake of Calcium Entry in Neurons
Stromal interaction molecules (STIM)s are Ca2+ sensors in internal Ca2+ stores of the endoplasmic reticulum. They activate...
Targeting Brain Endothelial Gasdermin D: A Shortcut to Remodel the Blood-Brain Barrier
Targeting Brain Endothelial Gasdermin D: A Shortcut to Remodel the Blood-Brain Barrier
Yao D, Zhang R, Xie M, Ding F, Wang M, Wang W. Updated understanding of the glial-vascular unit in central nervous system ...
Spatiotemporal Mapping of the Oxytocin Receptor at Single-Cell Resolution in the Postnatally Developing Mouse Brain
Spatiotemporal Mapping of the Oxytocin Receptor at Single-Cell Resolution in the Postnatally Developing Mouse Brain
The oxytocin receptor (OXTR) has garnered increasing attention for its role in regulating both mature behaviors and brain ...
Melatonin Ameliorates Abnormal Sleep-Wake Behavior via Facilitating Lipid Metabolism in a Zebrafish Model of Parkinson’s Disease
Melatonin Ameliorates Abnormal Sleep-Wake Behavior via Facilitating Lipid Metabolism in a Zebrafish Model of Parkinson’s Disease
Sleep-wake disorder is one of the most common nonmotor symptoms of Parkinson's disease (PD). Melatonin has the potenti...
Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent Manner
Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent Manner
Oligodendrocyte lineage cells, including oligodendrocyte precursor cells (OPCs) and oligodendrocytes (OLs), are essential ...
GABAergic Retinal Ganglion Cells Projecting to the Superior Colliculus Mediate the Looming-Evoked Flight Response
GABAergic Retinal Ganglion Cells Projecting to the Superior Colliculus Mediate the Looming-Evoked Flight Response
The looming stimulus-evoked flight response to approaching predators is a defensive behavior in most animals. However, how...
Memory Reconsolidation Updating in Substance Addiction: Applications, Mechanisms, and Future Prospects for Clinical Therapeutics
Memory Reconsolidation Updating in Substance Addiction: Applications, Mechanisms, and Future Prospects for Clinical Therapeutics
Persistent and maladaptive drug-related memories represent a key component in drug addiction. Converging evidence from bot...
Progress of the Impact of Terahertz Radiation on Ion Channel Kinetics in Neuronal Cells
Progress of the Impact of Terahertz Radiation on Ion Channel Kinetics in Neuronal Cells
In neurons and myocytes, selective ion channels in the plasma membrane play a pivotal role in transducing chemical or sens...
Unlocking the Mysteries of the Subcommissural Organ: A Patron Saint of Neuronal Development
Unlocking the Mysteries of the Subcommissural Organ: A Patron Saint of Neuronal Development
Kaur C, Ling EA. The circumventricular organs. Histol Histopathol 2017, 32: 879–892.PubMed  Googl...
Acute Recruitment of VTA Dopamine Neurons by mPOA Esr1+ Neurons to Facilitate Consummatory Male Mating Actions
Acute Recruitment of VTA Dopamine Neurons by mPOA Esr1+ Neurons to Facilitate Consummatory Male Mating Actions
Tinbergen N (1989) The study of instinct. Clarendon Press, Oxford. Google Scholar  Len...
A Machine Learning Approach for Behavioral Recognition of Stress Levels in Mice
A Machine Learning Approach for Behavioral Recognition of Stress Levels in Mice
Seo JS, Wei J, Qin L, Kim Y, Yan Z, Greengard P. Cellular and molecular basis for stress-induced depression. Mol Psychiatr...
SARS-CoV-2 Inhibits Exo-Endocytosis and Enhances Short-Term Depression at a Central Synapse
SARS-CoV-2 Inhibits Exo-Endocytosis and Enhances Short-Term Depression at a Central Synapse
Zhu C, Zhang T, Li Q, Chen X, Wang K. Depression and anxiety during the COVID-19 pandemic: epidemiology, mechanism, and tr...
Rhythm Facilitates Auditory Working Memory via Beta-Band Encoding and Theta-Band Maintenance
Rhythm Facilitates Auditory Working Memory via Beta-Band Encoding and Theta-Band Maintenance
Rhythm, as a prominent characteristic of auditory experiences such as speech and music, is known to facilitate attention, ...
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